Impaired extracellular secretion of mutant superoxide dismutase 1 associates with neurotoxicity in familial amyotrophic lateral sclerosis

Journal of Neuroscience

Volumn 25, Issue 1, 2005, Pages 108-117

  Turner, Bradley J ^a   Atkin, Julie D ^a   Farg, Manal A ^a   Da, Wei Zang ^a   Rembach, Alan ^a   Lopes, Elizabeth C ^a   Patch, Justin D ^a   Hill, Andrew F ^a   Cheema, Surindar S ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Amyotrophic lateral sclerosis; CSF; Neuronal inclusion; NSC 34 cell; Protein aggregation; Secretion; Superoxide dismutase 1; Transgenic rat

Indexed keywords

BREFELDIN A; COPPER ZINC SUPEROXIDE DISMUTASE; ENHANCED GREEN FLUORESCENT PROTEIN;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CELL INCLUSION; CELL LINE; CELL SECRETION; CELL STRAIN COS7; DISEASE COURSE; DRUG INFUSION; ENZYME RELEASE; FAMILIAL DISEASE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MOTONEURON; MOUSE; MUSCLE FIBRIL; NEUROTOXICITY; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSGENIC ANIMAL;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; DISEASE MODELS, ANIMAL; HUMANS; INCLUSION BODIES; MICE; MOTOR NEURONS; MOVEMENT; MUTATION; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT FUSION PROTEINS; SUPEROXIDE DISMUTASE;

EID: 12144249923     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.4253-04.2005     Document Type: Article

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