Misfolded SOD1 is not a primary component of sporadic ALS

Acta Neuropathologica

Volumn 134, Issue 1, 2017, Pages 97-111

  Da Cruz, Sandrine ^a   Bui, Anh ^a   Saberi, Shahram ^a   Lee, Sandra K ^a   Stauffer, Jennifer ^a   McAlonis Downes, Melissa ^a   Schulte, Derek ^a   Pizzo, Donald P ^a   Parone, Philippe A ^a,c   Cleveland, Don W ^a,b   Ravits, John ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Fate Therapeutics   (United States)

Author keywords

Amyotrophic lateral sclerosis (ALS); Human patients; Misfolding; Neurodegeneration; Neuropathology; Sporadic (SALS); Superoxide dismutase (SOD1)

Indexed keywords

ALANINE; COPPER ZINC SUPEROXIDE DISMUTASE; TISSUE EXTRACT; VALINE; SOD1 PROTEIN, HUMAN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN RETRIEVAL; ARTICLE; AUTOPSY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE DURATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNODETECTION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IMMUNOREACTIVITY; LIMIT OF DETECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MISFOLDING; PYRAMIDAL NERVE CELL; SPINAL CORD; ADULT; AGED; ANIMAL; BRAIN CORTEX; DISEASE MODEL; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROTEIN FOLDING; TRANSGENIC MOUSE; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MICE, TRANSGENIC; MIDDLE AGED; PROTEIN FOLDING; SPINAL CORD; SUPEROXIDE DISMUTASE-1; YOUNG ADULT;

EID: 85014027713     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-017-1688-8     Document Type: Article

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