-
1
-
-
77951648486
-
From the metabolic syndrome to NAFLD or vice versa?
-
Vanni, E. et al. From the metabolic syndrome to NAFLD or vice versa? Dig Liver Dis 42, 320-330, doi:10. 1016/j. dld. 2010. 01. 016 (2010).
-
(2010)
Dig Liver Dis
, vol.42
, pp. 320-330
-
-
Vanni, E.1
-
2
-
-
77955839370
-
Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US
-
Ford, E. S., Li, C. & Zhao, G. Prevalence and correlates of metabolic syndrome based on a harmonious definition among adults in the US. J Diabetes 2, 180-193, doi:10. 1111/j. 1753-0407. 2010. 00078. x (2010).
-
(2010)
J Diabetes
, vol.2
, pp. 180-193
-
-
Ford, E.S.1
Li, C.2
Zhao, G.3
-
3
-
-
76049103016
-
Fatty liver and lipotoxicity
-
Trauner, M., Arrese, M. & Wagner, M. Fatty liver and lipotoxicity. Biochim Biophys Acta 1801, 299-310, doi:10. 1016/j. bbalip. 2009. 10. 007 (2010).
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 299-310
-
-
Trauner, M.1
Arrese, M.2
Wagner, M.3
-
4
-
-
84879557446
-
Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review
-
Taylor, K. W. et al. Evaluation of the Association between Persistent Organic Pollutants (POPs) and Diabetes in Epidemiological Studies: A National Toxicology Program Workshop Review. Environ Health Perspect 121, 774-783, doi:10. 1289/ehp. 1205502 (2013).
-
(2013)
Environ Health Perspect
, vol.121
, pp. 774-783
-
-
Taylor, K.W.1
-
5
-
-
79951805682
-
Endocrine disruptors: From endocrine to metabolic disruption
-
Casals-Casas, C. & Desvergne, B. Endocrine disruptors: from endocrine to metabolic disruption. Annu Rev Physiol 73, 135-162, doi:10. 1146/annurev-physiol-012110-142200 (2011).
-
(2011)
Annu Rev Physiol
, vol.73
, pp. 135-162
-
-
Casals-Casas, C.1
Desvergne, B.2
-
6
-
-
67349154088
-
Endocrine disrupters as obesogens
-
Grun, F. & Blumberg, B. Endocrine disrupters as obesogens. Mol Cell Endocrinol 304, 19-29, doi:10. 1016/j. mce. 2009. 02. 018 (2009).
-
(2009)
Mol Cell Endocrinol
, vol.304
, pp. 19-29
-
-
Grun, F.1
Blumberg, B.2
-
7
-
-
0038768712
-
Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals
-
Denison, M. S. & Nagy, S. R. Activation of the aryl hydrocarbon receptor by structurally diverse exogenous and endogenous chemicals. Annu Rev Pharmacol Toxicol 43, 309-334, doi:10. 1146/annurev. pharmtox. 43. 100901. 135828 (2003).
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 309-334
-
-
Denison, M.S.1
Nagy, S.R.2
-
8
-
-
0028987872
-
The aryl hydrocarbon receptor complex
-
Hankinson, O. The aryl hydrocarbon receptor complex. Annu Rev Pharmacol Toxicol 35, 307-340, doi:10. 1146/annurev. pa. 35. 040195. 001515 (1995).
-
(1995)
Annu Rev Pharmacol Toxicol
, vol.35
, pp. 307-340
-
-
Hankinson, O.1
-
9
-
-
84857378248
-
A novel nonconsensus xenobiotic response element capable of mediating aryl hydrocarbon receptordependent gene expression
-
Huang, G. & Elferink, C. J. A novel nonconsensus xenobiotic response element capable of mediating aryl hydrocarbon receptordependent gene expression. Mol Pharmacol 81, 338-347, doi:10. 1124/mol. 111. 075952 (2012).
-
(2012)
Mol Pharmacol
, vol.81
, pp. 338-347
-
-
Huang, G.1
Elferink, C.J.2
-
10
-
-
42949142113
-
The aryl hydrocarbon receptor complex and the control of gene expression
-
Beischlag, T. V., Luis Morales, J., Hollingshead, B. D. & Perdew, G. H. The aryl hydrocarbon receptor complex and the control of gene expression. Crit Rev Eukaryot Gene Expr 18, 207-250 (2008).
-
(2008)
Crit Rev Eukaryot Gene Expr
, vol.18
, pp. 207-250
-
-
Beischlag, T.V.1
Luis Morales, J.2
Hollingshead, B.D.3
Perdew, G.H.4
-
11
-
-
0024997614
-
Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: Environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs)
-
Safe, S. Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Crit Rev Toxicol 21, 51-88, doi:10. 3109/10408449009089873 (1990).
-
(1990)
Crit Rev Toxicol
, vol.21
, pp. 51-88
-
-
Safe, S.1
-
12
-
-
84155196846
-
Exactly the same but different: Promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor
-
Denison, M. S., Soshilov, A. A., He, G., DeGroot, D. E. & Zhao, B. Exactly the same but different: promiscuity and diversity in the molecular mechanisms of action of the aryl hydrocarbon (dioxin) receptor. Toxicol Sci 124, 1-22, doi:10. 1093/toxsci/kfr218 (2011).
-
(2011)
Toxicol Sci
, vol.124
, pp. 1-22
-
-
Denison, M.S.1
Soshilov, A.A.2
He, G.3
DeGroot, D.E.4
Zhao, B.5
-
13
-
-
20544460373
-
Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDDMediated hepatotoxicity
-
Boverhof, D. R. et al. Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDDMediated hepatotoxicity. Toxicol Sci 85, 1048-1063, doi:10. 1093/toxsci/kfi162 (2005).
-
(2005)
Toxicol Sci
, vol.85
, pp. 1048-1063
-
-
Boverhof, D.R.1
-
14
-
-
0016747226
-
Pathological-Changes in Liver of Mice Given 2, 3, 7, 8-Tetrachlorodibenzo-P-Dioxin
-
Jones, G. & Greig, J. B. Pathological-Changes in Liver of Mice Given 2, 3, 7, 8-Tetrachlorodibenzo-P-Dioxin. Experientia 31, 1315-1317, doi:10. 1007/Bf01945801 (1975).
-
(1975)
Experientia
, vol.31
, pp. 1315-1317
-
-
Jones, G.1
Greig, J.B.2
-
15
-
-
0030245635
-
Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity
-
Fernandez-Salguero, P. M., Hilbert, D. M., Rudikoff, S., Ward, J. M. & Gonzalez, F. J. Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity. Toxicol Appl Pharmacol 140, 173-179, doi:10. 1006/taap. 1996. 0210 (1996).
-
(1996)
Toxicol Appl Pharmacol
, vol.140
, pp. 173-179
-
-
Fernandez-Salguero, P.M.1
Hilbert, D.M.2
Rudikoff, S.3
Ward, J.M.4
Gonzalez, F.J.5
-
16
-
-
85013766988
-
Dose-dependent metabolic reprogramming and differential gene expression in TCDD-elicited hepatic fibrosis
-
Nault, R. et al. Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis. Toxicol Sci 154, 253-266, doi:10. 1093/toxsci/kfw163 (2016).
-
(2016)
Toxicol Sci
, vol.154
, pp. 253-266
-
-
Nault, R.1
-
17
-
-
84891294432
-
Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin
-
Pierre, S. et al. Aryl hydrocarbon receptor-dependent induction of liver fibrosis by dioxin. Toxicol Sci 137, 114-124, doi:10. 1093/ toxsci/kft236 (2014).
-
(2014)
Toxicol Sci
, vol.137
, pp. 114-124
-
-
Pierre, S.1
-
18
-
-
84891710536
-
Bile acid metabolism and signaling
-
Chiang, J. Y. Bile acid metabolism and signaling. Compr Physiol 3, 1191-1212, doi:10. 1002/cphy. c120023 (2013).
-
(2013)
Compr Physiol
, vol.3
, pp. 1191-1212
-
-
Chiang, J.Y.1
-
19
-
-
84952332338
-
Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules
-
Copple, B. L. & Li, T. Pharmacology of bile acid receptors: Evolution of bile acids from simple detergents to complex signaling molecules. Pharmacol Res 104, 9-21, doi:10. 1016/j. phrs. 2015. 12. 007 (2016).
-
(2016)
Pharmacol Res
, vol.104
, pp. 9-21
-
-
Copple, B.L.1
Li, T.2
-
20
-
-
65649124573
-
Bile-acid-induced cell injury and protection
-
Perez, M. J. & Briz, O. Bile-acid-induced cell injury and protection. World J Gastroenterol 15, 1677-1689 (2009).
-
(2009)
World J Gastroenterol
, vol.15
, pp. 1677-1689
-
-
Perez, M.J.1
Briz, O.2
-
21
-
-
78650793157
-
Bile acids induce inflammatory genes in hepatocytes: A novel mechanism of inflammation during obstructive cholestasis
-
Allen, K., Jaeschke, H. & Copple, B. L. Bile acids induce inflammatory genes in hepatocytes: a novel mechanism of inflammation during obstructive cholestasis. Am J Pathol 178, 175-186, doi:10. 1016/j. ajpath. 2010. 11. 026 (2011).
-
(2011)
Am J Pathol
, vol.178
, pp. 175-186
-
-
Allen, K.1
Jaeschke, H.2
Copple, B.L.3
-
22
-
-
0023708134
-
The acute toxicity of 2, 3, 4, 7, 8-pentachlorodibenzofuran (4PeCDF) in the male Fischer rat
-
Brewster, D. W., Uraih, L. C. & Birnbaum, L. S. The acute toxicity of 2, 3, 4, 7, 8-pentachlorodibenzofuran (4PeCDF) in the male Fischer rat. Fundam Appl Toxicol 11, 236-249 (1988).
-
(1988)
Fundam Appl Toxicol
, vol.11
, pp. 236-249
-
-
Brewster, D.W.1
Uraih, L.C.2
Birnbaum, L.S.3
-
23
-
-
0023940593
-
Dioxin-like effects observed in male rats following exposure to octachlorodibenzop-dioxin (OCDD) during a 13-week study
-
Couture, L. A., Elwell, M. R. & Birnbaum, L. S. Dioxin-like effects observed in male rats following exposure to octachlorodibenzop-dioxin (OCDD) during a 13-week study. Toxicol Appl Pharmacol 93, 31-46 (1988).
-
(1988)
Toxicol Appl Pharmacol
, vol.93
, pp. 31-46
-
-
Couture, L.A.1
Elwell, M.R.2
Birnbaum, L.S.3
-
24
-
-
0017693566
-
Effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on plasma disappearance and biliary excretion of foreign compounds in rats
-
Yang, K. H., Croft, W. A. & Peterson, R. E. Effects of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin on plasma disappearance and biliary excretion of foreign compounds in rats. Toxicol Appl Pharmacol 40, 485-496 (1977).
-
(1977)
Toxicol Appl Pharmacol
, vol.40
, pp. 485-496
-
-
Yang, K.H.1
Croft, W.A.2
Peterson, R.E.3
-
25
-
-
0016184508
-
Toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in C57B1/6 mice
-
Vos, J. G., Moore, J. A. & Zinkl, J. G. Toxicity of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) in C57B1/6 mice. Toxicol Appl Pharmacol 29, 229-241 (1974).
-
(1974)
Toxicol Appl Pharmacol
, vol.29
, pp. 229-241
-
-
Vos, J.G.1
Moore, J.A.2
Zinkl, J.G.3
-
26
-
-
23044461801
-
2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: A microarray study
-
Fletcher, N. et al. 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: a microarray study. Toxicol Appl Pharmacol 207, 1-24, doi:10. 1016/j. taap. 2004. 12. 003 (2005).
-
(2005)
Toxicol Appl Pharmacol
, vol.207
, pp. 1-24
-
-
Fletcher, N.1
-
27
-
-
78650522347
-
Aryl hydrocarbon receptor ligand 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice
-
Ozeki, J. et al. Aryl hydrocarbon receptor ligand 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice. Toxicology 280, 10-17, doi:10. 1016/j. tox. 2010. 11. 003 (2011).
-
(2011)
Toxicology
, vol.280
, pp. 10-17
-
-
Ozeki, J.1
-
28
-
-
41149144697
-
Novel potent and selective bile acid derivatives as TGR5 agonists: Biological screening, structure-activity relationships, and molecular modeling studies
-
Sato, H. et al. Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies. J Med Chem 51, 1831-1841, doi:10. 1021/jm7015864 (2008).
-
(2008)
J Med Chem
, vol.51
, pp. 1831-1841
-
-
Sato, H.1
-
29
-
-
84960224818
-
TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro
-
Reich, M. et al. TGR5 is essential for bile acid-dependent cholangiocyte proliferation in vivo and in vitro. Gut 65, 487-501, doi:10. 1136/gutjnl-2015-309458 (2016).
-
(2016)
Gut
, vol.65
, pp. 487-501
-
-
Reich, M.1
-
30
-
-
0024994258
-
Differential toxicity of 2, 3, 7, 8-tetrachlorodibenzo-pdioxin (TCDD) in C57BL/6J mice congenic at the Ah Locus
-
Birnbaum, L. S., McDonald, M. M., Blair, P. C., Clark, A. M. & Harris, M. W. Differential toxicity of 2, 3, 7, 8-tetrachlorodibenzo-pdioxin (TCDD) in C57BL/6J mice congenic at the Ah Locus. Fundam Appl Toxicol 15, 186-200 (1990).
-
(1990)
Fundam Appl Toxicol
, vol.15
, pp. 186-200
-
-
Birnbaum, L.S.1
McDonald, M.M.2
Blair, P.C.3
Clark, A.M.4
Harris, M.W.5
-
31
-
-
0018148562
-
The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and Guinea pigs
-
McConnell, E. E., Moore, J. A., Haseman, J. K. & Harris, M. W. The comparative toxicity of chlorinated dibenzo-p-dioxins in mice and guinea pigs. Toxicol Appl Pharmacol 44, 335-356 (1978).
-
(1978)
Toxicol Appl Pharmacol
, vol.44
, pp. 335-356
-
-
McConnell, E.E.1
Moore, J.A.2
Haseman, J.K.3
Harris, M.W.4
-
32
-
-
84952924611
-
2, 3, 7, 8-tetrachlorodibenzo-p-dioxin alters lipid metabolism and depletes immune cell populations in the jejunum of c57bl/6 mice
-
Fader, K. A. et al. 2, 3, 7, 8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice. Toxicol Sci 148, 567-580, doi:10. 1093/toxsci/kfv206 (2015).
-
(2015)
Toxicol Sci
, vol.148
, pp. 567-580
-
-
Fader, K.A.1
-
33
-
-
85013816220
-
Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBalpha/beta activation in aryl hydrocarbon receptor-elicited hepatotoxicity
-
Fader, K. A. et al. Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBalpha/beta activation in aryl hydrocarbon receptor-elicited hepatotoxicity. Toxicol Appl Pharmacol 321, 1-17, doi:10. 1016/j. taap. 2017. 02. 006 (2017).
-
(2017)
Toxicol Appl Pharmacol
, vol.321
, pp. 1-17
-
-
Fader, K.A.1
-
34
-
-
85018494909
-
Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin
-
Nault, R., Fader, K. A., Lydic, T. A. & Zacharewski, T. R. Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin. Chem Res Toxicol 30, 1060-1075, doi:10. 1021/ acs. chemrestox. 6b00430 (2017).
-
(2017)
Chem Res Toxicol
, vol.30
, pp. 1060-1075
-
-
Nault, R.1
Fader, K.A.2
Lydic, T.A.3
Zacharewski, T.R.4
-
35
-
-
0020562269
-
The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver
-
Botham, K. M. & Boyd, G. S. The metabolism of chenodeoxycholic acid to beta-muricholic acid in rat liver. Eur J Biochem 134, 191-196 (1983).
-
(1983)
Eur J Biochem
, vol.134
, pp. 191-196
-
-
Botham, K.M.1
Boyd, G.S.2
-
36
-
-
84960096867
-
Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2, 3, 7, 8-Tetrachlorodibenzo-p-Dioxin
-
Nault, R. et al. Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2, 3, 7, 8-Tetrachlorodibenzo-p-Dioxin. Toxicol Sci 149, 358-371, doi:10. 1093/toxsci/kfv245 (2016).
-
(2016)
Toxicol Sci
, vol.149
, pp. 358-371
-
-
Nault, R.1
-
37
-
-
84873342775
-
Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist
-
Sayin, S. I. et al. Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist. Cell Metab 17, 225-235, doi:10. 1016/j. cmet. 2013. 01. 003 (2013).
-
(2013)
Cell Metab
, vol.17
, pp. 225-235
-
-
Sayin, S.I.1
-
38
-
-
0018868656
-
Effects of bile salts on the plasma membranes of isolated rat hepatocytes
-
Billington, D., Evans, C. E., Godfrey, P. P. & Coleman, R. Effects of bile salts on the plasma membranes of isolated rat hepatocytes. Biochem J 188, 321-327 (1980).
-
(1980)
Biochem J
, vol.188
, pp. 321-327
-
-
Billington, D.1
Evans, C.E.2
Godfrey, P.P.3
Coleman, R.4
-
39
-
-
0015415107
-
Bile acids, liver injury, and liver disease
-
Palmer, R. H. Bile acids, liver injury, and liver disease. Arch Intern Med 130, 606-617 (1972).
-
(1972)
Arch Intern Med
, vol.130
, pp. 606-617
-
-
Palmer, R.H.1
-
40
-
-
0021739393
-
Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem
-
Hofmann, A. F. & Roda, A. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J Lipid Res 25, 1477-1489 (1984).
-
(1984)
J Lipid Res
, vol.25
, pp. 1477-1489
-
-
Hofmann, A.F.1
Roda, A.2
-
41
-
-
0024318186
-
Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions
-
Heuman, D. M. Quantitative estimation of the hydrophilic-hydrophobic balance of mixed bile salt solutions. J Lipid Res 30, 719-730 (1989).
-
(1989)
J Lipid Res
, vol.30
, pp. 719-730
-
-
Heuman, D.M.1
-
42
-
-
0033583336
-
6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes
-
Araya, Z. & Wikvall, K. 6alpha-hydroxylation of taurochenodeoxycholic acid and lithocholic acid by CYP3A4 in human liver microsomes. Biochim Biophys Acta 1438, 47-54 (1999).
-
(1999)
Biochim Biophys Acta
, vol.1438
, pp. 47-54
-
-
Araya, Z.1
Wikvall, K.2
-
43
-
-
0035853057
-
An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids
-
Xie, W. et al. An essential role for nuclear receptors SXR/PXR in detoxification of cholestatic bile acids. Proc Natl Acad Sci USA 98, 3375-3380, doi:10. 1073/pnas. 051014398 (2001).
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3375-3380
-
-
Xie, W.1
-
44
-
-
0036197121
-
Bile salt transporters
-
Meier, P. J. & Stieger, B. Bile salt transporters. Annu Rev Physiol 64, 635-661, doi:10. 1146/annurev. physiol. 64. 082201. 100300 (2002).
-
(2002)
Annu Rev Physiol
, vol.64
, pp. 635-661
-
-
Meier, P.J.1
Stieger, B.2
-
45
-
-
78751502413
-
Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice
-
Csanaky, I. L. et al. Organic anion-transporting polypeptide 1b2 (Oatp1b2) is important for the hepatic uptake of unconjugated bile acids: Studies in Oatp1b2-null mice. Hepatology 53, 272-281, doi:10. 1002/hep. 23984 (2011).
-
(2011)
Hepatology
, vol.53
, pp. 272-281
-
-
Csanaky, I.L.1
-
46
-
-
84903524994
-
Metabolism of cholesterol and bile acids by the gut microbiota
-
Gérard, P. Metabolism of Cholesterol and Bile Acids by the Gut Microbiota. Pathogens 3, 14-24, doi:10. 3390/pathogens3010014 (2014).
-
(2014)
Pathogens
, vol.3
, pp. 14-24
-
-
Gérard, P.1
-
47
-
-
84455192400
-
Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7alpha-dehydroxylating intestinal bacterium
-
Ridlon, J. M. & Hylemon, P. B. Identification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7alpha-dehydroxylating intestinal bacterium. J Lipid Res 53, 66-76, doi:10. 1194/jlr. M020313 (2012).
-
(2012)
J Lipid Res
, vol.53
, pp. 66-76
-
-
Ridlon, J.M.1
Hylemon, P.B.2
-
48
-
-
0037403187
-
Development and application of a polymerase chain reaction assay for the detection and enumeration of bile acid 7alpha-dehydroxylating bacteria in human feces
-
Wells, J. E., Williams, K. B., Whitehead, T. R., Heuman, D. M. & Hylemon, P. B. Development and application of a polymerase chain reaction assay for the detection and enumeration of bile acid 7alpha-dehydroxylating bacteria in human feces. Clin Chim Acta 331, 127-134 (2003).
-
(2003)
Clin Chim Acta
, vol.331
, pp. 127-134
-
-
Wells, J.E.1
Williams, K.B.2
Whitehead, T.R.3
Heuman, D.M.4
Hylemon, P.B.5
-
49
-
-
84879456755
-
Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans
-
Ou, J. et al. Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans. Am J Clin Nutr 98, 111-120, doi:10. 3945/ajcn. 112. 056689 (2013).
-
(2013)
Am J Clin Nutr
, vol.98
, pp. 111-120
-
-
Ou, J.1
-
50
-
-
84979690573
-
TCDD modulation of gut microbiome correlated with liver and immune toxicity in streptozotocin (STZ)-induced hyperglycemic mice
-
Lefever, D. E. et al. TCDD modulation of gut microbiome correlated with liver and immune toxicity in streptozotocin (STZ)-induced hyperglycemic mice. Toxicol Appl Pharmacol 304, 48-58, doi:10. 1016/j. taap. 2016. 05. 016 (2016).
-
(2016)
Toxicol Appl Pharmacol
, vol.304
, pp. 48-58
-
-
Lefever, D.E.1
-
51
-
-
84936159079
-
Persistent organic pollutants modify gut microbiota-host metabolic homeostasis in mice through aryl hydrocarbon receptor activation
-
Zhang, L. et al. Persistent Organic Pollutants Modify Gut Microbiota-Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Activation. Environ Health Perspect 123, 679-688, doi:10. 1289/ehp. 1409055 (2015).
-
(2015)
Environ Health Perspect
, vol.123
, pp. 679-688
-
-
Zhang, L.1
-
52
-
-
84946895884
-
Dioxin-produced alteration in the profiles of fecal and urinary metabolomes: a change in bile acids and its relevance to toxicity
-
Kakizuka, S. et al. Dioxin-Produced Alteration in the Profiles of Fecal and Urinary Metabolomes: A Change in Bile Acids and Its Relevance to Toxicity. Biol Pharm Bull 38, 1484-1495, doi:10. 1248/bpb. b15-00235 (2015).
-
(2015)
Biol Pharm Bull
, vol.38
, pp. 1484-1495
-
-
Kakizuka, S.1
-
53
-
-
84991053856
-
Intestinal crosstalk between bile acids and microbiota and its impact on host metabolism
-
Wahlstrom, A., Sayin, S. I., Marschall, H. U. & Backhed, F. Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism. Cell Metab 24, 41-50, doi:10. 1016/j. cmet. 2016. 05. 005 (2016).
-
(2016)
Cell Metab
, vol.24
, pp. 41-50
-
-
Wahlstrom, A.1
Sayin, S.I.2
Marschall, H.U.3
Backhed, F.4
-
54
-
-
84991113199
-
The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4
-
Gao, X. et al. The antiandrogen flutamide is a novel aryl hydrocarbon receptor ligand that disrupts bile acid homeostasis in mice through induction of Abcc4. Biochem Pharmacol, doi:10. 1016/j. bcp. 2016. 08. 021 (2016).
-
(2016)
Biochem Pharmacol
-
-
Gao, X.1
-
55
-
-
34147151302
-
Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis
-
Iwanaga, T., Nakakariya, M., Yabuuchi, H., Maeda, T. & Tamai, I. Involvement of bile salt export pump in flutamide-induced cholestatic hepatitis. Biol Pharm Bull 30, 739-744 (2007).
-
(2007)
Biol Pharm Bull
, vol.30
, pp. 739-744
-
-
Iwanaga, T.1
Nakakariya, M.2
Yabuuchi, H.3
Maeda, T.4
Tamai, I.5
-
56
-
-
0014287967
-
Effect of sodium taurolithocholate on bile flow and bile acid exeretion
-
Javitt, N. B. & Emerman, S. Effect of sodium taurolithocholate on bile flow and bile acid exeretion. J Clin Invest 47, 1002-1014, doi:10. 1172/JCI105790 (1968).
-
(1968)
J Clin Invest
, vol.47
, pp. 1002-1014
-
-
Javitt, N.B.1
Emerman, S.2
-
57
-
-
0038381474
-
Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets
-
Beuers, U. et al. Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets. J Biol Chem 278, 17810-17818, doi:10. 1074/jbc. M209898200 (2003).
-
(2003)
J Biol Chem
, vol.278
, pp. 17810-17818
-
-
Beuers, U.1
-
58
-
-
0032447116
-
The aryl hydrocarbon receptor: Studies using the AHR-null mice
-
Gonzalez, F. J. & Fernandez-Salguero, P. The aryl hydrocarbon receptor: studies using the AHR-null mice. Drug Metab Dispos 26, 1194-1198 (1998).
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 1194-1198
-
-
Gonzalez, F.J.1
Fernandez-Salguero, P.2
-
59
-
-
84872424975
-
TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice
-
Angrish, M. M., Dominici, C. Y. & Zacharewski, T. R. TCDD-elicited effects on liver, serum, and adipose lipid composition in C57BL/6 mice. Toxicol Sci 131, 108-115, doi:10. 1093/toxsci/kfs277 (2013).
-
(2013)
Toxicol Sci
, vol.131
, pp. 108-115
-
-
Angrish, M.M.1
Dominici, C.Y.2
Zacharewski, T.R.3
-
60
-
-
70349587834
-
2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: Identification and measurement of TCDD metabolites
-
Sorg, O. et al. 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) poisoning in Victor Yushchenko: identification and measurement of TCDD metabolites. Lancet 374, 1179-1185, doi:10. 1016/S0140-6736(09)60912-0 (2009).
-
(2009)
Lancet
, vol.374
, pp. 1179-1185
-
-
Sorg, O.1
-
61
-
-
0028336621
-
Determinants of TCDD half-life in veterans of operation ranch hand
-
Wolfe, W. H. et al. Determinants of TCDD half-life in veterans of operation ranch hand. J Toxicol Environ Health 41, 481-488, doi:10. 1080/15287399409531858 (1994).
-
(1994)
J Toxicol Environ Health
, vol.41
, pp. 481-488
-
-
Wolfe, W.H.1
-
62
-
-
0020556135
-
Distribution, excretion, and metabolism of 2, 3, 7, 8-tetrachlorodibenzo-pdioxin in C57BL/6J, DBA/2J, and B6D2F1/J mice
-
Gasiewicz, T. A., Geiger, L. E., Rucci, G. & Neal, R. A. Distribution, excretion, and metabolism of 2, 3, 7, 8-tetrachlorodibenzo-pdioxin in C57BL/6J, DBA/2J, and B6D2F1/J mice. Drug Metab Dispos 11, 397-403 (1983).
-
(1983)
Drug Metab Dispos
, vol.11
, pp. 397-403
-
-
Gasiewicz, T.A.1
Geiger, L.E.2
Rucci, G.3
Neal, R.A.4
-
63
-
-
0019272744
-
A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction
-
Everson, G. T., Braverman, D. Z., Johnson, M. L. & Kern, F. Jr. A critical evaluation of real-time ultrasonography for the study of gallbladder volume and contraction. Gastroenterology 79, 40-46 (1980).
-
(1980)
Gastroenterology
, vol.79
, pp. 40-46
-
-
Everson, G.T.1
Braverman, D.Z.2
Johnson, M.L.3
Kern, F.4
-
64
-
-
74149083804
-
Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice
-
Wang, H. H. et al. Effect of gallbladder hypomotility on cholesterol crystallization and growth in CCK-deficient mice. Biochim Biophys Acta 1801, 138-146, doi:10. 1016/j. bbalip. 2009. 10. 003 (2010).
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 138-146
-
-
Wang, H.H.1
-
65
-
-
77049107075
-
PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: Comparative toxicogenomic effects of dioxin and non-dioxin-like ligands
-
Kopec, A. K. et al. PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: comparative toxicogenomic effects of dioxin and non-dioxin-like ligands. Toxicol Appl Pharmacol 243, 359-371, doi:10. 1016/j. taap. 2009. 12. 003 (2010).
-
(2010)
Toxicol Appl Pharmacol
, vol.243
, pp. 359-371
-
-
Kopec, A.K.1
-
66
-
-
84930830657
-
Development of a computational high-throughput tool for the quantitative examination of dose-dependent histological features
-
Nault, R., Colbry, D., Brandenberger, C., Harkema, J. R. & Zacharewski, T. R. Development of a computational high-throughput tool for the quantitative examination of dose-dependent histological features. Toxicol Pathol 43, 366-375, doi:10. 1177/0192623314544379 (2015).
-
(2015)
Toxicol Pathol
, vol.43
, pp. 366-375
-
-
Nault, R.1
Colbry, D.2
Brandenberger, C.3
Harkema, J.R.4
Zacharewski, T.R.5
-
67
-
-
84930656041
-
RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice
-
Nault, R., Fader, K. A. & Zacharewski, T. RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice. BMC Genomics 16, 373, doi:10. 1186/s12864-015-1527-z (2015).
-
(2015)
BMC Genomics
, vol.16
, pp. 373
-
-
Nault, R.1
Fader, K.A.2
Zacharewski, T.3
-
68
-
-
47849100473
-
Automated quantitative dose-response modeling and point of departure determination for large toxicogenomic and high-throughput screening data sets
-
Burgoon, L. D. & Zacharewski, T. R. Automated quantitative dose-response modeling and point of departure determination for large toxicogenomic and high-throughput screening data sets. Toxicol Sci 104, 412-418, doi:10. 1093/toxsci/kfn083 (2008).
-
(2008)
Toxicol Sci
, vol.104
, pp. 412-418
-
-
Burgoon, L.D.1
Zacharewski, T.R.2
-
69
-
-
38149075215
-
BMDExpress: A software tool for the benchmark dose analyses of genomic data
-
Yang, L., Allen, B. C. & Thomas, R. S. BMDExpress: a software tool for the benchmark dose analyses of genomic data. BMC Genomics 8, 387, doi:10. 1186/1471-2164-8-387 (2007).
-
(2007)
BMC Genomics
, vol.8
, pp. 387
-
-
Yang, L.1
Allen, B.C.2
Thomas, R.S.3
-
70
-
-
84869386849
-
High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq
-
Lo, R. & Matthews, J. High-resolution genome-wide mapping of AHR and ARNT binding sites by ChIP-Seq. Toxicol Sci 130, 349-361, doi:10. 1093/toxsci/kfs253 (2012).
-
(2012)
Toxicol Sci
, vol.130
, pp. 349-361
-
-
Lo, R.1
Matthews, J.2
-
71
-
-
55749094855
-
An integrated software system for analyzing ChIP-chip and ChIP-seq data
-
Ji, H. et al. An integrated software system for analyzing ChIP-chip and ChIP-seq data. Nat Biotechnol 26, 1293-1300, doi:10. 1038/ nbt. 1505 (2008).
-
(2008)
Nat Biotechnol
, vol.26
, pp. 1293-1300
-
-
Ji, H.1
-
72
-
-
84917686843
-
A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids
-
John, C. et al. A liquid chromatography-tandem mass spectrometry-based method for the simultaneous determination of hydroxy sterols and bile acids. J Chromatogr A 1371, 184-195, doi:10. 1016/j. chroma. 2014. 10. 064 (2014).
-
(2014)
J Chromatogr A
, vol.1371
, pp. 184-195
-
-
John, C.1
-
73
-
-
79952749979
-
Systemic gut microbial modulation of bile acid metabolism in host tissue compartments
-
Swann, J. R. et al. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proc Natl Acad Sci USA 108(Suppl 1), 4523-4530, doi:10. 1073/pnas. 1006734107 (2011).
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 4523-4530
-
-
Swann, J.R.1
-
74
-
-
84904984321
-
A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipids
-
Lydic, T. A., Busik, J. V. & Reid, G. E. A monophasic extraction strategy for the simultaneous lipidome analysis of polar and nonpolar retina lipids. J Lipid Res 55, 1797-1809, doi:10. 1194/jlr. D050302 (2014).
-
(2014)
J Lipid Res
, vol.55
, pp. 1797-1809
-
-
Lydic, T.A.1
Busik, J.V.2
Reid, G.E.3
-
75
-
-
78649695759
-
Metabolomic analysis and visualization engine for LC-MS data
-
Melamud, E., Vastag, L. & Rabinowitz, J. D. Metabolomic analysis and visualization engine for LC-MS data. Anal Chem 82, 9818-9826, doi:10. 1021/ac1021166 (2010).
-
(2010)
Anal Chem
, vol.82
, pp. 9818-9826
-
-
Melamud, E.1
Vastag, L.2
Rabinowitz, J.D.3
-
76
-
-
33845581062
-
Software tools for analysis of mass spectrometric lipidome data
-
Haimi, P., Uphoff, A., Hermansson, M. & Somerharju, P. Software tools for analysis of mass spectrometric lipidome data. Anal Chem 78, 8324-8331, doi:10. 1021/ac061390w (2006).
-
(2006)
Anal Chem
, vol.78
, pp. 8324-8331
-
-
Haimi, P.1
Uphoff, A.2
Hermansson, M.3
Somerharju, P.4
-
77
-
-
54949129419
-
ProteoWizard: Open source software for rapid proteomics tools development
-
Kessner, D., Chambers, M., Burke, R., Agus, D. & Mallick, P. ProteoWizard: open source software for rapid proteomics tools development. Bioinformatics 24, 2534-2536, doi:10. 1093/bioinformatics/btn323 (2008).
-
(2008)
Bioinformatics
, vol.24
, pp. 2534-2536
-
-
Kessner, D.1
Chambers, M.2
Burke, R.3
Agus, D.4
Mallick, P.5
-
78
-
-
33749186777
-
Alterations in intestinal permeability
-
Arrieta, M. C., Bistritz, L. & Meddings, J. B. Alterations in intestinal permeability. Gut 55, 1512-1520, doi:10. 1136/gut. 2005. 085373 (2006).
-
(2006)
Gut
, vol.55
, pp. 1512-1520
-
-
Arrieta, M.C.1
Bistritz, L.2
Meddings, J.B.3
-
79
-
-
58149333594
-
The measurement and clinical significance of intestinal permeability
-
Teshima, C. W. & Meddings, J. B. The measurement and clinical significance of intestinal permeability. Curr Gastroenterol Rep 10, 443-449 (2008).
-
(2008)
Curr Gastroenterol Rep
, vol.10
, pp. 443-449
-
-
Teshima, C.W.1
Meddings, J.B.2
-
80
-
-
84885391639
-
FunGene: The functional gene pipeline and repository
-
Fish, J. A. et al. FunGene: the functional gene pipeline and repository. Front Microbiol 4, 291, doi:10. 3389/fmicb. 2013. 00291 (2013).
-
(2013)
Front Microbiol
, vol.4
, pp. 291
-
-
Fish, J.A.1
-
81
-
-
0027460328
-
Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA
-
Muyzer, G., de Waal, E. C. & Uitterlinden, A. G. Profiling of complex microbial populations by denaturing gradient gel electrophoresis analysis of polymerase chain reaction-amplified genes coding for 16S rRNA. Appl Environ Microbiol 59, 695-700 (1993).
-
(1993)
Appl Environ Microbiol
, vol.59
, pp. 695-700
-
-
Muyzer, G.1
De Waal, E.C.2
Uitterlinden, A.G.3
|