Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis

Arthritis and Rheumatism

Volumn 60, Issue 6, 2009, Pages 1615-1623

  Murakami, Yousuke ^a   Akahoshi, Tohru ^b   Aoki, Naoko ^c   Toyomoto, Masayasu ^a   Miyasaka, Nobuyuki ^a   Kohsaka, Hitoshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c ASAHIKAWA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOVIRUS VECTOR; ANTIBODY; AXCALACZ; AXCATREM 1 IG; CD14 ANTIGEN; COLLAGEN; COLLAGEN ANTIBODY; COLLAGEN TYPE 2; FC RECEPTOR; LEUCYLGLUTAMINYLVALYLTHREONYLASPARTYLSERYLGLYCYLLEUCYLTYROSYLARGINYLCYSTEINYLVAL YLISOLEUCYLTYROSYLHISTIDYLPROLYLPROLINE; LIPOPOLYSACCHARIDE; LP 17; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE INHIBITOR; RECOMBINANT ADENOVIRUS VECTOR; THREONYLASPARTYLSERYLARGINYLCYSTEINYLVALYLISOLEUCYLGLYCYLLEUCYLTYROSYLHISTIDYLPR OLYLPROLYLLEUCYLGLUTAMINYLVALYLTYROSINE; TREM 1 ANTIBODY; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOSE RESPONSE; DRUG EFFICACY; DRUG TARGETING; FLOW CYTOMETRY; GENE; HUMAN; HUMAN TISSUE; INFLAMMATION; LACZ GENE; MACROPHAGE; MALE; MONOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SPLEEN CELL; SYNOVIOCYTE; SYNOVIUM; T LYMPHOCYTE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; CELLS, CULTURED; DINOPROSTONE; DISEASE MODELS, ANIMAL; HUMANS; IMMUNOGLOBULIN G; INFLAMMATION MEDIATORS; MACROPHAGES; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED DBA; PEPTIDES; RECEPTORS, IMMUNOLOGIC; SYNOVIAL MEMBRANE; UP-REGULATION;

EID: 66449085242     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.24554     Document Type: Article

References (45)

1. Bresnihan B. Pathogenesis of joint damage in rheumatoid arthritis. J Rheumatol 1999;26:717-719 (Pubitemid 29125598)
2. 2 receptors in the pathogenesis of rheumatoid arthritis. J Clin Invest 2002;110:651-658
3. McInnes IB, Leung BP, Field M, Wei XQ, Huang FP, Sturrock RD, et al. Production of nitric oxide in the synovial membrane of rheumatoid and osteoarthritis patients. J Exp Med 1996;184: 1519-1524 (Pubitemid 26354707)
4. Szekanecz Z, Koch AE. Macrophages and their products in rheumatoid arthritis. Curr Opin Rheumatol 2007;19:289-295
5. Bouchon A, Dietrich J, Colonna M. Inflammatory responses can be triggered by TREM-1, a novel receptor expressed on neutrophils and monocytes. J Immunol 2000;164:4991-4995 (Pubitemid 30305166)
6. Klesney-Tait J, Turnbull IR, Colonna M. The TREM receptor family and signal integration. Nat Immunol 2006;7:1266-1273 (Pubitemid 46111244)
7. Murakami Y, Akahoshi T, Hayashi I, Endo H, Kawai S, Inoue M, et al. Induction of triggering receptor expressed on myeloid cells 1 in murine resident peritoneal macrophages by monosodium urate monohydrate crystals. Arthritis Rheum 2006;54:455-462 (Pubitemid 43228619)
8. Bleharski JR, Kiessler V, Buonsanti C, Sieling PA, Stenger S, Colonna M, et al. A role for triggering receptor expressed on myeloid cells-1 in host defense during the early-induced and adaptive phases of the immune response. J Immunol 2003;170: 3812-3818 (Pubitemid 36359251)
9. Bouchon A, Facchetti F, Weigand MA, Colonna M. TREM-1 amplifies inflammation and is a crucial mediator of septic shock. Nature 2001;410:1103-1107 (Pubitemid 32391042)
10. Knapp S, Gibot S, de Vos A, Versteeg HH, Colonna M, van der Poll T. Expression patterns of surface and soluble triggering receptor expressed on myeloid cells-1 in human endotoxemia. J Immunol 2004;173:7131-7134 (Pubitemid 39628147)
11. Gibot S, Cravoisy A, Levy B, Bene MC, Faure G, Bollaert PE. Soluble triggering receptor expressed on myeloid cells and the diagnosis of pneumonia. N Engl J Med 2004;350:451-458 (Pubitemid 38133765)
12. Gibot S, Cravoisy A, Kolopp-Sarda MN, Bene MC, Faure G, Bollaert PE, et al. Time-course of sTREM (soluble triggering receptor expressed on myeloid cells)-1, procalcitonin, and C-reactive protein plasma concentrations during sepsis. Crit Care Med 2005;33:792-796 (Pubitemid 40504390)
13. Gibot S, Kolopp-Sarda MN, Bene MC, Bollaert PE, Lozniewski A, Mory F, et al. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis. J Exp Med 2004;200:1419-1426 (Pubitemid 39657289)
14. Schenk M, Bouchon A, Seibold F, Mueller C. TREM-1-expressing intestinal macrophages crucially amplify chronic inflammation in experimental colitis and inflammatory bowel diseases. J Clin Invest 2007;117:3097-3106 (Pubitemid 47529639)
15. Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 2007;117:514-521 (Pubitemid 46348505)
16. Harigai M, Koike R, Miyasaka N, for the Pneumocystis Pneumonia under Anti-Tumor Necrosis Factor Therapy (PAT) Study Group. Pneumocystis pneumonia associated with infliximab in Japan [letter]. N Engl J Med 2007;357:1874-1876.
17. Winthrop KL. Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor. Nat Clin Pract Rheumatol 2006;2:602-610 (Pubitemid 44650948)
18. Ogawa J, Harigai M, Akashi T, Nagasaka K, Suzuki F, Tominaga S, et al. Exacerbation of chronic active Epstein-Barr virus infection in a patient with rheumatoid arthritis receiving humanised anti-interleukin- 6 receptor monoclonal antibody. Ann Rheum Dis 2006;65:1667-1669 (Pubitemid 44799688)
19. Boren EJ, Cheema GS, Naguwa SM, Ansari AA, Gershwin ME. The emergence of progressive multifocal leukoencephalopathy (PML) in rheumatic diseases. J Autoimmun 2008;30:90-98
20. Murakami Y, Kohsaka H, Kitasato H, Akahoshi T. Lipopolysaccharide- induced up-regulation of triggering receptor expressed on myeloid cells-1 expression on macrophages is regulated by endogenous prostaglandin E2. J Immunol 2007;178:1144-1150 (Pubitemid 46095187)
21. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988;31:315-324
22. Nonomura Y, Nagasaka K, Hagiyama H, Sekine C, Nanki T, Tamamori-Adachi M, et al. Direct modulation of rheumatoid inflammatory mediator expression in retinoblastoma protein-dependent and -independent pathways by cyclin-dependent kinase 4/6. Arthritis Rheum 2006;54:2074-2083 (Pubitemid 44051063)
23. 2-EP2/EP4 signaling both mediate joint inflammation in mouse collagen-induced arthritis. J Exp Med 2006;203:325-335
24. Nochi H, Aoki N, Oikawa K, Yanai M, Takiyama Y, Atsuta Y, et al. Modulation of hepatic granulomatous responses by transgene expression of DAP12 or TREM-1-Ig molecules. Am J Pathol 2003;162:1191-1201 (Pubitemid 36350663)
25. Sekine C, Sugihara T, Miyake S, Hirai H, Yoshida M, Miyasaka N, et al. Successful treatment of animal models of rheumatoid arthritis with small-molecule cyclin-dependent kinase inhibitors. J Immunol 2008;180:1954-1961
26. Martin-Saavedra FM, Flores N, Dorado B, Eguiluz C, Bravo B, Garcia-Merino A, et al. Beta-interferon unbalances the peripheral T cell proinflammatory response in experimental autoimmune encephalomyelitis. Mol Immunol 2007;44:3597-3607 (Pubitemid 46754436)
27. Murakami Y, Akahoshi T, Hayashi I, Endo H, Hashimoto A, Kono S, et al. Inhibition of monosodium urate monohydrate crystal-induced acute inflammation by retrovirally transfected prostaglandin D synthase. Arthritis Rheum 2003;48:2931-2941 (Pubitemid 37280623)
28. Ohata J, Miura T, Johnson TA, Hori S, Ziegler SF, Kohsaka H. Enhanced efficacy of regulatory T cell transfer against increasing resistance, by elevated Foxp3 expression induced in arthritic murine hosts. Arthritis Rheum 2007;56:2947-2956 (Pubitemid 47502741)
29. Alexis N, Soukup J, Ghio A, Becker S. Sputum phagocytes from healthy individuals are functional and activated: a flow cytometric comparison with cells in bronchoalveolar lavage and peripheral blood. Clin Immunol 2000;97:21-32.
30. Ijima K, Murakami M, Okamoto H, Inobe M, Chikuma S, Saito I, et al. Successful gene therapy via intraarticular injection of adenovirus vector containing CTLA4IgG in a murine model of type II collagen-induced arthritis. Hum Gene Ther 2001;12: 1063-1077 (Pubitemid 32692422)
31. Radsak MP, Salih HR, Rammensee HG, Schild H. Triggering receptor expressed on myeloid cells-1 in neutrophil inflammatory responses: differential regulation of activation and survival. J Immunol 2004;172:4956-4963 (Pubitemid 38456421)
32. Inglis JJ, Notley CA, Essex D, Wilson AW, Feldmann M, Anand P, et al. Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade. Arthritis Rheum 2007;56:4015-4023 (Pubitemid 350262329)
33. Ochi T, Ohkubo Y, Mutoh S. Role of cyclooxygenase-2, but not cyclooxygenase-1, on type II collagen-induced arthritis in DBA/1J mice. Biochem Pharmacol 2003;66:1055-1060 (Pubitemid 37083602)
34. Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, Ogawa N, et al. Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis. Arthritis Rheum 2004;50:1457-1467 (Pubitemid 38608067)
35. Radstake TR, Roelofs MF, Jenniskens YM, Oppers-Walgreen B, van Riel PL, Barrera P, et al. Expression of Toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-γ. Arthritis Rheum 2004;50:3856-3865 (Pubitemid 39643932)
36. Hino K, Shiozawa S, Kuroki Y, Ishikawa H, Shiozawa K, Sekiguchi K, et al. EDA-containing fibronectin is synthesized from rheumatoid synovial fibroblast-like cells. Arthritis Rheum 1995;38:678-683
37. Okamura Y, Watari M, Jerud ES, Young DW, Ishizaka ST, Rose J, et al. The extra domain A of fibronectin activates Toll-like receptor 4. J Biol Chem 2001;276:10229-10233 (Pubitemid 37391934)
38. Smiley ST, King JA, Hancock WW. Fibrinogen stimulates macrophage chemokine secretion through Toll-like receptor 4. J Immunol 2001;167:2887-2894 (Pubitemid 32768923)
39. Wagner H. Toll meets bacterial CpG-DNA. Immunity 2001;14: 499-502. (Pubitemid 32520861)
40. Termeer C, Benedix F, Sleeman J, Fieber C, Voith U, Ahrens T, et al. Oligosaccharides of hyaluronan activate dendritic cells via Toll-like receptor 4. J Exp Med 2002;195:99-111. (Pubitemid 34074500)
41. Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, et al. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 2003;48:971-981 (Pubitemid 36418239)
42. Park JS, Svetkauskaite D, He Q, Kim JY, Strassheim D, Ishizaka A, et al. Involvement of Toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004;279:7370-7377 (Pubitemid 38294612)
43. Youssef P, Roth J, Frosch M, Costello P, FitzGerald O, Sorg C, et al. Expression of myeloid related proteins (MRP) 8 and 14 and the MRP8/14 heterodimer in rheumatoid arthritis synovial membrane. J Rheumatol 1999;26:2523-2528
44. Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, et al. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock. Nat Med 2007;13:1042-1049 (Pubitemid 47517513)
45. Sacre SM, Andreakos E, Kiriakidis S, Amjadi P, Lundberg A, Giddins G, et al. The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis. Am J Pathol 2007;170:518-525 (Pubitemid 47339389)