Aryl hydrocarbon receptor ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin enhances liver damage in bile duct-ligated mice

Toxicology

Volumn 280, Issue 1-2, 2011, Pages 10-17

  Ozeki, Jun ^a   Uno, Shigeyuki ^a   Ogura, Michitaka ^a   Choi, Mihwa ^a   Maeda, Tetsuyo ^a   Sakurai, Kenichi ^a   Matsuo, Sadanori ^a   Amano, Sadao ^a   Nebert, Daniel W ^b   Makishima, Makoto ^a  

^a NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

Aryl hydrocarbon receptor; Bile duct ligation; Cholestasis; Hepatotoxicity; TCDD; Tumor necrosis factor

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; AMINOTRANSFERASE; AROMATIC HYDROCARBON RECEPTOR; ASPARTATE AMINOTRANSFERASE; BILE ACID; BILIRUBIN; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; GAMMA GLUTAMYLTRANSFERASE; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BILE ACID SYNTHESIS; BILE DUCT LIGATION; BILIRUBIN BLOOD LEVEL; CHOLESTASIS; CONTROLLED STUDY; ENZYME ACTIVATION; GENE EXPRESSION; HISTOLOGY; LIVER INJURY; LIVER LEVEL; LIVER NECROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SHAM PROCEDURE;

ANIMALS; BILE ACIDS AND SALTS; BILE DUCTS; CHOLESTASIS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; CYTOKINES; HEPATOCYTES; LIGATION; LIVER; MALE; MICE; MICE, INBRED C57BL; NECROSIS; RECEPTORS, ARYL HYDROCARBON; TETRACHLORODIBENZODIOXIN;

MUS;

EID: 78650522347     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.11.003     Document Type: Article

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