메뉴 건너뛰기




Volumn 8, Issue 1, 2017, Pages 40-53

The age-related eye disease 2 study: Micronutrients in the treatment of macular degeneration

Author keywords

AMD; AREDS2; Micronutrients; N 3 LC PUFAs; Xanthophylls; carotene

Indexed keywords

ANTIOXIDANT; TRACE ELEMENT; XANTHOPHYLL; ZEAXANTHIN;

EID: 85011300294     PISSN: 21618313     EISSN: 21565376     Source Type: Journal    
DOI: 10.3945/an.116.013177     Document Type: Review
Times cited : (96)

References (155)
  • 3
    • 84892965801 scopus 로고    scopus 로고
    • Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
    • Wong WL, Su X, Li X, Cheung CMG, Klein R, Cheng C-Y, Wong TY. Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis. Lancet Glob Health 2014;2:e106-16.
    • (2014) Lancet Glob Health , vol.2 , pp. e106-e116
    • Wong, W.L.1    Su, X.2    Li, X.3    Cheung, C.M.G.4    Klein, R.5    Cheng, C.-Y.6    Wong, T.Y.7
  • 4
    • 0029945201 scopus 로고    scopus 로고
    • Beta-carotene, carotenoids, and disease prevention in humans
    • Mayne ST. Beta-carotene, carotenoids, and disease prevention in humans. FASEB J 1996;10:690-701.
    • (1996) FASEB J , vol.10 , pp. 690-701
    • Mayne, S.T.1
  • 6
    • 0015445712 scopus 로고
    • Drusen and disciform macular detachment and degeneration
    • Gass JD. Drusen and disciform macular detachment and degeneration. Trans Am Ophthalmol Soc 1972;70:409-36.
    • (1972) Trans Am Ophthalmol Soc , vol.70 , pp. 409-436
    • Gass, J.D.1
  • 8
    • 0032797880 scopus 로고    scopus 로고
    • Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression
    • Abdelsalam A, Del Priore L, Zarbin MA. Drusen in age-related macular degeneration: pathogenesis, natural course, and laser photocoagulation-induced regression. Surv Ophthalmol 1999;44:1-29.
    • (1999) Surv Ophthalmol , vol.44 , pp. 1-29
    • Abdelsalam, A.1    Del Priore, L.2    Zarbin, M.A.3
  • 9
    • 0017583873 scopus 로고
    • Senile macular degeneration: a histopathologic study
    • Green WR, Key SN 3rd. Senile macular degeneration: a histopathologic study. Trans Am Ophthalmol Soc 1977;75:180-254.
    • (1977) Trans Am Ophthalmol Soc , vol.75 , pp. 180-254
    • Green, W.R.1    Key, S.N.2
  • 10
    • 0038708118 scopus 로고    scopus 로고
    • Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies
    • Ambati J, Ambati BK, Yoo SH, Ianchulev S, Adamis AP. Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv Ophthalmol 2003;48:257-93.
    • (2003) Surv Ophthalmol , vol.48 , pp. 257-293
    • Ambati, J.1    Ambati, B.K.2    Yoo, S.H.3    Ianchulev, S.4    Adamis, A.P.5
  • 11
    • 0022973508 scopus 로고
    • Choroidal neovascularization
    • Green WR, Wilson DJ. Choroidal neovascularization. Ophthalmology 1986;93:1169-76.
    • (1986) Ophthalmology , vol.93 , pp. 1169-1176
    • Green, W.R.1    Wilson, D.J.2
  • 12
    • 0021752680 scopus 로고
    • Age-related macular degeneration and blindness due to neovascular maculopathy
    • Ferris FL, Fine SL, Hyman L. Age-related macular degeneration and blindness due to neovascular maculopathy. Arch Ophthalmol 1984; 102:1640-2.
    • (1984) Arch Ophthalmol , vol.102 , pp. 1640-1642
    • Ferris, F.L.1    Fine, S.L.2    Hyman, L.3
  • 13
    • 34447634120 scopus 로고    scopus 로고
    • Treatment of exudative age-related macular degeneration: many factors to consider
    • Olsen TW, Knobloch WH. Treatment of exudative age-related macular degeneration: many factors to consider. Am J Ophthalmol 2007; 144:281-3.
    • (2007) Am J Ophthalmol , vol.144 , pp. 281-283
    • Olsen, T.W.1    Knobloch, W.H.2
  • 15
    • 1942542429 scopus 로고    scopus 로고
    • Age-related macular degeneration is the leading cause of blindness
    • Bressler NM. Age-related macular degeneration is the leading cause of blindness. JAMA 2004;291:1900-1.
    • (2004) JAMA , vol.291 , pp. 1900-1901
    • Bressler, N.M.1
  • 18
    • 0035128064 scopus 로고    scopus 로고
    • Risk factors for age-related macular degeneration
    • Evans JR. Risk factors for age-related macular degeneration. Prog Retin Eye Res 2001;20:227-53.
    • (2001) Prog Retin Eye Res , vol.20 , pp. 227-253
    • Evans, J.R.1
  • 20
    • 0024801823 scopus 로고
    • Age-related macular degeneration. Macular changes, prevalence and sex ratio. An epidemiological study of 1000 aged individuals
    • Vinding T. Age-related macular degeneration. Macular changes, prevalence and sex ratio. An epidemiological study of 1000 aged individuals. Acta Ophthalmol (Copenh) 1989;67:609-16.
    • (1989) Acta Ophthalmol (Copenh) , vol.67 , pp. 609-616
    • Vinding, T.1
  • 23
    • 0036100775 scopus 로고    scopus 로고
    • Five-year incidence of agerelated maculopathy lesions: the Blue Mountains Eye Study
    • Mitchell P, Wang JJ, Foran S, Smith W. Five-year incidence of agerelated maculopathy lesions: the Blue Mountains Eye Study. Ophthalmology 2002;109:1092-7.
    • (2002) Ophthalmology , vol.109 , pp. 1092-1097
    • Mitchell, P.1    Wang, J.J.2    Foran, S.3    Smith, W.4
  • 27
    • 0031738364 scopus 로고    scopus 로고
    • Iris color, skin sun sensitivity, and agerelated maculopathy: the Blue Mountains Eye Study
    • Mitchell P, Smith W, Wang JJ. Iris color, skin sun sensitivity, and agerelated maculopathy: the Blue Mountains Eye Study. Ophthalmology 1998;105:1359-63.
    • (1998) Ophthalmology , vol.105 , pp. 1359-1363
    • Mitchell, P.1    Smith, W.2    Wang, J.J.3
  • 28
    • 0031893363 scopus 로고    scopus 로고
    • The relationship of ocular factors to the incidence and progression of age-related maculopathy
    • Klein R, Klein BE, Jensen SC, Cruickshanks KJ. The relationship of ocular factors to the incidence and progression of age-related maculopathy. Arch Ophthalmol 1998;116:506-13.
    • (1998) Arch Ophthalmol , vol.116 , pp. 506-513
    • Klein, R.1    Klein, B.E.2    Jensen, S.C.3    Cruickshanks, K.J.4
  • 31
    • 77951477731 scopus 로고    scopus 로고
    • The role of complement Factor H in age-related macular degeneration: a review
    • Donoso LA, Vrabec T, Kuivaniemi H. The role of complement Factor H in age-related macular degeneration: a review. Surv Ophthalmol 2010;55:227-46.
    • (2010) Surv Ophthalmol , vol.55 , pp. 227-246
    • Donoso, L.A.1    Vrabec, T.2    Kuivaniemi, H.3
  • 35
    • 29744442338 scopus 로고    scopus 로고
    • Genetic Factors in AMDS. Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation
    • Khan JC, Thurlby DA, Shahid H, Clayton DG, Yates JR, Bradley M, Moore AT, Bird AC. Genetic Factors in AMDS. Smoking and age related macular degeneration: the number of pack years of cigarette smoking is a major determinant of risk for both geographic atrophy and choroidal neovascularisation. Br J Ophthalmol 2006;90:75-80.
    • (2006) Br J Ophthalmol , vol.90 , pp. 75-80
    • Khan, J.C.1    Thurlby, D.A.2    Shahid, H.3    Clayton, D.G.4    Yates, J.R.5    Bradley, M.6    Moore, A.T.7    Bird, A.C.8
  • 36
    • 0034793414 scopus 로고    scopus 로고
    • Light exposure and the risk of age-related macular degeneration: the Pathologies Oculaires Liees a l'Age (POLA) study
    • Delcourt C, Carriere I, Ponton-Sanchez A, Fourrey S, Lacroux A, Papoz L. Light exposure and the risk of age-related macular degeneration: the Pathologies Oculaires Liees a l'Age (POLA) study. Arch Ophthalmol 2001;119:1463-8.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1463-1468
    • Delcourt, C.1    Carriere, I.2    Ponton-Sanchez, A.3    Fourrey, S.4    Lacroux, A.5    Papoz, L.6
  • 39
    • 0027534867 scopus 로고
    • Sunlight and age-related macular degeneration. The Beaver Dam Eye Study
    • Cruickshanks KJ, Klein R, Klein BE. Sunlight and age-related macular degeneration. The Beaver Dam Eye Study. Arch Ophthalmol 1993; 111:514-8.
    • (1993) Arch Ophthalmol , vol.111 , pp. 514-518
    • Cruickshanks, K.J.1    Klein, R.2    Klein, B.E.3
  • 40
    • 0025298717 scopus 로고
    • Age-related changes in the morphology, absorption and fluorescence of melanosomes and lipofuscin granules of the retinal pigment epithelium
    • Boulton M, Docchio F, Dayhaw-Barker P, Ramponi R, Cubeddu R. Age-related changes in the morphology, absorption and fluorescence of melanosomes and lipofuscin granules of the retinal pigment epithelium. Vision Res 1990;30:1291-303.
    • (1990) Vision Res , vol.30 , pp. 1291-1303
    • Boulton, M.1    Docchio, F.2    Dayhaw-Barker, P.3    Ramponi, R.4    Cubeddu, R.5
  • 41
    • 0034769744 scopus 로고    scopus 로고
    • Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye
    • Bernstein PS, Khachik F, Carvalho LS, Muir GJ, Zhao DY, Katz NB. Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye. Exp Eye Res 2001;72:215-23.
    • (2001) Exp Eye Res , vol.72 , pp. 215-223
    • Bernstein, P.S.1    Khachik, F.2    Carvalho, L.S.3    Muir, G.J.4    Zhao, D.Y.5    Katz, N.B.6
  • 42
    • 62349128260 scopus 로고    scopus 로고
    • Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium
    • Bhosale P, Serban B, Bernstein PS. Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium. Arch Biochem Biophys 2009;483:175-81.
    • (2009) Arch Biochem Biophys , vol.483 , pp. 175-181
    • Bhosale, P.1    Serban, B.2    Bernstein, P.S.3
  • 43
    • 0034086115 scopus 로고    scopus 로고
    • The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells
    • Sparrow JR, Nakanishi K, Parish CA. The lipofuscin fluorophore A2E mediates blue light-induced damage to retinal pigmented epithelial cells. Invest Ophthalmol Vis Sci 2000;41:1981-9.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , pp. 1981-1989
    • Sparrow, J.R.1    Nakanishi, K.2    Parish, C.A.3
  • 45
    • 84863726788 scopus 로고    scopus 로고
    • Consequences of oxidative stress in agerelated macular degeneration
    • Jarrett SG, Boulton ME. Consequences of oxidative stress in agerelated macular degeneration. Mol Aspects Med 2012;33:399-417.
    • (2012) Mol Aspects Med , vol.33 , pp. 399-417
    • Jarrett, S.G.1    Boulton, M.E.2
  • 46
    • 0027397668 scopus 로고
    • Antioxidant status and neovascular age-related macular degeneration
    • Erratum in: Arch Ophthalmol 1993;111:1499; 111:1228; 111: 1366
    • Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group. Arch Ophthalmol 1993;111: 104-9. Erratum in: Arch Ophthalmol 1993;111:1499; 111:1228; 111: 1366.
    • (1993) Arch Ophthalmol , vol.111 , pp. 104-109
  • 48
    • 84955419184 scopus 로고    scopus 로고
    • Lutein, zeaxanthin, and meso-zeaxanthin: the basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease
    • Bernstein PS, Li B, Vachali PP, Gorusupudi A, Shyam R, Henriksen BS, Nolan JM. Lutein, zeaxanthin, and meso-zeaxanthin: the basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease. Prog Retin Eye Res 2016;50:34-66.
    • (2016) Prog Retin Eye Res , vol.50 , pp. 34-66
    • Bernstein, P.S.1    Li, B.2    Vachali, P.P.3    Gorusupudi, A.4    Shyam, R.5    Henriksen, B.S.6    Nolan, J.M.7
  • 53
    • 0032527738 scopus 로고    scopus 로고
    • Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study
    • VandenLangenberg GM, Mares-Perlman JA, Klein R, Klein BE, Brady WE, Palta M. Associations between antioxidant and zinc intake and the 5-year incidence of early age-related maculopathy in the Beaver Dam Eye Study. Am J Epidemiol 1998;148:204-14.
    • (1998) Am J Epidemiol , vol.148 , pp. 204-214
    • VandenLangenberg, G.M.1    Mares-Perlman, J.A.2    Klein, R.3    Klein, B.E.4    Brady, W.E.5    Palta, M.6
  • 55
    • 0033499069 scopus 로고    scopus 로고
    • Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study
    • Smith W, Mitchell P, Webb K, Leeder SR. Dietary antioxidants and age-related maculopathy: the Blue Mountains Eye Study. Ophthalmology 1999;106:761-7.
    • (1999) Ophthalmology , vol.106 , pp. 761-767
    • Smith, W.1    Mitchell, P.2    Webb, K.3    Leeder, S.R.4
  • 56
    • 0034800655 scopus 로고    scopus 로고
    • A randomized, placebocontrolled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report No. 8
    • Age-Related Eye Disease Study Research Group. A randomized, placebocontrolled, clinical trial of high-dose supplementation with vitamins C and E, beta carotene, and zinc for age-related macular degeneration and vision loss: AREDS report No. 8. Arch Ophthalmol 2001;119:1417-36.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1417-1436
  • 58
    • 0035283350 scopus 로고    scopus 로고
    • Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey
    • Mares-Perlman JA, Fisher AI, Klein R, Palta M, Block G, Millen AE, Wright JD. Lutein and zeaxanthin in the diet and serum and their relation to age-related maculopathy in the third national health and nutrition examination survey. Am J Epidemiol 2001;153:424-32.
    • (2001) Am J Epidemiol , vol.153 , pp. 424-432
    • Mares-Perlman, J.A.1    Fisher, A.I.2    Klein, R.3    Palta, M.4    Block, G.5    Millen, A.E.6    Wright, J.D.7
  • 61
    • 2542432254 scopus 로고    scopus 로고
    • Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial)
    • Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, TsipurskyM, Nyland J. Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration: the Veterans LAST study (Lutein Antioxidant Supplementation Trial). Optometry 2004;75:216-30.
    • (2004) Optometry , vol.75 , pp. 216-230
    • Richer, S.1    Stiles, W.2    Statkute, L.3    Pulido, J.4    Frankowski, J.5    Rudy, D.6    Pei, K.7    Tsipursky, M.8    Nyland, J.9
  • 63
    • 33745673024 scopus 로고    scopus 로고
    • Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA study
    • Delcourt C, Carrière I, Delage M, Barberger-Gateau P, Schalch W. Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA study. Invest Ophthalmol Vis Sci 2006;47:2329-35.
    • (2006) Invest Ophthalmol Vis Sci , vol.47 , pp. 2329-2335
    • Delcourt, C.1    Carrière, I.2    Delage, M.3    Barberger-Gateau, P.4    Schalch, W.5
  • 64
    • 33747185607 scopus 로고    scopus 로고
    • Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the carotenoids in Age-Related Eye Disease Study (CAREDS): ancillary study of the Women's Health Initiative
    • Moeller SM, Parekh N, Tinker L, Ritenbaugh C, Blodi B, Wallace RB, Mares JA; CAREDS Research Study Group. Associations between intermediate age-related macular degeneration and lutein and zeaxanthin in the carotenoids in Age-Related Eye Disease Study (CAREDS): ancillary study of the Women's Health Initiative. Arch Ophthalmol 2006;124:1151-62.
    • (2006) Arch Ophthalmol , vol.124 , pp. 1151-1162
    • Moeller, S.M.1    Parekh, N.2    Tinker, L.3    Ritenbaugh, C.4    Blodi, B.5    Wallace, R.B.6    Mares, J.A.7
  • 65
    • 33745839872 scopus 로고    scopus 로고
    • Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: The US twin study of age-related macular degeneration
    • Seddon JM, George S, Rosner B. Cigarette smoking, fish consumption, omega-3 fatty acid intake, and associations with age-related macular degeneration: The US twin study of age-related macular degeneration. Arch Ophthalmol 2006;124:995-1001.
    • (2006) Arch Ophthalmol , vol.124 , pp. 995-1001
    • Seddon, J.M.1    George, S.2    Rosner, B.3
  • 66
    • 34548650913 scopus 로고    scopus 로고
    • The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22
    • Age-Related Eye Disease Study Research Group; SanGiovanni JP, Chew EY, Clemons TE, Ferris FL 3rd, Gensler G, Lindblad AS, Milton RC, Seddon JM, Sperduto RD. The relationship of dietary carotenoid and vitamin A, E, and C intake with age-related macular degeneration in a case-control study: AREDS Report No. 22. Arch Ophthalmol 2007;125:1225-32.
    • (2007) Arch Ophthalmol , vol.125 , pp. 1225-1232
    • SanGiovanni, J.P.1    Chew, E.Y.2    Clemons, T.E.3    Ferris, F.L.4    Gensler, G.5    Lindblad, A.S.6    Milton, R.C.7    Seddon, J.M.8    Sperduto, R.D.9
  • 67
    • 33947190545 scopus 로고    scopus 로고
    • Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: the LUNA study
    • Trieschmann M, Beatty S, Nolan JM, Hense HW, Heimes B, Austermann U, Fobker M, PauleikhoffD. Changes in macular pigment optical density and serum concentrations of its constituent carotenoids following supplemental lutein and zeaxanthin: the LUNA study. Exp Eye Res 2007;84:718-28.
    • (2007) Exp Eye Res , vol.84 , pp. 718-728
    • Trieschmann, M.1    Beatty, S.2    Nolan, J.M.3    Hense, H.W.4    Heimes, B.5    Austermann, U.6    Fobker, M.7    Pauleikhoff, D.8
  • 68
    • 45749102775 scopus 로고    scopus 로고
    • Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration
    • Cho E, Hankinson SE, Rosner B, Willett WC, Colditz GA. Prospective study of lutein/zeaxanthin intake and risk of age-related macular degeneration. Am J Clin Nutr 2008;87:1837-43.
    • (2008) Am J Clin Nutr , vol.87 , pp. 1837-1843
    • Cho, E.1    Hankinson, S.E.2    Rosner, B.3    Willett, W.C.4    Colditz, G.A.5
  • 69
    • 38749097003 scopus 로고    scopus 로고
    • Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study
    • Tan JS, Wang JJ, Flood V, Rochtchina E, Smith W, Mitchell P. Dietary antioxidants and the long-term incidence of age-related macular degeneration: the Blue Mountains Eye Study. Ophthalmology 2008; 115:334-41.
    • (2008) Ophthalmology , vol.115 , pp. 334-341
    • Tan, J.S.1    Wang, J.J.2    Flood, V.3    Rochtchina, E.4    Smith, W.5    Mitchell, P.6
  • 70
    • 70449719060 scopus 로고    scopus 로고
    • Association between dietary fat intake and age-related macular degeneration in the carotenoids in Age-Related Eye Disease Study (CAREDS): An ancillary study of the women's health initiative
    • Parekh N, Voland RP, Moeller SM, Blodi BA, Ritenbaugh C, Chappell RJ, Wallace RB, Mares JA; CAREDS Research Study Group. Association between dietary fat intake and age-related macular degeneration in the carotenoids in Age-Related Eye Disease Study (CAREDS): An ancillary study of the women's health initiative. Arch Ophthalmol 2009;127:1483-93.
    • (2009) Arch Ophthalmol , vol.127 , pp. 1483-1493
    • Parekh, N.1    Voland, R.P.2    Moeller, S.M.3    Blodi, B.A.4    Ritenbaugh, C.5    Chappell, R.J.6    Wallace, R.B.7    Mares, J.A.8
  • 72
    • 84881144615 scopus 로고    scopus 로고
    • Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: the Nutritional AMD Treatment 2 Study
    • Souied EH, Delcourt C, Querques G, Bassols A, Merle B, Zourdani A, Smith T, Benlian P. Oral docosahexaenoic acid in the prevention of exudative age-related macular degeneration: the Nutritional AMD Treatment 2 Study. Ophthalmology 2013;120:1619-31.
    • (2013) Ophthalmology , vol.120 , pp. 1619-1631
    • Souied, E.H.1    Delcourt, C.2    Querques, G.3    Bassols, A.4    Merle, B.5    Zourdani, A.6    Smith, T.7    Benlian, P.8
  • 73
    • 84891484792 scopus 로고    scopus 로고
    • Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study
    • Dawczynski J, Jentsch S, Schweitzer D, Hammer M, Lang GE, Strobel J. Long term effects of lutein, zeaxanthin and omega-3-LCPUFAs supplementation on optical density of macular pigment in AMD patients: the LUTEGA study. Graefes Arch Clin Exp Ophthalmol 2013;251:2711-23.
    • (2013) Graefes Arch Clin Exp Ophthalmol , vol.251 , pp. 2711-2723
    • Dawczynski, J.1    Jentsch, S.2    Schweitzer, D.3    Hammer, M.4    Lang, G.E.5    Strobel, J.6
  • 74
    • 79955038329 scopus 로고    scopus 로고
    • Implications of altered iron homeostasis for age-related macular degeneration
    • Blasiak J, Szaflik J, Szaflik JP. Implications of altered iron homeostasis for age-related macular degeneration. Front Biosci (Landmark Ed) 2011;16:1551-9.
    • (2011) Front Biosci (Landmark Ed) , vol.16 , pp. 1551-1559
    • Blasiak, J.1    Szaflik, J.2    Szaflik, J.P.3
  • 77
    • 0026743430 scopus 로고
    • Interaction of Fe3+, Cu2+ and Zn2+ with melanin and melanoproteins from bovine eyes
    • Andrzejczyk J, Buszman E. Interaction of Fe3+, Cu2+ and Zn2+ with melanin and melanoproteins from bovine eyes. Acta Biochim Pol 1992;39:85-8.
    • (1992) Acta Biochim Pol , vol.39 , pp. 85-88
    • Andrzejczyk, J.1    Buszman, E.2
  • 78
    • 0040430919 scopus 로고
    • Distribution of copper and zinc in mammalian eyes. Occurrence of metals in melanin fractions from eye tissues
    • Bowness JM, Morton RA, Shakir MH, Stubbs AL. Distribution of copper and zinc in mammalian eyes. Occurrence of metals in melanin fractions from eye tissues. Biochem J 1952;51:521.
    • (1952) Biochem J , vol.51 , pp. 521
    • Bowness, J.M.1    Morton, R.A.2    Shakir, M.H.3    Stubbs, A.L.4
  • 79
    • 58249104078 scopus 로고    scopus 로고
    • Reduced zinc and copper in the retinal pigment epithelium and choroid in age-related macular degeneration
    • Erie JC, Good JA, Butz JA, Pulido JS. Reduced zinc and copper in the retinal pigment epithelium and choroid in age-related macular degeneration. Am J Ophthalmol 2009;147:276-82.e1.
    • (2009) Am J Ophthalmol , vol.147 , pp. 276.e1-282.e1
    • Erie, J.C.1    Good, J.A.2    Butz, J.A.3    Pulido, J.S.4
  • 80
    • 68549135352 scopus 로고    scopus 로고
    • Acute and bilateral blindness due to optic neuropathy associated with copper deficiency
    • Naismith RT, Shepherd JB, Weihl CC, Tutlam NT, Cross AH. Acute and bilateral blindness due to optic neuropathy associated with copper deficiency. Arch Neurol 2009;66:1025-7.
    • (2009) Arch Neurol , vol.66 , pp. 1025-1027
    • Naismith, R.T.1    Shepherd, J.B.2    Weihl, C.C.3    Tutlam, N.T.4    Cross, A.H.5
  • 82
    • 84920714021 scopus 로고    scopus 로고
    • Five heavy metallic elements and age-related macular degeneration
    • Park SJ, Lee JH, Woo SJ, Kang SW, Park KH. Five heavy metallic elements and age-related macular degeneration. Ophthalmology 2015; 122:129-37.
    • (2015) Ophthalmology , vol.122 , pp. 129-137
    • Park, S.J.1    Lee, J.H.2    Woo, S.J.3    Kang, S.W.4    Park, K.H.5
  • 83
    • 84886925646 scopus 로고    scopus 로고
    • Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD)
    • Tokarz P, Kaarniranta K, Blasiak J. Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD). Biogerontology 2013;14:461-82.
    • (2013) Biogerontology , vol.14 , pp. 461-482
    • Tokarz, P.1    Kaarniranta, K.2    Blasiak, J.3
  • 84
    • 45249084304 scopus 로고    scopus 로고
    • Manganese superoxide dismutase gene (SOD2) polymorphism and exudative agerelated macular degeneration in the Japanese population
    • author reply146-7
    • Gotoh N, Yamada R, Matsuda F, Yoshimura N, Iida T. Manganese superoxide dismutase gene (SOD2) polymorphism and exudative agerelated macular degeneration in the Japanese population. Am J Ophthalmol 2008;146:author reply146-7.
    • (2008) Am J Ophthalmol , vol.146
    • Gotoh, N.1    Yamada, R.2    Matsuda, F.3    Yoshimura, N.4    Iida, T.5
  • 86
    • 0023836483 scopus 로고
    • The regional distribution of vitamins E and C in mature and premature human retinas
    • Nielsen JC, Naash MI, Anderson RE. The regional distribution of vitamins E and C in mature and premature human retinas. Invest Ophthalmol Vis Sci 1988;29:22-6.
    • (1988) Invest Ophthalmol Vis Sci , vol.29 , pp. 22-26
    • Nielsen, J.C.1    Naash, M.I.2    Anderson, R.E.3
  • 88
    • 0020284922 scopus 로고
    • The roles of vitamin E and unsaturated fatty acids in the visual process
    • Robison WG Jr., Kuwabara T, Bieri JG. The roles of vitamin E and unsaturated fatty acids in the visual process. Retina 1982;2:263-81.
    • (1982) Retina , vol.2 , pp. 263-281
    • Robison, W.G.1    Kuwabara, T.2    Bieri, J.G.3
  • 90
    • 0024501240 scopus 로고
    • Failure of vitamin E to protect the retina against damage resulting from bright cyclic light exposure
    • Katz ML, Eldred GE. Failure of vitamin E to protect the retina against damage resulting from bright cyclic light exposure. Invest Ophthalmol Vis Sci 1989;30:29-36.
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 29-36
    • Katz, M.L.1    Eldred, G.E.2
  • 91
    • 0024561018 scopus 로고
    • Retinal light damage reduces autofluorescent pigment deposition in the retinal pigment epithelium
    • Katz ML, Eldred GE. Retinal light damage reduces autofluorescent pigment deposition in the retinal pigment epithelium. Invest Ophthalmol Vis Sci 1989;30:37-43.
    • (1989) Invest Ophthalmol Vis Sci , vol.30 , pp. 37-43
    • Katz, M.L.1    Eldred, G.E.2
  • 92
    • 0033104682 scopus 로고    scopus 로고
    • Romá J, Vilela C, Puertas FJ, Díaz-Llopis M, Bosch-Morell F, Romero FJ. Serum vitamin E levels negatively correlate with severity of age-related macular degeneration
    • Belda JI. Romá J, Vilela C, Puertas FJ, Díaz-Llopis M, Bosch-Morell F, Romero FJ. Serum vitamin E levels negatively correlate with severity of age-related macular degeneration. Mech Ageing Dev 1999;107:159-64.
    • (1999) Mech Ageing Dev , vol.107 , pp. 159-164
    • Belda, J.I.1
  • 93
    • 0037031048 scopus 로고    scopus 로고
    • Vitamin E supplementation and macular degeneration: randomised controlled trial
    • Taylor HR, Tikellis G, Robman LD, McCarty CA, McNeil JJ. Vitamin E supplementation and macular degeneration: randomised controlled trial. BMJ 2002;325:11.
    • (2002) BMJ , vol.325 , pp. 11
    • Taylor, H.R.1    Tikellis, G.2    Robman, L.D.3    McCarty, C.A.4    McNeil, J.J.5
  • 94
    • 61549126593 scopus 로고    scopus 로고
    • Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study
    • Christen WG, Glynn RJ, Chew EY, Albert CM, Manson JE. Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study. Arch Intern Med 2009;169:335-41.
    • (2009) Arch Intern Med , vol.169 , pp. 335-341
    • Christen, W.G.1    Glynn, R.J.2    Chew, E.Y.3    Albert, C.M.4    Manson, J.E.5
  • 95
    • 84879440336 scopus 로고    scopus 로고
    • Homocysteine, folate, vitamin B-12, and 10-y incidence of age-related macular degeneration
    • Gopinath B, Flood VM, Rochtchina E, Wang JJ, Mitchell P. Homocysteine, folate, vitamin B-12, and 10-y incidence of age-related macular degeneration. Am J Clin Nutr 2013;98:129-35.
    • (2013) Am J Clin Nutr , vol.98 , pp. 129-135
    • Gopinath, B.1    Flood, V.M.2    Rochtchina, E.3    Wang, J.J.4    Mitchell, P.5
  • 96
    • 0029598850 scopus 로고
    • Structure and properties of carotenoids in relation to function
    • Britton G. Structure and properties of carotenoids in relation to function. FASEB J 1995;9:1551-8.
    • (1995) FASEB J , vol.9 , pp. 1551-1558
    • Britton, G.1
  • 97
    • 0031418651 scopus 로고    scopus 로고
    • Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching
    • Stahl W, Nicolai S, Briviba K, Hanusch M, Broszeit G, Peters M, Martin HD, Sies H. Biological activities of natural and synthetic carotenoids: induction of gap junctional communication and singlet oxygen quenching. Carcinogenesis 1997;18:89-92.
    • (1997) Carcinogenesis , vol.18 , pp. 89-92
    • Stahl, W.1    Nicolai, S.2    Briviba, K.3    Hanusch, M.4    Broszeit, G.5    Peters, M.6    Martin, H.D.7    Sies, H.8
  • 98
    • 0021362463 scopus 로고
    • beta-Carotene: an unusual type of lipid antioxidant
    • Burton GW, Ingold KU. beta-Carotene: an unusual type of lipid antioxidant. Science 1984;224:569-73.
    • (1984) Science , vol.224 , pp. 569-573
    • Burton, G.W.1    Ingold, K.U.2
  • 101
    • 0027938689 scopus 로고
    • Oxy-radicals and cancer
    • Cerutti PA. Oxy-radicals and cancer. Lancet 1994;344:862-3.
    • (1994) Lancet , vol.344 , pp. 862-863
    • Cerutti, P.A.1
  • 102
    • 16244368037 scopus 로고    scopus 로고
    • Risk factors for the incidence of advanced age-related macular degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19
    • Clemons TE, Milton RC, Klein R, Seddon JM, Ferris, FL 3rd; Age-Related Eye Disease Study Research Group. Risk factors for the incidence of advanced age-related macular degeneration in the Age-Related Eye Disease Study (AREDS) AREDS report no. 19. Ophthalmology 2005; 112:533-9.
    • (2005) Ophthalmology , vol.112 , pp. 533-539
    • Clemons, T.E.1    Milton, R.C.2    Klein, R.3    Seddon, J.M.4    Ferris, F.L.5
  • 103
    • 0034788401 scopus 로고    scopus 로고
    • A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9
    • Age-Related Eye Disease Study Research Group. A randomized, placebo-controlled, clinical trial of high-dose supplementation with vitamins C and E and beta carotene for age-related cataract and vision loss: AREDS report no. 9. Arch Ophthalmol 2001;119:1439-52.
    • (2001) Arch Ophthalmol , vol.119 , pp. 1439-1452
  • 104
    • 10344238570 scopus 로고    scopus 로고
    • Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance
    • Albanes D, Heinonen OP, Taylor PR, Virtamo J, Edwards BK, Rautalahti M, Hartman AM, Palmgren J, Freedman LS, Haapakoski J, et al. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 1996;88:1560-70.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1560-1570
    • Albanes, D.1    Heinonen, O.P.2    Taylor, P.R.3    Virtamo, J.4    Edwards, B.K.5    Rautalahti, M.6    Hartman, A.M.7    Palmgren, J.8    Freedman, L.S.9    Haapakoski, J.10
  • 105
    • 0010607277 scopus 로고
    • The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers
    • The Alpha-Tocopherol Beta Carotene Cancer Prevention Study Group. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. N Engl J Med 1994;330:1029-35.
    • (1994) N Engl J Med , vol.330 , pp. 1029-1035
  • 108
    • 0028879019 scopus 로고
    • Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins
    • Snodderly DM. Evidence for protection against age-related macular degeneration by carotenoids and antioxidant vitamins. Am J Clin Nutr 1995;62:1448S-61S.
    • (1995) Am J Clin Nutr , vol.62 , pp. 1448S-1461S
    • Snodderly, D.M.1
  • 109
    • 0036845558 scopus 로고    scopus 로고
    • Transformations of selected carotenoids in plasma, liver, and ocular tissues of humans and in nonprimate animal models
    • Khachik F, de Moura FF, Zhao DY, Aebischer CP, Bernstein PS. Transformations of selected carotenoids in plasma, liver, and ocular tissues of humans and in nonprimate animal models. Invest Ophthalmol Vis Sci 2002;43:3383-92.
    • (2002) Invest Ophthalmol Vis Sci , vol.43 , pp. 3383-3392
    • Khachik, F.1    de Moura, F.F.2    Zhao, D.Y.3    Aebischer, C.P.4    Bernstein, P.S.5
  • 110
    • 0035879765 scopus 로고    scopus 로고
    • Lipofuscin-formation in retinal pigment epithelial cells is reduced by antioxidants
    • Sundelin SP, Nilsson SE. Lipofuscin-formation in retinal pigment epithelial cells is reduced by antioxidants. Free Radic Biol Med 2001;31: 217-25.
    • (2001) Free Radic Biol Med , vol.31 , pp. 217-225
    • Sundelin, S.P.1    Nilsson, S.E.2
  • 111
    • 0034770149 scopus 로고    scopus 로고
    • Carotenoids in the retina and lens: possible acute and chronic effects on human visual performance
    • Hammond BR Jr., Wooten BR, Curran-Celentano J. Carotenoids in the retina and lens: possible acute and chronic effects on human visual performance. Arch Biochem Biophys 2001;385:41-6.
    • (2001) Arch Biochem Biophys , vol.385 , pp. 41-46
    • Hammond, B.R.1    Wooten, B.R.2    Curran-Celentano, J.3
  • 112
    • 39849091480 scopus 로고    scopus 로고
    • Macular pigment and visual performance under glare conditions
    • Stringham JM, Hammond BR. Macular pigment and visual performance under glare conditions. Optom Vis Sci 2008;85:82-8.
    • (2008) Optom Vis Sci , vol.85 , pp. 82-88
    • Stringham, J.M.1    Hammond, B.R.2
  • 113
    • 79953206938 scopus 로고    scopus 로고
    • Identification of StARD3 as a lutein-binding protein in the macula of the primate retina
    • Li B, Vachali P, Frederick JM, Bernstein PS. Identification of StARD3 as a lutein-binding protein in the macula of the primate retina. Biochemistry 2011;50:2541-9.
    • (2011) Biochemistry , vol.50 , pp. 2541-2549
    • Li, B.1    Vachali, P.2    Frederick, J.M.3    Bernstein, P.S.4
  • 114
    • 10344229953 scopus 로고    scopus 로고
    • Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye
    • Bhosale P, Larson AJ, Frederick JM, Southwick K, Thulin CD, Bernstein PS. Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye. J Biol Chem 2004;279:49447-54.
    • (2004) J Biol Chem , vol.279 , pp. 49447-49454
    • Bhosale, P.1    Larson, A.J.2    Frederick, J.M.3    Southwick, K.4    Thulin, C.D.5    Bernstein, P.S.6
  • 116
    • 68549133536 scopus 로고    scopus 로고
    • Bioavailability of non-provitamin A carotenoids
    • Bohn T. Bioavailability of non-provitamin A carotenoids. Curr Nutr Food Sci 2008;4:240-58.
    • (2008) Curr Nutr Food Sci , vol.4 , pp. 240-258
    • Bohn, T.1
  • 117
    • 33847781431 scopus 로고    scopus 로고
    • Effect of dietary lutein and zeaxanthin on plasma carotenoids and their transport in lipoproteins in age-related macular degeneration
    • Wang W, Connor SL, Johnson EJ, Klein ML, Hughes S, Connor WE. Effect of dietary lutein and zeaxanthin on plasma carotenoids and their transport in lipoproteins in age-related macular degeneration. Am J Clin Nutr 2007;85:762-9.
    • (2007) Am J Clin Nutr , vol.85 , pp. 762-769
    • Wang, W.1    Connor, S.L.2    Johnson, E.J.3    Klein, M.L.4    Hughes, S.5    Connor, W.E.6
  • 118
    • 0032850377 scopus 로고    scopus 로고
    • Accumulation and retention of micellar b-carotene and lutein by Caco-2 human intestinal cells
    • Garrett DA, Failla ML, Sarama RJ, Craft N. Accumulation and retention of micellar b-carotene and lutein by Caco-2 human intestinal cells. J Nutr Biochem 1999;10:573-81.
    • (1999) J Nutr Biochem , vol.10 , pp. 573-581
    • Garrett, D.A.1    Failla, M.L.2    Sarama, R.J.3    Craft, N.4
  • 119
    • 0031750412 scopus 로고    scopus 로고
    • Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men
    • van den Berg H, van Vliet T. Effect of simultaneous, single oral doses of beta-carotene with lutein or lycopene on the beta-carotene and retinyl ester responses in the triacylglycerol-rich lipoprotein fraction of men. Am J Clin Nutr 1998;68:82-9.
    • (1998) Am J Clin Nutr , vol.68 , pp. 82-89
    • van den Berg, H.1    van Vliet, T.2
  • 120
    • 20444403376 scopus 로고    scopus 로고
    • Challenges to understanding and measuring carotenoid bioavailability
    • Faulks RM, Southon S. Challenges to understanding and measuring carotenoid bioavailability. Biochim Biophys Acta 2005; 1740:95-100.
    • (2005) Biochim Biophys Acta , vol.1740 , pp. 95-100
    • Faulks, R.M.1    Southon, S.2
  • 121
    • 77955850288 scopus 로고    scopus 로고
    • Competitive inhibition of carotenoid transport and tissue concentrations by high dose supplements of lutein, zeaxanthin and beta-carotene
    • Wang Y, Illingworth DR, Connor SL, Duell PB, Connor WE. Competitive inhibition of carotenoid transport and tissue concentrations by high dose supplements of lutein, zeaxanthin and beta-carotene. Eur J Nutr 2010;49:327-36.
    • (2010) Eur J Nutr , vol.49 , pp. 327-336
    • Wang, Y.1    Illingworth, D.R.2    Connor, S.L.3    Duell, P.B.4    Connor, W.E.5
  • 122
    • 8844256502 scopus 로고    scopus 로고
    • The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina
    • SanGiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog Retin Eye Res 2005;24:87-138.
    • (2005) Prog Retin Eye Res , vol.24 , pp. 87-138
    • SanGiovanni, J.P.1    Chew, E.Y.2
  • 124
    • 0032819001 scopus 로고    scopus 로고
    • Essential fatty acids in health and chronic disease
    • Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr 1999;70:560S-9S.
    • (1999) Am J Clin Nutr , vol.70 , pp. 560S-569S
    • Simopoulos, A.P.1
  • 125
    • 84938090122 scopus 로고    scopus 로고
    • Indications for omega-3 long chain polyunsaturated fatty acid in the prevention and treatment of cardiovascular disease
    • Nestel P, Clifton P, Colquhoun D, Noakes M, Mori TA, Sullivan D, Thomas B. Indications for omega-3 long chain polyunsaturated fatty acid in the prevention and treatment of cardiovascular disease. Heart Lung Circ 2015;24:769-79.
    • (2015) Heart Lung Circ , vol.24 , pp. 769-779
    • Nestel, P.1    Clifton, P.2    Colquhoun, D.3    Noakes, M.4    Mori, T.A.5    Sullivan, D.6    Thomas, B.7
  • 126
    • 77954879552 scopus 로고    scopus 로고
    • Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol
    • EFSA Panel on Dietetic Products Nutrition, and Allergies. Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA J 2010;8: 1461.
    • (2010) EFSA J , vol.8 , pp. 1461
  • 128
    • 85011304802 scopus 로고    scopus 로고
    • Dietary lipid intake and incident advanced age-related macular degeneration (AMD) in the Age-Related Eye Disease Study (AREDS)
    • SanGiovanni J, Chew E, Clemons T, Seddon J, Klein R, AREDS Research. Dietary lipid intake and incident advanced age-related macular degeneration (AMD) in the Age-Related Eye Disease Study (AREDS). Invest Ophthalmol Vis Sci 2005;46:2382.
    • (2005) Invest Ophthalmol Vis Sci , vol.46 , pp. 2382
    • SanGiovanni, J.1    Chew, E.2    Clemons, T.3    Seddon, J.4    Klein, R.5
  • 129
    • 66349115906 scopus 로고    scopus 로고
    • Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease
    • Bazan NG. Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease. J Lipid Res 2009;50:S400-5.
    • (2009) J Lipid Res , vol.50 , pp. S400-S405
    • Bazan, N.G.1
  • 130
    • 33144459399 scopus 로고    scopus 로고
    • The role of inflammation in the pathogenesis of age-related macular degeneration
    • Donoso LA, Kim D, Frost A, Callahan A, Hageman G. The role of inflammation in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 2006;51:137-52.
    • (2006) Surv Ophthalmol , vol.51 , pp. 137-152
    • Donoso, L.A.1    Kim, D.2    Frost, A.3    Callahan, A.4    Hageman, G.5
  • 132
    • 60149101211 scopus 로고    scopus 로고
    • Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort
    • Wang JJ, Rochtchina E, Smith W, Klein R, Klein BE, Joshi T, Sivakumaran TA, Iyengar S, Mitchell P. Combined effects of complement factor H genotypes, fish consumption, and inflammatory markers on long-term risk for age-related macular degeneration in a cohort. Am J Epidemiol 2009;169:633-41.
    • (2009) Am J Epidemiol , vol.169 , pp. 633-641
    • Wang, J.J.1    Rochtchina, E.2    Smith, W.3    Klein, R.4    Klein, B.E.5    Joshi, T.6    Sivakumaran, T.A.7    Iyengar, S.8    Mitchell, P.9
  • 133
  • 134
    • 65649127117 scopus 로고    scopus 로고
    • Dietary fatty acids and the 10-year incidence of age-related macular degeneration: the Blue Mountains Eye Study
    • Tan JS, Wang JJ, Flood V, Mitchell P. Dietary fatty acids and the 10-year incidence of age-related macular degeneration: the Blue Mountains Eye Study. Arch Ophthalmol 2009;127:656-65.
    • (2009) Arch Ophthalmol , vol.127 , pp. 656-665
    • Tan, J.S.1    Wang, J.J.2    Flood, V.3    Mitchell, P.4
  • 135
    • 58449127323 scopus 로고    scopus 로고
    • v-3 long-chain polyunsaturated fatty acid intake inversely associated with 12-year progression to advanced age-related macular degeneration
    • SanGiovanni JP, Agrón E, Clemons TE, Chew EY. v-3 long-chain polyunsaturated fatty acid intake inversely associated with 12-year progression to advanced age-related macular degeneration. Arch Ophthalmol 2009;127:110-2.
    • (2009) Arch Ophthalmol , vol.127 , pp. 110-112
    • SanGiovanni, J.P.1    Agrón, E.2    Clemons, T.E.3    Chew, E.Y.4
  • 137
    • 84963865082 scopus 로고    scopus 로고
    • Associations of human retinal very long-chain polyunsaturated fatty acids with dietary lipid biomarkers
    • Gorusupudi A, Liu A, Hageman GS, Bernstein PS. Associations of human retinal very long-chain polyunsaturated fatty acids with dietary lipid biomarkers. J Lipid Res 2016;57:499-508.
    • (2016) J Lipid Res , vol.57 , pp. 499-508
    • Gorusupudi, A.1    Liu, A.2    Hageman, G.S.3    Bernstein, P.S.4
  • 138
    • 69249105050 scopus 로고    scopus 로고
    • Nutritional AMD treatment phase I (NAT-1): feasibility of oral DHA supplementation in age-related macular degeneration
    • Querques G, Benlian P, Chanu B, Portal C, Coscas G, Soubrane G, Souied E. Nutritional AMD treatment phase I (NAT-1): feasibility of oral DHA supplementation in age-related macular degeneration. Eur J Ophthalmol 2009;19:100.
    • (2009) Eur J Ophthalmol , vol.19 , pp. 100
    • Querques, G.1    Benlian, P.2    Chanu, B.3    Portal, C.4    Coscas, G.5    Soubrane, G.6    Souied, E.7
  • 140
    • 33846013969 scopus 로고    scopus 로고
    • High dose zinc increases hospital admissions due to genitourinary complications
    • Johnson AR, Munoz A, Gottlieb JL, Jarrard DF. High dose zinc increases hospital admissions due to genitourinary complications. J Urol 2007;177:639-43.
    • (2007) J Urol , vol.177 , pp. 639-643
    • Johnson, A.R.1    Munoz, A.2    Gottlieb, J.L.3    Jarrard, D.F.4
  • 141
  • 143
    • 84877734641 scopus 로고    scopus 로고
    • Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial
    • Erratum in: JAMA 2013;310:208
    • Age-Related Eye Disease Study 2 Research Group. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA 2013;309:2005-15.Erratum in: JAMA 2013;310:208.
    • (2013) JAMA , vol.309 , pp. 2005-2015
  • 144
    • 84894229056 scopus 로고    scopus 로고
    • Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3
    • Age-Related Eye Disease Study 2 Research Group, Chew EY, Clemons TE, Sangiovanni JP, Danis RP, Ferris FL III, Elman MJ, Antoszyk AN, Ruby AJ, Orth D, et al. Secondary analyses of the effects of lutein/zeaxanthin on age-related macular degeneration progression: AREDS2 report No. 3. JAMA Ophthalmol 2014;132:142-9.
    • (2014) JAMA Ophthalmol , vol.132 , pp. 142-149
    • Chew, E.Y.1    Clemons, T.E.2    Sangiovanni, J.P.3    Danis, R.P.4    Ferris, F.L.5    Elman, M.J.6    Antoszyk, A.N.7    Ruby, A.J.8    Orth, D.9
  • 149
    • 84920738808 scopus 로고    scopus 로고
    • Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study
    • Awh CC, Hawken S, Zanke BW. Treatment response to antioxidants and zinc based on CFH and ARMS2 genetic risk allele number in the Age-Related Eye Disease Study. Ophthalmology 2015;122:162-9.
    • (2015) Ophthalmology , vol.122 , pp. 162-169
    • Awh, C.C.1    Hawken, S.2    Zanke, B.W.3
  • 150
    • 84920747114 scopus 로고    scopus 로고
    • Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test?
    • Chew EY, Klein ML, Clemons TE, Agron E, Abecasis GR. Genetic testing in persons with age-related macular degeneration and the use of the AREDS supplements: to test or not to test? Ophthalmology 2015;122:212-5.
    • (2015) Ophthalmology , vol.122 , pp. 212-215
    • Chew, E.Y.1    Klein, M.L.2    Clemons, T.E.3    Agron, E.4    Abecasis, G.R.5
  • 151
    • 84962802885 scopus 로고    scopus 로고
    • Increased macular pigment optical density and visual acuity following consumption of a buttermilk drink containing lutein-enriched egg yolks: a randomized, double-blind, placebo-controlled trial
    • van der Made SM, Kelly ER, Kijlstra A, Plat J, Berendschot TTJM. Increased macular pigment optical density and visual acuity following consumption of a buttermilk drink containing lutein-enriched egg yolks: a randomized, double-blind, placebo-controlled trial. J Ophthalmol 2016;2016:9035745.
    • (2016) J Ophthalmol , vol.2016
    • van der Made, S.M.1    Kelly, E.R.2    Kijlstra, A.3    Plat, J.4    Berendschot, T.T.J.M.5
  • 152
    • 84868213899 scopus 로고    scopus 로고
    • Effect of lutein and zeaxanthin on macular pigment and visual function in patients with early age-related macular degeneration
    • Ma L, Yan SF, Huang YM, Lu XR, Qian F, Pang HL, Xu XR, Zou ZY, Dong PC, Xiao X, et al. Effect of lutein and zeaxanthin on macular pigment and visual function in patients with early age-related macular degeneration. Ophthalmology 2012;119:2290-7.
    • (2012) Ophthalmology , vol.119 , pp. 2290-2297
    • Ma, L.1    Yan, S.F.2    Huang, Y.M.3    Lu, X.R.4    Qian, F.5    Pang, H.L.6    Xu, X.R.7    Zou, Z.Y.8    Dong, P.C.9    Xiao, X.10
  • 153
    • 14144251629 scopus 로고    scopus 로고
    • Fasting plasma zeaxanthin response to Fructus barbarum L.(wolfberry; Kei Tze) in a food-based human supplementation trial
    • Cheng CY, Chung WY, Szeto YT, Benzie IF. Fasting plasma zeaxanthin response to Fructus barbarum L.(wolfberry; Kei Tze) in a food-based human supplementation trial. Br J Nutr 2005;93:123-30.
    • (2005) Br J Nutr , vol.93 , pp. 123-130
    • Cheng, C.Y.1    Chung, W.Y.2    Szeto, Y.T.3    Benzie, I.F.4
  • 155
    • 84863710321 scopus 로고    scopus 로고
    • Blueberry anthocyanins: protection against ageing and lightinduced damage in retinal pigment epithelial cells
    • Liu Y, Song X, Zhang D, Zhou F, Wang D, Wei Y, Gao F, Xie L, Jia G, Wu W. Blueberry anthocyanins: protection against ageing and lightinduced damage in retinal pigment epithelial cells. Br J Nutr 2012; 108:16-27.
    • (2012) Br J Nutr , vol.108 , pp. 16-27
    • Liu, Y.1    Song, X.2    Zhang, D.3    Zhou, F.4    Wang, D.5    Wei, Y.6    Gao, F.7    Xie, L.8    Jia, G.9    Wu, W.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.