Development of a Computational High-Throughput Tool for the Quantitative Examination of Dose-Dependent Histological Features

Toxicologic Pathology

Volumn 43, Issue 3, 2015, Pages 366-375

  Nault, Rance ^a,b   Colbry, Dirk ^b   Brandenberger, Christina ^c   Harkema, Jack R ^b   Zacharewski, Timothy R ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

bioinformatics; hepatic; high throughput; histopathology; morphometry; quantitative; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; COLLAGEN; SESAME SEED OIL; AZO COMPOUND; COLORING AGENT; OIL RED O; POLLUTANT; POLYCHLORINATED DIBENZODIOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOINFORMATICS; CELL VACUOLE; CONTROLLED STUDY; DOSE RESPONSE; FATTY LIVER; FEMALE; HIGH THROUGHPUT SCREENING; IMAGE ANALYSIS; LIVER FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUALITY CONTROL; QUANTITATIVE ANALYSIS; QUANTITATIVE HISTOLOGICAL ANALYSIS TOOL; STAINING; TISSUE SECTION; VALIDATION STUDY; ANIMAL; BIOLOGY; C57BL MOUSE; CHEMICALLY INDUCED; FIBROSIS; HISTOLOGY; METABOLISM; PATHOLOGY; POLLUTANT; PROCEDURES; TOXICITY; TOXICOLOGY;

MUS; SESAMUM INDICUM;

ANIMALS; AZO COMPOUNDS; COLLAGEN; COLORING AGENTS; COMPUTATIONAL BIOLOGY; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FATTY LIVER; FEMALE; FIBROSIS; HIGH-THROUGHPUT SCREENING ASSAYS; HISTOLOGICAL TECHNIQUES; MICE; MICE, INBRED C57BL; POLYCHLORINATED DIBENZODIOXINS; TOXICOLOGY; VACUOLES;

EID: 84930830657     PISSN: 01926233     EISSN: 15331601     Source Type: Journal    
DOI: 10.1177/0192623314544379     Document Type: Article

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