A novel nonconsensus xenobiotic response element capable of mediating aryl hydrocarbon receptor-dependent gene expression

Molecular Pharmacology

Volumn 81, Issue 3, 2012, Pages 338-347

  Huang, Gengming ^a   Elferink, Cornelis J ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1BETA; PLASMINOGEN ACTIVATOR INHIBITOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; GENE EXPRESSION; GENE TARGETING; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN FUNCTION; RNA INTERFERENCE; XENOBIOTIC METABOLISM;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATIN IMMUNOPRECIPITATION; DNA PRIMERS; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; MICE; MICE, INBRED C57BL; PLASMINOGEN ACTIVATOR INHIBITOR 1; POLYMERASE CHAIN REACTION; PROMOTER REGIONS, GENETIC; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

EID: 84857378248     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.111.075952     Document Type: Article

References (44)

1. Ahn YT, Chua MS, Whitlock JP Jr, Shin YC, Song WH, Kim Y, Eom CY, and An WG (2010) Rodent-specific hypoxia response elements enhance PAI-1 expression through HIF-1 or HIF-2 in mouse hepatoma cells. Int J Oncol 37:1627-1638.
2. Al-Nedawi KN, Czyz M, Bednarek R, Szemraj J, Swiatkowska M, Cierniewska- Cieslak A, Wyczolkowska J, and Cierniewski CS (2004) Thymosin beta 4 induces the synthesis of plasminogen activator inhibitor 1 in cultured endothelial cells and increases its extracellular expression. Blood 103:1319-1324. (Pubitemid 38168643)
3. Boverhof DR, Burgoon LD, Tashiro C, Chittim B, Harkema JR, Jump DB, and Zacharewski TR (2005) Temporal and dose-dependent hepatic gene expression patterns in mice provide new insights into TCDD-mediated hepatotoxicity. Toxicol Sci 85:1048-1063. (Pubitemid 40846879)
4. Chen YQ, Su M, Walia RR, Hao Q, Covington JW, and Vaughan DE (1998) Sp1 sites mediate activation of the plasminogen activator inhibitor-1 promoter by glucose in vascular smooth muscle cells. J Biol Chem 273:8225-8231. (Pubitemid 28168879)
5. Durand MK, Bødker JS, Christensen A, Dupont DM, Hansen M, Jensen JK, Kjelgaard S, Mathiasen L, Pedersen KE, Skeldal S, et al. (2004) Plasminogen activator inhibitor-I and tumour growth, invasion, and metastasis. Thromb Haemost 91: 438-449. (Pubitemid 38396865)
6. Elferink CJ, Ge NL, and Levine A (2001) Maximal aryl hydrocarbon receptor activity depends on an interaction with the retinoblastoma protein. Mol Pharmacol 59: 664-673. (Pubitemid 32273994)
7. Frueh FW, Hayashibara KC, Brown PO, and Whitlock JP Jr (2001) Use of cDNA microarrays to analyze dioxin-induced changes in human liver gene expression. Toxicol Lett 122:189-203. (Pubitemid 32727282)
8. Ge NL and Elferink CJ (1998) A direct interaction between the aryl hydrocarbon receptor and retinoblastoma protein. Linking dioxin signaling to the cell cycle. J Biol Chem 273:22708-22713.
9. Gu YZ, Hogenesch JB, and Bradfield CA (2000) The PAS superfamily: sensors of environmental and developmental signals. Annu Rev Pharmacol Toxicol 40:519-561. (Pubitemid 30340692)
10. Guo B, Inoki K, Isono M, Mori H, Kanasaki K, Sugimoto T, Akiba S, Sato T, Yang B, Kikkawa R, et al. (2005) MAPK/AP-1-dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells. Kidney Int 68:972-984. (Pubitemid 43246414)
11. He W, Tan R, Dai C, Li Y, Wang D, Hao S, Kahn M, and Liu Y (2010) Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/ beta-catenin signaling. J Biol Chem 285:24665-24675.
12. Huang G and Elferink CJ (2005) Multiple mechanisms are involved in Ah receptormediated cell cycle arrest. Mol Pharmacol 67:88-96. (Pubitemid 40069969)
13. Imagawa S, Fujii S, Dong J, Furumoto T, Kaneko T, Zaman T, Satoh Y, Tsutsui H, and Sobel BE (2006) Hepatocyte growth factor regulates E box-dependent plasminogen activator inhibitor type 1 gene expression in HepG2 liver cells. Arterioscler Thromb Vasc Biol 26:2407-2413. (Pubitemid 44465741)
14. Irigoyen JP, Muñoz-Cánoves P, Montero L, Koziczak M, and Nagamine Y (1999) The plasminogen activator system: biology and regulation. Cell Mol Life Sci 56:104-132. (Pubitemid 29471930)
15. Laird PW, Zijderveld A, Linders K, Rudnicki MA, Jaenisch R, and Berns A (1991) Simplified mammalian DNA isolation procedure. Nucleic Acids Res 19:4293.
16. Lees MJ and Whitelaw ML (1999) Multiple roles of ligand in transforming the dioxin receptor to an active basic helix-loop-helix/PAS transcription factor complex with the nuclear protein Arnt. Mol Cell Biol 19:5811-5822. (Pubitemid 29339935)
17. Levine-Fridman A, Chen L, and Elferink CJ (2004) Cytochrome P4501A1 promotes G1 phase cell cycle progression by controlling aryl hydrocarbon receptor activity. Mol Pharmacol 65:461-469. (Pubitemid 38134275)
18. Liu Q, Möller U, Flügel D, and Kietzmann T (2004) Induction of plasminogen activator inhibitor I gene expression by intracellular calcium via hypoxia-inducible factor-1. Blood 104:3993-4001. (Pubitemid 39620149)
19. Maemura K, de la Monte SM, Chin MT, Layne MD, Hsieh CM, Yet SF, Perrella MA, and Lee ME (2000) CLIF, a novel cycle-like factor, regulates the circadian oscillation of plasminogen activator inhibitor-1 gene expression. J Biol Chem 275:36847-36851. (Pubitemid 32002096)
20. Marlowe JL, Knudsen ES, Schwemberger S, and Puga A (2004) The aryl hydrocarbon receptor displaces p300 from E2F-dependent promoters and represses S phase-specific gene expression. J Biol Chem 279:29013-29022. (Pubitemid 38915771)
21. Michalopoulos GK and DeFrances MC (1997) Liver regeneration. Science 276:60-66.
22. Miller AG, Israel D, and Whitlock JP Jr (1983) Biochemical and genetic analysis of variant mouse hepatoma cells defective in the induction of benzo(a)pyrenemetabolizing enzyme activity. J Biol Chem 258:3523-3527. (Pubitemid 13055767)
23. Mitchell KA, Lockhart CA, Huang G, and Elferink CJ (2006) Sustained aryl hydrocarbon receptor activity attenuates liver regeneration. Mol Pharmacol 70:163-170.
24. Nguyen TT, Cho K, Stratton SA, and Barton MC (2005) Transcription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene. Mol Cell Biol 25:2147-2157. (Pubitemid 40354615)
25. Nukaya M, Walisser JA, Moran SM, Kennedy GD, and Bradfield CA (2010) Aryl hydrocarbon receptor nuclear translocator in hepatocytes is required for aryl hydrocarbon receptor-mediated adaptive and toxic responses in liver. Toxicol Sci 118:554-563.
26. Ohtake F, Takeyama K, Matsumoto T, Kitagawa H, Yamamoto Y, Nohara K, Tohyama C, Krust A, Mimura J, Chambon P, et al. (2003) Modulation of oestrogen receptor signalling by association with the activated dioxin receptor. Nature 423:545-550. (Pubitemid 36648579)
27. Park KT, Mitchell KA, Huang G, and Elferink CJ.-T., Mitchell K, Huang G, and Elferink CJ (2005) The aryl hydrocarbon receptor predisposes hepatocytes to Fas-mediated apoptosis. Mol Pharmacol 67:612-622. (Pubitemid 40365308)
28. Parra M, Jardí M, Koziczak M, Nagamine Y, and Muñoz- Cánoves P (2001) p53 phosphorylation at serine 15 is required for transcriptional induction of the plasminogen activator inhibitor-1 (PAI-1) gene by the alkylating agent N-methyl-N′- nitro-N-nitrosoguanidine. J Biol Chem 276:36303-36310.
29. Poland A and Knutson JC (1982) 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu Rev Pharmacol Toxicol 22:517-554.
30. Puga A, Maier A, and Medvedovic M (2000a) The transcriptional signature of dioxin in human hepatoma HepG2 cells. Biochem Pharmacol 60:1129-1142.
31. Puga A, Barnes SJ, Dalton TP, Chang C, Knudsen ES, and Maier MA (2000b) Aromatic hydrocarbon receptor interaction with the retinoblastoma protein potentiates repression of E2F-dependent transcription and cell cycle arrest. J Biol Chem 275:2943-2950. (Pubitemid 30082071)
32. Sartor MA, Schnekenburger M, Marlowe JL, Reichard JF, Wang Y, Fan Y, Ma C, Karyala S, Halbleib D, Liu X, et al. (2009) Genomewide analysis of aryl hydrocarbon receptor binding targets reveals an extensive array of gene clusters that control morphogenetic and developmental programs. Environ Health Perspect 117:1139-1146.
33. Schoenhard JA, Smith LH, Painter CA, Eren M, Johnson CH, and Vaughan DE (2003) Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2. J Mol Cell Cardiol 35:473-481. (Pubitemid 36539453)
34. Schwartz ML and Schlaepfer WW (1996) Neuronal promoter analysis by in vitro transcription using nuclear extracts from rat brain. Methods 10:320-327. (Pubitemid 26391931)
35. Shen ES, Elferink CJ, and Whitlock JP Jr (1991) Use of gel retardation to analyze protein-DNA interactions upstream of CYP1A1 gene. Methods Enzymol 206:403-408.
36. Sogawa K, Numayama-Tsuruta K, Takahashi T, Matsushita N, Miura C, Nikawa J, Gotoh O, Kikuchi Y, and Fujii-Kuriyama Y (2004) A novel induction mechanism of the rat CYP1A2 gene mediated by Ah receptor-Arnt heterodimer. Biochem Biophys Res Commun 318:746-755. (Pubitemid 38624218)
37. Son DS and Rozman KK (2002) 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces plasminogen activator inhibitor-1 through an aryl hydrocarbon receptor-mediated pathway in mouse hepatoma cell lines. Arch Toxicol 76:404-413.
38. Tijet N, Boutros PC, Moffat ID, Okey AB, Tuomisto J, and Pohjanvirta R (2006) Aryl hydrocarbon receptor regulates distinct dioxin-dependent and dioxin-independent gene batteries. Mol Pharmacol 69:140-153. (Pubitemid 43048901)
39. Vogel CF, Sciullo E, Li W, Wong P, Lazennec G, and Matsumura F (2007) RelB, a new partner of aryl hydrocarbon receptor-mediated transcription. Mol Endocrinol 21:2941-2955. (Pubitemid 350223506)
40. Vulin AI and Stanley FM (2004) Oxidative stress activates the plasminogen activator inhibitor type 1 (PAI-1) promoter through an AP-1 response element and cooperates with insulin for additive effects on PAI-1 transcription. J Biol Chem 279: 25172-25178. (Pubitemid 38756767)
41. Walisser JA, Glover E, Pande K, Liss AL, and Bradfield CA (2005) Aryl hydrocarbon receptor-dependent liver development and hepatotoxicity are mediated by different cell types. Proc Natl Acad Sci USA 102:17858-17863. (Pubitemid 41803587)
42. Weiss C, Kolluri SK, Kiefer F, and Göttlicher M (1996) Complementation of Ah receptor deficiency in hepatoma cells: negative feedback regulation and cell cycle control by the Ah receptor. Exp Cell Res 226:154-163. (Pubitemid 26238939)
43. White LA, Bruzdzinski C, Kutz SM, Gelehrter TD, and Higgins PJ (2000) Growth state-dependent binding of USF-1 to a proximal promoter E box element in the rat plasminogen activator inhibitor type 1 gene. Exp Cell Res 260:127-135.
44. Wyrzykowska P, Stalińska K, Wawro M, Kochan J, and Kasza A (2010) Epidermal growth factor regulates PAI-1 expression via activation of the transcription factor Elk-1. Biochim Biophys Acta 1799:616-621.