PCB153-elicited hepatic responses in the immature, ovariectomized C57BL/6 mice: Comparative toxicogenomic effects of dioxin and non-dioxin-like ligands

Toxicology and Applied Pharmacology

Volumn 243, Issue 3, 2010, Pages 359-371

  Kopec, Anna K ^a,b   Burgoon, Lyle D ^a,b   Ibrahim Aibo, Daher ^b   Mets, Bryan D ^a,b   Tashiro, Colleen ^c   Potter, Dave ^c   Sharratt, Bonnie ^c   Harkema, Jack R ^b   Zacharewski, Timothy R ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c Research Division   (Canada)

Author keywords

Liver; Microarray; Mouse; PCB153; TCDD

Indexed keywords

2,2',4,4',5,5' HEXACHLOROBIPHENYL; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ACYL COA SYNTHETASE LONG CHAIN FAMILY MEMBER 3; AROMATIC HYDROCARBON RECEPTOR; ATP BINDING CASSETTE SUBFAMILY C MEMBER 3; CARBOXYLESTERASE; CONSTITUTIVE ANDROSTANE RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B; CYTOCHROME P450 2B10; CYTOCHROME P450 2C55; CYTOCHROME P450 3A11; ELOVL FAMILY MEMBER 5; GENE PRODUCT; GLUTATHIONE TRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; INSULIN INDUCED GENE 2; PREGNANE X RECEPTOR; PROTEIN MAD1; SESAME SEED OIL; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; ZW10 INTERACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; C57BL 6 MOUSE; CELL VACUOLE; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; HIGH RESOLUTION GAS CHROMATOGRAPHY; HISTOPATHOLOGY; LIPID LIVER LEVEL; LIVER HISTOLOGY; LIVER HYPERTROPHY; LIVER NECROSIS; LIVER WEIGHT; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; MOUSE; NONHUMAN; TISSUE MICROARRAY; TOXICOGENETICS;

ANIMALS; BODY WEIGHT; DIOXINS; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIGANDS; LIVER; MICE; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SIZE; OVARIECTOMY; POLYCHLORINATED BIPHENYLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; TETRACHLORODIBENZODIOXIN; TISSUE FIXATION; TOXICOGENETICS; TRIGLYCERIDES;

ANIMALIA; MUS; SESAMUM INDICUM;

EID: 77049107075     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.12.003     Document Type: Article

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