-
1
-
-
84883681998
-
Natural and induced T regulatory cells in cancer
-
Adeegbe, D.O., Nishikawa, H., Natural and induced T regulatory cells in cancer. Frontiers in Immunology, 4, 2013, 190.
-
(2013)
Frontiers in Immunology
, vol.4
, pp. 190
-
-
Adeegbe, D.O.1
Nishikawa, H.2
-
2
-
-
0033521543
-
DNA vaccination: Transfection and activation of dendritic cells as key events for immunity
-
Akbari, O., Panjwani, N., Garcia, S., Tascon, R., Lowrie, D., Stockinger, B., DNA vaccination: Transfection and activation of dendritic cells as key events for immunity. The Journal of Experimental Medicine 189 (1999), 169–178.
-
(1999)
The Journal of Experimental Medicine
, vol.189
, pp. 169-178
-
-
Akbari, O.1
Panjwani, N.2
Garcia, S.3
Tascon, R.4
Lowrie, D.5
Stockinger, B.6
-
3
-
-
77951734602
-
In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice
-
Akins, E.J., Moore, M.L., Tang, S., Willingham, M.C., Tooze, J.A., Dubey, P., In situ vaccination combined with androgen ablation and regulatory T-cell depletion reduces castration-resistant tumor burden in prostate-specific pten knockout mice. Cancer Research 70 (2010), 3473–3482.
-
(2010)
Cancer Research
, vol.70
, pp. 3473-3482
-
-
Akins, E.J.1
Moore, M.L.2
Tang, S.3
Willingham, M.C.4
Tooze, J.A.5
Dubey, P.6
-
4
-
-
42649099632
-
Antigen presentation: Prime time: Insights into cross-presentation
-
Allan, S., Antigen presentation: Prime time: Insights into cross-presentation. Nature Reviews. Immunology 8 (2008), 322–323.
-
(2008)
Nature Reviews. Immunology
, vol.8
, pp. 322-323
-
-
Allan, S.1
-
5
-
-
4444325043
-
TLR9 −/− and TLR9 +/+ mice display similar immune responses to a DNA vaccine
-
Babiuk, S., Mookherjee, N., Pontarollo, R., Griebel, P., Van Drunen Littel-Van Den Hurk, S., Hecker, R., Babiuk, L., TLR9 −/− and TLR9 +/+ mice display similar immune responses to a DNA vaccine. Immunology 113 (2004), 114–120.
-
(2004)
Immunology
, vol.113
, pp. 114-120
-
-
Babiuk, S.1
Mookherjee, N.2
Pontarollo, R.3
Griebel, P.4
Van Drunen Littel-Van Den Hurk, S.5
Hecker, R.6
Babiuk, L.7
-
6
-
-
84969919923
-
Myeloid-derived suppressor cells as intruders and targets: Clinical implications in cancer therapy
-
Baniyash, M., Myeloid-derived suppressor cells as intruders and targets: Clinical implications in cancer therapy. Cancer Immunology, Immunotherapy 65 (2016), 857–867.
-
(2016)
Cancer Immunology, Immunotherapy
, vol.65
, pp. 857-867
-
-
Baniyash, M.1
-
7
-
-
79951679142
-
Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses
-
Barber, G.N., Innate immune DNA sensing pathways: STING, AIMII and the regulation of interferon production and inflammatory responses. Current Opinion in Immunology 23 (2011), 10–20.
-
(2011)
Current Opinion in Immunology
, vol.23
, pp. 10-20
-
-
Barber, G.N.1
-
8
-
-
77954951895
-
DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer
-
Becker, J.T., Olson, B.M., Johnson, L.E., Davies, J.G., Dunphy, E.J., McNeel, D.G., DNA vaccine encoding prostatic acid phosphatase (PAP) elicits long-term T-cell responses in patients with recurrent prostate cancer. Journal of Immunotherapy 33 (2010), 639–647.
-
(2010)
Journal of Immunotherapy
, vol.33
, pp. 639-647
-
-
Becker, J.T.1
Olson, B.M.2
Johnson, L.E.3
Davies, J.G.4
Dunphy, E.J.5
McNeel, D.G.6
-
9
-
-
84875510924
-
Pathways of antigen processing
-
Blum, J.S., Wearsch, P.A., Cresswell, P., Pathways of antigen processing. Annual Review of Immunology 31 (2013), 443–473.
-
(2013)
Annual Review of Immunology
, vol.31
, pp. 443-473
-
-
Blum, J.S.1
Wearsch, P.A.2
Cresswell, P.3
-
10
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei, H., Paz-Ares, L., Horn, L., Spigel, D.R., Steins, M., Ready, N.E., Chow, L.Q., Vokes, E.E., Felip, E., Holgado, E., et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. The New England Journal of Medicine 373 (2015), 1627–1639.
-
(2015)
The New England Journal of Medicine
, vol.373
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
Spigel, D.R.4
Steins, M.5
Ready, N.E.6
Chow, L.Q.7
Vokes, E.E.8
Felip, E.9
Holgado, E.10
-
11
-
-
0034123851
-
Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer
-
Bot, A., Stan, A.C., Inaba, K., Steinman, R., Bona, C., Dendritic cells at a DNA vaccination site express the encoded influenza nucleoprotein and prime MHC class I-restricted cytolytic lymphocytes upon adoptive transfer. International Immunology 12 (2000), 825–832.
-
(2000)
International Immunology
, vol.12
, pp. 825-832
-
-
Bot, A.1
Stan, A.C.2
Inaba, K.3
Steinman, R.4
Bona, C.5
-
12
-
-
0032990254
-
Immunization through dermal delivery of protein-encoding DNA: A role for migratory dendritic cells
-
Bouloc, A., Walker, P., Grivel, J.-C., Vogel, J.C., Katz, S.I., Immunization through dermal delivery of protein-encoding DNA: A role for migratory dendritic cells. European Journal of Immunology 29 (1999), 446–454.
-
(1999)
European Journal of Immunology
, vol.29
, pp. 446-454
-
-
Bouloc, A.1
Walker, P.2
Grivel, J.-C.3
Vogel, J.C.4
Katz, S.I.5
-
13
-
-
0033432773
-
Coupling and uncoupling of tumor immunity and autoimmunity
-
Bowne, W.B., Srinivasan, R., Wolchok, J.D., Hawkins, W.G., Blachere, N.E., Dyall, R.,.. Houghton, A.N., Coupling and uncoupling of tumor immunity and autoimmunity. The Journal of Experimental Medicine 190 (1999), 1717–1722.
-
(1999)
The Journal of Experimental Medicine
, vol.190
, pp. 1717-1722
-
-
Bowne, W.B.1
Srinivasan, R.2
Wolchok, J.D.3
Hawkins, W.G.4
Blachere, N.E.5
Dyall, R.6
Houghton, A.N.7
-
14
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer, J.R., Drake, C.G., Wollner, I., Powderly, J.D., Picus, J., Sharfman, W.H., Stankevich, E., Pons, A., Salay, T.M., McMiller, T.L., et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates. Journal of Clinical Oncology 28 (2010), 3167–3175.
-
(2010)
Journal of Clinical Oncology
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
Stankevich, E.7
Pons, A.8
Salay, T.M.9
McMiller, T.L.10
-
15
-
-
0037471386
-
Super-activated interferon-regulatory factors can enhance plasmid immunization
-
Bramson, J.L., Dayball, K., Hall, J.R., Millar, J.B., Miller, M., Wan, Y.H.,.. Hiscott, J., Super-activated interferon-regulatory factors can enhance plasmid immunization. Vaccine 21 (2003), 1363–1370.
-
(2003)
Vaccine
, vol.21
, pp. 1363-1370
-
-
Bramson, J.L.1
Dayball, K.2
Hall, J.R.3
Millar, J.B.4
Miller, M.5
Wan, Y.H.6
Hiscott, J.7
-
16
-
-
79953221190
-
Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model
-
Cao, M., Xu, Y., Youn, J., Cabrera, R., Zhang, X., Gabrilovich, D.,.. Liu, C., Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model. Laboratory Investigation 91 (2011), 598–608.
-
(2011)
Laboratory Investigation
, vol.91
, pp. 598-608
-
-
Cao, M.1
Xu, Y.2
Youn, J.3
Cabrera, R.4
Zhang, X.5
Gabrilovich, D.6
Liu, C.7
-
17
-
-
0030698310
-
Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II–restricted viral epitope
-
Casares, S., Inaba, K., Brumeanu, T.-D., Steinman, R.M., Bona, C.A., Antigen presentation by dendritic cells after immunization with DNA encoding a major histocompatibility complex class II–restricted viral epitope. The Journal of Experimental Medicine 186 (1997), 1481–1486.
-
(1997)
The Journal of Experimental Medicine
, vol.186
, pp. 1481-1486
-
-
Casares, S.1
Inaba, K.2
Brumeanu, T.-D.3
Steinman, R.M.4
Bona, C.A.5
-
18
-
-
0041315884
-
Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo
-
Chen, Z.-Y., He, C.-Y., Ehrhardt, A., Kay, M.A., Minicircle DNA vectors devoid of bacterial DNA result in persistent and high-level transgene expression in vivo. Molecular Therapy: The Journal of the American Society of Gene Therapy 8 (2003), 495–500.
-
(2003)
Molecular Therapy: The Journal of the American Society of Gene Therapy
, vol.8
, pp. 495-500
-
-
Chen, Z.-Y.1
He, C.-Y.2
Ehrhardt, A.3
Kay, M.A.4
-
19
-
-
84934946628
-
Modulatory effect of CpG oligodeoxynucleotide on a DNA vaccine against nervous necrosis virus in orange-spotted grouper (Epinephelus coioides)
-
Chen, S.-P., Peng, R.-H., Chiou, P.P., Modulatory effect of CpG oligodeoxynucleotide on a DNA vaccine against nervous necrosis virus in orange-spotted grouper (Epinephelus coioides). Fish & Shellfish Immunology 45 (2015), 919–926.
-
(2015)
Fish & Shellfish Immunology
, vol.45
, pp. 919-926
-
-
Chen, S.-P.1
Peng, R.-H.2
Chiou, P.P.3
-
20
-
-
0035889924
-
Cross-priming as a predominant mechanism for inducing CD8(+) T cell responses in gene gun DNA immunization
-
Cho, J.H., Youn, J.W., Sung, Y.C., Cross-priming as a predominant mechanism for inducing CD8(+) T cell responses in gene gun DNA immunization. Journal of Immunology 167 (2001), 5549–5557.
-
(2001)
Journal of Immunology
, vol.167
, pp. 5549-5557
-
-
Cho, J.H.1
Youn, J.W.2
Sung, Y.C.3
-
21
-
-
0025906388
-
A generic intron increases gene expression in transgenic mice
-
Choi, T., Huang, M., Gorman, C., Jaenisch, R., A generic intron increases gene expression in transgenic mice. Molecular and Cellular Biology 11 (1991), 3070–3074.
-
(1991)
Molecular and Cellular Biology
, vol.11
, pp. 3070-3074
-
-
Choi, T.1
Huang, M.2
Gorman, C.3
Jaenisch, R.4
-
22
-
-
84874015160
-
DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity
-
Chuang, I., Sedegah, M., Cicatelli, S., Spring, M., Polhemus, M., Tamminga, C., Patterson, N., Guerrero, M., Bennett, J.W., McGrath, S., et al. DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity. PloS One, 8, 2013, e55571.
-
(2013)
PloS One
, vol.8
-
-
Chuang, I.1
Sedegah, M.2
Cicatelli, S.3
Spring, M.4
Polhemus, M.5
Tamminga, C.6
Patterson, N.7
Guerrero, M.8
Bennett, J.W.9
McGrath, S.10
-
23
-
-
84871011037
-
DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time
-
Chudley, L., McCann, K., Mander, A., Tjelle, T., Campos-Perez, J., Godeseth, R., Creak, A., Dobbyn, J., Johnson, B., Bass, P., et al. DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time. Cancer Immunology, Immunotherapy 61 (2012), 2161–2170.
-
(2012)
Cancer Immunology, Immunotherapy
, vol.61
, pp. 2161-2170
-
-
Chudley, L.1
McCann, K.2
Mander, A.3
Tjelle, T.4
Campos-Perez, J.5
Godeseth, R.6
Creak, A.7
Dobbyn, J.8
Johnson, B.9
Bass, P.10
-
24
-
-
79961048088
-
A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204)
-
Churchyard, G.J., Morgan, C., Adams, E., Hural, J., Graham, B.S., Moodie, Z., Grove, D., Gray, G., Bekker, L.-G., McElrath, M.J., et al. A phase IIA randomized clinical trial of a multiclade HIV-1 DNA prime followed by a multiclade rAd5 HIV-1 vaccine boost in healthy adults (HVTN204). PloS One, 6, 2011, e21225.
-
(2011)
PloS One
, vol.6
-
-
Churchyard, G.J.1
Morgan, C.2
Adams, E.3
Hural, J.4
Graham, B.S.5
Moodie, Z.6
Grove, D.7
Gray, G.8
Bekker, L.-G.9
McElrath, M.J.10
-
25
-
-
82055176771
-
Novel strategies to improve DNA vaccine immunogenicity
-
Coban, C., Kobiyama, K., Aoshi, T., Takeshita, F., Horii, T., Akira, S., Ishii, K.J., Novel strategies to improve DNA vaccine immunogenicity. Current Gene Therapy 11 (2011), 479–484.
-
(2011)
Current Gene Therapy
, vol.11
, pp. 479-484
-
-
Coban, C.1
Kobiyama, K.2
Aoshi, T.3
Takeshita, F.4
Horii, T.5
Akira, S.6
Ishii, K.J.7
-
26
-
-
0042884206
-
B-lymphocytes in bone marrow or lymph nodes can take up plasmid DNA after intramuscular delivery
-
Coelho-Castelo, A.A.M., Santos, R.R., Bonato, V.L.D., Jamur, M.C., Oliver, C., Silva, C.L., B-lymphocytes in bone marrow or lymph nodes can take up plasmid DNA after intramuscular delivery. Human Gene Therapy 14 (2003), 1279–1285.
-
(2003)
Human Gene Therapy
, vol.14
, pp. 1279-1285
-
-
Coelho-Castelo, A.A.M.1
Santos, R.R.2
Bonato, V.L.D.3
Jamur, M.C.4
Oliver, C.5
Silva, C.L.6
-
27
-
-
84961202366
-
Preclinical and clinical development of DNA vaccines for prostate cancer
-
Colluru, V.T., Johnson, L.E., Olson, B.M., McNeel, D.G., Preclinical and clinical development of DNA vaccines for prostate cancer. Urologic Oncology 34 (2013), 193–204.
-
(2013)
Urologic Oncology
, vol.34
, pp. 193-204
-
-
Colluru, V.T.1
Johnson, L.E.2
Olson, B.M.3
McNeel, D.G.4
-
28
-
-
85016377760
-
B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines
-
Colluru, V.T., McNeel, D.G., B lymphocytes as direct antigen-presenting cells for anti-tumor DNA vaccines. Oncotarget, 5, 2016.
-
(2016)
Oncotarget
, vol.5
-
-
Colluru, V.T.1
McNeel, D.G.2
-
29
-
-
84988723111
-
Mini-intronic plasmid vaccination elicits tolerant LAG3 + CD8 T cells and inferior anti-tumor responses
-
Colluru, V.T., Zahm, C.D., McNeel, D.G., Mini-intronic plasmid vaccination elicits tolerant LAG3 + CD8 T cells and inferior anti-tumor responses. Oncoimmunology, 5(10), 2016, e1223002.
-
(2016)
Oncoimmunology
, vol.5
, Issue.10
-
-
Colluru, V.T.1
Zahm, C.D.2
McNeel, D.G.3
-
30
-
-
0032711215
-
In vivo priming by DNA injection occurs predominantly by antigen transfer
-
Corr, M., von Damm, A., Lee, D.J., Tighe, H., In vivo priming by DNA injection occurs predominantly by antigen transfer. Journal of Immunology 163 (1999), 4721–4727.
-
(1999)
Journal of Immunology
, vol.163
, pp. 4721-4727
-
-
Corr, M.1
von Damm, A.2
Lee, D.J.3
Tighe, H.4
-
31
-
-
77955375356
-
Attenuated T cell responses to a high-potency ligand in vivo
-
Corse, E., Gottschalk, R.A., Krogsgaard, M., Allison, J.P., Attenuated T cell responses to a high-potency ligand in vivo. PLoS Biology, 8, 2010, e1000481.
-
(2010)
PLoS Biology
, vol.8
-
-
Corse, E.1
Gottschalk, R.A.2
Krogsgaard, M.3
Allison, J.P.4
-
32
-
-
70350234739
-
Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors
-
Curran, M.A., Allison, J.P., Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors. Cancer Research 69 (2009), 7747–7755.
-
(2009)
Cancer Research
, vol.69
, pp. 7747-7755
-
-
Curran, M.A.1
Allison, J.P.2
-
33
-
-
34248192988
-
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
-
Dalrymple, S.L., Becker, R.E., Isaacs, J.T., The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts. Prostate 67 (2007), 790–797.
-
(2007)
Prostate
, vol.67
, pp. 790-797
-
-
Dalrymple, S.L.1
Becker, R.E.2
Isaacs, J.T.3
-
34
-
-
77957682309
-
Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial
-
de Bono, J.S., Oudard, S., Ozguroglu, M., Hansen, S., Machiels, J.-P., Kocak, I., Gravis, G., Bodrogi, I., Mackenzie, M.J., Shen, L., et al. Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: A randomised open-label trial. Lancet 376 (2010), 1147–1154.
-
(2010)
Lancet
, vol.376
, pp. 1147-1154
-
-
de Bono, J.S.1
Oudard, S.2
Ozguroglu, M.3
Hansen, S.4
Machiels, J.-P.5
Kocak, I.6
Gravis, G.7
Bodrogi, I.8
Mackenzie, M.J.9
Shen, L.10
-
35
-
-
79957443342
-
Abiraterone and increased survival in metastatic prostate cancer
-
de Bono, J.S., Logothetis, C.J., Molina, A., Fizazi, K., North, S., Chu, L., Chi, K.N., Jones, R.J., Goodman, O.B., Saad, F., et al. Abiraterone and increased survival in metastatic prostate cancer. The New England Journal of Medicine 364 (2011), 1995–2005.
-
(2011)
The New England Journal of Medicine
, vol.364
, pp. 1995-2005
-
-
de Bono, J.S.1
Logothetis, C.J.2
Molina, A.3
Fizazi, K.4
North, S.5
Chu, L.6
Chi, K.N.7
Jones, R.J.8
Goodman, O.B.9
Saad, F.10
-
36
-
-
84883198880
-
Small molecule inhibitors of CXCR4
-
Debnath, B., Xu, S., Grande, F., Garofalo, A., Neamati, N., Small molecule inhibitors of CXCR4. Theranostics 3 (2013), 47–75.
-
(2013)
Theranostics
, vol.3
, pp. 47-75
-
-
Debnath, B.1
Xu, S.2
Grande, F.3
Garofalo, A.4
Neamati, N.5
-
37
-
-
84862855875
-
Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination
-
Desmet, C.J., Ishii, K.J., Nucleic acid sensing at the interface between innate and adaptive immunity in vaccination. Nature Reviews. Immunology 12 (2012), 479–491.
-
(2012)
Nature Reviews. Immunology
, vol.12
, pp. 479-491
-
-
Desmet, C.J.1
Ishii, K.J.2
-
38
-
-
84874978904
-
Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors
-
Diaz, C.M., Chiappori, A., Aurisicchio, L., Bagchi, A., Clark, J., Dubey, S., Fridman, A., Fabregas, J.C., Marshall, J., Scarselli, E., et al. Phase 1 studies of the safety and immunogenicity of electroporated HER2/CEA DNA vaccine followed by adenoviral boost immunization in patients with solid tumors. Journal of Translational Medicine, 11, 2013, 62.
-
(2013)
Journal of Translational Medicine
, vol.11
, pp. 62
-
-
Diaz, C.M.1
Chiappori, A.2
Aurisicchio, L.3
Bagchi, A.4
Clark, J.5
Dubey, S.6
Fridman, A.7
Fabregas, J.C.8
Marshall, J.9
Scarselli, E.10
-
39
-
-
84881317423
-
Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8 + T-cell responses
-
Dietz, W.M., Skinner, N.E.B., Hamilton, S.E., Jund, M.D., Heitfeld, S.M., Litterman, A.J., Hwu, P., Chen, Z.-Y., Salazar, A.M., Ohlfest, J.R., et al. Minicircle DNA is superior to plasmid DNA in eliciting antigen-specific CD8 + T-cell responses. Molecular Therapy 21 (2013), 1526–1535.
-
(2013)
Molecular Therapy
, vol.21
, pp. 1526-1535
-
-
Dietz, W.M.1
Skinner, N.E.B.2
Hamilton, S.E.3
Jund, M.D.4
Heitfeld, S.M.5
Litterman, A.J.6
Hwu, P.7
Chen, Z.-Y.8
Salazar, A.M.9
Ohlfest, J.R.10
-
40
-
-
84986287970
-
Protection against HPV-16-associated tumors requires the activation of CD8 + effector memory T cells and the control of myeloid-derived suppressor cells
-
Diniz, M.O., Sales, N.S., Silva, J.R., Ferreira, L.C.S., Protection against HPV-16-associated tumors requires the activation of CD8 + effector memory T cells and the control of myeloid-derived suppressor cells. Molecular Cancer Therapeutics 15 (2016), 1920–1930.
-
(2016)
Molecular Cancer Therapeutics
, vol.15
, pp. 1920-1930
-
-
Diniz, M.O.1
Sales, N.S.2
Silva, J.R.3
Ferreira, L.C.S.4
-
41
-
-
0038528567
-
Soluble cytokines can act as effective adjuvants in plasmid DNA vaccines targeting self tumor antigens
-
Disis, M.L., Shiota, F.M., McNeel, D.G., Knutson, K.L., Soluble cytokines can act as effective adjuvants in plasmid DNA vaccines targeting self tumor antigens. Immunobiology 207 (2003), 179–186.
-
(2003)
Immunobiology
, vol.207
, pp. 179-186
-
-
Disis, M.L.1
Shiota, F.M.2
McNeel, D.G.3
Knutson, K.L.4
-
42
-
-
84960423145
-
Nano-delivery vehicles/adjuvants for DNA vaccination against HIV
-
Dong, Y., Yang, J., Zhang, J., Zhang, X., Nano-delivery vehicles/adjuvants for DNA vaccination against HIV. Journal of Nanoscience and Nanotechnology 16 (2016), 2126–2133.
-
(2016)
Journal of Nanoscience and Nanotechnology
, vol.16
, pp. 2126-2133
-
-
Dong, Y.1
Yang, J.2
Zhang, J.3
Zhang, X.4
-
43
-
-
0029051152
-
Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus
-
Donnelly, J.J., Friedman, A., Martinez, D., Montgomery, D.L., Shiver, J.W., Motzel, S.L.,.. Liu, M.A., Preclinical efficacy of a prototype DNA vaccine: Enhanced protection against antigenic drift in influenza virus. Nature Medicine 1 (1995), 583–587.
-
(1995)
Nature Medicine
, vol.1
, pp. 583-587
-
-
Donnelly, J.J.1
Friedman, A.2
Martinez, D.3
Montgomery, D.L.4
Shiver, J.W.5
Motzel, S.L.6
Liu, M.A.7
-
44
-
-
85065699055
-
Toll-like receptors: The swiss army knife of immunity and vaccine development
-
Dowling, J.K., Mansell, A., Toll-like receptors: The swiss army knife of immunity and vaccine development. Clinical and Translational Immunology, 5, 2016, e85.
-
(2016)
Clinical and Translational Immunology
, vol.5
-
-
Dowling, J.K.1
Mansell, A.2
-
45
-
-
0033219613
-
Antibody-mediated endocytosis of G250 tumor-associated antigen allows targeted gene transfer to human renal cell carcinoma in vitro
-
Dürrbach, A., Angevin, E., Poncet, P., Rouleau, M., Chavanel, G., Chapel, A., Thierry, D., Gorter, A., Hirsch, R., Charpentier, B., et al. Antibody-mediated endocytosis of G250 tumor-associated antigen allows targeted gene transfer to human renal cell carcinoma in vitro. Cancer Gene Therapy 6 (1999), 564–571.
-
(1999)
Cancer Gene Therapy
, vol.6
, pp. 564-571
-
-
Dürrbach, A.1
Angevin, E.2
Poncet, P.3
Rouleau, M.4
Chavanel, G.5
Chapel, A.6
Thierry, D.7
Gorter, A.8
Hirsch, R.9
Charpentier, B.10
-
46
-
-
84881555063
-
DNA vaccine coding for the rhesus prostate specific antigen delivered by intradermal electroporation in patients with relapsed prostate cancer
-
Eriksson, F., Tötterman, T., Maltais, A.-K., Pisa, P., Yachnin, J., DNA vaccine coding for the rhesus prostate specific antigen delivered by intradermal electroporation in patients with relapsed prostate cancer. Vaccine 31 (2013), 3843–3848.
-
(2013)
Vaccine
, vol.31
, pp. 3843-3848
-
-
Eriksson, F.1
Tötterman, T.2
Maltais, A.-K.3
Pisa, P.4
Yachnin, J.5
-
47
-
-
84901345704
-
Mechanisms of microbubble-facilitated sonoporation for drug and gene delivery
-
Fan, Z., Kumon, R.E., Deng, C.X., Mechanisms of microbubble-facilitated sonoporation for drug and gene delivery. Therapeutic Delivery 5 (2014), 467–486.
-
(2014)
Therapeutic Delivery
, vol.5
, pp. 467-486
-
-
Fan, Z.1
Kumon, R.E.2
Deng, C.X.3
-
48
-
-
84971612325
-
Micro- and nanoparticulates for DNA vaccine delivery
-
Farris, E., Brown, D.M., Ramer-Tait, A.E., Pannier, A.K., Micro- and nanoparticulates for DNA vaccine delivery. Experimental Biology and Medicine 241 (2016), 919–929.
-
(2016)
Experimental Biology and Medicine
, vol.241
, pp. 919-929
-
-
Farris, E.1
Brown, D.M.2
Ramer-Tait, A.E.3
Pannier, A.K.4
-
49
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri, T., Yu, J.-W., Datta, P., Wu, J., Alnemri, E.S., AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature 458 (2009), 509–513.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.-W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
50
-
-
1642327429
-
Spontaneous transgenesis of human B lymphocytes
-
Filaci, G., Gerloni, M., Rizzi, M., Castiglioni, P., Chang, H.-D., Wheeler, M.C.,.. Zanetti, M., Spontaneous transgenesis of human B lymphocytes. Gene Therapy 11 (2004), 42–51.
-
(2004)
Gene Therapy
, vol.11
, pp. 42-51
-
-
Filaci, G.1
Gerloni, M.2
Rizzi, M.3
Castiglioni, P.4
Chang, H.-D.5
Wheeler, M.C.6
Zanetti, M.7
-
51
-
-
84890346971
-
Synthetic DNA vaccines: Improved vaccine potency by electroporation and co-delivered genetic adjuvants
-
Flingai, S., Czerwonko, M., Goodman, J., Kudchodkar, S.B., Muthumani, K., Weiner, D.B., Synthetic DNA vaccines: Improved vaccine potency by electroporation and co-delivered genetic adjuvants. Immunotherapy and Vaccines, 4, 2013, 354.
-
(2013)
Immunotherapy and Vaccines
, vol.4
, pp. 354
-
-
Flingai, S.1
Czerwonko, M.2
Goodman, J.3
Kudchodkar, S.B.4
Muthumani, K.5
Weiner, D.B.6
-
52
-
-
84874872137
-
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
-
Frederick, D.T., Piris, A., Cogdill, A.P., Cooper, Z.A., Lezcano, C., Ferrone, C.R., Mitra, D., Boni, A., Newton, L.P., Liu, C., et al. BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma. Clinical Cancer Research 19 (2013), 1225–1231.
-
(2013)
Clinical Cancer Research
, vol.19
, pp. 1225-1231
-
-
Frederick, D.T.1
Piris, A.2
Cogdill, A.P.3
Cooper, Z.A.4
Lezcano, C.5
Ferrone, C.R.6
Mitra, D.7
Boni, A.8
Newton, L.P.9
Liu, C.10
-
53
-
-
1842581995
-
Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene
-
Frelin, L., Ahlén, G., Alheim, M., Weiland, O., Barnfield, C., Liljeström, P., Sällberg, M., Codon optimization and mRNA amplification effectively enhances the immunogenicity of the hepatitis C virus nonstructural 3/4A gene. Gene Therapy 11 (2004), 522–533.
-
(2004)
Gene Therapy
, vol.11
, pp. 522-533
-
-
Frelin, L.1
Ahlén, G.2
Alheim, M.3
Weiland, O.4
Barnfield, C.5
Liljeström, P.6
Sällberg, M.7
-
54
-
-
0030999062
-
Protective cellular immunity: Cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization
-
Fu, T.M., Friedman, A., Ulmer, J.B., Liu, M.A., Donnelly, J.J., Protective cellular immunity: Cytotoxic T-lymphocyte responses against dominant and recessive epitopes of influenza virus nucleoprotein induced by DNA immunization. Journal of Virology 71 (1997), 2715–2721.
-
(1997)
Journal of Virology
, vol.71
, pp. 2715-2721
-
-
Fu, T.M.1
Friedman, A.2
Ulmer, J.B.3
Liu, M.A.4
Donnelly, J.J.5
-
55
-
-
0030820743
-
Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes
-
Fu, T.M., Ulmer, J.B., Caulfield, M.J., Deck, R.R., Friedman, A., Wang, S.,.. Liu, M.A., Priming of cytotoxic T lymphocytes by DNA vaccines: Requirement for professional antigen presenting cells and evidence for antigen transfer from myocytes. Molecular Medicine 3 (1997), 362–371.
-
(1997)
Molecular Medicine
, vol.3
, pp. 362-371
-
-
Fu, T.M.1
Ulmer, J.B.2
Caulfield, M.J.3
Deck, R.R.4
Friedman, A.5
Wang, S.6
Liu, M.A.7
-
56
-
-
84928199174
-
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
-
Fu, J., Kanne, D.B., Leong, M., Glickman, L.H., McWhirter, S.M., Lemmens, E., Mechette, K., Leong, J.J., Lauer, P., Liu, W., et al. STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade. Science Translational Medicine, 7, 2015, 283ra52.
-
(2015)
Science Translational Medicine
, vol.7
-
-
Fu, J.1
Kanne, D.B.2
Leong, M.3
Glickman, L.H.4
McWhirter, S.M.5
Lemmens, E.6
Mechette, K.7
Leong, J.J.8
Lauer, P.9
Liu, W.10
-
57
-
-
84955261926
-
Combination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine
-
Gableh, F., Saeidi, M., Hemati, S., Hamdi, K., Soleimanjahi, H., Gorji, A., Ghaemi, A., Combination of the toll like receptor agonist and α-Galactosylceramide as an efficient adjuvant for cancer vaccine. Journal of Biomedical Science, 23, 2016, 16.
-
(2016)
Journal of Biomedical Science
, vol.23
, pp. 16
-
-
Gableh, F.1
Saeidi, M.2
Hemati, S.3
Hamdi, K.4
Soleimanjahi, H.5
Gorji, A.6
Ghaemi, A.7
-
58
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
Gabrilovich, D.I., Ostrand-Rosenberg, S., Bronte, V., Coordinated regulation of myeloid cells by tumours. Nature Reviews. Immunology 12 (2012), 253–268.
-
(2012)
Nature Reviews. Immunology
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
59
-
-
38849142632
-
Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity
-
Garcia-Hernandez, M.d.l.L., Gray, A., Hubby, B., Klinger, O.J., Kast, W.M., Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity. Cancer Research 68 (2008), 861–869.
-
(2008)
Cancer Research
, vol.68
, pp. 861-869
-
-
Garcia-Hernandez, M.D.L.L.1
Gray, A.2
Hubby, B.3
Klinger, O.J.4
Kast, W.M.5
-
60
-
-
0842282177
-
DNA vaccines: Improving expression of antigens
-
Garmory, H.S., Brown, K.A., Titball, R.W., DNA vaccines: Improving expression of antigens. Genetic Vaccines and Therapy, 1, 2003, 2.
-
(2003)
Genetic Vaccines and Therapy
, vol.1
, pp. 2
-
-
Garmory, H.S.1
Brown, K.A.2
Titball, R.W.3
-
61
-
-
84929481480
-
Pembrolizumab for the treatment of non-small-cell lung cancer
-
Garon, E.B., Rizvi, N.A., Hui, R., Leighl, N., Balmanoukian, A.S., Eder, J.P., Patnaik, A., Aggarwal, C., Gubens, M., Horn, L., et al. Pembrolizumab for the treatment of non-small-cell lung cancer. The New England Journal of Medicine 372 (2015), 2018–2028.
-
(2015)
The New England Journal of Medicine
, vol.372
, pp. 2018-2028
-
-
Garon, E.B.1
Rizvi, N.A.2
Hui, R.3
Leighl, N.4
Balmanoukian, A.S.5
Eder, J.P.6
Patnaik, A.7
Aggarwal, C.8
Gubens, M.9
Horn, L.10
-
62
-
-
84959462314
-
Genetic immunization with in vivo dendritic cell targeting liposomal DNA vaccine carrier induces long-lasting anti-tumor immune response
-
Garu, A., Moku, G., Gulla, S.K., Chaudhuri, A., Genetic immunization with in vivo dendritic cell targeting liposomal DNA vaccine carrier induces long-lasting anti-tumor immune response. Molecular Therapy 24 (2016), 385–397.
-
(2016)
Molecular Therapy
, vol.24
, pp. 385-397
-
-
Garu, A.1
Moku, G.2
Gulla, S.K.3
Chaudhuri, A.4
-
63
-
-
1642417348
-
T cell immunity using transgenic B lymphocytes
-
Gerloni, M., Rizzi, M., Castiglioni, P., Zanetti, M., T cell immunity using transgenic B lymphocytes. Proceedings of the National Academy of Sciences of the United States of America 101 (2004), 3892–3897.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 3892-3897
-
-
Gerloni, M.1
Rizzi, M.2
Castiglioni, P.3
Zanetti, M.4
-
64
-
-
62449213245
-
NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells
-
Gnjatic, S., Altorki, N.K., Tang, D.N., Tu, S.-M., Kundra, V., Ritter, G.,.. Sharma, P., NY-ESO-1 DNA vaccine induces T-cell responses that are suppressed by regulatory T cells. Clinical Cancer Research 15 (2009), 2130–2139.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 2130-2139
-
-
Gnjatic, S.1
Altorki, N.K.2
Tang, D.N.3
Tu, S.-M.4
Kundra, V.5
Ritter, G.6
Sharma, P.7
-
65
-
-
11144353596
-
CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems
-
Gregor, P.D., Wolchok, J.D., Ferrone, C.R., Buchinshky, H., Guevara-Patiño, J.A., Perales, M.-A., Mortazavi, F., Bacich, D., Heston, W., Latouche, J.-B., et al. CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems. Vaccine 22 (2004), 1700–1708.
-
(2004)
Vaccine
, vol.22
, pp. 1700-1708
-
-
Gregor, P.D.1
Wolchok, J.D.2
Ferrone, C.R.3
Buchinshky, H.4
Guevara-Patiño, J.A.5
Perales, M.-A.6
Mortazavi, F.7
Bacich, D.8
Heston, W.9
Latouche, J.-B.10
-
66
-
-
82755181916
-
Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor
-
Grosenbaugh, D.A., Leard, A.T., Bergman, P.J., Klein, M.K., Meleo, K., Susaneck, S., Hess, P.R., Jankowski, M.K., Jones, P.D., Leibman, N.F., et al. Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor. American Journal of Veterinary Research 72 (2011), 1631–1638.
-
(2011)
American Journal of Veterinary Research
, vol.72
, pp. 1631-1638
-
-
Grosenbaugh, D.A.1
Leard, A.T.2
Bergman, P.J.3
Klein, M.K.4
Meleo, K.5
Susaneck, S.6
Hess, P.R.7
Jankowski, M.K.8
Jones, P.D.9
Leibman, N.F.10
-
67
-
-
0033866842
-
Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity
-
Hawkins, W.G., Gold, J.S., Dyall, R., Wolchok, J.D., Hoos, A., Bowne, W.B.,.. Lewis, J.J., Immunization with DNA coding for gp100 results in CD4 T-cell independent antitumor immunity. Surgery 128 (2000), 273–280.
-
(2000)
Surgery
, vol.128
, pp. 273-280
-
-
Hawkins, W.G.1
Gold, J.S.2
Dyall, R.3
Wolchok, J.D.4
Hoos, A.5
Bowne, W.B.6
Lewis, J.J.7
-
68
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi, H., Takeuchi, O., Kawai, T., Kaisho, T., Sato, S., Sanjo, H., Matsumoto, M., Hoshino, K., Wagner, H., Takeda, K., et al. A Toll-like receptor recognizes bacterial DNA. Nature 408 (2000), 740–745.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
Kaisho, T.4
Sato, S.5
Sanjo, H.6
Matsumoto, M.7
Hoshino, K.8
Wagner, H.9
Takeda, K.10
-
69
-
-
84901334642
-
Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy
-
Highfill, S.L., Cui, Y., Giles, A.J., Smith, J.P., Zhang, H., Morse, E.,.. Mackall, C.L., Disruption of CXCR2-mediated MDSC tumor trafficking enhances anti-PD1 efficacy. Science Translational Medicine, 6, 2014, 237ra67.
-
(2014)
Science Translational Medicine
, vol.6
-
-
Highfill, S.L.1
Cui, Y.2
Giles, A.J.3
Smith, J.P.4
Zhang, H.5
Morse, E.6
Mackall, C.L.7
-
70
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F.S., O'Day, S.J., McDermott, D.F., Weber, R.W., Sosman, J.A., Haanen, J.B., Gonzalez, R., Robert, C., Schadendorf, D., Hassel, J.C., et al. Improved survival with ipilimumab in patients with metastatic melanoma. The New England Journal of Medicine 363 (2010), 711–723.
-
(2010)
The New England Journal of Medicine
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
-
71
-
-
17844363748
-
B lymphocytes participate in cross-presentation of antigen following gene gun vaccination
-
Hon, H., Oran, A., Brocker, T., Jacob, J., B lymphocytes participate in cross-presentation of antigen following gene gun vaccination. Journal of Immunology 174 (2005), 5233–5242.
-
(2005)
Journal of Immunology
, vol.174
, pp. 5233-5242
-
-
Hon, H.1
Oran, A.2
Brocker, T.3
Jacob, J.4
-
72
-
-
84910135021
-
Altered peptide ligands revisited: Vaccine design through chemically modified HLA-A2-restricted T cell epitopes
-
Hoppes, R., Oostvogels, R., Luimstra, J.J., Wals, K., Toebes, M., Bies, L., Ekkebus, R., Rijal, P., Celie, P.H.N., Huang, J.H., et al. Altered peptide ligands revisited: Vaccine design through chemically modified HLA-A2-restricted T cell epitopes. Journal of Immunology 193 (2014), 4803–4813.
-
(2014)
Journal of Immunology
, vol.193
, pp. 4803-4813
-
-
Hoppes, R.1
Oostvogels, R.2
Luimstra, J.J.3
Wals, K.4
Toebes, M.5
Bies, L.6
Ekkebus, R.7
Rijal, P.8
Celie, P.H.N.9
Huang, J.H.10
-
73
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung, V., Ablasser, A., Charrel-Dennis, M., Bauernfeind, F., Horvath, G., Caffrey, D.R.,.. Fitzgerald, K.A., AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature 458 (2009), 514–518.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
Fitzgerald, K.A.7
-
74
-
-
0034194329
-
Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade
-
Hurwitz, A.A., Foster, B.A., Kwon, E.D., Truong, T., Choi, E.M., Greenberg, N.M.,.. Allison, J.P., Combination immunotherapy of primary prostate cancer in a transgenic mouse model using CTLA-4 blockade. Cancer Research 60 (2000), 2444–2448.
-
(2000)
Cancer Research
, vol.60
, pp. 2444-2448
-
-
Hurwitz, A.A.1
Foster, B.A.2
Kwon, E.D.3
Truong, T.4
Choi, E.M.5
Greenberg, N.M.6
Allison, J.P.7
-
75
-
-
84883851607
-
Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine
-
Igoucheva, O., Grazzini, M., Pidich, A., Kemp, D.M., Larijani, M., Farber, M.,.. Alexeev, V., Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine. Gene Therapy 20 (2013), 939–948.
-
(2013)
Gene Therapy
, vol.20
, pp. 939-948
-
-
Igoucheva, O.1
Grazzini, M.2
Pidich, A.3
Kemp, D.M.4
Larijani, M.5
Farber, M.6
Alexeev, V.7
-
76
-
-
84874342427
-
Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment
-
Isaacs, J.T., Antony, L., Dalrymple, S.L., Brennen, W.N., Gerber, S., Hammers, H., Wissing, M., Kachhap, S., Luo, J., Xing, L., et al. Tasquinimod is an allosteric modulator of HDAC4 survival signaling within the compromised cancer microenvironment. Cancer Research 73 (2013), 1386–1399.
-
(2013)
Cancer Research
, vol.73
, pp. 1386-1399
-
-
Isaacs, J.T.1
Antony, L.2
Dalrymple, S.L.3
Brennen, W.N.4
Gerber, S.5
Hammers, H.6
Wissing, M.7
Kachhap, S.8
Luo, J.9
Xing, L.10
-
77
-
-
70349943834
-
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
-
Ishikawa, H., Ma, Z., Barber, G.N., STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity. Nature 461 (2009), 788–792.
-
(2009)
Nature
, vol.461
, pp. 788-792
-
-
Ishikawa, H.1
Ma, Z.2
Barber, G.N.3
-
78
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
(80-.)
-
Iwasaki, A., Medzhitov, R., Regulation of adaptive immunity by the innate immune system. Science 327 (2010), 291–295 (80-.).
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
79
-
-
66949176637
-
Tumor regression following DNA vaccination and regulatory T cell depletion in neu transgenic mice leads to an increased risk for autoimmunity
-
Jacob, J.B., Kong, Y.M., Nalbantoglu, I., Snower, D.P., Wei, W.-Z., Tumor regression following DNA vaccination and regulatory T cell depletion in neu transgenic mice leads to an increased risk for autoimmunity. Journal of Immunology 182 (2009), 5873–5881.
-
(2009)
Journal of Immunology
, vol.182
, pp. 5873-5881
-
-
Jacob, J.B.1
Kong, Y.M.2
Nalbantoglu, I.3
Snower, D.P.4
Wei, W.-Z.5
-
80
-
-
84864332935
-
Cross-presentation by dendritic cells
-
Joffre, O.P., Segura, E., Savina, A., Amigorena, S., Cross-presentation by dendritic cells. Nature Reviews. Immunology 12 (2012), 557–569.
-
(2012)
Nature Reviews. Immunology
, vol.12
, pp. 557-569
-
-
Joffre, O.P.1
Segura, E.2
Savina, A.3
Amigorena, S.4
-
81
-
-
84886944765
-
Immunization with a prostate cancer xenoantigen elicits a xenoantigen epitope-specific T-cell response
-
Johnson, L.E., Frye, T.P., McNeel, D.G., Immunization with a prostate cancer xenoantigen elicits a xenoantigen epitope-specific T-cell response. OncoImmunology 1 (2012), 1546–1556.
-
(2012)
OncoImmunology
, vol.1
, pp. 1546-1556
-
-
Johnson, L.E.1
Frye, T.P.2
McNeel, D.G.3
-
82
-
-
84878414390
-
TLR agonists: Our best frenemy in cancer immunotherapy
-
Kaczanowska, S., Joseph, A.M., Davila, E., TLR agonists: Our best frenemy in cancer immunotherapy. Journal of Leukocyte Biology 93 (2013), 847–863.
-
(2013)
Journal of Leukocyte Biology
, vol.93
, pp. 847-863
-
-
Kaczanowska, S.1
Joseph, A.M.2
Davila, E.3
-
83
-
-
78149477335
-
Sipuleucel-T immunotherapy for castration-resistant prostate cancer
-
Kantoff, P.W., Higano, C.S., Shore, N.D., Berger, E.R., Small, E.J., Penson, D.F., Redfern, C.H., Ferrari, A.C., Dreicer, R., Sims, R.B., et al. Sipuleucel-T immunotherapy for castration-resistant prostate cancer. The New England Journal of Medicine 363 (2010), 411–422.
-
(2010)
The New England Journal of Medicine
, vol.363
, pp. 411-422
-
-
Kantoff, P.W.1
Higano, C.S.2
Shore, N.D.3
Berger, E.R.4
Small, E.J.5
Penson, D.F.6
Redfern, C.H.7
Ferrari, A.C.8
Dreicer, R.9
Sims, R.B.10
-
84
-
-
79955777161
-
Interplay between CD8α + dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses
-
Kapadia, D., Sadikovic, A., Vanloubbeeck, Y., Brockstedt, D., Fong, L., Interplay between CD8α + dendritic cells and monocytes in response to Listeria monocytogenes infection attenuates T cell responses. PloS One, 6, 2011, e19376.
-
(2011)
PloS One
, vol.6
-
-
Kapadia, D.1
Sadikovic, A.2
Vanloubbeeck, Y.3
Brockstedt, D.4
Fong, L.5
-
85
-
-
84887512876
-
CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis
-
Katoh, H., Wang, D., Daikoku, T., Sun, H., Dey, S.K., Dubois, R.N., CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis. Cancer Cell 24 (2013), 631–644.
-
(2013)
Cancer Cell
, vol.24
, pp. 631-644
-
-
Katoh, H.1
Wang, D.2
Daikoku, T.3
Sun, H.4
Dey, S.K.5
Dubois, R.N.6
-
86
-
-
78650028269
-
A robust system for production of minicircle DNA vectors
-
Kay, M.A., He, C.-Y., Chen, Z.-Y., A robust system for production of minicircle DNA vectors. Nature Biotechnology 28 (2010), 1287–1289.
-
(2010)
Nature Biotechnology
, vol.28
, pp. 1287-1289
-
-
Kay, M.A.1
He, C.-Y.2
Chen, Z.-Y.3
-
87
-
-
84866918738
-
Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma
-
Khalili, J.S., Liu, S., Rodríguez-Cruz, T.G., Whittington, M., Wardell, S., Liu, C., Zhang, M., Cooper, Z.A., Frederick, D.T., Li, Y., et al. Oncogenic BRAF(V600E) promotes stromal cell-mediated immunosuppression via induction of interleukin-1 in melanoma. Clinical Cancer Research 18 (2012), 5329–5340.
-
(2012)
Clinical Cancer Research
, vol.18
, pp. 5329-5340
-
-
Khalili, J.S.1
Liu, S.2
Rodríguez-Cruz, T.G.3
Whittington, M.4
Wardell, S.5
Liu, C.6
Zhang, M.7
Cooper, Z.A.8
Frederick, D.T.9
Li, Y.10
-
88
-
-
37249067503
-
CD8 + Foxp3 + regulatory T cells mediate immunosuppression in prostate cancer
-
Kiniwa, Y., Miyahara, Y., Wang, H.Y., Peng, W., Peng, G., Wheeler, T.M.,.. Wang, R.-F., CD8 + Foxp3 + regulatory T cells mediate immunosuppression in prostate cancer. Clinical Cancer Research 13 (2007), 6947–6958.
-
(2007)
Clinical Cancer Research
, vol.13
, pp. 6947-6958
-
-
Kiniwa, Y.1
Miyahara, Y.2
Wang, H.Y.3
Peng, W.4
Peng, G.5
Wheeler, T.M.6
Wang, R.-F.7
-
89
-
-
84866060623
-
Immunotherapy of cancer in 2012
-
Kirkwood, J.M., Butterfield, L.H., Tarhini, A.A., Zarour, H., Kalinski, P., Ferrone, S., Immunotherapy of cancer in 2012. CA: a Cancer Journal for Clinicians 62 (2012), 309–335.
-
(2012)
CA: a Cancer Journal for Clinicians
, vol.62
, pp. 309-335
-
-
Kirkwood, J.M.1
Butterfield, L.H.2
Tarhini, A.A.3
Zarour, H.4
Kalinski, P.5
Ferrone, S.6
-
90
-
-
84906347236
-
Breaking immune tolerance by targeting CD25 + regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer
-
Klyushnenkova, E.N., Riabov, V.B., Kouiavskaia, D.V., Wietsma, A., Zhan, M., Alexander, R.B., Breaking immune tolerance by targeting CD25 + regulatory T cells is essential for the anti-tumor effect of the CTLA-4 blockade in an HLA-DR transgenic mouse model of prostate cancer. Prostate 74 (2014), 1423–1432.
-
(2014)
Prostate
, vol.74
, pp. 1423-1432
-
-
Klyushnenkova, E.N.1
Riabov, V.B.2
Kouiavskaia, D.V.3
Wietsma, A.4
Zhan, M.5
Alexander, R.B.6
-
91
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
Ko, J.S., Zea, A.H., Rini, B.I., Ireland, J.L., Elson, P., Cohen, P., Golshayan, A., Rayman, P.A., Wood, L., Garcia, J., et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clinical Cancer Research 15 (2009), 2148–2157.
-
(2009)
Clinical Cancer Research
, vol.15
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
Ireland, J.L.4
Elson, P.5
Cohen, P.6
Golshayan, A.7
Rayman, P.A.8
Wood, L.9
Garcia, J.10
-
92
-
-
84906899823
-
Innate immune signaling by, and genetic adjuvants for DNA vaccination
-
Kobiyama, K., Jounai, N., Aoshi, T., Tozuka, M., Takeshita, F., Coban, C., Ishii, K.J., Innate immune signaling by, and genetic adjuvants for DNA vaccination. Vaccine 1 (2013), 278–292.
-
(2013)
Vaccine
, vol.1
, pp. 278-292
-
-
Kobiyama, K.1
Jounai, N.2
Aoshi, T.3
Tozuka, M.4
Takeshita, F.5
Coban, C.6
Ishii, K.J.7
-
93
-
-
79151473356
-
Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression
-
Krupa, M., Canamero, M., Gomez, C.E., Najera, J.L., Gil, J., Esteban, M., Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression. Vaccine 29 (2011), 1504–1513.
-
(2011)
Vaccine
, vol.29
, pp. 1504-1513
-
-
Krupa, M.1
Canamero, M.2
Gomez, C.E.3
Najera, J.L.4
Gil, J.5
Esteban, M.6
-
94
-
-
0037121945
-
Regulatory CD4 + CD25 + T cells restrict memory CD8 + T cell responses
-
Kursar, M., Bonhagen, K., Fensterle, J., Köhler, A., Hurwitz, R., Kamradt, T.,.. Mittrücker, H.-W., Regulatory CD4 + CD25 + T cells restrict memory CD8 + T cell responses. The Journal of Experimental Medicine 196 (2002), 1585–1592.
-
(2002)
The Journal of Experimental Medicine
, vol.196
, pp. 1585-1592
-
-
Kursar, M.1
Bonhagen, K.2
Fensterle, J.3
Köhler, A.4
Hurwitz, R.5
Kamradt, T.6
Mittrücker, H.-W.7
-
95
-
-
84901641673
-
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): A multicentre, randomised, double-blind, phase 3 trial
-
Kwon, E.D., Drake, C.G., Scher, H.I., Fizazi, K., Bossi, A., van den Eertwegh, A.J.M., Krainer, M., Houede, N., Santos, R., Mahammedi, H., et al. Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): A multicentre, randomised, double-blind, phase 3 trial. The Lancet Oncology 15 (2014), 700–712.
-
(2014)
The Lancet Oncology
, vol.15
, pp. 700-712
-
-
Kwon, E.D.1
Drake, C.G.2
Scher, H.I.3
Fizazi, K.4
Bossi, A.5
van den Eertwegh, A.J.M.6
Krainer, M.7
Houede, N.8
Santos, R.9
Mahammedi, H.10
-
96
-
-
84871687263
-
A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease
-
Lambracht-Washington, D., Qu, B., Fu, M., Anderson, L.D., Eagar, T.N., Stüve, O., Rosenberg, R.N., A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease. Journal of Neuroimmunology 254 (2013), 63–68.
-
(2013)
Journal of Neuroimmunology
, vol.254
, pp. 63-68
-
-
Lambracht-Washington, D.1
Qu, B.2
Fu, M.3
Anderson, L.D.4
Eagar, T.N.5
Stüve, O.6
Rosenberg, R.N.7
-
97
-
-
84928530151
-
APC targeted micelle for enhanced intradermal delivery of hepatitis B DNA vaccine
-
Layek, B., Lipp, L., Singh, J., APC targeted micelle for enhanced intradermal delivery of hepatitis B DNA vaccine. Journal of Controlled Release 207 (2015), 143–153.
-
(2015)
Journal of Controlled Release
, vol.207
, pp. 143-153
-
-
Layek, B.1
Lipp, L.2
Singh, J.3
-
98
-
-
33750001550
-
Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide
-
Lazoura, E., Lodding, J., Farrugia, W., Ramsland, P.a., Stevens, J., Wilson, I.a.,.. Apostolopoulos, V., Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide. Immunology 119 (2006), 306–316.
-
(2006)
Immunology
, vol.119
, pp. 306-316
-
-
Lazoura, E.1
Lodding, J.2
Farrugia, W.3
Ramsland, P.A.4
Stevens, J.5
Wilson, I.A.6
Apostolopoulos, V.7
-
99
-
-
81855182191
-
DNA priming and influenza vaccine immunogenicity: Two phase 1 open label randomised clinical trials
-
Ledgerwood, J.E., Wei, C.-J., Hu, Z., Gordon, I.J., Enama, M.E., Hendel, C.S., McTamney, P.M., Pearce, M.B., Yassine, H.M., Boyington, J.C., et al. DNA priming and influenza vaccine immunogenicity: Two phase 1 open label randomised clinical trials. The Lancet Infectious Diseases 11 (2011), 916–924.
-
(2011)
The Lancet Infectious Diseases
, vol.11
, pp. 916-924
-
-
Ledgerwood, J.E.1
Wei, C.-J.2
Hu, Z.3
Gordon, I.J.4
Enama, M.E.5
Hendel, C.S.6
McTamney, P.M.7
Pearce, M.B.8
Yassine, H.M.9
Boyington, J.C.10
-
100
-
-
79956122546
-
Antitumor therapeutic and antimetastatic activity of electroporation-delivered human papillomavirus 16 E7 DNA vaccines: A possible mechanism for enhanced tumor control
-
Lee, I.H., Park, J.-B., Cheong, M., Choi, Y.S., Park, D., Sin, J.-I., Antitumor therapeutic and antimetastatic activity of electroporation-delivered human papillomavirus 16 E7 DNA vaccines: A possible mechanism for enhanced tumor control. DNA and Cell Biology 30 (2011), 975–985.
-
(2011)
DNA and Cell Biology
, vol.30
, pp. 975-985
-
-
Lee, I.H.1
Park, J.-B.2
Cheong, M.3
Choi, Y.S.4
Park, D.5
Sin, J.-I.6
-
101
-
-
84858008055
-
Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers
-
Lee, J., Li, L., Gretz, N., Gebert, J., Dihlmann, S., Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers. Oncogene 31 (2012), 1242–1253.
-
(2012)
Oncogene
, vol.31
, pp. 1242-1253
-
-
Lee, J.1
Li, L.2
Gretz, N.3
Gebert, J.4
Dihlmann, S.5
-
102
-
-
84930850526
-
Improvement of the immunogenicity of porcine circovirus type 2 DNA vaccine by recombinant ORF2 gene and CpG motifs
-
Li, J., Shi, J.-L., Wu, X.-Y., Fu, F., Yu, J., Yuan, X.-Y., Peng, Z., Cong, X.-Y., Xu, S.-J., Sun, W.-B., et al. Improvement of the immunogenicity of porcine circovirus type 2 DNA vaccine by recombinant ORF2 gene and CpG motifs. Viral Immunology 28 (2015), 290–296.
-
(2015)
Viral Immunology
, vol.28
, pp. 290-296
-
-
Li, J.1
Shi, J.-L.2
Wu, X.-Y.3
Fu, F.4
Yu, J.5
Yuan, X.-Y.6
Peng, Z.7
Cong, X.-Y.8
Xu, S.-J.9
Sun, W.-B.10
-
103
-
-
33745684793
-
A DNA vaccine encoding a codon-optimized human papillomavirus type 16 E6 gene enhances CTL response and anti-tumor activity
-
Lin, C.-T., Tsai, Y.-C., He, L., Calizo, R., Chou, H.-H., Chang, T.-C.,.. Lai, C.-H., A DNA vaccine encoding a codon-optimized human papillomavirus type 16 E6 gene enhances CTL response and anti-tumor activity. Journal of Biomedical Science 13 (2006), 481–488.
-
(2006)
Journal of Biomedical Science
, vol.13
, pp. 481-488
-
-
Lin, C.-T.1
Tsai, Y.-C.2
He, L.3
Calizo, R.4
Chou, H.-H.5
Chang, T.-C.6
Lai, C.-H.7
-
104
-
-
84905275330
-
Microbubble-mediated sonoporation for highly efficient transfection of recalcitrant human B- cell lines
-
Ling Yong, C.L., Siak-Wei Ow, D., Tandiono, T., Mei Heng, L.L., Kwok-Keung Chan, K., Ohl, C.-D.,.. Boon-Hwa Choo, A., Microbubble-mediated sonoporation for highly efficient transfection of recalcitrant human B- cell lines. Biotechnology Journal 9 (2014), 1081–1087.
-
(2014)
Biotechnology Journal
, vol.9
, pp. 1081-1087
-
-
Ling Yong, C.L.1
Siak-Wei Ow, D.2
Tandiono, T.3
Mei Heng, L.L.4
Kwok-Keung Chan, K.5
Ohl, C.-D.6
Boon-Hwa Choo, A.7
-
105
-
-
78650573649
-
DNA vaccines: An historical perspective and view to the future
-
Liu, M.A., DNA vaccines: An historical perspective and view to the future. Immunological Reviews 239 (2011), 62–84.
-
(2011)
Immunological Reviews
, vol.239
, pp. 62-84
-
-
Liu, M.A.1
-
106
-
-
84982834076
-
AIM2 inhibits autophagy and IFN-β production during M. bovis infection
-
Liu, C., Yue, R., Yang, Y., Cui, Y., Yang, L., Zhao, D., Zhou, X., AIM2 inhibits autophagy and IFN-β production during M. bovis infection. Oncotarget 7 (2016), 46972–46987.
-
(2016)
Oncotarget
, vol.7
, pp. 46972-46987
-
-
Liu, C.1
Yue, R.2
Yang, Y.3
Cui, Y.4
Yang, L.5
Zhao, D.6
Zhou, X.7
-
107
-
-
84925711178
-
Codon optimization of the human papillomavirus E7 oncogene induces a CD8 + T cell response to a cryptic epitope not harbored by wild-type E7
-
Lorenz, F.K.M., Wilde, S., Voigt, K., Kieback, E., Mosetter, B., Schendel, D.J., Uckert, W., Codon optimization of the human papillomavirus E7 oncogene induces a CD8 + T cell response to a cryptic epitope not harbored by wild-type E7. PloS One, 10, 2015, e0121633.
-
(2015)
PloS One
, vol.10
-
-
Lorenz, F.K.M.1
Wilde, S.2
Voigt, K.3
Kieback, E.4
Mosetter, B.5
Schendel, D.J.6
Uckert, W.7
-
108
-
-
70350128929
-
DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer
-
Low, L., Mander, A., McCann, K., Dearnaley, D., Tjelle, T., Mathiesen, I.,.. Ottensmeier, C.H., DNA vaccination with electroporation induces increased antibody responses in patients with prostate cancer. Human Gene Therapy 20 (2009), 1269–1278.
-
(2009)
Human Gene Therapy
, vol.20
, pp. 1269-1278
-
-
Low, L.1
Mander, A.2
McCann, K.3
Dearnaley, D.4
Tjelle, T.5
Mathiesen, I.6
Ottensmeier, C.H.7
-
109
-
-
84869086449
-
The extragenic spacer length between the 5′ and 3′ ends of the transgene expression cassette affects transgene silencing from plasmid-based vectors
-
Lu, J., Zhang, F., Xu, S., Fire, A.Z., Kay, M.A., The extragenic spacer length between the 5′ and 3′ ends of the transgene expression cassette affects transgene silencing from plasmid-based vectors. Molecular Therapy 20 (2012), 2111–2119.
-
(2012)
Molecular Therapy
, vol.20
, pp. 2111-2119
-
-
Lu, J.1
Zhang, F.2
Xu, S.3
Fire, A.Z.4
Kay, M.A.5
-
110
-
-
84877015804
-
A mini-intronic plasmid (MIP): A novel robust transgene expression vector in vivo and in vitro
-
Lu, J., Zhang, F., Kay, M.A., A mini-intronic plasmid (MIP): A novel robust transgene expression vector in vivo and in vitro. Molecular Therapy 21 (2013), 954–963.
-
(2013)
Molecular Therapy
, vol.21
, pp. 954-963
-
-
Lu, J.1
Zhang, F.2
Kay, M.A.3
-
111
-
-
0035950987
-
Peptide affinity for MHC influences the phenotype of CD8(+) T cells primed in vivo
-
Ma, H., Kapp, J.a., Peptide affinity for MHC influences the phenotype of CD8(+) T cells primed in vivo. Cellular Immunology 214 (2001), 89–96.
-
(2001)
Cellular Immunology
, vol.214
, pp. 89-96
-
-
Ma, H.1
Kapp, J.A.2
-
112
-
-
0005457558
-
First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response
-
MacGregor, R.R., Boyer, J.D., Ugen, K.E., Lacy, K.E., Gluckman, S.J., Bagarazzi, M.L., Chattergoon, M.A., Baine, Y., Higgins, T.J., Ciccarelli, R.B., et al. First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: Safety and host response. The Journal of Infectious Diseases 178 (1998), 92–100.
-
(1998)
The Journal of Infectious Diseases
, vol.178
, pp. 92-100
-
-
MacGregor, R.R.1
Boyer, J.D.2
Ugen, K.E.3
Lacy, K.E.4
Gluckman, S.J.5
Bagarazzi, M.L.6
Chattergoon, M.A.7
Baine, Y.8
Higgins, T.J.9
Ciccarelli, R.B.10
-
113
-
-
67650463335
-
Prostvac-VF: A vector-based vaccine targeting PSA in prostate cancer
-
Madan, R.A., Arlen, P.M., Mohebtash, M., Hodge, J.W., Gulley, J.L., Prostvac-VF: A vector-based vaccine targeting PSA in prostate cancer. Expert Opinion on Investigational Drugs 18 (2009), 1001–1011.
-
(2009)
Expert Opinion on Investigational Drugs
, vol.18
, pp. 1001-1011
-
-
Madan, R.A.1
Arlen, P.M.2
Mohebtash, M.3
Hodge, J.W.4
Gulley, J.L.5
-
114
-
-
77957787538
-
Therapeutic cancer vaccines in prostate cancer: The paradox of improved survival without changes in time to progression
-
Madan, R.A., Gulley, J.L., Fojo, T., Dahut, W.L., Therapeutic cancer vaccines in prostate cancer: The paradox of improved survival without changes in time to progression. The Oncologist 15 (2010), 969–975.
-
(2010)
The Oncologist
, vol.15
, pp. 969-975
-
-
Madan, R.A.1
Gulley, J.L.2
Fojo, T.3
Dahut, W.L.4
-
115
-
-
84871919467
-
Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level
-
Maniar, L.E.G., Maniar, J.M., Chen, Z.-Y., Lu, J., Fire, A.Z., Kay, M.A., Minicircle DNA vectors achieve sustained expression reflected by active chromatin and transcriptional level. Molecular Therapy 21 (2012), 131–138.
-
(2012)
Molecular Therapy
, vol.21
, pp. 131-138
-
-
Maniar, L.E.G.1
Maniar, J.M.2
Chen, Z.-Y.3
Lu, J.4
Fire, A.Z.5
Kay, M.A.6
-
116
-
-
33748319512
-
Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines
-
McMahan, R.H., McWilliams, J.A., Jordan, K.R., Dow, S.W., Wilson, D.B., Slansky, J.E., Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines. The Journal of Clinical Investigation 116 (2006), 2543–2551.
-
(2006)
The Journal of Clinical Investigation
, vol.116
, pp. 2543-2551
-
-
McMahan, R.H.1
McWilliams, J.A.2
Jordan, K.R.3
Dow, S.W.4
Wilson, D.B.5
Slansky, J.E.6
-
117
-
-
34247119290
-
Prostate cancer immunotherapy
-
McNeel, D.G., Prostate cancer immunotherapy. Current Opinion in Urology 17 (2007), 175–181.
-
(2007)
Current Opinion in Urology
, vol.17
, pp. 175-181
-
-
McNeel, D.G.1
-
119
-
-
10044236665
-
Immune-based therapies for prostate cancer
-
McNeel, D.G., Malkovsky, M., Immune-based therapies for prostate cancer. Immunology Letters 96 (2005), 3–9.
-
(2005)
Immunology Letters
, vol.96
, pp. 3-9
-
-
McNeel, D.G.1
Malkovsky, M.2
-
120
-
-
70249126960
-
Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer
-
McNeel, D.G., Dunphy, E.J., Davies, J.G., Frye, T.P., Johnson, L.E., Staab, M.J., Horvath, D.L., Straus, J., Alberti, D., Marnocha, R., et al. Safety and immunological efficacy of a DNA vaccine encoding prostatic acid phosphatase in patients with stage D0 prostate cancer. Journal of Clinical Oncology 27 (2009), 4047–4054.
-
(2009)
Journal of Clinical Oncology
, vol.27
, pp. 4047-4054
-
-
McNeel, D.G.1
Dunphy, E.J.2
Davies, J.G.3
Frye, T.P.4
Johnson, L.E.5
Staab, M.J.6
Horvath, D.L.7
Straus, J.8
Alberti, D.9
Marnocha, R.10
-
121
-
-
84874838131
-
DNA vaccines for prostate cancer
-
McNeel, D.G., Becker, J.T., Johnson, L.E., Olson, B.M., DNA vaccines for prostate cancer. Current Cancer Therapy Reviews 8 (2012), 254–263.
-
(2012)
Current Cancer Therapy Reviews
, vol.8
, pp. 254-263
-
-
McNeel, D.G.1
Becker, J.T.2
Johnson, L.E.3
Olson, B.M.4
-
122
-
-
84904396423
-
Real-time immune monitoring to guide plasmid DNA vaccination schedule targeting prostatic acid phosphatase in patients with castration-resistant prostate cancer
-
McNeel, D.G., Becker, J.T., Eickhoff, J.C., Johnson, L.E., Bradley, E., Pohlkamp, I.,.. Olson, B.M., Real-time immune monitoring to guide plasmid DNA vaccination schedule targeting prostatic acid phosphatase in patients with castration-resistant prostate cancer. Clinical Cancer Research 20 (2014), 3692–3704.
-
(2014)
Clinical Cancer Research
, vol.20
, pp. 3692-3704
-
-
McNeel, D.G.1
Becker, J.T.2
Eickhoff, J.C.3
Johnson, L.E.4
Bradley, E.5
Pohlkamp, I.6
Olson, B.M.7
-
123
-
-
85018237263
-
DNA vaccine with pembrolizumab elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer (mCRPC)
-
McNeel, D.G., Eickhoff, J., Jeraj, R., Staab, M.J., Straus, J., Rekoske, B., Liu, G., DNA vaccine with pembrolizumab elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer (mCRPC). 2016 national meeting of the Society for Immunotherapy of Cancer, Washington DC, abstract 369, 2016.
-
(2016)
2016 national meeting of the Society for Immunotherapy of Cancer, Washington DC, abstract 369
-
-
McNeel, D.G.1
Eickhoff, J.2
Jeraj, R.3
Staab, M.J.4
Straus, J.5
Rekoske, B.6
Liu, G.7
-
124
-
-
84954042238
-
Tasquinimod in the treatment of castrate-resistant prostate cancer - Current status and future prospects
-
Mehta, A.R., Armstrong, A.J., Tasquinimod in the treatment of castrate-resistant prostate cancer - Current status and future prospects. Therapeutic Advances in Urology 8 (2016), 9–18.
-
(2016)
Therapeutic Advances in Urology
, vol.8
, pp. 9-18
-
-
Mehta, A.R.1
Armstrong, A.J.2
-
125
-
-
0037012726
-
Plasmid vectors with a 5′-hybrid intron facilitate high-level glycoprotein expression in CHO-cells
-
Melcher, R., Grosch, H.-W., Hasilik, A., Plasmid vectors with a 5′-hybrid intron facilitate high-level glycoprotein expression in CHO-cells. Biochimica et Biophysica Acta - Gene Structure and Expression 1575 (2002), 49–53.
-
(2002)
Biochimica et Biophysica Acta - Gene Structure and Expression
, vol.1575
, pp. 49-53
-
-
Melcher, R.1
Grosch, H.-W.2
Hasilik, A.3
-
126
-
-
26444556446
-
Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA
-
Mennuni, C., Calvaruso, F., Facciabene, A., Aurisicchio, L., Storto, M., Scarselli, E.,.. La Monica, N., Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA. International Journal of Cancer 117 (2005), 444–455.
-
(2005)
International Journal of Cancer
, vol.117
, pp. 444-455
-
-
Mennuni, C.1
Calvaruso, F.2
Facciabene, A.3
Aurisicchio, L.4
Storto, M.5
Scarselli, E.6
La Monica, N.7
-
127
-
-
21844444548
-
Immune monitoring in a phase 1 trial of a PSA DNA vaccine in patients with hormone-refractory prostate cancer
-
Miller, A.M., Ozenci, V., Kiessling, R., Pisa, P., Immune monitoring in a phase 1 trial of a PSA DNA vaccine in patients with hormone-refractory prostate cancer. Journal of Immunotherapy 28 (1997), 389–395.
-
(1997)
Journal of Immunotherapy
, vol.28
, pp. 389-395
-
-
Miller, A.M.1
Ozenci, V.2
Kiessling, R.3
Pisa, P.4
-
128
-
-
33750807427
-
CD4 + CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
-
Miller, A.M., Lundberg, K., Ozenci, V., Banham, A.H., Hellstrom, M., Egevad, L., Pisa, P., CD4 + CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients. Journal of Immunology 177 (2006), 7398–7405.
-
(2006)
Journal of Immunology
, vol.177
, pp. 7398-7405
-
-
Miller, A.M.1
Lundberg, K.2
Ozenci, V.3
Banham, A.H.4
Hellstrom, M.5
Egevad, L.6
Pisa, P.7
-
129
-
-
0033948976
-
Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: A phase I/II clinical trial
-
Mincheff, M., Tchakarov, S., Zoubak, S., Loukinov, D., Botev, C., Altankova, I.,.. Meryman, H.T., Naked DNA and adenoviral immunizations for immunotherapy of prostate cancer: A phase I/II clinical trial. European Urology 38 (2000), 208–217.
-
(2000)
European Urology
, vol.38
, pp. 208-217
-
-
Mincheff, M.1
Tchakarov, S.2
Zoubak, S.3
Loukinov, D.4
Botev, C.5
Altankova, I.6
Meryman, H.T.7
-
130
-
-
67651011693
-
Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression
-
Mitsui, M., Nishikawa, M., Zang, L., Ando, M., Hattori, K., Takahashi, Y.,.. Takakura, Y., Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression. The Journal of Gene Medicine 11 (2009), 435–443.
-
(2009)
The Journal of Gene Medicine
, vol.11
, pp. 435-443
-
-
Mitsui, M.1
Nishikawa, M.2
Zang, L.3
Ando, M.4
Hattori, K.5
Takahashi, Y.6
Takakura, Y.7
-
131
-
-
80054694464
-
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells
-
Molon, B., Ugel, S., Del Pozzo, F., Soldani, C., Zilio, S., Avella, D., De Palma, A., Mauri, P., Monegal, A., Rescigno, M., et al. Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. The Journal of Experimental Medicine 208 (2011), 1949–1962.
-
(2011)
The Journal of Experimental Medicine
, vol.208
, pp. 1949-1962
-
-
Molon, B.1
Ugel, S.2
Del Pozzo, F.3
Soldani, C.4
Zilio, S.5
Avella, D.6
De Palma, A.7
Mauri, P.8
Monegal, A.9
Rescigno, M.10
-
132
-
-
85018229156
-
Plasmid transgene expression in vivo: Promoter and tissue variables
-
InTech
-
Morrissey, D., A., S., Rajenderan, S., Casey, G., C., G., Tangney, M., Plasmid transgene expression in vivo: Promoter and tissue variables. Gene therapy - Tools and potential applications, 2013, InTech.
-
(2013)
Gene therapy - Tools and potential applications
-
-
Morrissey, D.1
Rajenderan, S.2
Casey, G.3
Tangney, M.4
-
133
-
-
3242676308
-
Codon optimization of the human papillomavirus 11 (HPV 11) L1 gene leads to increased gene expression and formation of virus-like particles in mammalian epithelial cells
-
Mossadegh, N., Gissmann, L., Müller, M., Zentgraf, H., Alonso, A., Tomakidi, P., Codon optimization of the human papillomavirus 11 (HPV 11) L1 gene leads to increased gene expression and formation of virus-like particles in mammalian epithelial cells. Virology 326 (2004), 57–66.
-
(2004)
Virology
, vol.326
, pp. 57-66
-
-
Mossadegh, N.1
Gissmann, L.2
Müller, M.3
Zentgraf, H.4
Alonso, A.5
Tomakidi, P.6
-
134
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer, R.J., Escudier, B., McDermott, D.F., George, S., Hammers, H.J., Srinivas, S., Tykodi, S.S., Sosman, J.A., Procopio, G., Plimack, E.R., et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. The New England Journal of Medicine 373 (2015), 1803–1813.
-
(2015)
The New England Journal of Medicine
, vol.373
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
George, S.4
Hammers, H.J.5
Srinivas, S.6
Tykodi, S.S.7
Sosman, J.A.8
Procopio, G.9
Plimack, E.R.10
-
135
-
-
84859898868
-
Targeting dendritic cells with antigen via dendritic cell-associated promoters
-
Moulin, V., Morgan, M.E., Eleveld-Trancikova, D., Haanen, J.B.a.G., Wielders, E., Looman, M.W.G.,.. Adema, G.J., Targeting dendritic cells with antigen via dendritic cell-associated promoters. Cancer Gene Therapy 19 (2012), 303–311.
-
(2012)
Cancer Gene Therapy
, vol.19
, pp. 303-311
-
-
Moulin, V.1
Morgan, M.E.2
Eleveld-Trancikova, D.3
Haanen, J.B.A.G.4
Wielders, E.5
Looman, M.W.G.6
Adema, G.J.7
-
136
-
-
84978100766
-
Improved anti-Treg vaccination targeting Foxp3 efficiently decreases regulatory T cells in mice
-
Mousavi Niri, N., Memarnejadian, A., Pilehvar-Soltanahmadi, Y., Agha Sadeghi, M., Mahdavi, M., Kheshtchin, N., Arab, S., Namdar, A., Jadidi, F., Zarghami, N., et al. Improved anti-Treg vaccination targeting Foxp3 efficiently decreases regulatory T cells in mice. Journal of Immunotherapy 39 (2016), 269–275.
-
(2016)
Journal of Immunotherapy
, vol.39
, pp. 269-275
-
-
Mousavi Niri, N.1
Memarnejadian, A.2
Pilehvar-Soltanahmadi, Y.3
Agha Sadeghi, M.4
Mahdavi, M.5
Kheshtchin, N.6
Arab, S.7
Namdar, A.8
Jadidi, F.9
Zarghami, N.10
-
137
-
-
44849094721
-
A novel magnetic approach to enhance the efficacy of cell-based gene therapies
-
Muthana, M., Scott, S.D., Farrow, N., Morrow, F., Murdoch, C., Grubb, S.,.. Lewis, C.E., A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Therapy 15 (2008), 902–910.
-
(2008)
Gene Therapy
, vol.15
, pp. 902-910
-
-
Muthana, M.1
Scott, S.D.2
Farrow, N.3
Morrow, F.4
Murdoch, C.5
Grubb, S.6
Lewis, C.E.7
-
138
-
-
0029912726
-
Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and autoimmunity
-
Naftzger, C., Takechi, Y., Kohda, H., Hara, I., Vijayasaradhi, S., Houghton, A.N., Immune response to a differentiation antigen induced by altered antigen: A study of tumor rejection and autoimmunity. Proceedings of the National Academy of Sciences of the United States of America 93 (1996), 14809–14814.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 14809-14814
-
-
Naftzger, C.1
Takechi, Y.2
Kohda, H.3
Hara, I.4
Vijayasaradhi, S.5
Houghton, A.N.6
-
139
-
-
84857179775
-
CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model
-
Nguyen-Hoai, T., Baldenhofer, G., Ahmed, M.S., Pham-Duc, M., Gries, M., Lipp, M.,.. Westermann, J., CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model. The Journal of Gene Medicine 14 (2012), 128–137.
-
(2012)
The Journal of Gene Medicine
, vol.14
, pp. 128-137
-
-
Nguyen-Hoai, T.1
Baldenhofer, G.2
Ahmed, M.S.3
Pham-Duc, M.4
Gries, M.5
Lipp, M.6
Westermann, J.7
-
140
-
-
84869222557
-
CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: Improved vaccine efficacy and a role for B cells as APC
-
Nguyen-Hoai, T., Hohn, O., Vu, M.D., Baldenhofer, G., Sayed Ahmed, M.S., Dörken, B.,.. Westermann, J., CCL19 as an adjuvant for intradermal gene gun immunization in a Her2/neu mouse tumor model: Improved vaccine efficacy and a role for B cells as APC. Cancer Gene Therapy 19 (2012), 880–887.
-
(2012)
Cancer Gene Therapy
, vol.19
, pp. 880-887
-
-
Nguyen-Hoai, T.1
Hohn, O.2
Vu, M.D.3
Baldenhofer, G.4
Sayed Ahmed, M.S.5
Dörken, B.6
Westermann, J.7
-
141
-
-
68349144574
-
Targeting anti-tumor DNA vaccines to dendritic cells via a short CD11c promoter sequence
-
Ni, J., Nolte, B., Arnold, A., Fournier, P., Schirrmacher, V., Targeting anti-tumor DNA vaccines to dendritic cells via a short CD11c promoter sequence. Vaccine 27 (2009), 5480–5487.
-
(2009)
Vaccine
, vol.27
, pp. 5480-5487
-
-
Ni, J.1
Nolte, B.2
Arnold, A.3
Fournier, P.4
Schirrmacher, V.5
-
142
-
-
84872317979
-
Innate immune responses to DNA viruses
-
Nie, Y., Wang, Y.-Y., Innate immune responses to DNA viruses. Protein & Cell 4 (2013), 1–7.
-
(2013)
Protein & Cell
, vol.4
, pp. 1-7
-
-
Nie, Y.1
Wang, Y.-Y.2
-
143
-
-
77952223624
-
Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors
-
Olsson, A., Björk, A., Vallon-Christersson, J., Isaacs, J.T., Leanderson, T., Tasquinimod (ABR-215050), a quinoline-3-carboxamide anti-angiogenic agent, modulates the expression of thrombospondin-1 in human prostate tumors. Molecular Cancer, 9, 2010, 107.
-
(2010)
Molecular Cancer
, vol.9
, pp. 107
-
-
Olsson, A.1
Björk, A.2
Vallon-Christersson, J.3
Isaacs, J.T.4
Leanderson, T.5
-
144
-
-
79952187756
-
Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I
-
Osborn, M.J., McElmurry, R.T., Lees, C.J., DeFeo, A.P., Chen, Z.-Y., Kay, M.A.,.. Blazar, B.R., Minicircle DNA-based gene therapy coupled with immune modulation permits long-term expression of α-L-iduronidase in mice with mucopolysaccharidosis type I. Molecular Therapy 19 (2011), 450–460.
-
(2011)
Molecular Therapy
, vol.19
, pp. 450-460
-
-
Osborn, M.J.1
McElmurry, R.T.2
Lees, C.J.3
DeFeo, A.P.4
Chen, Z.-Y.5
Kay, M.A.6
Blazar, B.R.7
-
145
-
-
84959432867
-
Breaking bad habits: Targeting MDSCs to alleviate immunosuppression in prostate cancer
-
Pal, S.K., Kortylewski, M., Breaking bad habits: Targeting MDSCs to alleviate immunosuppression in prostate cancer. OncoImmunology, 5, 2015, e1078060.
-
(2015)
OncoImmunology
, vol.5
-
-
Pal, S.K.1
Kortylewski, M.2
-
146
-
-
3042786281
-
Promoters and control elements: Designing expression cassettes for gene therapy
-
Papadakis, E., Nicklin, S., Baker, A., White, S., Promoters and control elements: Designing expression cassettes for gene therapy. Current Gene Therapy 4 (2004), 89–113.
-
(2004)
Current Gene Therapy
, vol.4
, pp. 89-113
-
-
Papadakis, E.1
Nicklin, S.2
Baker, A.3
White, S.4
-
147
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll, D.M., The blockade of immune checkpoints in cancer immunotherapy. Nature Reviews. Cancer 12 (2012), 252–264.
-
(2012)
Nature Reviews. Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
148
-
-
84880428467
-
Alpha emitter radium-223 and survival in metastatic prostate cancer
-
Parker, C., Nilsson, S., Heinrich, D., Helle, S.I., O'Sullivan, J.M., Fosså, S.D., Chodacki, A., Wiechno, P., Logue, J., Seke, M., et al. Alpha emitter radium-223 and survival in metastatic prostate cancer. The New England Journal of Medicine 369 (2013), 213–223.
-
(2013)
The New England Journal of Medicine
, vol.369
, pp. 213-223
-
-
Parker, C.1
Nilsson, S.2
Heinrich, D.3
Helle, S.I.4
O'Sullivan, J.M.5
Fosså, S.D.6
Chodacki, A.7
Wiechno, P.8
Logue, J.9
Seke, M.10
-
149
-
-
4344672484
-
A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer
-
Pavlenko, M., Roos, A.-K., Lundqvist, A., Palmborg, A., Miller, A.M., Ozenci, V., Bergman, B., Egevad, L., Hellström, M., Kiessling, R., et al. A phase I trial of DNA vaccination with a plasmid expressing prostate-specific antigen in patients with hormone-refractory prostate cancer. British Journal of Cancer 91 (2004), 688–694.
-
(2004)
British Journal of Cancer
, vol.91
, pp. 688-694
-
-
Pavlenko, M.1
Roos, A.-K.2
Lundqvist, A.3
Palmborg, A.4
Miller, A.M.5
Ozenci, V.6
Bergman, B.7
Egevad, L.8
Hellström, M.9
Kiessling, R.10
-
150
-
-
34447620460
-
Priming of CD8 + T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice
-
Pavlenko, M., Leder, C., Moreno, S., Levitsky, V., Pisa, P., Priming of CD8 + T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice. Vaccine 25 (2007), 6341–6347.
-
(2007)
Vaccine
, vol.25
, pp. 6341-6347
-
-
Pavlenko, M.1
Leder, C.2
Moreno, S.3
Levitsky, V.4
Pisa, P.5
-
151
-
-
84892747374
-
The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34 + cells in patients with multiple myeloma
-
Peled, A., Abraham, M., Avivi, I., Rowe, J.M., Beider, K., Wald, H., Tiomkin, L., Ribakovsky, L., Riback, Y., Ramati, Y., et al. The high-affinity CXCR4 antagonist BKT140 is safe and induces a robust mobilization of human CD34 + cells in patients with multiple myeloma. Clinical Cancer Research 20 (2014), 469–479.
-
(2014)
Clinical Cancer Research
, vol.20
, pp. 469-479
-
-
Peled, A.1
Abraham, M.2
Avivi, I.3
Rowe, J.M.4
Beider, K.5
Wald, H.6
Tiomkin, L.7
Ribakovsky, L.8
Riback, Y.9
Ramati, Y.10
-
152
-
-
3442881731
-
SWOG 99-16: Randomized phase III trial of docetaxel (D)/estramustine (E) versus mitoxantrone (M)/prednisone (p) in men with androgen-independent prostate cancer (AIPCA)
-
Petrylak, D.P., Tangen, C., Hussain, M., Lara, P.N., Jones, J., Talpin, M.E.,.. Crawford, E.D., SWOG 99-16: Randomized phase III trial of docetaxel (D)/estramustine (E) versus mitoxantrone (M)/prednisone (p) in men with androgen-independent prostate cancer (AIPCA). ASCO meet. Abstr. 22, 2004, 3.
-
(2004)
ASCO meet. Abstr. 22
, pp. 3
-
-
Petrylak, D.P.1
Tangen, C.2
Hussain, M.3
Lara, P.N.4
Jones, J.5
Talpin, M.E.6
Crawford, E.D.7
-
153
-
-
81355160561
-
Magnetically enhanced nucleic acid delivery. Ten years of magnetofection—Progress and prospects
-
Plank, C., Zelphati, O., Mykhaylyk, O., Magnetically enhanced nucleic acid delivery. Ten years of magnetofection—Progress and prospects. Advanced Drug Delivery Reviews 63 (2011), 1300–1331.
-
(2011)
Advanced Drug Delivery Reviews
, vol.63
, pp. 1300-1331
-
-
Plank, C.1
Zelphati, O.2
Mykhaylyk, O.3
-
154
-
-
0032555907
-
Predominant role for directly transfected dendritic cells in antigen presentation to CD8 + T cells after gene gun immunization
-
Porgador, A., Irvine, K.R., Iwasaki, A., Barber, B.H., Restifo, N.P., Germain, R.N., Predominant role for directly transfected dendritic cells in antigen presentation to CD8 + T cells after gene gun immunization. The Journal of Experimental Medicine 188 (1998), 1075–1082.
-
(1998)
The Journal of Experimental Medicine
, vol.188
, pp. 1075-1082
-
-
Porgador, A.1
Irvine, K.R.2
Iwasaki, A.3
Barber, B.H.4
Restifo, N.P.5
Germain, R.N.6
-
155
-
-
0033526309
-
Natural history of progression after PSA elevation following radical prostatectomy
-
Pound, C.R., Partin, A.W., Eisenberger, M.A., Chan, D.W., Pearson, J.D., Walsh, P.C., Natural history of progression after PSA elevation following radical prostatectomy. JAMA 281 (1999), 1591–1597.
-
(1999)
JAMA
, vol.281
, pp. 1591-1597
-
-
Pound, C.R.1
Partin, A.W.2
Eisenberger, M.A.3
Chan, D.W.4
Pearson, J.D.5
Walsh, P.C.6
-
156
-
-
84946571774
-
Regulatory T cells modulate DNA vaccine immunogenicity at early time via functional CD4(+) T cells and antigen duration
-
Qin, L., Jiang, G., Han, J., Letvin, N.L., Regulatory T cells modulate DNA vaccine immunogenicity at early time via functional CD4(+) T cells and antigen duration. Frontiers in Immunology, 6, 2015, 510.
-
(2015)
Frontiers in Immunology
, vol.6
, pp. 510
-
-
Qin, L.1
Jiang, G.2
Han, J.3
Letvin, N.L.4
-
157
-
-
0029989258
-
B lymphocytes secrete antigen-presenting vesicles
-
Raposo, G., Nijman, H.W., Stoorvogel, W., Liejendekker, R., Harding, C.V., Melief, C.J., Geuze, H.J., B lymphocytes secrete antigen-presenting vesicles. The Journal of Experimental Medicine 183 (1996), 1161–1172.
-
(1996)
The Journal of Experimental Medicine
, vol.183
, pp. 1161-1172
-
-
Raposo, G.1
Nijman, H.W.2
Stoorvogel, W.3
Liejendekker, R.4
Harding, C.V.5
Melief, C.J.6
Geuze, H.J.7
-
158
-
-
84892149853
-
An update on PYRIN domain-containing pattern recognition receptors: From immunity to pathology
-
Ratsimandresy, R.A., Dorfleutner, A., Stehlik, C., An update on PYRIN domain-containing pattern recognition receptors: From immunity to pathology. Molecular Innate Immunity, 4, 2013, 440.
-
(2013)
Molecular Innate Immunity
, vol.4
, pp. 440
-
-
Ratsimandresy, R.A.1
Dorfleutner, A.2
Stehlik, C.3
-
159
-
-
84950283228
-
PD-1 or PD-L1 blockade restores antitumor efficacy following SSX2 epitope-modified DNA vaccine immunization
-
Rekoske, B.T., Smith, H.A., Olson, B.M., Maricque, B.B., McNeel, D.G., PD-1 or PD-L1 blockade restores antitumor efficacy following SSX2 epitope-modified DNA vaccine immunization. Cancer Immunology Research 3 (2015), 946–955.
-
(2015)
Cancer Immunology Research
, vol.3
, pp. 946-955
-
-
Rekoske, B.T.1
Smith, H.A.2
Olson, B.M.3
Maricque, B.B.4
McNeel, D.G.5
-
160
-
-
84976528844
-
Antitumor vaccination of prostate cancer patients elicits PD-1/PD-L1 regulated antigen-specific immune responses
-
Rekoske, B.T., Olson, B.M., McNeel, D.G., Antitumor vaccination of prostate cancer patients elicits PD-1/PD-L1 regulated antigen-specific immune responses. OncoImmunology, 5, 2016, e1165377.
-
(2016)
OncoImmunology
, vol.5
-
-
Rekoske, B.T.1
Olson, B.M.2
McNeel, D.G.3
-
161
-
-
34250739823
-
Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo
-
Riu, E., Chen, Z.-Y., Xu, H., He, C.-Y., Kay, M.A., Histone modifications are associated with the persistence or silencing of vector-mediated transgene expression in vivo. Molecular Therapy: The Journal of the American Society of Gene Therapy 15 (2007), 1348–1355.
-
(2007)
Molecular Therapy: The Journal of the American Society of Gene Therapy
, vol.15
, pp. 1348-1355
-
-
Riu, E.1
Chen, Z.-Y.2
Xu, H.3
He, C.-Y.4
Kay, M.A.5
-
162
-
-
84896818399
-
Regulation of immune responses by extracellular vesicles
-
Robbins, P.D., Morelli, A.E., Regulation of immune responses by extracellular vesicles. Nature Reviews. Immunology 14 (2014), 195–208.
-
(2014)
Nature Reviews. Immunology
, vol.14
, pp. 195-208
-
-
Robbins, P.D.1
Morelli, A.E.2
-
163
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
Robert, C., Thomas, L., Bondarenko, I., O'Day, S., Weber, J., Garbe, C., Lebbe, C., Baurain, J.-F., Testori, A., Grob, J.-J., et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. The New England Journal of Medicine 364 (2011), 2517–2526.
-
(2011)
The New England Journal of Medicine
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
Lebbe, C.7
Baurain, J.-F.8
Testori, A.9
Grob, J.-J.10
-
164
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert, C., Long, G.V., Brady, B., Dutriaux, C., Maio, M., Mortier, L., Hassel, J.C., Rutkowski, P., McNeil, C., Kalinka-Warzocha, E., et al. Nivolumab in previously untreated melanoma without BRAF mutation. The New England Journal of Medicine 372 (2015), 320–330.
-
(2015)
The New England Journal of Medicine
, vol.372
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
Dutriaux, C.4
Maio, M.5
Mortier, L.6
Hassel, J.C.7
Rutkowski, P.8
McNeil, C.9
Kalinka-Warzocha, E.10
-
165
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
Robert, C., Schachter, J., Long, G.V., Arance, A., Grob, J.J., Mortier, L., Daud, A., Carlino, M.S., McNeil, C., Lotem, M., et al. Pembrolizumab versus ipilimumab in advanced melanoma. The New England Journal of Medicine 372 (2015), 2521–2532.
-
(2015)
The New England Journal of Medicine
, vol.372
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
Arance, A.4
Grob, J.J.5
Mortier, L.6
Daud, A.7
Carlino, M.S.8
McNeil, C.9
Lotem, M.10
-
166
-
-
77953438206
-
Erbb2 DNA vaccine combined with regulatory T cell deletion enhances antibody response and reveals latent low-avidity T cells: Potential and limits of its therapeutic efficacy
-
Rolla, S., Ria, F., Occhipinti, S., Di Sante, G., Iezzi, M., Spadaro, M., Nicolo, C., Ambrosino, E., Merighi, I.F., Musiani, P., et al. Erbb2 DNA vaccine combined with regulatory T cell deletion enhances antibody response and reveals latent low-avidity T cells: Potential and limits of its therapeutic efficacy. Journal of Immunology 184 (2010), 6124–6132.
-
(2010)
Journal of Immunology
, vol.184
, pp. 6124-6132
-
-
Rolla, S.1
Ria, F.2
Occhipinti, S.3
Di Sante, G.4
Iezzi, M.5
Spadaro, M.6
Nicolo, C.7
Ambrosino, E.8
Merighi, I.F.9
Musiani, P.10
-
167
-
-
70349644484
-
Skin electroporation: Effects on transgene expression, DNA persistence and local tissue environment
-
Roos, A.-K., Eriksson, F., Timmons, J.A., Gerhardt, J., Nyman, U., Gudmundsdotter, L.,.. Pisa, P., Skin electroporation: Effects on transgene expression, DNA persistence and local tissue environment. PloS One, 4, 2009, e7226.
-
(2009)
PloS One
, vol.4
-
-
Roos, A.-K.1
Eriksson, F.2
Timmons, J.A.3
Gerhardt, J.4
Nyman, U.5
Gudmundsdotter, L.6
Pisa, P.7
-
168
-
-
84858202940
-
Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression
-
Roth, F., De La Fuente, A.C., Vella, J.L., Zoso, A., Inverardi, L., Serafini, P., Bronte, V., Apolloni, E., Cabrelle, A., Ronca, R., et al. Aptamer-mediated blockade of IL4Rα triggers apoptosis of MDSCs and limits tumor progression. Cancer Research 72 (2012), 1373–1383.
-
(2012)
Cancer Research
, vol.72
, pp. 1373-1383
-
-
Roth, F.1
De La Fuente, A.C.2
Vella, J.L.3
Zoso, A.4
Inverardi, L.5
Serafini, P.6
Bronte, V.7
Apolloni, E.8
Cabrelle, A.9
Ronca, R.10
-
169
-
-
84856869561
-
Technologies for enhanced efficacy of DNA vaccines
-
Saade, F., Petrovsky, N., Technologies for enhanced efficacy of DNA vaccines. Expert Review of Vaccines 11 (2012), 189–209.
-
(2012)
Expert Review of Vaccines
, vol.11
, pp. 189-209
-
-
Saade, F.1
Petrovsky, N.2
-
170
-
-
84905235486
-
Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine
-
Sajadian, A., Tabarraei, A., Soleimanjahi, H., Fotouhi, F., Gorji, A., Ghaemi, A., Comparing the effect of Toll-like receptor agonist adjuvants on the efficiency of a DNA vaccine. Archives of Virology 159 (2014), 1951–1960.
-
(2014)
Archives of Virology
, vol.159
, pp. 1951-1960
-
-
Sajadian, A.1
Tabarraei, A.2
Soleimanjahi, H.3
Fotouhi, F.4
Gorji, A.5
Ghaemi, A.6
-
171
-
-
84893769637
-
Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas
-
Sakamaki, I., Kwak, L.W., Cha, S., Yi, Q., Lerman, B., Chen, J.,.. Qin, H., Lenalidomide enhances the protective effect of a therapeutic vaccine and reverses immune suppression in mice bearing established lymphomas. Leukemia 28 (2014), 329–337.
-
(2014)
Leukemia
, vol.28
, pp. 329-337
-
-
Sakamaki, I.1
Kwak, L.W.2
Cha, S.3
Yi, Q.4
Lerman, B.5
Chen, J.6
Qin, H.7
-
172
-
-
84923364836
-
MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity
-
Salama, A., Fichou, N., Allard, M., Dubreil, L., De Beaurepaire, L., Viel, A.,.. Bach, J.-M., MicroRNA-29b modulates innate and antigen-specific immune responses in mouse models of autoimmunity. PloS One, 9, 2014, e106153.
-
(2014)
PloS One
, vol.9
-
-
Salama, A.1
Fichou, N.2
Allard, M.3
Dubreil, L.4
De Beaurepaire, L.5
Viel, A.6
Bach, J.-M.7
-
173
-
-
84977103128
-
Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab
-
Santegoets, S.J., Stam, A.G., Lougheed, S.M., Gall, H., Jooss, K., Sacks, N., Hege, K., Lowy, I., Scheper, R.J., Gerritsen, W.R., et al. Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab. Journal for Immunotherapy of Cancer, 2, 2014, 31.
-
(2014)
Journal for Immunotherapy of Cancer
, vol.2
, pp. 31
-
-
Santegoets, S.J.1
Stam, A.G.2
Lougheed, S.M.3
Gall, H.4
Jooss, K.5
Sacks, N.6
Hege, K.7
Lowy, I.8
Scheper, R.J.9
Gerritsen, W.R.10
-
174
-
-
77956689533
-
Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3
-
(80-.)
-
Sasai, M., Linehan, M.M., Iwasaki, A., Bifurcation of Toll-like receptor 9 signaling by adaptor protein 3. Science 329 (2010), 1530–1534 (80-.).
-
(2010)
Science
, vol.329
, pp. 1530-1534
-
-
Sasai, M.1
Linehan, M.M.2
Iwasaki, A.3
-
175
-
-
0036284363
-
Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors
-
Sasaki, S., Amara, R.R., Yeow, W.-S., Pitha, P.M., Robinson, H.L., Regulation of DNA-raised immune responses by cotransfected interferon regulatory factors. Journal of Virology 76 (2002), 6652–6659.
-
(2002)
Journal of Virology
, vol.76
, pp. 6652-6659
-
-
Sasaki, S.1
Amara, R.R.2
Yeow, W.-S.3
Pitha, P.M.4
Robinson, H.L.5
-
176
-
-
84866770294
-
Increased survival with enzalutamide in prostate cancer after chemotherapy
-
Scher, H.I., Fizazi, K., Saad, F., Taplin, M.-E., Sternberg, C.N., Miller, K., de Wit, R., Mulders, P., Chi, K.N., Shore, N.D., et al. Increased survival with enzalutamide in prostate cancer after chemotherapy. The New England Journal of Medicine 367 (2012), 1187–1197.
-
(2012)
The New England Journal of Medicine
, vol.367
, pp. 1187-1197
-
-
Scher, H.I.1
Fizazi, K.2
Saad, F.3
Taplin, M.-E.4
Sternberg, C.N.5
Miller, K.6
de Wit, R.7
Mulders, P.8
Chi, K.N.9
Shore, N.D.10
-
177
-
-
85047695405
-
Magnetofection: Enhancing and targeting gene delivery by magnetic force in vitro and in vivo
-
Scherer, F., Anton, M., Schillinger, U., Henke, J., Bergemann, C., Krüger, A.,.. Plank, C., Magnetofection: Enhancing and targeting gene delivery by magnetic force in vitro and in vivo. Gene Therapy 9 (2002), 102–109.
-
(2002)
Gene Therapy
, vol.9
, pp. 102-109
-
-
Scherer, F.1
Anton, M.2
Schillinger, U.3
Henke, J.4
Bergemann, C.5
Krüger, A.6
Plank, C.7
-
178
-
-
84880294344
-
Vemurafenib reverses immunosuppression by myeloid derived suppressor cells
-
Schilling, B., Sucker, A., Griewank, K., Zhao, F., Weide, B., Görgens, A.,.. Paschen, A., Vemurafenib reverses immunosuppression by myeloid derived suppressor cells. International Journal of Cancer 133 (2013), 1653–1663.
-
(2013)
International Journal of Cancer
, vol.133
, pp. 1653-1663
-
-
Schilling, B.1
Sucker, A.2
Griewank, K.3
Zhao, F.4
Weide, B.5
Görgens, A.6
Paschen, A.7
-
179
-
-
3242656979
-
CpG motifs are efficient adjuvants for DNA cancer vaccines
-
Schneeberger, A., Wagner, C., Zemann, A., Lührs, P., Kutil, R., Goos, M.,.. Wagner, S.N., CpG motifs are efficient adjuvants for DNA cancer vaccines. The Journal of Investigative Dermatology 123 (2004), 371–379.
-
(2004)
The Journal of Investigative Dermatology
, vol.123
, pp. 371-379
-
-
Schneeberger, A.1
Wagner, C.2
Zemann, A.3
Lührs, P.4
Kutil, R.5
Goos, M.6
Wagner, S.N.7
-
180
-
-
84920506722
-
DNA mediated vaccines delivery through nanoparticles
-
Shah, M.A.A., Ali, Z., Ahmad, R., Qadri, I., Fatima, K., He, N., DNA mediated vaccines delivery through nanoparticles. Journal of Nanoscience and Nanotechnology 15 (2015), 41–53.
-
(2015)
Journal of Nanoscience and Nanotechnology
, vol.15
, pp. 41-53
-
-
Shah, M.A.A.1
Ali, Z.2
Ahmad, R.3
Qadri, I.4
Fatima, K.5
He, N.6
-
181
-
-
79955756681
-
Innate immune sensing of DNA
-
Sharma, S., Fitzgerald, K.A., Innate immune sensing of DNA. PLoS Pathogens, 7, 2011, e1001310.
-
(2011)
PLoS Pathogens
, vol.7
-
-
Sharma, S.1
Fitzgerald, K.A.2
-
182
-
-
84962290319
-
Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models
-
Shen, L., Sundstedt, A., Ciesielski, M., Miles, K.M., Celander, M., Adelaiye, R., Orillion, A., Ciamporcero, E., Ramakrishnan, S., Ellis, L., et al. Tasquinimod modulates suppressive myeloid cells and enhances cancer immunotherapies in murine models. Cancer Immunology Research 3 (2015), 136–148.
-
(2015)
Cancer Immunology Research
, vol.3
, pp. 136-148
-
-
Shen, L.1
Sundstedt, A.2
Ciesielski, M.3
Miles, K.M.4
Celander, M.5
Adelaiye, R.6
Orillion, A.7
Ciamporcero, E.8
Ramakrishnan, S.9
Ellis, L.10
-
183
-
-
61549091187
-
Contribution of IRF-3 mediated IFNbeta production to DNA vaccine dependent cellular immune responses
-
Shirota, H., Petrenko, L., Hattori, T., Klinman, D.M., Contribution of IRF-3 mediated IFNbeta production to DNA vaccine dependent cellular immune responses. Vaccine 27 (2009), 2144–2149.
-
(2009)
Vaccine
, vol.27
, pp. 2144-2149
-
-
Shirota, H.1
Petrenko, L.2
Hattori, T.3
Klinman, D.M.4
-
184
-
-
84954400636
-
Cancer statistics, 2016
-
Siegel, R.L., Miller, K.D., Jemal, A., Cancer statistics, 2016. CA: a Cancer Journal for Clinicians 66 (2016), 7–30.
-
(2016)
CA: a Cancer Journal for Clinicians
, vol.66
, pp. 7-30
-
-
Siegel, R.L.1
Miller, K.D.2
Jemal, A.3
-
185
-
-
84982752093
-
PD-1 expression conditions T cell avidity within an antigen-specific repertoire
-
Simon, S., Vignard, V., Florenceau, L., Dreno, B., Khammari, A., Lang, F., Labarriere, N., PD-1 expression conditions T cell avidity within an antigen-specific repertoire. OncoImmunology, 5, 2015, e1104448.
-
(2015)
OncoImmunology
, vol.5
-
-
Simon, S.1
Vignard, V.2
Florenceau, L.3
Dreno, B.4
Khammari, A.5
Lang, F.6
Labarriere, N.7
-
186
-
-
13044253477
-
Carbohydrate vaccines in cancer: Immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man
-
Slovin, S.F., Ragupathi, G., Adluri, S., Ungers, G., Terry, K., Kim, S., Spassova, M., Bornmann, W.G., Fazzari, M., Dantis, L., et al. Carbohydrate vaccines in cancer: Immunogenicity of a fully synthetic globo H hexasaccharide conjugate in man. Proceedings of the National Academy of Sciences of the United States of America 96 (1999), 5710–5715.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 5710-5715
-
-
Slovin, S.F.1
Ragupathi, G.2
Adluri, S.3
Ungers, G.4
Terry, K.5
Kim, S.6
Spassova, M.7
Bornmann, W.G.8
Fazzari, M.9
Dantis, L.10
-
187
-
-
79953700040
-
A xenogeneic PSMA DNA vaccine for patients (pts) with non-castrate metastatic (NCMPC) and castrate metastatic prostate cancer (CMPC)—A phase I trial of proof of principle
-
Slovin, S., Gregor, P., Wolchok, J., Pedraza, A., Orlandi, F., Jefferson, M., Jefferson, M., Fernandez, C., Rudolph, J., Houghton, A., et al. A xenogeneic PSMA DNA vaccine for patients (pts) with non-castrate metastatic (NCMPC) and castrate metastatic prostate cancer (CMPC)—A phase I trial of proof of principle. ASCO meet. Abstr. 25, 2007, 3073.
-
(2007)
ASCO meet. Abstr. 25
, pp. 3073
-
-
Slovin, S.1
Gregor, P.2
Wolchok, J.3
Pedraza, A.4
Orlandi, F.5
Jefferson, M.6
Jefferson, M.7
Fernandez, C.8
Rudolph, J.9
Houghton, A.10
-
188
-
-
80052968146
-
Vaccines targeting the cancer-testis antigen SSX-2 elicit HLA-A2 epitope-specific cytolytic T cells
-
Smith, H.A., McNeel, D.G., Vaccines targeting the cancer-testis antigen SSX-2 elicit HLA-A2 epitope-specific cytolytic T cells. Journal of Immunotherapy 34 (2011), 569–580.
-
(2011)
Journal of Immunotherapy
, vol.34
, pp. 569-580
-
-
Smith, H.A.1
McNeel, D.G.2
-
189
-
-
84895858697
-
DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8 + T-cell immune responses
-
Smith, H.a., Rekoske, B.T., McNeel, D.G., DNA vaccines encoding altered peptide ligands for SSX2 enhance epitope-specific CD8 + T-cell immune responses. Vaccine 32 (2014), 1707–1715.
-
(2014)
Vaccine
, vol.32
, pp. 1707-1715
-
-
Smith, H.A.1
Rekoske, B.T.2
McNeel, D.G.3
-
190
-
-
84863991235
-
Myeloid suppressor cell depletion augments antitumor activity in lung cancer
-
Srivastava, M.K., Zhu, L., Harris-White, M., Kar, U.K., Kar, U., Huang, M., Johnson, M.F., Lee, J.M., Elashoff, D., Strieter, R., et al. Myeloid suppressor cell depletion augments antitumor activity in lung cancer. PloS One, 7, 2012, e40677.
-
(2012)
PloS One
, vol.7
-
-
Srivastava, M.K.1
Zhu, L.2
Harris-White, M.3
Kar, U.K.4
Kar, U.5
Huang, M.6
Johnson, M.F.7
Lee, J.M.8
Elashoff, D.9
Strieter, R.10
-
191
-
-
0035137604
-
CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes
-
Stan, A.C., Casares, S., Brumeanu, T.D., Klinman, D.M., Bona, C.A., CpG motifs of DNA vaccines induce the expression of chemokines and MHC class II molecules on myocytes. European Journal of Immunology 31 (2001), 301–310.
-
(2001)
European Journal of Immunology
, vol.31
, pp. 301-310
-
-
Stan, A.C.1
Casares, S.2
Brumeanu, T.D.3
Klinman, D.M.4
Bona, C.A.5
-
192
-
-
84873711885
-
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway
-
Sun, L., Wu, J., Du, F., Chen, X., Chen, Z.J., Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339 (2012), 786–791.
-
(2012)
Science
, vol.339
, pp. 786-791
-
-
Sun, L.1
Wu, J.2
Du, F.3
Chen, X.4
Chen, Z.J.5
-
193
-
-
84920374073
-
Identification of Aim2 as a sensor for DNA vaccines
-
Suschak, J.J., Wang, S., Fitzgerald, K.A., Lu, S., Identification of Aim2 as a sensor for DNA vaccines. Journal of Immunology 194 (2014), 630–636.
-
(2014)
Journal of Immunology
, vol.194
, pp. 630-636
-
-
Suschak, J.J.1
Wang, S.2
Fitzgerald, K.A.3
Lu, S.4
-
194
-
-
84953284810
-
A cGAS-independent STING/IRF7 pathway mediates the immunogenicity of DNA vaccines
-
Suschak, J.J., Wang, S., Fitzgerald, K.A., Lu, S., A cGAS-independent STING/IRF7 pathway mediates the immunogenicity of DNA vaccines. Journal of Immunology (Baltimore, Md.: 1950) 196 (2016), 310–316.
-
(2016)
Journal of Immunology (Baltimore, Md.: 1950)
, vol.196
, pp. 310-316
-
-
Suschak, J.J.1
Wang, S.2
Fitzgerald, K.A.3
Lu, S.4
-
195
-
-
84860133344
-
Increased CD8 + T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells
-
Tang, S., Moore, M.L., Grayson, J.M., Dubey, P., Increased CD8 + T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells. Cancer Research 72 (2012), 1975–1985.
-
(2012)
Cancer Research
, vol.72
, pp. 1975-1985
-
-
Tang, S.1
Moore, M.L.2
Grayson, J.M.3
Dubey, P.4
-
196
-
-
0036676445
-
Exosomes: Composition, biogenesis and function
-
Théry, C., Zitvogel, L., Amigorena, S., Exosomes: Composition, biogenesis and function. Nature Reviews. Immunology 2 (2002), 569–579.
-
(2002)
Nature Reviews. Immunology
, vol.2
, pp. 569-579
-
-
Théry, C.1
Zitvogel, L.2
Amigorena, S.3
-
197
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S.L., Hodi, F.S., Brahmer, J.R., Gettinger, S.N., Smith, D.C., McDermott, D.F., Powderly, J.D., Carvajal, R.D., Sosman, J.A., Atkins, M.B., et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. The New England Journal of Medicine 366 (2012), 2443–2454.
-
(2012)
The New England Journal of Medicine
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
-
198
-
-
0034578390
-
Priming of CTL responses by DNA vaccines: Direct transfection of antigen presenting cells versus cross-priming
-
Ulmer, J.B., Otten, G.R., Priming of CTL responses by DNA vaccines: Direct transfection of antigen presenting cells versus cross-priming. Developmental Biology (Basel) 104 (2000), 9–14.
-
(2000)
Developmental Biology (Basel)
, vol.104
, pp. 9-14
-
-
Ulmer, J.B.1
Otten, G.R.2
-
199
-
-
0027411456
-
Heterologous protection against influenza by injection of DNA encoding a viral protein
-
Ulmer, J.B., Donnelly, J.J., Parker, S.E., Rhodes, G.H., Felgner, P.L., Dwarki, V.J.,.. Friedman, A., Heterologous protection against influenza by injection of DNA encoding a viral protein. Science 259 (1993), 1745–1749.
-
(1993)
Science
, vol.259
, pp. 1745-1749
-
-
Ulmer, J.B.1
Donnelly, J.J.2
Parker, S.E.3
Rhodes, G.H.4
Felgner, P.L.5
Dwarki, V.J.6
Friedman, A.7
-
200
-
-
79953809082
-
Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier
-
Un, K., Kawakami, S., Suzuki, R., Maruyama, K., Yamashita, F., Hashida, M., Suppression of melanoma growth and metastasis by DNA vaccination using an ultrasound-responsive and mannose-modified gene carrier. Molecular Pharmaceutics 8 (2011), 543–554.
-
(2011)
Molecular Pharmaceutics
, vol.8
, pp. 543-554
-
-
Un, K.1
Kawakami, S.2
Suzuki, R.3
Maruyama, K.4
Yamashita, F.5
Hashida, M.6
-
201
-
-
77958140656
-
IFI16 is an innate immune sensor for intracellular DNA
-
Unterholzner, L., Keating, S.E., Baran, M., Horan, K.A., Jensen, S.B., Sharma, S., Sirois, C.M., Jin, T., Latz, E., Xiao, T.S., et al. IFI16 is an innate immune sensor for intracellular DNA. Nature Immunology 11 (2010), 997–1004.
-
(2010)
Nature Immunology
, vol.11
, pp. 997-1004
-
-
Unterholzner, L.1
Keating, S.E.2
Baran, M.3
Horan, K.A.4
Jensen, S.B.5
Sharma, S.6
Sirois, C.M.7
Jin, T.8
Latz, E.9
Xiao, T.S.10
-
202
-
-
34249302620
-
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells
-
Valadi, H., Ekström, K., Bossios, A., Sjöstrand, M., Lee, J.J., Lötvall, J.O., Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nature Cell Biology 9 (2007), 654–659.
-
(2007)
Nature Cell Biology
, vol.9
, pp. 654-659
-
-
Valadi, H.1
Ekström, K.2
Bossios, A.3
Sjöstrand, M.4
Lee, J.J.5
Lötvall, J.O.6
-
203
-
-
84860436621
-
Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: A phase 1 dose-escalation trial
-
van den Eertwegh, A.J.M., Versluis, J., van den Berg, H.P., Santegoets, S.J.A.M., van Moorselaar, R.J.A., van der Sluis, T.M., Gall, H.E., Harding, T.C., Jooss, K., Lowy, I., et al. Combined immunotherapy with granulocyte-macrophage colony-stimulating factor-transduced allogeneic prostate cancer cells and ipilimumab in patients with metastatic castration-resistant prostate cancer: A phase 1 dose-escalation trial. The Lancet Oncology 13 (2012), 509–517.
-
(2012)
The Lancet Oncology
, vol.13
, pp. 509-517
-
-
van den Eertwegh, A.J.M.1
Versluis, J.2
van den Berg, H.P.3
Santegoets, S.J.A.M.4
van Moorselaar, R.J.A.5
van der Sluis, T.M.6
Gall, H.E.7
Harding, T.C.8
Jooss, K.9
Lowy, I.10
-
204
-
-
67649484348
-
Skin-specific promoters for genetic immunisation by DNA electroporation
-
Vandermeulen, G., Richiardi, H., Escriou, V., Ni, J., Fournier, P., Schirrmacher, V.,.. Préat, V., Skin-specific promoters for genetic immunisation by DNA electroporation. Vaccine 27 (2009), 4272–4277.
-
(2009)
Vaccine
, vol.27
, pp. 4272-4277
-
-
Vandermeulen, G.1
Richiardi, H.2
Escriou, V.3
Ni, J.4
Fournier, P.5
Schirrmacher, V.6
Préat, V.7
-
205
-
-
2942679083
-
The immunobiology of the TLR9 subfamily
-
Wagner, H., The immunobiology of the TLR9 subfamily. Trends in Immunology 25 (2004), 381–386.
-
(2004)
Trends in Immunology
, vol.25
, pp. 381-386
-
-
Wagner, H.1
-
206
-
-
84893498955
-
In vivo electroporation of minicircle DNA as a novel method of vaccine delivery to enhance HIV-1-specific immune responses
-
Wang, Q., Jiang, W., Chen, Y., Liu, P., Sheng, C., Chen, S.,.. Huang, W., In vivo electroporation of minicircle DNA as a novel method of vaccine delivery to enhance HIV-1-specific immune responses. Journal of Virology 88 (2013), 1924–1934.
-
(2013)
Journal of Virology
, vol.88
, pp. 1924-1934
-
-
Wang, Q.1
Jiang, W.2
Chen, Y.3
Liu, P.4
Sheng, C.5
Chen, S.6
Huang, W.7
-
207
-
-
37049027488
-
GVAX: An allogeneic, whole-cell, GM-CSF-secreting cellular immunotherapy for the treatment of prostate cancer
-
Ward, J.E., McNeel, D.G., GVAX: An allogeneic, whole-cell, GM-CSF-secreting cellular immunotherapy for the treatment of prostate cancer. Expert Opinion on Biological Therapy 7 (2007), 1893–1902.
-
(2007)
Expert Opinion on Biological Therapy
, vol.7
, pp. 1893-1902
-
-
Ward, J.E.1
McNeel, D.G.2
-
208
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial
-
Weber, J.S., D'Angelo, S.P., Minor, D., Hodi, F.S., Gutzmer, R., Neyns, B., Hoeller, C., Khushalani, N.I., Miller, W.H., Lao, C.D., et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): A randomised, controlled, open-label, phase 3 trial. The Lancet Oncology 16 (2015), 375–384.
-
(2015)
The Lancet Oncology
, vol.16
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
Hodi, F.S.4
Gutzmer, R.5
Neyns, B.6
Hoeller, C.7
Khushalani, N.I.8
Miller, W.H.9
Lao, C.D.10
-
209
-
-
84906047226
-
The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer
-
Weitzenfeld, P., Ben-Baruch, A., The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer. Cancer Letters 352 (2014), 36–53.
-
(2014)
Cancer Letters
, vol.352
, pp. 36-53
-
-
Weitzenfeld, P.1
Ben-Baruch, A.2
-
210
-
-
84860528921
-
A systematic analysis of experimental immunotherapies on tumors differing in size and duration of growth
-
Wen, F.T., Thisted, R.A., Rowley, D.A., Schreiber, H., A systematic analysis of experimental immunotherapies on tumors differing in size and duration of growth. OncoImmunology 1 (2012), 172–178.
-
(2012)
OncoImmunology
, vol.1
, pp. 172-178
-
-
Wen, F.T.1
Thisted, R.A.2
Rowley, D.A.3
Schreiber, H.4
-
211
-
-
84906914880
-
Vector design for improved DNA vaccine efficacy, safety and production
-
Williams, J.A., Vector design for improved DNA vaccine efficacy, safety and production. Vaccine 1 (2013), 225–249.
-
(2013)
Vaccine
, vol.1
, pp. 225-249
-
-
Williams, J.A.1
-
212
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff, J.A., Malone, R.W., Williams, P., Chong, W., Acsadi, G., Jani, A., Felgner, P.L., Direct gene transfer into mouse muscle in vivo. Science 247 (1990), 1465–1468.
-
(1990)
Science
, vol.247
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
Felgner, P.L.7
-
213
-
-
84873724533
-
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA
-
Wu, J., Sun, L., Chen, X., Du, F., Shi, H., Chen, C., Chen, Z.J., Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA. Science 339 (2012), 826–830.
-
(2012)
Science
, vol.339
, pp. 826-830
-
-
Wu, J.1
Sun, L.2
Chen, X.3
Du, F.4
Shi, H.5
Chen, C.6
Chen, Z.J.7
-
214
-
-
0028244596
-
Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus
-
Xiang, Z.Q., Spitalnik, S., Tran, M., Wunner, W.H., Cheng, J., Ertl, H.C., Vaccination with a plasmid vector carrying the rabies virus glycoprotein gene induces protective immunity against rabies virus. Virology 199 (1994), 132–140.
-
(1994)
Virology
, vol.199
, pp. 132-140
-
-
Xiang, Z.Q.1
Spitalnik, S.2
Tran, M.3
Wunner, W.H.4
Cheng, J.5
Ertl, H.C.6
-
215
-
-
34548067921
-
Bacterial magnetic particles (BMPs)-PEI as a novel and efficient non-viral gene delivery system
-
Xiang, L., Bin, W., Huali, J., Wei, J., Jiesheng, T., Feng, G., Ying, L., Bacterial magnetic particles (BMPs)-PEI as a novel and efficient non-viral gene delivery system. The Journal of Gene Medicine 9 (2007), 679–690.
-
(2007)
The Journal of Gene Medicine
, vol.9
, pp. 679-690
-
-
Xiang, L.1
Bin, W.2
Huali, J.3
Wei, J.4
Jiesheng, T.5
Feng, G.6
Ying, L.7
-
216
-
-
28844459086
-
Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant
-
Yamano, T., Kaneda, Y., Huang, S., Hiramatsu, S.H., Hoon, D.S.B., Enhancement of immunity by a DNA melanoma vaccine against TRP2 with CCL21 as an adjuvant. Molecular Therapy: The Journal of the American Society of Gene Therapy 13 (2006), 194–202.
-
(2006)
Molecular Therapy: The Journal of the American Society of Gene Therapy
, vol.13
, pp. 194-202
-
-
Yamano, T.1
Kaneda, Y.2
Huang, S.3
Hiramatsu, S.H.4
Hoon, D.S.B.5
-
217
-
-
34247118770
-
Immunity against breast cancer by TERT DNA vaccine primed with chemokine CCL21
-
Yamano, T., Kaneda, Y., Hiramatsu, S.H., Huang, S., Tran, A.N., Giuliano, A.E., Hoon, D.S.B., Immunity against breast cancer by TERT DNA vaccine primed with chemokine CCL21. Cancer Gene Therapy 14 (2007), 451–459.
-
(2007)
Cancer Gene Therapy
, vol.14
, pp. 451-459
-
-
Yamano, T.1
Kaneda, Y.2
Hiramatsu, S.H.3
Huang, S.4
Tran, A.N.5
Giuliano, A.E.6
Hoon, D.S.B.7
-
218
-
-
84860390598
-
Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers
-
Yan, M., Jene, N., Byrne, D., Millar, E.K.A., O'Toole, S.A., McNeil, C.M., Bates, G.J., Harris, A.L., Banham, A.H., Sutherland, R.L., et al. Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers. Breast Cancer Research, 13, 2011, R47.
-
(2011)
Breast Cancer Research
, vol.13
, pp. R47
-
-
Yan, M.1
Jene, N.2
Byrne, D.3
Millar, E.K.A.4
O'Toole, S.A.5
McNeil, C.M.6
Bates, G.J.7
Harris, A.L.8
Banham, A.H.9
Sutherland, R.L.10
-
219
-
-
84925942984
-
Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model
-
Yan, J., Tingey, C., Lyde, R., Gorham, T.C., Choo, D.K., Muthumani, A., Myles, D., Weiner, L.P., Kraynyak, K.A., Reuschel, E.L., et al. Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model. Cancer Gene Therapy 21 (2014), 507–517.
-
(2014)
Cancer Gene Therapy
, vol.21
, pp. 507-517
-
-
Yan, J.1
Tingey, C.2
Lyde, R.3
Gorham, T.C.4
Choo, D.K.5
Muthumani, A.6
Myles, D.7
Weiner, L.P.8
Kraynyak, K.A.9
Reuschel, E.L.10
-
220
-
-
84920972734
-
Targeting DNA vaccines to myeloid cells using a small peptide
-
Ye, C., Choi, J.G., Abraham, S., Shankar, P., Manjunath, N., Targeting DNA vaccines to myeloid cells using a small peptide. European Journal of Immunology 45 (2014), 82–88.
-
(2014)
European Journal of Immunology
, vol.45
, pp. 82-88
-
-
Ye, C.1
Choi, J.G.2
Abraham, S.3
Shankar, P.4
Manjunath, N.5
-
221
-
-
84946031852
-
Antigen spreading-induced CD8 + T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells
-
Yu, Z., Tan, Z., Lee, B.K., Tang, J., Wu, X., Cheung, K.-W.,.. Chen, Z., Antigen spreading-induced CD8 + T cells confer protection against the lethal challenge of wild-type malignant mesothelioma by eliminating myeloid-derived suppressor cells. Oncotarget 6 (2015), 32426–32438.
-
(2015)
Oncotarget
, vol.6
, pp. 32426-32438
-
-
Yu, Z.1
Tan, Z.2
Lee, B.K.3
Tang, J.4
Wu, X.5
Cheung, K.-W.6
Chen, Z.7
-
222
-
-
84940480052
-
Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling
-
Zhang, H., Tang, K., Zhang, Y., Ma, R., Ma, J., Li, Y., Luo, S., Liang, X., Ji, T., Gu, Z., et al. Cell-free tumor microparticle vaccines stimulate dendritic cells via cGAS/STING signaling. Cancer Immunology Research 3 (2014), 196–205.
-
(2014)
Cancer Immunology Research
, vol.3
, pp. 196-205
-
-
Zhang, H.1
Tang, K.2
Zhang, Y.3
Ma, R.4
Ma, J.5
Li, Y.6
Luo, S.7
Liang, X.8
Ji, T.9
Gu, Z.10
-
223
-
-
0031863853
-
Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes
-
Zitvogel, L., Regnault, A., Lozier, A., Wolfers, J., Flament, C., Tenza, D.,.. Amigorena, S., Eradication of established murine tumors using a novel cell-free vaccine: Dendritic cell-derived exosomes. Nature Medicine 4 (1998), 594–600.
-
(1998)
Nature Medicine
, vol.4
, pp. 594-600
-
-
Zitvogel, L.1
Regnault, A.2
Lozier, A.3
Wolfers, J.4
Flament, C.5
Tenza, D.6
Amigorena, S.7
|