TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

Pharmacology and Therapeutics

Volumn 177, Issue , 2017, Pages 81-95

  Tammaro, Alessandra ^a   Derive, Marc ^b   Gibot, Sebastien ^c,d   Leemans, Jaklien C ^a   Florquin, Sandrine ^a,e   Dessing, Mark C ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b INOTREM SA   (France)

^c UNIVERSITY HOSPITAL OF NANCY   (France)

^d UNIVERSITÉ DE LORRAINE   (France)

^e RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Non infectious inflammatory diseases; TLR NLR pathway; TREM 1 inhibitors; TREM 1 ligands; Triggering receptor expressed on myeloid cells 1

Indexed keywords

HEAT SHOCK PROTEIN 70; HIGH MOBILITY GROUP B1 PROTEIN; LP17 PEPTIDE; LR12 PEPTIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; PATHOGEN ASSOCIATED MOLECULAR PATTERN; PEPTIDE; PEPTIDOGLYCAN RECOGNITION PROTEIN; PEPTIDOGLYCAN RECOGNITION RECEPTOR 1; TOLL LIKE RECEPTOR; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; UNCLASSIFIED DRUG; LIGAND;

ATHEROSCLEROSIS; BINDING SITE; BONE MARROW CELL; CELL MIGRATION; CELL SURVIVAL; CHRONIC INFLAMMATION; COLITIS; DISEASE ASSOCIATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; FIBROSIS; GOUT; GRANULOCYTE; HEMORRHAGIC SHOCK; HUMAN; IMMUNOCOMPETENT CELL; INFECTION; INNATE IMMUNITY; LIGAND BINDING; MACROPHAGE; MALIGNANT NEOPLASM; MOLECULAR WEIGHT; NEUTROPHIL GRANULE; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSORIASIS; REPERFUSION INJURY; REPORTER GENE; REVIEW; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SURFACE PLASMON RESONANCE; TISSUE INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; GENETICS; INFLAMMATION; METABOLISM;

ANIMALS; HUMANS; INFLAMMATION; LIGANDS; SIGNAL TRANSDUCTION; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS-1;

EID: 85014137005     PISSN: 01637258     EISSN: 1879016X     Source Type: Journal    
DOI: 10.1016/j.pharmthera.2017.02.043     Document Type: Review

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