2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters the mRNA expression of critical genes associated with cholesterol metabolism, bile acid biosynthesis, and bile transport in rat liver: A microarray study

Toxicology and Applied Pharmacology

Volumn 207, Issue 1, 2005, Pages 1-24

  Fletcher, Nick ^a   Wahlström, David ^a   Lundberg, Rebecca ^a   Nilsson, Charlotte B ^b   Nilsson, Kerstin C ^b   Stockling, Kenneth ^b   Hellmold, Heike ^b   Håkansson, Helen ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Bile acid; Cholesterol metabolism; Rat liver

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; CARRIER PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYCLIN D1; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 ISOENZYME; CYTOSKELETON PROTEIN; FARNESYL X RECEPTOR; GLUCURONOSYLTRANSFERASE; GLUCURONOSYLTRANSFERASE 1A6; GLUCURONOSYLTRANSFERASE 1A7; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; LIVER ENZYME; MEMBRANE PROTEIN; MESSENGER RNA; METALLOTHIONEIN I; PROTEIN NTCP; PROTEIN SLC21A5; RECEPTOR; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOSYNTHESIS; CARBOHYDRATE METABOLISM; CARBON METABOLISM; CELL ADHESION; CELL CYCLE; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DNA DAMAGE; EXPOSURE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE INDUCTION; GENE REPRESSION; GENETIC TRANSCRIPTION; LIPID METABOLISM; LIVER; LIVER TOXICITY; NITROGEN METABOLISM; NONHUMAN; RAT; RECEPTOR BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STRESS; TOXICOKINETICS;

ANIMALS; BILE; BILE ACIDS AND SALTS; CARBOHYDRATE METABOLISM; CHOLESTEROL; GENE EXPRESSION PROFILING; KETONE BODIES; LIPIDS; LIVER; MALE; METABOLIC DETOXICATION, DRUG; NITROGEN; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN;

EID: 23044461801     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.taap.2004.12.003     Document Type: Article

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