TREM-1 expression in tumor-associated macrophages and clinical outcome in lung cancer

American Journal of Respiratory and Critical Care Medicine

Volumn 177, Issue 7, 2008, Pages 763-770

  Ho, Chao Chi ^a   Liao, Wei Yu ^a   Wang, Cheng Yi ^b   Lu, Yin Hsiu ^c   Huang, Hsin Yi ^a   Chen, Hsuan Yu ^c,d   Chan, Wing Kai ^a   Chen, Huei Wen ^e   Yang, Pan Chyr ^a  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d INSTITUTE OF STATISTICAL SCIENCE   (Taiwan)

^e NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Inflammation; Macrophage; Non small cell lung cancer; TREM 1

Indexed keywords

INTERLEUKIN 1BETA; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR ALPHA; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; TREM1 PROTEIN, HUMAN; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER GROWTH; CANCER SURVIVAL; CELL CULTURE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PLEURA EFFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR ASSOCIATED LEUKOCYTE; WESTERN BLOTTING; DISEASE COURSE; IMMUNOLOGY; INFLAMMATION; KAPLAN MEIER METHOD; LUNG TUMOR; MACROPHAGE; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; UPREGULATION;

CARCINOMA, NON-SMALL-CELL LUNG; DISEASE PROGRESSION; FEMALE; HUMANS; INFLAMMATION; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PLEURAL EFFUSION; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RECEPTORS, IMMUNOLOGIC; UP-REGULATION;

EID: 41749104887     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200704-641OC     Document Type: Article

References (40)

1. Sporn MB. The war on cancer. Lancet 1996;347:1377-1381.
2. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
3. Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-867.
4. Crowther M, Brown NJ, Bishop ET, Lewis CE. Microenvironmental influence on macrophage regulation of angiogenesis in wounds and malignant tumors. J Leukoc Biol 2001;70:478-490.
5. Lin EY, Nguyen AV, Russell RG, Pollard JW. Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J Exp Med 2001;193:727-740.
6. Mantovani A. Cancer inflammation by remote control. Nature 2005;435:752-753.
7. Pollard JW. Tumour-educated macrophages promote tumour progression and metastasis. Nat Rev Cancer 2004;4:71-78.
8. Bouchon A, Dietrich J, Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol 2000;164:4991-4995.
9. Bouchon A, Facchetti F, Weigand MA, Colonna M. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 2001;410:1103-1107.
10. Gibot S, Cravoisy A, Kolopp-Sarda MN, Bene MC, Faure G, Bollaert PE, Levy B. Time-course of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis. Crit Care Med 2005;33:792-796.
11. Gibot S, Cravoisy A, Levy B, Bene M-C, Faure G, Bollaert P-E. Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia. N Engl J Med 2004;350:451-458.
12. Gibot S, Kolopp-Sarda M-N, Bene MC, Cravoisy A, Levy B, Faure GC, Bollaert P-E. Plasma level of a triggering receptor expressed on myeloid cells-1: its diagnostic accuracy in patients with suspected sepsis. Ann Intern Med 2004;141:9-15.
13. Gibot S, Kolopp-Sarda M-N, Bene M-C, Bollaert P-E, Lozniewski A, Mory F, Levy B, Faure GC. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J Exp Med 2004;200:1419-1426.
14. Nathan C, Ding A. TREM-1: a new regulator of innate immunity in sepsis syndrome. Nat Med 2001;7:530-532.
15. Gonzalez-Roldan N, Ferat-Osorio E, Aduna-Vicente R, Wong-Baeza I, Esquivel-Callejas N, Astudillo-de la Vega H, Sanchez-Fernandez P, Arriaga-Pizano L, Villasis-Keever MA, Lopez-Macias C, et al. Expression of triggering receptor on myeloid cell 1 and histocompatibility complex molecules in sepsis and major abdominal surgery. World J Gastroenterol 2005;11:7473-7479.
16. Koussoulas V, Vassiliou S, Demonakou M, Tassias G, Giamarellos-Bourboulis EJ, Mouktaroudi M, Giamarellou H, Barbatzas C. Soluble triggering receptor expressed on myeloid cells (sTREM-1): a new mediator involved in the pathogenesis of peptic ulcer disease. Eur J Gastroenterol Hepatol 2006;18:375-379.
17. Wang DY, Qin RY, Liu ZR, Gupta MK, Chang Q. Expression of TREM-1 mRNA in acute pancreatitis. World J Gastroenterol 2004;10:2744-2746.
18. Dietrich J, Cella M, Seiffert M, Buhring H-J, Colonna M. Cutting edge: signal-regulatory protein β1 is a DAP12-associated activating receptor expressed in myeloid cells. J Immunol 2000;164:9-12.
19. Gingras M-C, Lapillonne H, Margolin JF. TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development. Mol Immunol 2002;38:817-824.
20. Bleharski JR, Kiessler V, Buonsanti C, Sieling PA, Stenger S, Colonna M, Modlin RL. A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J Immunol 2003;170:3812-3818.
21. Colonna M. TREMs in the immune system and beyond. Nat Rev Immunol 2003;3:445-453.
22. Chen JJW, Peck K, Hong T-M, Yang S-C, Sher Y-P, Shih J-Y, Wu R, Cheng J-L, Roffler SR, Wu C-W, et al. Global analysis of gene expression in invasion by a lung cancer model. Cancer Res 2001;61:5223-5230.
23. Shih J-Y, Yang S-C, Hong T-M, Yuan A, Chen JJW, Yu C-J, Chang Y-L, Lee Y-C, Peck K, Wu C-W, et al. Collapsin response mediator protein-1 and the invasion and metastasis of cancer cells. J Natl Cancer Inst 2001;93:1392-1400.
24. Mohamadzadeh M, Coberley SS, Olinger GG, Kalina WV, Ruthel G, Fuller CL, Swenson DL, Pratt WD, Kuhns DB, Schmaljohn AL. Activation of triggering receptor expressed on myeloid cells-1 on human neutrophils by Marburg and ebola viruses. J Virol 2006;80:7235-7244.
25. Albini A, Iwamoto Y, Kleinman HK, Martin GR, Aaronson SA, Kozlowski JM, McEwan RN. A rapid in vitro assay for quantitating the invasive potential of tumor cells. Cancer Res 1987;47:3239-3245.
26. Chen JJW, Lin Y-C, Yao P-L, Yuan A, Chen H-Y, Shun C-T, Tsai M-F, Chen C-H, Yang P-C. Tumor-associated macrophages: the double-edged sword in cancer progression. J Clin Oncol 2005;23:953-964.
27. Takanami I, Takeuchi K, Kodaira S. Tumor-associated macrophage infiltration in pulmonary adenocarcinoma: association with angiogenesis and poor prognosis. Oncology 1999;57:138-142.
28. Chen JJW, Yao P-L, Yuan A, Hong T-M, Shun C-T, Kuo M-L, Lee Y-C, Yang P-C. Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 2003;9:729-737.
29. Balkwill F, Mantovani A. Inflammation and cancer: back to Virchow? Lancet 2001;357:539-545.
30. Mantovani A, Sozzani S, Locati M, Allavena P, Sica A. Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 2002;23:549-555.
31. Balkwill F, Osborne R, Burke F, Naylor S, Talbot D, Durbin H, Tavernier J, Fiers W. Evidence for tumour necrosis factor/cachectin production in cancer. Lancet 1987;2:1229-1232.
32. Guadagni F, Ferroni P, Basili S, Facciolo F, Carlini S, Crecco M, Martini F, Spila A, D'Alessandro R, Aloe S. Correlation between tumor necrosis factor-alpha and -dimer levels in non-small cell lung cancer patients. Lung Cancer 2004;44:303-310.
33. Kaminska J, Kowalska M, Kotowicz B, Fuksiewicz M, Glogowski M, Wojcik E, Chechlinska M, Steffen J. Pretreatment serum levels of cytokines and cytokine receptors in patients with non-small cell lung cancer, and correlations with clinicopathological features and prognosis. M-CSF: an independent prognostic factor. Oncology 2006;70:115-125.
34. Matanic D, Beg-Zec Z, Stojanovic D, Matakoric N, Flego V, Milevoj-Ribic F. Cytokines in patients with lung cancer. Scand J Immunol 2003;57:173-178.
35. Trejo YG, Bordenave RH, Beviacqua M, Rumi LS. In vitro secretion of cytokines and prostaglandin-E2 by monocytes fromlung cancer patients. Respir Med 2001;95:243-245.
36. Trejo YG, Bordenave RH, Beviacqua M, Zanoni L, Rumi LS. Tumor necrosis factor-alfa production by monocytes from lung and colorectal cancer patients. J Exp Clin Cancer Res 2001;20:71-73.
37. Voronov E, Shouval DS, Krelin Y, Cagnano E, Benharroch D, Iwakura Y, Dinarello CA, Apte RN. IL-1 is required for tumor invasiveness and angiogenesis. Proc Natl Acad Sci USA 2003;100:2645-2650.
38. Yao P-L, Lin Y-C, Wang C-H, Huang Y-C, Liao W-Y, Wang S-S, Chen JJW, Yang P-C. Autocrine and paracrine regulation of interleukin-8 expression in lung cancer cells. Am J Respir Cell Mol Biol 2005;32:540-547.
39. Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, et al. HIF-1[alpha] is essential for myeloid cell-mediated inflammation. Cell 2003;112:645-657.
40. Chen K-Y, Chang C-H, Yu C-J, Kuo S-H, Yang P-C. Distribution according to histologic type and outcome by gender and age group in Taiwanese patients with lung carcinoma. Cancer 2005;103:2566-2574.