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Volumn 213, Issue 9-10, 2008, Pages 701-713

From expression to signaling: Roles of TREM-1 and TREM-2 in innate immunity and bacterial infection

Author keywords

Bacterial infection; Innate immunity; TREM 1; TREM 2

Indexed keywords

LIGAND; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG;

EID: 52949142215     PISSN: 01712985     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.imbio.2008.07.008     Document Type: Review
Times cited : (172)

References (67)
  • 1
    • 0037331539 scopus 로고    scopus 로고
    • The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44
    • Allcock R.J., Barrow A.D., Forbes S., Beck S., and Trowsdale J. The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. Eur. J. Immunol. 33 (2003) 567-577
    • (2003) Eur. J. Immunol. , vol.33 , pp. 567-577
    • Allcock, R.J.1    Barrow, A.D.2    Forbes, S.3    Beck, S.4    Trowsdale, J.5
  • 2
    • 2142660776 scopus 로고    scopus 로고
    • Differential regulation of DAP12 and molecules associated with DAP12 during host responses to mycobacterial infection
    • Aoki N., Zganiacz A., Margetts P., and Xing Z. Differential regulation of DAP12 and molecules associated with DAP12 during host responses to mycobacterial infection. Infect. Immun. 72 (2004) 2477-2483
    • (2004) Infect. Immun. , vol.72 , pp. 2477-2483
    • Aoki, N.1    Zganiacz, A.2    Margetts, P.3    Xing, Z.4
  • 3
    • 34548442991 scopus 로고    scopus 로고
    • Coordinating TLR-activated signaling pathways in cells of the immune system
    • Banerjee A., and Gerondakis S. Coordinating TLR-activated signaling pathways in cells of the immune system. Immunol. Cell Biol. 85 (2007) 420-424
    • (2007) Immunol. Cell Biol. , vol.85 , pp. 420-424
    • Banerjee, A.1    Gerondakis, S.2
  • 4
    • 2442450439 scopus 로고    scopus 로고
    • Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2
    • Barrow A.D., Astoul E., Floto A., Brooke G., Relou I.A., Jennings N.S., Smith K.G., Ouwehand W., Farndale R.W., Alexander D.R., and Trowsdale J. Cutting edge: TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2. J. Immunol. 172 (2004) 5838-5842
    • (2004) J. Immunol. , vol.172 , pp. 5838-5842
    • Barrow, A.D.1    Astoul, E.2    Floto, A.3    Brooke, G.4    Relou, I.A.5    Jennings, N.S.6    Smith, K.G.7    Ouwehand, W.8    Farndale, R.W.9    Alexander, D.R.10    Trowsdale, J.11
  • 6
    • 35748967851 scopus 로고    scopus 로고
    • High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity
    • Bianchi M.E., and Manfredi A.A. High-mobility group box 1 (HMGB1) protein at the crossroads between innate and adaptive immunity. Immunol. Rev. 220 (2007) 35-46
    • (2007) Immunol. Rev. , vol.220 , pp. 35-46
    • Bianchi, M.E.1    Manfredi, A.A.2
  • 7
    • 0346665750 scopus 로고    scopus 로고
    • A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response
    • Bleharski J.R., Kiessler V., Buonsanti C., Sieling P.A., Stenger S., Colonna M., and Modlin R.L. A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J. Immunol. 170 (2003) 3812-3818
    • (2003) J. Immunol. , vol.170 , pp. 3812-3818
    • Bleharski, J.R.1    Kiessler, V.2    Buonsanti, C.3    Sieling, P.A.4    Stenger, S.5    Colonna, M.6    Modlin, R.L.7
  • 8
    • 0034657890 scopus 로고    scopus 로고
    • Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes
    • Bouchon A., Dietrich J., and Colonna M. Cutting edge: inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J. Immunol. 164 (2000) 4991-4995
    • (2000) J. Immunol. , vol.164 , pp. 4991-4995
    • Bouchon, A.1    Dietrich, J.2    Colonna, M.3
  • 9
    • 0035953547 scopus 로고    scopus 로고
    • TREM-1 amplifies inflammation and is a crucial mediator of septic shock
    • Bouchon A., Facchetti F., Weigand M.A., and Colonna M. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 410 (2001) 1103-1107
    • (2001) Nature , vol.410 , pp. 1103-1107
    • Bouchon, A.1    Facchetti, F.2    Weigand, M.A.3    Colonna, M.4
  • 10
    • 0035887503 scopus 로고    scopus 로고
    • A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells
    • Bouchon A., Hernandez-Munain C., Cella M., and Colonna M. A DAP12-mediated pathway regulates expression of CC chemokine receptor 7 and maturation of human dendritic cells. J. Exp. Med. 194 (2001) 1111-1122
    • (2001) J. Exp. Med. , vol.194 , pp. 1111-1122
    • Bouchon, A.1    Hernandez-Munain, C.2    Cella, M.3    Colonna, M.4
  • 11
    • 11244285329 scopus 로고    scopus 로고
    • Constitutive and interleukin-1-inducible phosphorylation of p65 NF-kappaB at serine 536 is mediated by multiple protein kinases including IkappaB kinase (IKK)-alpha, IKKbeta, IKKepsilon, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription
    • Buss H., Dorrie A., Schmitz M.L., Hoffmann E., Resch K., and Kracht M. Constitutive and interleukin-1-inducible phosphorylation of p65 NF-kappaB at serine 536 is mediated by multiple protein kinases including IkappaB kinase (IKK)-alpha, IKKbeta, IKKepsilon, TRAF family member-associated (TANK)-binding kinase 1 (TBK1), and an unknown kinase and couples p65 to TATA-binding protein-associated factor II31-mediated interleukin-8 transcription. J. Biol. Chem. 279 (2004) 55633-55643
    • (2004) J. Biol. Chem. , vol.279 , pp. 55633-55643
    • Buss, H.1    Dorrie, A.2    Schmitz, M.L.3    Hoffmann, E.4    Resch, K.5    Kracht, M.6
  • 12
    • 40949118589 scopus 로고    scopus 로고
    • Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia
    • Chen L.C., Laskin J.D., Gordon M.K., and Laskin D.L. Regulation of TREM expression in hepatic macrophages and endothelial cells during acute endotoxemia. Exp. Mol. Pathol. 84 (2007) 145-155
    • (2007) Exp. Mol. Pathol. , vol.84 , pp. 145-155
    • Chen, L.C.1    Laskin, J.D.2    Gordon, M.K.3    Laskin, D.L.4
  • 13
    • 0036149766 scopus 로고    scopus 로고
    • Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17
    • Chung D.H., Seaman W.E., and Daws M.R. Characterization of TREM-3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17. Eur. J. Immunol. 32 (2002) 59-66
    • (2002) Eur. J. Immunol. , vol.32 , pp. 59-66
    • Chung, D.H.1    Seaman, W.E.2    Daws, M.R.3
  • 14
    • 0038687056 scopus 로고    scopus 로고
    • TREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses
    • Colonna M., and Facchetti F. TREM-1 (triggering receptor expressed on myeloid cells): a new player in acute inflammatory responses. J. Infect. Dis. 187 Suppl. 2 (2003) S397-S401
    • (2003) J. Infect. Dis. , vol.187 , Issue.SUPPL. 2
    • Colonna, M.1    Facchetti, F.2
  • 16
    • 0035086799 scopus 로고    scopus 로고
    • Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family
    • Daws M.R., Lanier L.L., Seaman W.E., and Ryan J.C. Cloning and characterization of a novel mouse myeloid DAP12-associated receptor family. Eur. J. Immunol. 31 (2001) 783-791
    • (2001) Eur. J. Immunol. , vol.31 , pp. 783-791
    • Daws, M.R.1    Lanier, L.L.2    Seaman, W.E.3    Ryan, J.C.4
  • 18
    • 34347347039 scopus 로고    scopus 로고
    • Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin
    • El Mezayen R., El Gazzar M., Seeds M.C., McCall C.E., Dreskin S.C., and Nicolls M.R. Endogenous signals released from necrotic cells augment inflammatory responses to bacterial endotoxin. Immunol. Lett. 111 (2007) 36-44
    • (2007) Immunol. Lett. , vol.111 , pp. 36-44
    • El Mezayen, R.1    El Gazzar, M.2    Seeds, M.C.3    McCall, C.E.4    Dreskin, S.C.5    Nicolls, M.R.6
  • 19
    • 33845863646 scopus 로고    scopus 로고
    • Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4
    • Fortin C.F., Lesur O., and Fulop Jr. T. Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4. Int. Immunol. 19 (2007) 41-50
    • (2007) Int. Immunol. , vol.19 , pp. 41-50
    • Fortin, C.F.1    Lesur, O.2    Fulop Jr., T.3
  • 20
    • 27744574400 scopus 로고    scopus 로고
    • Soluble form of the triggering receptor expressed on myeloid cells-1 as a marker of microbial infection
    • Gibot S., and Cravoisy A. Soluble form of the triggering receptor expressed on myeloid cells-1 as a marker of microbial infection. Clin. Med. Res. 2 (2004) 181-187
    • (2004) Clin. Med. Res. , vol.2 , pp. 181-187
    • Gibot, S.1    Cravoisy, A.2
  • 21
    • 10644237032 scopus 로고    scopus 로고
    • A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis
    • Gibot S., Kolopp-Sarda M.N., Bene M.C., Bollaert P.E., Lozniewski A., Mory F., Levy B., and Faure G.C. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J. Exp. Med. 200 (2004) 1419-1426
    • (2004) J. Exp. Med. , vol.200 , pp. 1419-1426
    • Gibot, S.1    Kolopp-Sarda, M.N.2    Bene, M.C.3    Bollaert, P.E.4    Lozniewski, A.5    Mory, F.6    Levy, B.7    Faure, G.C.8
  • 25
    • 0036193740 scopus 로고    scopus 로고
    • TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development
    • Gingras M.C., Lapillonne H., and Margolin J.F. TREM-1, MDL-1, and DAP12 expression is associated with a mature stage of myeloid development. Mol. Immunol. 38 (2002) 817-824
    • (2002) Mol. Immunol. , vol.38 , pp. 817-824
    • Gingras, M.C.1    Lapillonne, H.2    Margolin, J.F.3
  • 27
    • 33746875981 scopus 로고    scopus 로고
    • Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12
    • Hamerman J.A., Jarjoura J.R., Humphrey M.B., Nakamura M.C., Seaman W.E., and Lanier L.L. Cutting edge: inhibition of TLR and FcR responses in macrophages by triggering receptor expressed on myeloid cells (TREM)-2 and DAP12. J. Immunol. 177 (2006) 2051-2055
    • (2006) J. Immunol. , vol.177 , pp. 2051-2055
    • Hamerman, J.A.1    Jarjoura, J.R.2    Humphrey, M.B.3    Nakamura, M.C.4    Seaman, W.E.5    Lanier, L.L.6
  • 31
    • 33745620179 scopus 로고    scopus 로고
    • Sepsis under siege: a new understanding of sepsis might lead to the development of therapies to treat septic shock
    • Hunter P. Sepsis under siege: a new understanding of sepsis might lead to the development of therapies to treat septic shock. EMBO Rep. 7 (2006) 667-669
    • (2006) EMBO Rep. , vol.7 , pp. 667-669
    • Hunter, P.1
  • 32
    • 35348932070 scopus 로고    scopus 로고
    • Intracellular NOD-like receptors in host defense and disease
    • Kanneganti T.D., Lamkanfi M., and Nunez G. Intracellular NOD-like receptors in host defense and disease. Immunity 27 (2007) 549-559
    • (2007) Immunity , vol.27 , pp. 549-559
    • Kanneganti, T.D.1    Lamkanfi, M.2    Nunez, G.3
  • 33
    • 9244259688 scopus 로고    scopus 로고
    • Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76A
    • Kelker M.S., Debler E.W., and Wilson I.A. Crystal structure of mouse triggering receptor expressed on myeloid cells 1 (TREM-1) at 1.76A. J. Mol. Biol. 344 (2004) 1175-1181
    • (2004) J. Mol. Biol. , vol.344 , pp. 1175-1181
    • Kelker, M.S.1    Debler, E.W.2    Wilson, I.A.3
  • 34
    • 33646485691 scopus 로고    scopus 로고
    • Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation
    • King R.G., Herrin B.R., and Justement L.B. Trem-like transcript 2 is expressed on cells of the myeloid/granuloid and B lymphoid lineage and is up-regulated in response to inflammation. J. Immunol. 176 (2006) 6012-6021
    • (2006) J. Immunol. , vol.176 , pp. 6012-6021
    • King, R.G.1    Herrin, B.R.2    Justement, L.B.3
  • 35
    • 33846316333 scopus 로고    scopus 로고
    • The TREM receptor family and signal integration
    • Klesney-Tait J., Turnbull I.R., and Colonna M. The TREM receptor family and signal integration. Nat. Immunol. 7 (2006) 1266-1273
    • (2006) Nat. Immunol. , vol.7 , pp. 1266-1273
    • Klesney-Tait, J.1    Turnbull, I.R.2    Colonna, M.3
  • 37
    • 10344245540 scopus 로고    scopus 로고
    • Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia
    • Knapp S., Gibot S., de Vos A., Versteeg H.H., Colonna M., and van der Poll T. Cutting edge: expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia. J. Immunol. 173 (2004) 7131-7134
    • (2004) J. Immunol. , vol.173 , pp. 7131-7134
    • Knapp, S.1    Gibot, S.2    de Vos, A.3    Versteeg, H.H.4    Colonna, M.5    van der Poll, T.6
  • 39
    • 34548436187 scopus 로고    scopus 로고
    • The negative regulation of Toll-like receptor and associated pathways
    • Lang T., and Mansell A. The negative regulation of Toll-like receptor and associated pathways. Immunol. Cell Biol. 85 (2007) 425-434
    • (2007) Immunol. Cell Biol. , vol.85 , pp. 425-434
    • Lang, T.1    Mansell, A.2
  • 41
    • 33846240914 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced up-regulation of triggering receptor expressed on myeloid cells-1 expression on macrophages is regulated by endogenous prostaglandin E2
    • Murakami Y., Kohsaka H., Kitasato H., and Akahoshi T. Lipopolysaccharide-induced up-regulation of triggering receptor expressed on myeloid cells-1 expression on macrophages is regulated by endogenous prostaglandin E2. J. Immunol. 178 (2007) 1144-1150
    • (2007) J. Immunol. , vol.178 , pp. 1144-1150
    • Murakami, Y.1    Kohsaka, H.2    Kitasato, H.3    Akahoshi, T.4
  • 42
    • 33845456631 scopus 로고    scopus 로고
    • Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors
    • Netea M.G., Azam T., Ferwerda G., Girardin S.E., Kim S.H., and Dinarello C.A. Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. J. Leukoc. Biol. 80 (2006) 1454-1461
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 1454-1461
    • Netea, M.G.1    Azam, T.2    Ferwerda, G.3    Girardin, S.E.4    Kim, S.H.5    Dinarello, C.A.6
  • 44
    • 33845768987 scopus 로고    scopus 로고
    • Integrating cell-signalling pathways with NF-kappaB and IKK function
    • Perkins N.D. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat. Rev. Mol. Cell Biol. 8 (2007) 49-62
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , pp. 49-62
    • Perkins, N.D.1
  • 46
    • 0344234282 scopus 로고    scopus 로고
    • Crystal structure of the human myeloid cell activating receptor TREM-1
    • Radaev S., Kattah M., Rostro B., Colonna M., and Sun P.D. Crystal structure of the human myeloid cell activating receptor TREM-1. Structure 11 (2003) 1527-1535
    • (2003) Structure , vol.11 , pp. 1527-1535
    • Radaev, S.1    Kattah, M.2    Rostro, B.3    Colonna, M.4    Sun, P.D.5
  • 47
    • 4644292514 scopus 로고    scopus 로고
    • Characterization of bovine cDNA encoding triggering receptor expressed on myeloid cells 1 (TREM-1)
    • Ramanathan B., Minton J.E., Ross C.R., and Blecha F. Characterization of bovine cDNA encoding triggering receptor expressed on myeloid cells 1 (TREM-1). Vet. Immunol. Immunopathol. 102 (2004) 85-89
    • (2004) Vet. Immunol. Immunopathol. , vol.102 , pp. 85-89
    • Ramanathan, B.1    Minton, J.E.2    Ross, C.R.3    Blecha, F.4
  • 48
    • 4344643389 scopus 로고    scopus 로고
    • Cloning of porcine triggering receptor expressed on myeloid cells-1 (TREM-1) and its induction by lipopolysaccharide, peptidoglycan, and Salmonella enterica serovar Typhimurium infection
    • Ramanathan B., Minton J.E., Ross C.R., and Blecha F. Cloning of porcine triggering receptor expressed on myeloid cells-1 (TREM-1) and its induction by lipopolysaccharide, peptidoglycan, and Salmonella enterica serovar Typhimurium infection. Dev. Comp. Immunol. 29 (2005) 1-7
    • (2005) Dev. Comp. Immunol. , vol.29 , pp. 1-7
    • Ramanathan, B.1    Minton, J.E.2    Ross, C.R.3    Blecha, F.4
  • 51
    • 10844268749 scopus 로고    scopus 로고
    • Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine
    • Schenk M., Bouchon A., Birrer S., Colonna M., and Mueller C. Macrophages expressing triggering receptor expressed on myeloid cells-1 are underrepresented in the human intestine. J. Immunol. 174 (2005) 517-524
    • (2005) J. Immunol. , vol.174 , pp. 517-524
    • Schenk, M.1    Bouchon, A.2    Birrer, S.3    Colonna, M.4    Mueller, C.5
  • 53
    • 9644307970 scopus 로고    scopus 로고
    • Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia
    • Sessa G., Podini P., Mariani M., Meroni A., Spreafico R., Sinigaglia F., Colonna M., Panina P., and Meldolesi J. Distribution and signaling of TREM2/DAP12, the receptor system mutated in human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy dementia. Eur. J. Neurosci. 20 (2004) 2617-2628
    • (2004) Eur. J. Neurosci. , vol.20 , pp. 2617-2628
    • Sessa, G.1    Podini, P.2    Mariani, M.3    Meroni, A.4    Spreafico, R.5    Sinigaglia, F.6    Colonna, M.7    Panina, P.8    Meldolesi, J.9
  • 54
    • 33846850216 scopus 로고    scopus 로고
    • Transcriptional profiling of the LPS induced NF-kappaB response in macrophages
    • Sharif O., Bolshakov V.N., Raines S., Newham P., and Perkins N.D. Transcriptional profiling of the LPS induced NF-kappaB response in macrophages. BMC Immunol. 8 (2007) 1
    • (2007) BMC Immunol. , vol.8 , pp. 1
    • Sharif, O.1    Bolshakov, V.N.2    Raines, S.3    Newham, P.4    Perkins, N.D.5
  • 55
    • 0033580935 scopus 로고    scopus 로고
    • CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis
    • Srinivasula S.M., Ahmad M., Lin J.H., Poyet J.L., Fernandes-Alnemri T., Tsichlis P.N., and Alnemri E.S. CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. J. Biol. Chem. 274 (1999) 17946-17954
    • (1999) J. Biol. Chem. , vol.274 , pp. 17946-17954
    • Srinivasula, S.M.1    Ahmad, M.2    Lin, J.H.3    Poyet, J.L.4    Fernandes-Alnemri, T.5    Tsichlis, P.N.6    Alnemri, E.S.7
  • 56
    • 14244268775 scopus 로고    scopus 로고
    • Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2
    • Takahashi K., Rochford C.D., and Neumann H. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. J. Exp. Med. 201 (2005) 647-657
    • (2005) J. Exp. Med. , vol.201 , pp. 647-657
    • Takahashi, K.1    Rochford, C.D.2    Neumann, H.3
  • 58
    • 33846914416 scopus 로고    scopus 로고
    • Non-T cell activation linker (NTAL) negatively regulates TREM-1/DAP12-induced inflammatory cytokine production in myeloid cells
    • Tessarz A.S., Weiler S., Zanzinger K., Angelisova P., Horejsi V., and Cerwenka A. Non-T cell activation linker (NTAL) negatively regulates TREM-1/DAP12-induced inflammatory cytokine production in myeloid cells. J. Immunol. 178 (2007) 1991-1999
    • (2007) J. Immunol. , vol.178 , pp. 1991-1999
    • Tessarz, A.S.1    Weiler, S.2    Zanzinger, K.3    Angelisova, P.4    Horejsi, V.5    Cerwenka, A.6
  • 59
    • 33846562134 scopus 로고    scopus 로고
    • Activating and inhibitory functions of DAP12
    • Turnbull I.R., and Colonna M. Activating and inhibitory functions of DAP12. Nat. Rev. Immunol. 7 (2007) 155-161
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 155-161
    • Turnbull, I.R.1    Colonna, M.2
  • 60
    • 23744513114 scopus 로고    scopus 로고
    • DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis
    • Turnbull I.R., McDunn J.E., Takai T., Townsend R.R., Cobb J.P., and Colonna M. DAP12 (KARAP) amplifies inflammation and increases mortality from endotoxemia and septic peritonitis. J. Exp. Med. 202 (2005) 363-369
    • (2005) J. Exp. Med. , vol.202 , pp. 363-369
    • Turnbull, I.R.1    McDunn, J.E.2    Takai, T.3    Townsend, R.R.4    Cobb, J.P.5    Colonna, M.6
  • 62
    • 11844269840 scopus 로고    scopus 로고
    • Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation
    • Viatour P., Merville M.P., Bours V., and Chariot A. Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. Trends Biochem. Sci. 30 (2005) 43-52
    • (2005) Trends Biochem. Sci. , vol.30 , pp. 43-52
    • Viatour, P.1    Merville, M.P.2    Bours, V.3    Chariot, A.4
  • 63
    • 33645453052 scopus 로고    scopus 로고
    • The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L
    • Viertlboeck B.C., Schmitt R., and Gobel T.W. The chicken immunoregulatory receptor families SIRP, TREM, and CMRF35/CD300L. Immunogenetics 58 (2006) 180-190
    • (2006) Immunogenetics , vol.58 , pp. 180-190
    • Viertlboeck, B.C.1    Schmitt, R.2    Gobel, T.W.3
  • 64
    • 3843070946 scopus 로고    scopus 로고
    • A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets
    • Washington A.V., Schubert R.L., Quigley L., Disipio T., Feltz R., Cho E.H., and McVicar D.W. A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets. Blood 104 (2004) 1042-1047
    • (2004) Blood , vol.104 , pp. 1042-1047
    • Washington, A.V.1    Schubert, R.L.2    Quigley, L.3    Disipio, T.4    Feltz, R.5    Cho, E.H.6    McVicar, D.W.7
  • 65
    • 33645958613 scopus 로고    scopus 로고
    • TIR, CARD and PYRIN: three domains for an antimicrobial triad
    • Werts C., Girardin S.E., and Philpott D.J. TIR, CARD and PYRIN: three domains for an antimicrobial triad. Cell Death Differ. 13 (2006) 798-815
    • (2006) Cell Death Differ. , vol.13 , pp. 798-815
    • Werts, C.1    Girardin, S.E.2    Philpott, D.J.3
  • 67
    • 34547911034 scopus 로고    scopus 로고
    • TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1
    • Zeng H., Ornatowska M., Joo M.S., and Sadikot R.T. TREM-1 expression in macrophages is regulated at transcriptional level by NF-kappaB and PU.1. Eur. J. Immunol. 37 (2007) 2300-2308
    • (2007) Eur. J. Immunol. , vol.37 , pp. 2300-2308
    • Zeng, H.1    Ornatowska, M.2    Joo, M.S.3    Sadikot, R.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.