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Volumn 14, Issue 2, 2012, Pages 128-137

CCL19 (ELC) improves TH1-polarized immune responses and protective immunity in a murine Her2/neu DNA vaccination model

Author keywords

CCL19; Chemokines; DNA vaccination; ELC; Her2 neu

Indexed keywords

CANCER VACCINE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; MACROPHAGE INFLAMMATORY PROTEIN 3BETA;

EID: 84857179775     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1651     Document Type: Article
Times cited : (18)

References (60)
  • 1
    • 0034046182 scopus 로고    scopus 로고
    • DNA vaccines: immunology, application and optimization
    • Gurunathan S, Klinman DM, Seder RA. DNA vaccines: immunology, application and optimization. Ann Rev Immunol 2000; 18: 927-974.
    • (2000) Ann Rev Immunol , vol.18 , pp. 927-974
    • Gurunathan, S.1    Klinman, D.M.2    Seder, R.A.3
  • 3
    • 85047691459 scopus 로고    scopus 로고
    • Developing DNA vaccines that call to dendritic cells
    • Kutzler MA, Weiner DB. Developing DNA vaccines that call to dendritic cells. J Clin Invest 2004; 114: 1241-1244.
    • (2004) J Clin Invest , vol.114 , pp. 1241-1244
    • Kutzler, M.A.1    Weiner, D.B.2
  • 4
    • 38549175830 scopus 로고    scopus 로고
    • DNA vaccines: precision tools for activating effective immunity against cancer
    • Rice J, Ottensmeier CH, Stevenson F. DNA vaccines: precision tools for activating effective immunity against cancer. Nat Rev Immunol 2008; 8: 108-120.
    • (2008) Nat Rev Immunol , vol.8 , pp. 108-120
    • Rice, J.1    Ottensmeier, C.H.2    Stevenson, F.3
  • 5
  • 6
    • 45549092607 scopus 로고    scopus 로고
    • Cancer immunology
    • Fin OJ. Cancer immunology. N Engl J Med 2008; 358: 2704-2715.
    • (2008) N Engl J Med , vol.358 , pp. 2704-2715
    • Fin, O.J.1
  • 7
    • 0035925610 scopus 로고    scopus 로고
    • Genetic adjuvants for DNA vaccines
    • Scheerlinck JP. Genetic adjuvants for DNA vaccines. Vaccine 2001; 19: 2647-2656.
    • (2001) Vaccine , vol.19 , pp. 2647-2656
    • Scheerlinck, J.P.1
  • 8
    • 34247255391 scopus 로고    scopus 로고
    • Chemical adjuvants for plasmid DNA vaccines
    • Greenland JR, Letvin NL. Chemical adjuvants for plasmid DNA vaccines. Vaccine 2007; 25: 3731-3741.
    • (2007) Vaccine , vol.25 , pp. 3731-3741
    • Greenland, J.R.1    Letvin, N.L.2
  • 9
    • 34247196171 scopus 로고    scopus 로고
    • Clinical utilisation of chemokines to combat cancer: the double-edged sword
    • DellÁgnola C, Biragyn A. Clinical utilisation of chemokines to combat cancer: the double-edged sword. Exp Rev Vaccines 2007; 6: 267-283.
    • (2007) Exp Rev Vaccines , vol.6 , pp. 267-283
    • Dellágnola, C.1    Biragyn, A.2
  • 10
    • 2342514244 scopus 로고    scopus 로고
    • Cancer immunotherapy with chemoattractant peptides
    • Coscia M, Biragyn A. Cancer immunotherapy with chemoattractant peptides. Sem Cancer Biol 2004; 14: 209-218.
    • (2004) Sem Cancer Biol , vol.14 , pp. 209-218
    • Coscia, M.1    Biragyn, A.2
  • 11
    • 84857143675 scopus 로고    scopus 로고
    • Chemokine receptor expression in effector and memory T cell subsets
    • Badolato R, Sozzani S (eds) Birkhäuser Verlag: Basel
    • Messi M, Sallusto F. Chemokine receptor expression in effector and memory T cell subsets. In Lymphocyte Tafficking in health and Disease, Badolato R, Sozzani S (eds) Birkhäuser Verlag: Basel, 2006; 55-70.
    • (2006) Lymphocyte Tafficking in health and Disease , pp. 55-70
    • Messi, M.1    Sallusto, F.2
  • 12
    • 27144525192 scopus 로고    scopus 로고
    • Dendritic cell trafficking: more than just chemokines
    • Sozzani S. Dendritic cell trafficking: more than just chemokines. Cytokine Growth Factor Rev 2005; 16: 581-592.
    • (2005) Cytokine Growth Factor Rev , vol.16 , pp. 581-592
    • Sozzani, S.1
  • 13
    • 33747050163 scopus 로고    scopus 로고
    • T cells and their partners: the chemokine dating agency
    • Viola A, Contento RL, Molon B. T cells and their partners: the chemokine dating agency. Trends Immunol 2006; 27: 421-427.
    • (2006) Trends Immunol , vol.27 , pp. 421-427
    • Viola, A.1    Contento, R.L.2    Molon, B.3
  • 14
    • 50049105173 scopus 로고    scopus 로고
    • Orchestrating the orchestrators: chemokines in control of T cell traffic
    • Bromley SK, Mempel TR, Luster AD. Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat Immunol 2008; 9: 970-980.
    • (2008) Nat Immunol , vol.9 , pp. 970-980
    • Bromley, S.K.1    Mempel, T.R.2    Luster, A.D.3
  • 15
    • 42649086026 scopus 로고    scopus 로고
    • CCR7 and its ligands: balancing immunity and tolerance
    • Förster R, Davalos-Misslitz AC, Rot A. CCR7 and its ligands: balancing immunity and tolerance. Nat Rev Immunol 2008; 8: 362-371.
    • (2008) Nat Rev Immunol , vol.8 , pp. 362-371
    • Förster, R.1    Davalos-Misslitz, A.C.2    Rot, A.3
  • 16
    • 14144250814 scopus 로고    scopus 로고
    • Increased expression of CCL18, CCL19 and CCL17 by dendritic cells from patients with rheumatoid arthritis, and regulation by Fc gamma receptors
    • Radstake TR, van der Voort M, ten Brummelhuis M, et al. Increased expression of CCL18, CCL19 and CCL17 by dendritic cells from patients with rheumatoid arthritis, and regulation by Fc gamma receptors. Ann Rheum Dis 2005; 64: 359-367.
    • (2005) Ann Rheum Dis , vol.64 , pp. 359-367
    • Radstake, T.R.1    van der Voort, M.2    ten Brummelhuis, M.3
  • 17
    • 33748866330 scopus 로고    scopus 로고
    • Surface-bound chemokines capture and prime T cells for synapse formation
    • Friedman RS, Jacobell J, Krummel MF. Surface-bound chemokines capture and prime T cells for synapse formation. Nat Immunol 2006; 7: 1101-1108.
    • (2006) Nat Immunol , vol.7 , pp. 1101-1108
    • Friedman, R.S.1    Jacobell, J.2    Krummel, M.F.3
  • 18
  • 19
    • 0242624620 scopus 로고    scopus 로고
    • Biologic and therapeutic role of HER2 in cancer
    • Menard S, Pupa SM, Campiglio M, Tagliabue E. Biologic and therapeutic role of HER2 in cancer. Oncogene 2003; 22: 6570-6578.
    • (2003) Oncogene , vol.22 , pp. 6570-6578
    • Menard, S.1    Pupa, S.M.2    Campiglio, M.3    Tagliabue, E.4
  • 20
    • 34249094199 scopus 로고    scopus 로고
    • CCL19 (ELC) as an adjuvant for DNA vaccination: Induction of a TH1-type T cell response and enhancement of antitumor immunity
    • Westermann J, Nguyen-Hoai T, Baldenhofer G, et al. CCL19 (ELC) as an adjuvant for DNA vaccination: Induction of a TH1-type T cell response and enhancement of antitumor immunity. Cancer Gene Ther 2007; 14: 523-532.
    • (2007) Cancer Gene Ther , vol.14 , pp. 523-532
    • Westermann, J.1    Nguyen-Hoai, T.2    Baldenhofer, G.3
  • 21
    • 0036644712 scopus 로고    scopus 로고
    • Differing activities of homeostatic chemokine CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis
    • Luther SA, Bidgol A, Hargreaves DC, et al. Differing activities of homeostatic chemokine CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol 2002; 169: 424-433.
    • (2002) J Immunol , vol.169 , pp. 424-433
    • Luther, S.A.1    Bidgol, A.2    Hargreaves, D.C.3
  • 22
    • 0031204947 scopus 로고    scopus 로고
    • Peptides derived from a wild-type murine proto-oncogenec-erbB-2/HER2/neu can induce CTL and tumor suppression in syngeneic hosts
    • Nagata Y, Furugen R, Hiasa A, et al. Peptides derived from a wild-type murine proto-oncogenec-erbB-2/HER2/neu can induce CTL and tumor suppression in syngeneic hosts. J Immunol 1997; 159: 1336-1343.
    • (1997) J Immunol , vol.159 , pp. 1336-1343
    • Nagata, Y.1    Furugen, R.2    Hiasa, A.3
  • 23
    • 0036132653 scopus 로고    scopus 로고
    • Quantitative measurement of anti-ErbB-2 antibody by flow cytometry and ELISA
    • Piechoski MP, Pilon SA, Wei WZ. Quantitative measurement of anti-ErbB-2 antibody by flow cytometry and ELISA. J Immunol Methods 2002; 259: 33-42.
    • (2002) J Immunol Methods , vol.259 , pp. 33-42
    • Piechoski, M.P.1    Pilon, S.A.2    Wei, W.Z.3
  • 24
    • 0036391523 scopus 로고    scopus 로고
    • Cellular immunity to the Her-2/neu protooncogene
    • Kiessling R, Wei WZ, Herrmann F, et al. Cellular immunity to the Her-2/neu protooncogene. Adv Cancer Res 2002; 85: 101-144.
    • (2002) Adv Cancer Res , vol.85 , pp. 101-144
    • Kiessling, R.1    Wei, W.Z.2    Herrmann, F.3
  • 26
    • 33646170120 scopus 로고    scopus 로고
    • A breast cancer vaccines: a clinical reality or fairy tale?
    • Curigliano G, Spitaleri G, Pietri E, et al. A breast cancer vaccines: a clinical reality or fairy tale? Ann Oncol 2006; 17: 750-762.
    • (2006) Ann Oncol , vol.17 , pp. 750-762
    • Curigliano, G.1    Spitaleri, G.2    Pietri, E.3
  • 29
    • 0032952692 scopus 로고    scopus 로고
    • Protection against mammary tumor growth by vaccination with full-length, modified human ErbB-2 DNA
    • Wei WZ, Shi WP, Galy A, et al. Protection against mammary tumor growth by vaccination with full-length, modified human ErbB-2 DNA. Int J Cancer 1999; 81: 748-754.
    • (1999) Int J Cancer , vol.81 , pp. 748-754
    • Wei, W.Z.1    Shi, W.P.2    Galy, A.3
  • 30
    • 0036720398 scopus 로고    scopus 로고
    • The roles of FLT3 in hematopoiesis and leukemia
    • Gilliland DG, Griffin JD. The roles of FLT3 in hematopoiesis and leukemia. Blood 2002; 100: 1532-1542.
    • (2002) Blood , vol.100 , pp. 1532-1542
    • Gilliland, D.G.1    Griffin, J.D.2
  • 31
    • 3242786493 scopus 로고    scopus 로고
    • Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization
    • Westermann J, Nguyen-Hoai T, Mollweide A, et al. Flt-3 ligand as adjuvant for DNA vaccination augments immune responses but does not skew TH1/TH2 polarization. Gene Ther 2004; 11: 1048-1056.
    • (2004) Gene Ther , vol.11 , pp. 1048-1056
    • Westermann, J.1    Nguyen-Hoai, T.2    Mollweide, A.3
  • 32
    • 1242296929 scopus 로고    scopus 로고
    • CD4+ T cell-mediated Her-2/neu-specific tumor rejection in the absence of B cells
    • Linndencrona JA, Preise S, Kammertöns T, et al. CD4+ T cell-mediated Her-2/neu-specific tumor rejection in the absence of B cells. Int J Cancer 2004; 109: 259-264.
    • (2004) Int J Cancer , vol.109 , pp. 259-264
    • Linndencrona, J.A.1    Preise, S.2    Kammertöns, T.3
  • 33
    • 68049111686 scopus 로고    scopus 로고
    • Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice
    • Wei H, Wang S, Zhang D, et al. Targeted delivery of tumor antigens to activated dendritic cells via CD11c molecules induces potent antitumor immunity in mice. Clin Cancer Res 2009; 15: 4612-4621.
    • (2009) Clin Cancer Res , vol.15 , pp. 4612-4621
    • Wei, H.1    Wang, S.2    Zhang, D.3
  • 34
    • 0028908324 scopus 로고
    • Paracrine cytokine adjuvants in cancer immunotherapy
    • Pardoll DM. Paracrine cytokine adjuvants in cancer immunotherapy. Annu Rev Immunol 1995; 13: 399-415.
    • (1995) Annu Rev Immunol , vol.13 , pp. 399-415
    • Pardoll, D.M.1
  • 35
    • 0027538181 scopus 로고
    • Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity
    • Dranoff G, Jaffee E, Lazenby A, et al. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci USA 1993; 90: 3539-3543.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3539-3543
    • Dranoff, G.1    Jaffee, E.2    Lazenby, A.3
  • 36
    • 4043174820 scopus 로고    scopus 로고
    • Immunoprevention of mammary carcinoma in HER-2/neu transgenic mice is IFN-γ and B cell dependent
    • Nanni P, Landuzzi L, Nicoletti G, et al. Immunoprevention of mammary carcinoma in HER-2/neu transgenic mice is IFN-γ and B cell dependent. J Immunol 2004; 173: 2288-2296.
    • (2004) J Immunol , vol.173 , pp. 2288-2296
    • Nanni, P.1    Landuzzi, L.2    Nicoletti, G.3
  • 37
    • 0035116901 scopus 로고    scopus 로고
    • The collaboration of both humoral and cellular HER-2/neu-targeted immune responses is required for the complete eradication of HER-2/neu-expressing tumors
    • Reilly RT, Machiels J-PH, Emens LA, et al. The collaboration of both humoral and cellular HER-2/neu-targeted immune responses is required for the complete eradication of HER-2/neu-expressing tumors. Cancer Res 2001; 61: 880-883.
    • (2001) Cancer Res , vol.61 , pp. 880-883
    • Reilly, R.T.1    Machiels, J.-P.2    Emens, L.A.3
  • 39
    • 0034668011 scopus 로고    scopus 로고
    • + T cells in the priming and effector/memory phases of adoptive immunotherapy
    • + T cells in the priming and effector/memory phases of adoptive immunotherapy. J Immunol 2000; 165: 4246-4253.
    • (2000) J Immunol , vol.165 , pp. 4246-4253
    • Hu, H.M.1    Winter, H.2    Urba, W.J.3    Fox, B.A.4
  • 41
    • 66249086885 scopus 로고    scopus 로고
    • Memory and cellular immunity induced by a DNA vaccine encoding self antigen TPD52 administered with soluble GM-CSF
    • Lewis JD, Sullivan LA, Byrne JA, de Riese W, Bright RK. Memory and cellular immunity induced by a DNA vaccine encoding self antigen TPD52 administered with soluble GM-CSF. Cancer Immunol Immunother 2009; 58: 1337-49.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1337-1349
    • Lewis, J.D.1    Sullivan, L.A.2    Byrne, J.A.3    de Riese, W.4    Bright, R.K.5
  • 42
    • 0035860604 scopus 로고    scopus 로고
    • Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCR7 ligands
    • Eo SK, Lee S, Kumaraguru U, Rouse BT. Immunopotentiation of DNA vaccine against herpes simplex virus via co-delivery of plasmid DNA expressing CCR7 ligands. Vaccine 2001; 19: 4685-4693.
    • (2001) Vaccine , vol.19 , pp. 4685-4693
    • Eo, S.K.1    Lee, S.2    Kumaraguru, U.3    Rouse, B.T.4
  • 43
    • 0242409175 scopus 로고    scopus 로고
    • Codelivery of CCR7 ligands as molecular adjuvants enhances the protective immune response against herpes simplex virus type 1
    • Toka FN, Gierynska M, Rouse BT. Codelivery of CCR7 ligands as molecular adjuvants enhances the protective immune response against herpes simplex virus type 1. J Virol 2003; 77: 12742-12752.
    • (2003) J Virol , vol.77 , pp. 12742-12752
    • Toka, F.N.1    Gierynska, M.2    Rouse, B.T.3
  • 44
    • 12144291472 scopus 로고    scopus 로고
    • Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy
    • Okada N, Gao J-Q, Sasaki A, et al. Anti-tumor activity of chemokine is affected by both kinds of tumors and the activation state of the host's immune system: implications for chemokine-based cancer immunotherapy. Biochem Biophys Res Commun 2004; 317: 68-76.
    • (2004) Biochem Biophys Res Commun , vol.317 , pp. 68-76
    • Okada, N.1    Gao, J.-Q.2    Sasaki, A.3
  • 45
    • 10744232509 scopus 로고    scopus 로고
    • EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-γ-dependent antitumor responses in a lung cancer model
    • Hillinger S, Yang SC, Zhu L, et al. EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-γ-dependent antitumor responses in a lung cancer model. J Immunol 2003; 171: 6457-6465.
    • (2003) J Immunol , vol.171 , pp. 6457-6465
    • Hillinger, S.1    Yang, S.C.2    Zhu, L.3
  • 46
    • 33645736489 scopus 로고    scopus 로고
    • CCL19 reduces tumour burden in a model of advanced lung cancer
    • Hillinger S, Yang SC, Batra RK, et al. CCL19 reduces tumour burden in a model of advanced lung cancer. Br J Cancer 2006; 94: 1029-1034.
    • (2006) Br J Cancer , vol.94 , pp. 1029-1034
    • Hillinger, S.1    Yang, S.C.2    Batra, R.K.3
  • 47
    • 0033658153 scopus 로고    scopus 로고
    • Understanding dendritic cell and T-Lymphocyte traffic through the analysis of chemokine receptor expression
    • Sallusto F, Lanzavecchia A. Understanding dendritic cell and T-Lymphocyte traffic through the analysis of chemokine receptor expression. Immunol Rev 2000; 177: 134-140.
    • (2000) Immunol Rev , vol.177 , pp. 134-140
    • Sallusto, F.1    Lanzavecchia, A.2
  • 48
    • 0034655163 scopus 로고    scopus 로고
    • The CC chemokine CKb-11/MIP-3b/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells
    • Braun SE, Chen K, Foster RG, et al. The CC chemokine CKb-11/MIP-3b/ELC/Exodus 3 mediates tumor rejection of murine breast cancer cells through NK cells. J Immunol 2000; 164: 4025-4031.
    • (2000) J Immunol , vol.164 , pp. 4025-4031
    • Braun, S.E.1    Chen, K.2    Foster, R.G.3
  • 49
    • 79251559088 scopus 로고    scopus 로고
    • CCR7 is involved in the migration of neutrophils to lymph nodes
    • Beauvillain C, Cunin P, Doni A, et al. CCR7 is involved in the migration of neutrophils to lymph nodes. Blood 2010; 117: 1196-1204.
    • (2010) Blood , vol.117 , pp. 1196-1204
    • Beauvillain, C.1    Cunin, P.2    Doni, A.3
  • 50
    • 0035821218 scopus 로고    scopus 로고
    • The CCR7 ligand ELC (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment
    • Baekkevold ES, Yamanaka T, Palframan RT, et al. The CCR7 ligand ELC (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment. J Exp Med 2001; 193: 1105-1112.
    • (2001) J Exp Med , vol.193 , pp. 1105-1112
    • Baekkevold, E.S.1    Yamanaka, T.2    Palframan, R.T.3
  • 51
    • 0032490628 scopus 로고    scopus 로고
    • Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells
    • Ngo VN, Tang HL, Cyster JG. Epstein-Barr virus-induced molecule 1 ligand chemokine is expressed by dendritic cells in lymphoid tissues and strongly attracts naive T cells and activated B cells. J Exp Med 1998; 188: 181-191.
    • (1998) J Exp Med , vol.188 , pp. 181-191
    • Ngo, V.N.1    Tang, H.L.2    Cyster, J.G.3
  • 52
    • 0032531094 scopus 로고    scopus 로고
    • EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation
    • Yanagihara S, Komura E, Nagafune J, Watarai H, Yamaguchi Y. EBI1/CCR7 is a new member of dendritic cell chemokine receptor that is up-regulated upon maturation. J Immunol 1998; 161: 3092-3102.
    • (1998) J Immunol , vol.161 , pp. 3092-3102
    • Yanagihara, S.1    Komura, E.2    Nagafune, J.3    Watarai, H.4    Yamaguchi, Y.5
  • 53
    • 29144451837 scopus 로고    scopus 로고
    • Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation
    • Lerbe MC, Burwell T, Vieira PL, et al. Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation. Immunol Cell Biol 2005; 83: 525-535.
    • (2005) Immunol Cell Biol , vol.83 , pp. 525-535
    • Lerbe, M.C.1    Burwell, T.2    Vieira, P.L.3
  • 54
    • 0037105462 scopus 로고    scopus 로고
    • CCL19 induces rapid dendritic extension of murine dendritic cells
    • Yanagawa Y, Onoé K. CCL19 induces rapid dendritic extension of murine dendritic cells. Blood 2002; 100: 1948-56.
    • (2002) Blood , vol.100 , pp. 1948-1956
    • Yanagawa, Y.1    Onoé, K.2
  • 55
    • 0037707281 scopus 로고    scopus 로고
    • CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities
    • Yanagawa Y, Onoé K. CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. Blood 2003; 101: 4923-4929.
    • (2003) Blood , vol.101 , pp. 4923-4929
    • Yanagawa, Y.1    Onoé, K.2
  • 56
    • 1842562212 scopus 로고    scopus 로고
    • Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance
    • Mapara MY, Sykes M. Tolerance and cancer: mechanisms of tumor evasion and strategies for breaking tolerance. J Clin Oncol 2004; 22: 1136-1151.
    • (2004) J Clin Oncol , vol.22 , pp. 1136-1151
    • Mapara, M.Y.1    Sykes, M.2
  • 57
    • 1642316449 scopus 로고    scopus 로고
    • + T cell repertoire against Her2/neu antigens in neu transgenic mice is of low avidity with anti tumor activity
    • + T cell repertoire against Her2/neu antigens in neu transgenic mice is of low avidity with anti tumor activity. Eur J Immunol 2004; 34: 752-761.
    • (2004) Eur J Immunol , vol.34 , pp. 752-761
    • Lustgarten, J.1    Dominguez, A.L.2    Cuadros, C.3
  • 58
    • 0036480589 scopus 로고    scopus 로고
    • The cellular and molecular mechanism of CD4/CD8 lineage commitment
    • Yasutomo K. The cellular and molecular mechanism of CD4/CD8 lineage commitment. J Med Invest 2002; 49: 1-6.
    • (2002) J Med Invest , vol.49 , pp. 1-6
    • Yasutomo, K.1
  • 59
    • 33751579927 scopus 로고    scopus 로고
    • Distinct and non-overlapping T cell receptor repertoires expanded by DNA vaccination in wild-type and her2/neu transgenic BALB/c mice
    • Rolla S, Nicolo C, Malinarich S, et al. Distinct and non-overlapping T cell receptor repertoires expanded by DNA vaccination in wild-type and her2/neu transgenic BALB/c mice. J Immunol 2006; 177: 7626-7633.
    • (2006) J Immunol , vol.177 , pp. 7626-7633
    • Rolla, S.1    Nicolo, C.2    Malinarich, S.3
  • 60
    • 21144454780 scopus 로고    scopus 로고
    • Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response
    • Ercolini AM, Ladle BH, Manning EA, et al. Recruitment of latent pools of high-avidity CD8(+) T cells to the antitumor immune response. J Exp Med 2005; 201: 1591-1602.
    • (2005) J Exp Med , vol.201 , pp. 1591-1602
    • Ercolini, A.M.1    Ladle, B.H.2    Manning, E.A.3


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