-
2
-
-
77953141534
-
Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign
-
Poschke I, Mougiakakos D, Hansson J, et al. Immature immunosuppressive CD14+HLA-DR-/low cells in melanoma patients are Stat3hi and overexpress CD80, CD83, and DC-sign. Cancer Res 2010; 70: 4335-45.
-
(2010)
Cancer Res
, vol.70
, pp. 4335-4345
-
-
Poschke, I.1
Mougiakakos, D.2
Hansson, J.3
-
3
-
-
77956990082
-
Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients
-
Nuber N, Curioni-Fontecedro A, Matter C, et al. Fine analysis of spontaneous MAGE-C1/CT7-specific immunity in melanoma patients. Proc Natl Acad Sci USA 2010; 107: 15187-92.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15187-15192
-
-
Nuber, N.1
Curioni-Fontecedro, A.2
Matter, C.3
-
4
-
-
34447258415
-
Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine
-
Filipazzi P, Valenti R, Huber V, et al. Identification of a new subset of myeloid suppressor cells in peripheral blood of melanoma patients with modulation by a granulocyte-macrophage colony-stimulation factor-based antitumor vaccine. J Clin Oncol 2007; 25: 2546-53.
-
(2007)
J Clin Oncol
, vol.25
, pp. 2546-2553
-
-
Filipazzi, P.1
Valenti, R.2
Huber, V.3
-
5
-
-
84856760496
-
Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation
-
Umansky V, Sevko A,. Overcoming immunosuppression in the melanoma microenvironment induced by chronic inflammation. Cancer Immunol Immunother 2012; 61: 275-82.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 275-282
-
-
Umansky, V.1
Sevko, A.2
-
7
-
-
77951086882
-
5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity
-
Vincent J, Mignot G, Chalmin F, et al. 5-Fluorouracil selectively kills tumor-associated myeloid-derived suppressor cells resulting in enhanced T cell-dependent antitumor immunity. Cancer Res 2010; 70: 3052-61.
-
(2010)
Cancer Res
, vol.70
, pp. 3052-3061
-
-
Vincent, J.1
Mignot, G.2
Chalmin, F.3
-
8
-
-
78649674576
-
Targeting immune suppressing myeloid-derived suppressor cells in oncology
-
Kao J, Ko EC, Eisenstein S, et al. Targeting immune suppressing myeloid-derived suppressor cells in oncology. Crit Rev Oncol Hematol 2011; 77: 12-9.
-
(2011)
Crit Rev Oncol Hematol
, vol.77
, pp. 12-19
-
-
Kao, J.1
Ko, E.C.2
Eisenstein, S.3
-
9
-
-
63549105681
-
Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients
-
Ko JS, Zea AH, Rini BI, et al. Sunitinib mediates reversal of myeloid-derived suppressor cell accumulation in renal cell carcinoma patients. Clin Cancer Res 2009; 15: 2148-57.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2148-2157
-
-
Ko, J.S.1
Zea, A.H.2
Rini, B.I.3
-
10
-
-
84862143053
-
Melanoma-induced immunosuppression and its neutralization
-
Umansky V, Sevko A,. Melanoma-induced immunosuppression and its neutralization. Semin Cancer Biol 2012; 22: 319-26.
-
(2012)
Semin Cancer Biol
, vol.22
, pp. 319-326
-
-
Umansky, V.1
Sevko, A.2
-
11
-
-
65249138393
-
Myeloid-derived suppressor cells: Linking inflammation and cancer
-
Ostrand-Rosenberg S, Sinha P,. Myeloid-derived suppressor cells: linking inflammation and cancer. J Immunol 2009; 182: 4499-506.
-
(2009)
J Immunol
, vol.182
, pp. 4499-4506
-
-
Ostrand-Rosenberg, S.1
Sinha, P.2
-
12
-
-
80053200887
-
Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer
-
Eruslanov E, Neuberger M, Daurkin I, et al. Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer 2012; 130: 1109-19.
-
(2012)
Int J Cancer
, vol.130
, pp. 1109-1119
-
-
Eruslanov, E.1
Neuberger, M.2
Daurkin, I.3
-
13
-
-
33749425534
-
Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells
-
Gallina G, Dolcetti L, Serafini P, et al. Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells. J Clin Invest 2006; 116: 2777-90.
-
(2006)
J Clin Invest
, vol.116
, pp. 2777-2790
-
-
Gallina, G.1
Dolcetti, L.2
Serafini, P.3
-
14
-
-
54849440346
-
Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy
-
Diaz-Montero CM, Salem ML, Nishimura MI, et al. Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin-cyclophosphamide chemotherapy. Cancer Immunol Immunother 2009; 58: 49-59.
-
(2009)
Cancer Immunol Immunother
, vol.58
, pp. 49-59
-
-
Diaz-Montero, C.M.1
Salem, M.L.2
Nishimura, M.I.3
-
15
-
-
79951823584
-
Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties
-
Brandau S, Trellakis S, Bruderek K, et al. Myeloid-derived suppressor cells in the peripheral blood of cancer patients contain a subset of immature neutrophils with impaired migratory properties. J Leuk Biol 2011; 89: 311-7.
-
(2011)
J Leuk Biol
, vol.89
, pp. 311-317
-
-
Brandau, S.1
Trellakis, S.2
Bruderek, K.3
-
16
-
-
60549088732
-
Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes
-
Rodriguez PC, Ernstoff MS, Hernandez C, et al. Arginase I-producing myeloid-derived suppressor cells in renal cell carcinoma are a subpopulation of activated granulocytes. Cancer Res 2009; 69: 1553-60.
-
(2009)
Cancer Res
, vol.69
, pp. 1553-1560
-
-
Rodriguez, P.C.1
Ernstoff, M.S.2
Hernandez, C.3
-
17
-
-
79952281184
-
Angiogenesis and immunity: A bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy
-
Tartour E, Pere H, Maillere B, et al. Angiogenesis and immunity: a bidirectional link potentially relevant for the monitoring of antiangiogenic therapy and the development of novel therapeutic combination with immunotherapy. Cancer Metastasis Rev 2011; 30: 83-95.
-
(2011)
Cancer Metastasis Rev
, vol.30
, pp. 83-95
-
-
Tartour, E.1
Pere, H.2
Maillere, B.3
-
18
-
-
53049088033
-
Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines
-
Smith FO, Downey SG, Klapper JA, et al. Treatment of metastatic melanoma using interleukin-2 alone or in conjunction with vaccines. Clin Cancer Res 2008; 14: 5610-8.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5610-5618
-
-
Smith, F.O.1
Downey, S.G.2
Klapper, J.A.3
-
19
-
-
84866910216
-
Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma
-
Gros A, Turcotte S, Wunderlich JR, et al. Myeloid cells obtained from the blood but not from the tumor can suppress T-cell proliferation in patients with melanoma. Clin Cancer Res 2012; 18: 5212-23.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5212-5223
-
-
Gros, A.1
Turcotte, S.2
Wunderlich, J.R.3
-
20
-
-
27844567142
-
Distinct sets of genetic alterations in melanoma
-
Curtin JA, Fridlyand J, Kageshita T, et al. Distinct sets of genetic alterations in melanoma. N Engl J Med 2005; 353: 2135-47.
-
(2005)
N Engl J Med
, vol.353
, pp. 2135-2147
-
-
Curtin, J.A.1
Fridlyand, J.2
Kageshita, T.3
-
21
-
-
84863393623
-
Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma
-
Wilmott JS, Long GV, Howle JR, et al. Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma. Clin Cancer Res 2012; 18: 1386-94.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1386-1394
-
-
Wilmott, J.S.1
Long, G.V.2
Howle, J.R.3
-
23
-
-
74949143594
-
Final version of 2009 AJCC melanoma staging and classification
-
Balch CM, Gershenwald JE, Soong SJ, et al. Final version of 2009 AJCC melanoma staging and classification. J Clin Oncol 2009; 27: 6199-206.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6199-6206
-
-
Balch, C.M.1
Gershenwald, J.E.2
Soong, S.J.3
-
24
-
-
84863463901
-
Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition
-
Zimmer L, Hillen U, Livingstone E, et al. Atypical melanocytic proliferations and new primary melanomas in patients with advanced melanoma undergoing selective BRAF inhibition. J Clin Oncol 2012; 30: 2375-83.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2375-2383
-
-
Zimmer, L.1
Hillen, U.2
Livingstone, E.3
-
25
-
-
0034594628
-
New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada
-
Therasse P, Arbuck SG, Eisenhauer EA, et al. New guidelines to evaluate the response to treatment in solid tumors. European Organization for Research and Treatment of Cancer, National Cancer Institute of the United States, National Cancer Institute of Canada. J Natl Cancer Inst 2000; 92: 205-16.
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 205-216
-
-
Therasse, P.1
Arbuck, S.G.2
Eisenhauer, E.A.3
-
26
-
-
37349120730
-
B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis
-
Ugurel S, Thirumaran RK, Bloethner S, et al. B-RAF and N-RAS mutations are preserved during short time in vitro propagation and differentially impact prognosis. PLoS One 2007; 2: e236.
-
(2007)
PLoS One
, vol.2
-
-
Ugurel, S.1
Thirumaran, R.K.2
Bloethner, S.3
-
27
-
-
46049098560
-
A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells
-
Hoechst B, Ormandy LA, Ballmaier M, et al. A new population of myeloid-derived suppressor cells in hepatocellular carcinoma patients induces CD4(+)CD25(+)Foxp3(+) T cells. Gastroenterology 2008; 135: 234-43.
-
(2008)
Gastroenterology
, vol.135
, pp. 234-243
-
-
Hoechst, B.1
Ormandy, L.A.2
Ballmaier, M.3
-
28
-
-
84857370520
-
IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model
-
Schilling B, Harasymczuk M, Schuler P, et al. IRX-2, a novel biologic, favors the expansion of T effector over T regulatory cells in a human tumor microenvironment model. J Mol Med (Berl) 2012; 90: 139-47.
-
(2012)
J Mol Med (Berl)
, vol.90
, pp. 139-147
-
-
Schilling, B.1
Harasymczuk, M.2
Schuler, P.3
-
29
-
-
84865715288
-
Neutrophils and granulocytic myeloid-derived suppressor cells: Immunophenotyping, cell biology and clinical relevance in human oncology
-
Dumitru CA, Moses K, Trellakis S, et al. Neutrophils and granulocytic myeloid-derived suppressor cells: immunophenotyping, cell biology and clinical relevance in human oncology. Cancer Immunol Immunother 2012; 61: 1155-67.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1155-1167
-
-
Dumitru, C.A.1
Moses, K.2
Trellakis, S.3
-
30
-
-
84866914804
-
The power of negative thinking: Which cells limit tumor immunity?
-
Tang S, Lotze MT,. The power of negative thinking: which cells limit tumor immunity? Clin Cancer Res 2012; 18: 5157-9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 5157-5159
-
-
Tang, S.1
Lotze, M.T.2
-
31
-
-
2542471742
-
Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients
-
Ugurel S, Uhlig D, Pfohler C, et al. Down-regulation of HLA class II and costimulatory CD86/B7-2 on circulating monocytes from melanoma patients. Cancer Immunol Immunother 2004; 53: 551-9.
-
(2004)
Cancer Immunol Immunother
, vol.53
, pp. 551-559
-
-
Ugurel, S.1
Uhlig, D.2
Pfohler, C.3
-
32
-
-
77949718839
-
Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer
-
Nagaraj S, Youn JI, Weber H, et al. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clin Cancer Res 2010; 16: 1812-23.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1812-1823
-
-
Nagaraj, S.1
Youn, J.I.2
Weber, H.3
-
33
-
-
84874117271
-
Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies
-
Duffy A, Zhao F, Haile L, et al. Comparative analysis of monocytic and granulocytic myeloid-derived suppressor cell subsets in patients with gastrointestinal malignancies. Cancer Immunol Immunother 2013; 62: 299-307.
-
(2013)
Cancer Immunol Immunother
, vol.62
, pp. 299-307
-
-
Duffy, A.1
Zhao, F.2
Haile, L.3
-
34
-
-
84866916560
-
Metabolism of l-arginine by myeloid-derived suppressor cells in cancer: Mechanisms of T cell suppression and therapeutic perspectives
-
Raber P, Ochoa AC, Rodriguez PC,. Metabolism of l-arginine by myeloid-derived suppressor cells in cancer: mechanisms of T cell suppression and therapeutic perspectives. Immunol Invest 2012; 41: 614-34.
-
(2012)
Immunol Invest
, vol.41
, pp. 614-634
-
-
Raber, P.1
Ochoa, A.C.2
Rodriguez, P.C.3
-
35
-
-
70350133511
-
IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients
-
Mandruzzato S, Solito S, Falisi E, et al. IL4Ralpha+ myeloid-derived suppressor cell expansion in cancer patients. J Immunol 2009; 182: 6562-8.
-
(2009)
J Immunol
, vol.182
, pp. 6562-6568
-
-
Mandruzzato, S.1
Solito, S.2
Falisi, E.3
-
36
-
-
84858202940
-
Aptamer-mediated blockade of IL4Ralpha triggers apoptosis of MDSCs and limits tumor progression
-
Roth F, De La Fuente AC, Vella JL, et al. Aptamer-mediated blockade of IL4Ralpha triggers apoptosis of MDSCs and limits tumor progression. Cancer Res 2012; 72: 1373-83.
-
(2012)
Cancer Res
, vol.72
, pp. 1373-1383
-
-
Roth, F.1
De La Fuente, A.C.2
Vella, J.L.3
-
37
-
-
84864744528
-
Tumor-induced myeloid-derived suppressor cell function is independent of IFN-gamma and IL-4Ralpha
-
Sinha P, Parker KH, Horn L, et al. Tumor-induced myeloid-derived suppressor cell function is independent of IFN-gamma and IL-4Ralpha. Eur J Immunol 2012; 42: 2052-9.
-
(2012)
Eur J Immunol
, vol.42
, pp. 2052-2059
-
-
Sinha, P.1
Parker, K.H.2
Horn, L.3
-
38
-
-
79958066494
-
Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines
-
Lechner MG, Megiel C, Russell SM, et al. Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines. J Transl Med 2011; 9: 90.
-
(2011)
J Transl Med
, vol.9
, pp. 90
-
-
Lechner, M.G.1
Megiel, C.2
Russell, S.M.3
-
39
-
-
77956920766
-
Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells
-
Lechner MG, Liebertz DJ, Epstein AL,. Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cells. J Immunol 2010; 185: 2273-84.
-
(2010)
J Immunol
, vol.185
, pp. 2273-2284
-
-
Lechner, M.G.1
Liebertz, D.J.2
Epstein, A.L.3
-
40
-
-
33745859743
-
The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells
-
Sumimoto H, Imabayashi F, Iwata T, et al. The BRAF-MAPK signaling pathway is essential for cancer-immune evasion in human melanoma cells. J Exp Med 2006; 203: 1651-6.
-
(2006)
J Exp Med
, vol.203
, pp. 1651-1656
-
-
Sumimoto, H.1
Imabayashi, F.2
Iwata, T.3
-
41
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF, et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-23.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
42
-
-
33644784733
-
IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients
-
Ahmadzadeh M, Rosenberg SA,. IL-2 administration increases CD4+ CD25(hi) Foxp3+ regulatory T cells in cancer patients. Blood 2006; 107: 2409-14.
-
(2006)
Blood
, vol.107
, pp. 2409-2414
-
-
Ahmadzadeh, M.1
Rosenberg, S.A.2
|