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Volumn 30, Issue 1, 2018, Pages 1-16

Inflammation and depression: A causal or coincidental link to the pathophysiology?

Author keywords

anti inflammatory drugs; antidepressants; cytokines; inflammation; neurotoxins; prostaglandins

Indexed keywords

3 HYDROXYKYNURENINE; AGOMELATINE; AMFEBUTAMONE; ANTIDEPRESSANT AGENT; ARIPIPRAZOLE; ATOMOXETINE; CELECOXIB; CYCLOOXYGENASE 2 INHIBITOR; DESIPRAMINE; FLUVOXAMINE; IMIPRAMINE; INFLIXIMAB; MINOCYCLINE; NEUROTOXIN; NITRIC OXIDE SYNTHASE INHIBITOR; PROSTAGLANDIN; QUINOLINIC ACID; REBOXETINE;

EID: 85010905692     PISSN: 09242708     EISSN: 16015215     Source Type: Journal    
DOI: 10.1017/neu.2016.69     Document Type: Review
Times cited : (321)

References (129)
  • 1
    • 34347268434 scopus 로고    scopus 로고
    • Brainimmune communication pathways
    • QUAN N, BANKS WA. Brainimmune communication pathways. Brain Behav Immun 2007; 21: 727-735.
    • (2007) Brain Behav Immun , vol.21 , pp. 727-735
    • Quan, N.1    Banks, W.A.2
  • 4
    • 0035155254 scopus 로고    scopus 로고
    • Basic principles of immunological surveillance of the normal central nervous system
    • HICKEY WF. Basic principles of immunological surveillance of the normal central nervous system. Glia 2001; 36: 118-124.
    • (2001) Glia , vol.36 , pp. 118-124
    • Hickey, W.F.1
  • 6
    • 0028791506 scopus 로고
    • Lymphocyte adhesion, and transendothelial migration in the central nervous system: The role of LFA1, ICAM1, VLA4, and VCAM1 off
    • GREENWOOD J, WANG Y, CALDER VL. Lymphocyte adhesion, and transendothelial migration in the central nervous system: the role of LFA1, ICAM1, VLA4, and VCAM1. off. Immunology 1995; 86: 408-415.
    • (1995) Immunology , vol.86 , pp. 408-415
    • Greenwood, J.1    Wang, Y.2    Calder, V.L.3
  • 7
    • 33646072818 scopus 로고    scopus 로고
    • The P2 ? 7 receptor: A key player in IL1 processing, and release
    • FERRARI D, PIZZIRANI C, ADINOLFI E, et al. The P2 ? 7 receptor: a key player in IL1 processing, and release. Journal of Immunol 2006; 176(7): 3877-3883.
    • (2006) Journal of Immunol , vol.176 , Issue.7 , pp. 3877-3883
    • Ferrari, D.1    Pizzirani, C.2    Adinolfi, E.3
  • 8
    • 84878124765 scopus 로고    scopus 로고
    • The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses
    • IWATA M, OTA KT, DUMAN RS. The inflammasome: pathways linking psychological stress, depression, and systemic illnesses. Brain Behav Immun 2013; 31: 105-114.
    • (2013) Brain Behav Immun , vol.31 , pp. 105-114
    • Iwata, M.1    Ota, K.T.2    Duman, R.S.3
  • 9
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • NIMMERJAHN A, KIRCHHOFF F, HELMCHEN F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science 2005; 308: 1314-1318.
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 10
    • 77955090344 scopus 로고    scopus 로고
    • Tickets to the brain: Role of CCR2, and CX3CR1 in myeloid cell entry in the CNS
    • PRINZ M, PRILLER J. Tickets to the brain: role of CCR2, and CX3CR1 in myeloid cell entry in the CNS. J Neuroimmunol 2010; 224: 80-84.
    • (2010) J Neuroimmunol , vol.224 , pp. 80-84
    • Prinz, M.1    Priller, J.2
  • 11
    • 49549087762 scopus 로고    scopus 로고
    • Aging exacerbates depressivelike behavior in mice in response to activation of the peripheral innate immune system
    • GODBOUT JP, MOREAU M, LESTAGE J, et al. Aging exacerbates depressivelike behavior in mice in response to activation of the peripheral innate immune system. Neuropsychopharmacology 2008; 33: 2341-2351.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2341-2351
    • Godbout, J.P.1    Moreau, M.2    Lestage, J.3
  • 12
    • 78650994912 scopus 로고    scopus 로고
    • Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge
    • WYNNE AM, HENRY CJ, HUANG Y, CLELAND A, GODBOUT JP. Protracted downregulation of CX3CR1 on microglia of aged mice after lipopolysaccharide challenge. Brain Behav Immun 2010; 24: 1190-1201.
    • (2010) Brain Behav Immun , vol.24 , pp. 1190-1201
    • Wynne, A.M.1    Henry, C.J.2    Huang, Y.3    Cleland, A.4    Godbout, J.P.5
  • 13
    • 34548809845 scopus 로고    scopus 로고
    • Inflammation depression, and dementia: Are they connected?
    • LEONARD BE. Inflammation, depression, and dementia: are they connected? Neurochem Res 2007; 32: 1749-1756.
    • (2007) Neurochem Res , vol.32 , pp. 1749-1756
    • Leonard, B.E.1
  • 15
    • 6044238142 scopus 로고    scopus 로고
    • Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF
    • ROTHERMUNDT M, FALKAI P, PONATH G, et al. Glial cell dysfunction in schizophrenia indicated by increased S100B in the CSF. Mol Psychiatry 2004; 9: 897-899.
    • (2004) Mol Psychiatry , vol.9 , pp. 897-899
    • Rothermundt, M.1    Falkai, P.2    Ponath, G.3
  • 16
    • 0036273683 scopus 로고    scopus 로고
    • IL1 beta signalling in glial cells in wildtype, and IL1RI deficient mice
    • PARKER LC, LUHESHI GN, ROTHWELL NJ, PINTEAUX E. IL1 beta signalling in glial cells in wildtype, and IL1RI deficient mice. Br J Pharmacol 2002; 136: 312-320.
    • (2002) Br J Pharmacol , vol.136 , pp. 312-320
    • Parker, L.C.1    Luheshi, G.N.2    Rothwell, N.J.3    Pinteaux, E.4
  • 17
    • 0030804411 scopus 로고    scopus 로고
    • Evidence for an intramedullary prostaglandindependent mechanism in the activation of stressrelated neuroendocrine circuitry by intravenous interleukin1
    • ERICSSON A, ARIAS C, SAWCHENKO PE. Evidence for an intramedullary prostaglandindependent mechanism in the activation of stressrelated neuroendocrine circuitry by intravenous interleukin1. J Neurosci 1997; 17: 7166-7179.
    • (1997) J Neurosci , vol.17 , pp. 7166-7179
    • Ericsson, A.1    Arias, C.2    Sawchenko, P.E.3
  • 18
    • 0029074513 scopus 로고
    • Nitric oxide in the central nervous system
    • PAAKKARI I, LINDSBERG P. Nitric oxide in the central nervous system. Ann Med 1995; 27: 369-377.
    • (1995) Ann Med , vol.27 , pp. 369-377
    • Paakkari, I.1    Lindsberg, P.2
  • 19
    • 0035280252 scopus 로고    scopus 로고
    • Glucocorticoid receptors in major depression: Relevance to pathophysiology, and treatment
    • PARIANTE CM, MILLER AH. Glucocorticoid receptors in major depression: relevance to pathophysiology, and treatment. Biol Psychiatry 2001; 49: 391-404.
    • (2001) Biol Psychiatry , vol.49 , pp. 391-404
    • Pariante, C.M.1    Miller, A.H.2
  • 21
    • 0036904039 scopus 로고    scopus 로고
    • Cytokineinduced changes in mood, and behaviour: Implications for depression due to a general medical condition. Immunotherapy, and antidepressive treatment
    • POLLAK Y, YIRMIYA R. Cytokineinduced changes in mood, and behaviour: implications for ?depression due to a general medical condition. immunotherapy, and antidepressive treatment. Int J Neuropsychopharmacol 2002; 5: 389-399.
    • (2002) Int J Neuropsychopharmacol , vol.5 , pp. 389-399
    • Pollak, Y.1    Yirmiya, R.2
  • 22
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation, and the pathogenesis of depression
    • RAISON CL, CAPURON L, MILLER AH. Cytokines sing the blues: inflammation, and the pathogenesis of depression. Trends Immunol 2006; 27: 24-31.
    • (2006) Trends Immunol , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 23
    • 3042776968 scopus 로고    scopus 로고
    • Psychological stress, and the human immune system: A metaanalytic study of 30 years of inquiry
    • SEGERSTROM SC, MILLER GE. Psychological stress, and the human immune system: a metaanalytic study of 30 years of inquiry. Psychol Bull 2004; 130: 601-630.
    • (2004) Psychol Bull , vol.130 , pp. 601-630
    • Segerstrom, S.C.1    Miller, G.E.2
  • 24
    • 0037376354 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid resistance in splenocytes of socially stressed male mice
    • QUAN N, AVITSUR R, STARK JL, et al. Molecular mechanisms of glucocorticoid resistance in splenocytes of socially stressed male mice. J Neuroimmunol 2003; 137: 51-58.
    • (2003) J Neuroimmunol , vol.137 , pp. 51-58
    • Quan, N.1    Avitsur, R.2    Stark, J.L.3
  • 25
    • 70449376943 scopus 로고    scopus 로고
    • Cytokines, and glucocorticoid receptor signaling Relevance to major depression
    • PACE TW, MILLER AH. Cytokines, and glucocorticoid receptor signaling. Relevance to major depression. Ann NY Acad Sci 2009; 1179: 86-105.
    • (2009) Ann NY Acad Sci , vol.1179 , pp. 86-105
    • Pace, T.W.1    Miller, A.H.2
  • 26
    • 71549167579 scopus 로고    scopus 로고
    • Regulation of adult neurogenesis by stress, sleep disruption, exercise, and inflammation: Implications for depression, and antidepressant action
    • LUCASSEN PJ, MEERLO P, NAYLOR AS, et al. Regulation of adult neurogenesis by stress, sleep disruption, exercise, and inflammation: implications for depression, and antidepressant action. Eur Neuropsychopharmacol 2010; 20: 1-17.
    • (2010) Eur Neuropsychopharmacol , vol.20 , pp. 1-17
    • Lucassen, P.J.1    Meerlo, P.2    Naylor, A.S.3
  • 27
    • 84857046187 scopus 로고    scopus 로고
    • Interleukin 1beta: A new regulator of the kynurenine pathway affecting human hippocampal neurogenesis
    • ZUNSZAIN PA, ANACKER C, CATTANEO A, et al. Interleukin 1beta: a new regulator of the kynurenine pathway affecting human hippocampal neurogenesis. Neuropsychopharmacology 2012; 37: 939-949.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 939-949
    • Zunszain, P.A.1    Anacker, C.2    Cattaneo, A.3
  • 28
    • 45549084470 scopus 로고    scopus 로고
    • Brain interleukin1 mediates chronic stressinduced depression in mice via adrenocortical activation, and hippocampal neurogenesis suppression
    • GOSHEN I, KREISEL T, BENMENACHEMZIDON O, et al. Brain interleukin1 mediates chronic stressinduced depression in mice via adrenocortical activation, and hippocampal neurogenesis suppression. Mol Psychiatry 2008; 13: 717-728.
    • (2008) Mol Psychiatry , vol.13 , pp. 717-728
    • Goshen, I.1    Kreisel, T.2    Benmenachemzidon, O.3
  • 29
    • 0034063922 scopus 로고    scopus 로고
    • Social stress in laboratory rats: Hormonal responses, and immune cell distribution
    • STEFANSKI V. Social stress in laboratory rats: hormonal responses, and immune cell distribution. Psychoneuroendocrinology 2000; 25: 389-406.
    • (2000) Psychoneuroendocrinology , vol.25 , pp. 389-406
    • Stefanski, V.1
  • 30
    • 0035795076 scopus 로고    scopus 로고
    • Social stress increases the susceptibility to endotoxic shock
    • QUAN N, AVITSUR R, STARK JL, et al. Social stress increases the susceptibility to endotoxic shock. J Neuroimmunol 2001; 115: 36-45.
    • (2001) J Neuroimmunol , vol.115 , pp. 36-45
    • Quan, N.1    Avitsur, R.2    Stark, J.L.3
  • 31
    • 0034257924 scopus 로고    scopus 로고
    • Induction of IkappaBalpha mRNA expression in the brain by glucocorticoids: A negative feedback mechanism for immunetobrain signaling
    • QUAN N, HE L, LAI W, SHEN T, HERKENHAM M. Induction of IkappaBalpha mRNA expression in the brain by glucocorticoids: a negative feedback mechanism for immunetobrain signaling. J Neurosci 2000; 20: 6473-6477.
    • (2000) J Neurosci , vol.20 , pp. 6473-6477
    • Quan, N.1    Le, H.2    Lai, W.3    Shen, T.4    Herkenham, M.5
  • 32
    • 0032467785 scopus 로고    scopus 로고
    • Brain corticosteroid receptor balance in health, and disease
    • DE KLOET ER, VREUGDENHIL E, OITZL MS, JOELS M. Brain corticosteroid receptor balance in health, and disease. Endocr Rev 1998; 19: 269-301.
    • (1998) Endocr Rev , vol.19 , pp. 269-301
    • De Kloet, E.R.1    Vreugdenhil, E.2    Oitzl, M.S.3    Joels, M.4
  • 33
    • 34247880267 scopus 로고    scopus 로고
    • Stress induced morphological microglial activation in the rodent brain: Involvement of interleukin18
    • SUGAMA S, FUJITA M, HASHIMOTO M, CONTI B. Stress induced morphological microglial activation in the rodent brain: involvement of interleukin18. Neuroscience 2007; 146: 1388-1399.
    • (2007) Neuroscience , vol.146 , pp. 1388-1399
    • Sugama, S.1    Fujita, M.2    Hashimoto, M.3    Conti, B.4
  • 34
    • 35848950202 scopus 로고    scopus 로고
    • Immunological aspects in the neurobiology of suicide: Elevated microglial density in schizophrenia, and depression is associated with suicide
    • STEINER J, BIELAU H, BRISCH R, et al. Immunological aspects in the neurobiology of suicide: elevated microglial density in schizophrenia, and depression is associated with suicide. J Psychiatr Res 2008; 42: 151-157.
    • (2008) J Psychiatr Res , vol.42 , pp. 151-157
    • Steiner, J.1    Bielau, H.2    Brisch, R.3
  • 35
    • 0141864567 scopus 로고    scopus 로고
    • Mild depressive symptoms are associated with amplified, and prolonged inflammatory responses after influenza virus vaccination in older adults
    • GLASER R, ROBLES TF, SHERIDAN J, MALARKEY WB, KIECOLTGLASER JK. Mild depressive symptoms are associated with amplified, and prolonged inflammatory responses after influenza virus vaccination in older adults. Arch Gen Psychiatry 2003; 60: 1009-1014.
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 1009-1014
    • Glaser, R.1    Robles, T.F.2    Sheridan, J.3    Malarkey, W.B.4    Kiecoltglaser, J.K.5
  • 36
    • 0032573166 scopus 로고    scopus 로고
    • Glial reduction in the subgenual prefrontal cortex in mood disorders
    • ONGUR D, DREVETS WC, PRICE JL. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci USA 1998; 95: 13290-13295.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13290-13295
    • Ongur, D.1    Drevets, W.C.2    Price, J.L.3
  • 37
    • 84880847583 scopus 로고    scopus 로고
    • Inflammation, neurotoxins, and psychiatric disorders
    • MYINT AM. Inflammation, neurotoxins, and psychiatric disorders. Mod Trends Pharmacopsychiatri 2013; 28: 61-74.
    • (2013) Mod Trends Pharmacopsychiatri , vol.28 , pp. 61-74
    • Myint, A.M.1
  • 39
    • 80054699375 scopus 로고    scopus 로고
    • Cortisol exerts biphasic regulation of inflammation in humans
    • YEAGER MP, PIOLI PA, GUYRE PM. Cortisol exerts biphasic regulation of inflammation in humans. Dose Response 2011; 9: 332-347.
    • (2011) Dose Response , vol.9 , pp. 332-347
    • Yeager, M.P.1    Pioli, P.A.2    Guyre, P.M.3
  • 40
    • 0842263900 scopus 로고    scopus 로고
    • Glucocorticoid pretreatment induces cytokine overexpression, and nuclear factorkappaB activation in macrophages
    • SMYTH GP, STAPLETON PP, FREEMAN TA, et al. Glucocorticoid pretreatment induces cytokine overexpression, and nuclear factorkappaB activation in macrophages. J Surg Res 2004; 116: 253-261.
    • (2004) J Surg Res , vol.116 , pp. 253-261
    • Smyth, G.P.1    Stapleton, P.P.2    Freeman, T.A.3
  • 41
    • 0031282469 scopus 로고    scopus 로고
    • Increased serum IL6, and IL1 receptor antagonist concentrations in major depression, and treatment resistant depression
    • MAES M, BOSMANS E, DE JONGH R, KENIS G, VANDOOLAEGHE E, NEELS H. Increased serum IL6, and IL1 receptor antagonist concentrations in major depression, and treatment resistant depression. Cytokine 1997; 9: 853-858.
    • (1997) Cytokine , vol.9 , pp. 853-858
    • Maes, M.1    Bosmans, E.2    De Jongh, R.3    Kenis, G.4    Vandoolaeghe, E.5    Neels, H.6
  • 42
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurodegenerative (I& ND) hypothesis of depression: Leads for future research, and new drug developments in depression
    • MAES M, YIRMYIA R, NORABERG J, et al. The inflammatory & neurodegenerative (I& ND) hypothesis of depression: leads for future research, and new drug developments in depression. Metab Brain Dis 2009; 24: 27-53.
    • (2009) Metab Brain Dis , vol.24 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3
  • 44
    • 0242720163 scopus 로고    scopus 로고
    • Cytokineserotonin interaction through IDO: A neurodegeneration hypothesis of depression
    • MYINT AM, KIM YK. Cytokineserotonin interaction through IDO: a neurodegeneration hypothesis of depression. Med Hypotheses 2003; 61: 519-525.
    • (2003) Med Hypotheses , vol.61 , pp. 519-525
    • Myint, A.M.1    Kim, Y.K.2
  • 46
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • HART BL. Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 1988; 12: 123-137.
    • (1988) Neurosci Biobehav Rev , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 47
    • 84878155936 scopus 로고    scopus 로고
    • Malaise, melancholia, and madness: The evolutionary legacy of an inflammatory bias
    • RAISON CL, MILLER AH. Malaise, melancholia, and madness: the evolutionary legacy of an inflammatory bias. Brain Behav Immun 2013; 31: 1-8.
    • (2013) Brain Behav Immun , vol.31 , pp. 1-8
    • Raison, C.L.1    Miller, A.H.2
  • 48
    • 33846683003 scopus 로고    scopus 로고
    • Infectioninduced proinflammatory cytokines are associated with decreases in positive affect, but not increases in negative affect
    • JANICKIDEVERTS D, COHEN S, DOYLE WJ, TURNER RB, TREANOR JJ. Infectioninduced proinflammatory cytokines are associated with decreases in positive affect, but not increases in negative affect. Brain Behav Immun 2007; 21: 301-307.
    • (2007) Brain Behav Immun , vol.21 , pp. 301-307
    • Janickideverts, D.1    Cohen, S.2    Doyle, W.J.3    Turner, R.B.4    Treanor, J.J.5
  • 49
    • 0035088327 scopus 로고    scopus 로고
    • Effects of antidepressant drugs on the behavioral, and physiological responses to lipopolysaccharide (LPS) in rodents
    • YIRMIYA R, POLLAK Y, BARAK O, et al. Effects of antidepressant drugs on the behavioral, and physiological responses to lipopolysaccharide (LPS) in rodents. Neuropsychopharmacology 2001; 24: 531-544.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 531-544
    • Yirmiya, R.1    Pollak, Y.2    Barak, O.3
  • 50
    • 0036901920 scopus 로고    scopus 로고
    • Effects of antidepressants on the production of cytokines
    • KENIS G, MAES M. Effects of antidepressants on the production of cytokines. Int J Neuropsychopharmacol 2002; 5: 401-412.
    • (2002) Int J Neuropsychopharmacol , vol.5 , pp. 401-412
    • Kenis, G.1    Maes, M.2
  • 51
    • 0033512181 scopus 로고    scopus 로고
    • Fluoxetine, and amitriptyline inhibit nitric oxide, prostaglandin E2, and hyaluronic acid production in human synovial cells, and synovial tissue cultures
    • YARON I, SHIRAZI I, JUDOVICH R, LEVARTOVSKY D, CASPI D, YARON M. Fluoxetine, and amitriptyline inhibit nitric oxide, prostaglandin E2, and hyaluronic acid production in human synovial cells, and synovial tissue cultures. Arthritis Rheum 1999; 42: 2561-2568.
    • (1999) Arthritis Rheum , vol.42 , pp. 2561-2568
    • Yaron, I.1    Shirazi, I.2    Judovich, R.3    Levartovsky, D.4    Caspi, D.5    Yaron, M.6
  • 52
    • 19944391381 scopus 로고    scopus 로고
    • The olfactory bulbectomised rat as a model of depression
    • SONG C, LEONARD BE. The olfactory bulbectomised rat as a model of depression. Neurosci Biobehav Rev 2005; 29: 627-647.
    • (2005) Neurosci Biobehav Rev , vol.29 , pp. 627-647
    • Song, C.1    Leonard, B.E.2
  • 53
    • 35649019844 scopus 로고    scopus 로고
    • Role of paroxetine in interferonalphainduced immune, and behavioural changes in male Wistar rats
    • MYINT AM, O?MAHONY S, KUBERA M, et al. Role of paroxetine in interferonalphainduced immune, and behavioural changes in male Wistar rats. J Psychopharmacol 2007; 21: 843-850.
    • (2007) J Psychopharmacol , vol.21 , pp. 843-850
    • Myint, A.M.1    O'mahony, S.2    Kubera, M.3
  • 54
    • 79958766746 scopus 로고    scopus 로고
    • Effects of eicosapentaenoic acid, and fluoxetine on plasma cortisol, serum interleukin1beta, and interleukin6 concentrations in patients with major depressive disorder
    • JAZAYERI S, KESHAVARZ SA, TEHRANIDOOST M, et al. Effects of eicosapentaenoic acid, and fluoxetine on plasma cortisol, serum interleukin1beta, and interleukin6 concentrations in patients with major depressive disorder. Psychiatry Res 2010; 178: 112-115.
    • (2010) Psychiatry Res , vol.178 , pp. 112-115
    • Jazayeri, S.1    Keshavarz, S.A.2    Tehranidoost, M.3
  • 55
    • 0029146932 scopus 로고
    • Increased plasma concentrations of interleukin6, soluble interleukin6, soluble interleukin2, and transferrin receptor in major depression
    • MAES M, MELTZER HY, BOSMANS E, et al. Increased plasma concentrations of interleukin6, soluble interleukin6, soluble interleukin2, and transferrin receptor in major depression. J Affect Disord 1995; 34: 301-309.
    • (1995) J Affect Disord , vol.34 , pp. 301-309
    • Maes, M.1    Meltzer, H.Y.2    Bosmans, E.3
  • 56
    • 33845362024 scopus 로고    scopus 로고
    • Chronic fluoxetine increases cytosolic phospholipase A 2) activity, and arachidonic acid turnover in brain phospholipids of the unanesthetized rat
    • LEE HJ, RAO JS, ERTLEY RN, CHANG L, RAPOPORT SI, BAZINET RP. Chronic fluoxetine increases cytosolic phospholipase A(2) activity, and arachidonic acid turnover in brain phospholipids of the unanesthetized rat. Psychopharmacology 2007; 190: 103-115.
    • (2007) Psychopharmacology , Issue.190 , pp. 103-115
    • Lee, H.J.1    Rao, J.S.2    Ertley, R.N.3    Chang, L.4    Rapoport, S.I.5    Bazinet, R.P.6
  • 57
    • 42049086339 scopus 로고    scopus 로고
    • History of depression, depressive symptoms, and medial temporal lobe atrophy, and the risk of Alzheimer disease
    • GEERLINGS MI, DEN HEIJER T, KOUDSTAAL PJ, HOFMAN A, BRETELER MM. History of depression, depressive symptoms, and medial temporal lobe atrophy, and the risk of Alzheimer disease. Neurology 2008; 70: 1258-1264.
    • (2008) Neurology , vol.70 , pp. 1258-1264
    • Geerlings, M.I.1    Den Heijer, T.2    Koudstaal, P.J.3    Hofman, A.4    Breteler, M.M.5
  • 58
    • 0035670095 scopus 로고    scopus 로고
    • History of depression as a risk factor for dementia: An updated review
    • JORM AF. History of depression as a risk factor for dementia: an updated review. Aust NZ J Psychiatry 2001; 35: 776-781.
    • (2001) Aust NZ J Psychiatry , vol.35 , pp. 776-781
    • Jorm, A.F.1
  • 59
    • 32244440323 scopus 로고    scopus 로고
    • Increased hippocampal plaques, and tangles in patients with Alzheimer disease with a lifetime history of major depression
    • RAPP MA, SCHNAIDERBEERI M, GROSSMAN HT, et al. Increased hippocampal plaques, and tangles in patients with Alzheimer disease with a lifetime history of major depression. Arch Gen Psychiatry 2006; 63: 161-167.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 161-167
    • Rapp, M.A.1    Schnaiderbeeri, M.2    Grossman, H.T.3
  • 60
    • 43149101276 scopus 로고    scopus 로고
    • Amyloidassociated depression: A prodromal depression of Alzheimer disease?
    • SUN X, STEFFENS DC, AU R, et al. Amyloidassociated depression: a prodromal depression of Alzheimer disease? Arch Gen Psychiatry 2008; 65: 542-550.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 542-550
    • Sun, X.1    Steffens, D.C.2
  • 61
    • 0035030335 scopus 로고    scopus 로고
    • Changes in the immune system in depression, and dementia causal or coincidental effects?
    • LEONARD BE. Changes in the immune system in depression, and dementia: causal or coincidental effects? Int J Dev Neurosci 2001; 19: 305-312.
    • (2001) Int J Dev Neurosci , vol.19 , pp. 305-312
    • Leonard, B.E.1
  • 62
    • 33746328671 scopus 로고    scopus 로고
    • Changes in the immune system in depression, and dementia: Causal or coincidental effects?
    • LEONARD BE, MYINT A. Changes in the immune system in depression, and dementia: causal or coincidental effects? Dialogues Clin Neurosci 2006; 8: 163-174.
    • (2006) Dialogues Clin Neurosci , vol.8 , pp. 163-174
    • Leonard, B.E.1    Myint, A.2
  • 63
    • 0014682651 scopus 로고
    • Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect
    • LAPIN IP, OXENKRUG GF. Intensification of the central serotoninergic processes as a possible determinant of the thymoleptic effect. Lancet 1969; 1: 132-136.
    • (1969) Lancet , vol.1 , pp. 132-136
    • Lapin, I.P.1    Oxenkrug, G.F.2
  • 64
    • 0015734617 scopus 로고
    • Kynurenines as probable participants of depression
    • LAPIN IP. Kynurenines as probable participants of depression. Pharmakopsychiatr NeuroPsychopharmakol 1973; 6: 273-279.
    • (1973) Pharmakopsychiatr NeuroPsychopharmakol , vol.6 , pp. 273-279
    • Lapin, I.P.1
  • 65
    • 0019223613 scopus 로고
    • Dietary tryptophan level, and the enzymes of tryptophan NAD pathway
    • SATYANARAYANA U, RAO BS. Dietary tryptophan level, and the enzymes of tryptophan NAD pathway. Br J Nutr 1980; 43: 107-113.
    • (1980) Br J Nutr , vol.43 , pp. 107-113
    • Satyanarayana, U.1    Rao, B.S.2
  • 66
    • 0024595719 scopus 로고
    • Interferoninduced indoleamine 2, 3dioxygenase activity in human mononuclear phagocytes
    • CARLIN JM, BORDEN EC, SONDEL PM, BYRNE GI. Interferoninduced indoleamine 2, 3dioxygenase activity in human mononuclear phagocytes. J Leukoc Biol 1989; 45: 29-34.
    • (1989) J Leukoc Biol , vol.45 , pp. 29-34
    • Carlin, J.M.1    Borden, E.C.2    Sondel, P.M.3    Byrne, G.I.4
  • 67
    • 0025944659 scopus 로고
    • Relationship between interferongamma, indoleamine 2, 3dioxygenase, and tryptophan catabolism
    • TAYLOR MW, FENG GS. Relationship between interferongamma, indoleamine 2, 3dioxygenase, and tryptophan catabolism. FASEB J 1991; 5: 2516-2522.
    • (1991) FASEB J , vol.5 , pp. 2516-2522
    • Taylor, M.W.1    Feng, G.S.2
  • 68
    • 0018901290 scopus 로고
    • Lkynurenine: Its syn thesis and possible regulatory function in brain
    • GAL EM, SHERMAN AD. Lkynurenine: its synthesis, and possible regulatory function in brain. Neurochem Res 1980; 5: 223-239.
    • (1980) Neurochem Res , vol.5 , pp. 223-239
    • Gal, E.M.1    Sherman, A.D.2
  • 69
    • 0019967973 scopus 로고
    • An iontophoretic investigation of the actions of convulsant kynurenines, and their interaction with the endogenous excitant quinolinic acid
    • PERKINS MN, STONE TW. An iontophoretic investigation of the actions of convulsant kynurenines, and their interaction with the endogenous excitant quinolinic acid. Brain Res 1982; 247: 184-187.
    • (1982) Brain Res , vol.247 , pp. 184-187
    • Perkins, M.N.1    Stone, T.W.2
  • 70
    • 0031930117 scopus 로고    scopus 로고
    • Murine glial cells regenerate NAD, after peroxideinduced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates
    • GRANT RS, KAPOOR V. Murine glial cells regenerate NAD, after peroxideinduced depletion, using either nicotinic acid, nicotinamide, or quinolinic acid as substrates. J Neurochem 1998; 70: 1759-1763.
    • (1998) J Neurochem , vol.70 , pp. 1759-1763
    • Grant, R.S.1    Kapoor, V.2
  • 71
    • 11144314849 scopus 로고    scopus 로고
    • Expression of indoleamine 2, 3dioxygenase, and production of quinolinic acid by human microglia, astrocytes, and neurons
    • GUILLEMIN GJ, SMYTHE G, TAKIKAWA O, BREW BJ. Expression of indoleamine 2, 3dioxygenase, and production of quinolinic acid by human microglia, astrocytes, and neurons. Glia 2005; 49: 15-23.
    • (2005) Glia , vol.49 , pp. 15-23
    • Guillemin, G.J.1    Smythe, G.2    Takikawa, O.3    Brew, B.J.4
  • 72
    • 0033928598 scopus 로고    scopus 로고
    • Characterisation of kynurenine pathway metabolism in human astrocytes, and implications in neuropathogenesis
    • GUILLEMIN GJ, SMITH DG, KERR SJ, et al. Characterisation of kynurenine pathway metabolism in human astrocytes, and implications in neuropathogenesis. Redox Rep 2000; 5: 108-111.
    • (2000) Redox Rep , vol.5 , pp. 108-111
    • Guillemin, G.J.1    Smith, D.G.2    Kerr, S.J.3
  • 73
    • 27344457006 scopus 로고    scopus 로고
    • Quinolinic acid selectively induces apoptosis of human astrocytes: Potential role in AIDS dementia complex
    • GUILLEMIN GJ, WANG L, BREW BJ. Quinolinic acid selectively induces apoptosis of human astrocytes: potential role in AIDS dementia complex. J Neuroinflammation 2005; 2: 16.
    • (2005) J Neuroinflammation , vol.2 , pp. 16
    • Guillemin, G.J.1    Wang, L.2    Brew, B.J.3
  • 76
    • 81155157520 scopus 로고    scopus 로고
    • Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus evidence for an immunemodulated glutamatergic neurotransmission?
    • STEINER J, WALTER M, GOS T, et al. Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immunemodulated glutamatergic neurotransmission? J Neuroinflammation 2011; 8: 94.
    • (2011) J Neuroinflammation , vol.8 , pp. 94
    • Steiner, J.1    Walter, M.2    Gos, T.3
  • 77
    • 84857625633 scopus 로고    scopus 로고
    • The role of the kynurenine metabolism in major depression
    • MYINT AM, SCHWARZ MJ, MULLER N. The role of the kynurenine metabolism in major depression. J Neural Transm 2012; 119: 245-251.
    • (2012) J Neural Transm , vol.119 , pp. 245-251
    • Myint, A.M.1    Schwarz, M.J.2    Muller, N.3
  • 78
    • 75849150001 scopus 로고    scopus 로고
    • Structure, expression, and function of kynurenine aminotransferases in human, and rodent brains
    • HAN Q, CAI T, TAGLE DA, LI J. Structure, expression, and function of kynurenine aminotransferases in human, and rodent brains. Cell Mol Life Sci 2010; 67: 353-368.
    • (2010) Cell Mol Life Sci , vol.67 , pp. 353-368
    • Han, Q.1    Cai, T.2    Tagle, D.A.3    Li, J.4
  • 79
    • 84885321044 scopus 로고    scopus 로고
    • Insulin resistance, and dysregulation of tryptophankynurenine, and kynureninenicotinamide adenine dinucleotide metabolic pathways
    • OXENKRUG G. Insulin resistance, and dysregulation of tryptophankynurenine, and kynureninenicotinamide adenine dinucleotide metabolic pathways. Mol Neurobiol 2013; 48: 294-301.
    • (2013) Mol Neurobiol , vol.48 , pp. 294-301
    • Oxenkrug, G.1
  • 80
    • 84897954401 scopus 로고    scopus 로고
    • CSF, and brain indices of insulin resistance, oxidative stress, and neuroinflammation in early versus late Alzheimer?s disease
    • LEE S, TONG M, HANG S, DEOCHAND C, DE LA MONTE S. CSF, and brain indices of insulin resistance, oxidative stress, and neuroinflammation in early versus late Alzheimer?s disease. J Alzheimers Dis Parkinsonism 2013; 3: 128.
    • (2013) J Alzheimers Dis Parkinsonism , vol.3 , pp. 128
    • Lee, S.1    Tong, M.2    Hang, S.3    Deochand, C.4    De, L.A.5    Monte, S.6
  • 81
    • 34249788738 scopus 로고    scopus 로고
    • Mitochondria, metabolic disturbances, oxidative stress, and the kynurenine system, with focus on neurodegenerative disorders
    • SAS K, ROBOTKA H, TOLDI J, VECSEI L. Mitochondria, metabolic disturbances, oxidative stress, and the kynurenine system, with focus on neurodegenerative disorders. J Neurol Sci 2007; 257: 221-239.
    • (2007) J Neurol Sci , vol.257 , pp. 221-239
    • Sas, K.1    Robotka, H.2    Toldi, J.3    Vecsei, L.4
  • 82
    • 85041779010 scopus 로고
    • Bloom FE editor. Psychopharmacology the 3rd generation of progress. NY: Raven Press
    • MAES M, MELTZER HY. The serotonin hypothesis of major depression. In: Bloom FE, editor. Psychopharmacology the 3rd generation of progress. NY: Raven Press, 1995; p. 946-993.
    • (1995) The Serotonin Hypothesis of Major Depression , pp. 946-993
    • Maes, M.1    Meltzer, H.Y.2
  • 83
    • 0036288309 scopus 로고    scopus 로고
    • The neuropharmacology of serotonin, and noradrenaline in depression
    • NUTT DJ. The neuropharmacology of serotonin, and noradrenaline in depression. International Clinical Psychopharmacology 2002; 17(Suppl. 1): S1-S12.
    • (2002) International Clinical Psychopharmacology , vol.17 , pp. S1-S12
    • Nutt, D.J.1
  • 85
    • 12944281042 scopus 로고    scopus 로고
    • Pronounced, and sustained central hypernoradrenergic function in major depression with melancholic features: Relation to hypercortisolism, and corticotropinreleasing hormone
    • WONG ML, KLING MA, MUNSON PJ, et al. Pronounced, and sustained central hypernoradrenergic function in major depression with melancholic features: relation to hypercortisolism, and corticotropinreleasing hormone. Proc Natl Acad Sci USA 2000; 97: 325-330.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 325-330
    • Wong, M.L.1    Kling, M.A.2    Munson, P.J.3
  • 86
    • 0035034203 scopus 로고    scopus 로고
    • The cellular neurobiology of depression
    • MANJI HK, DREVETS WC, CHARNEY DS. The cellular neurobiology of depression. Nat Med 2001; 7: 541-547.
    • (2001) Nat Med , vol.7 , pp. 541-547
    • Manji, H.K.1    Drevets, W.C.2    Charney, D.S.3
  • 87
    • 27744485503 scopus 로고    scopus 로고
    • Antidepressant action: To the nucleus, and beyond
    • MALBERG JE, BLENDY JA. Antidepressant action: to the nucleus, and beyond. Trends Pharmacol Sci 2005; 26: 631-638.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 631-638
    • Malberg, J.E.1    Blendy, J.A.2
  • 88
    • 33750061011 scopus 로고    scopus 로고
    • Phosphodiesterase genes are associated with susceptibility to major depression, and antidepressant treatment response
    • WONG ML, WHELAN F, DELOUKAS P, et al. Phosphodiesterase genes are associated with susceptibility to major depression, and antidepressant treatment response. Proc Natl Acad Sci USA 2006; 103: 15124-15129.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 15124-15129
    • Wong, M.L.1    Whelan, F.2    Deloukas, P.3
  • 90
    • 0033057940 scopus 로고    scopus 로고
    • Negative immunoregulatory effects of antidepressants: Inhibition of interferongamma, and stimulation of interleukin10 secretion
    • MAES M, SONG C, LIN AH, et al. Negative immunoregulatory effects of antidepressants: inhibition of interferongamma, and stimulation of interleukin10 secretion. Neuropsychopharmacology 1999; 20: 370-379.
    • (1999) Neuropsychopharmacology , vol.20 , pp. 370-379
    • Maes, M.1    Song, C.2    Lin, A.H.3
  • 91
    • 0030220185 scopus 로고    scopus 로고
    • Tricyclic antidepressants inhibit IL6, IL1 beta, and TNFalpha release in human blood monocytes, and IL2, and interferongamma in T cells
    • XIA Z, DEPIERRE JW, NASSBERGER L. Tricyclic antidepressants inhibit IL6, IL1 beta, and TNFalpha release in human blood monocytes, and IL2, and interferongamma in T cells. Immunopharmacology 1996; 34: 27-37.
    • (1996) Immunopharmacology , vol.34 , pp. 27-37
    • Xia, Z.1    Depierre, J.W.2    Nassberger, L.3
  • 92
    • 34250648917 scopus 로고    scopus 로고
    • Antidepressants inhibit interferongammainduced microglial production of IL6, and nitric oxide
    • HASHIOKA S, KLEGERIS A, MONJI A, et al. Antidepressants inhibit interferongammainduced microglial production of IL6, and nitric oxide. Exp Neurol 2007; 206: 33-42.
    • (2007) Exp Neurol , vol.206 , pp. 33-42
    • Hashioka, S.1    Klegeris, A.2    Monji, A.3
  • 93
    • 4444275473 scopus 로고    scopus 로고
    • Therapeutic monitoring of psychotropic drugs: An outline of the AGNPTDM expert group consensus guideline
    • BAUMANN P, HIEMKE C, ULRICH S, et al. Therapeutic monitoring of psychotropic drugs: an outline of the AGNPTDM expert group consensus guideline. Ther Drug Monit 2004; 26: 167-170.
    • (2004) Ther Drug Monit , vol.26 , pp. 167-170
    • Baumann, P.1    Hiemke, C.2    Ulrich, S.3
  • 94
    • 42449095441 scopus 로고    scopus 로고
    • Neurotransmitter, peptide, and cytokine processes in relation to depressive disorder: Comorbidity between depression, and neurodegenerative disorders
    • ANISMAN H, MERALI Z, HAYLEY S. Neurotransmitter, peptide, and cytokine processes in relation to depressive disorder: comorbidity between depression, and neurodegenerative disorders. Prog Neurobiol 2008; 85: 1-74.
    • (2008) Prog Neurobiol , vol.85 , pp. 1-74
    • Anisman, H.1    Merali, Z.2    Hayley, S.3
  • 95
    • 0032988919 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors have antidepressantlike properties in mice 1 Acute treatments are active in the forced swim test
    • HARKIN AJ, BRUCE KH, CRAFT B, PAUL IA. Nitric oxide synthase inhibitors have antidepressantlike properties in mice. 1. Acute treatments are active in the forced swim test. Eur J Pharmacol 1999; 372: 207-213.
    • (1999) Eur J Pharmacol , Issue.372 , pp. 207-213
    • Harkin, A.J.1    Bruce, K.H.2    Craft, B.3    Paul, I.A.4
  • 96
    • 0038147541 scopus 로고    scopus 로고
    • Enhancing neuronal plasticity, and cellular resilience to develop novel, improved therapeutics for difficulttotreat depression
    • MANJI HK, QUIROZ JA, SPORN J, et al. Enhancing neuronal plasticity, and cellular resilience to develop novel, improved therapeutics for difficulttotreat depression. Biol Psychiatry 2003; 53: 707-742.
    • (2003) Biol Psychiatry , vol.53 , pp. 707-742
    • Manji, H.K.1    Quiroz, J.A.2    Sporn, J.3
  • 97
    • 84880284024 scopus 로고    scopus 로고
    • Nitric oxide signaling in depression, and antidepressant action
    • In LopezMunoz F, Alamo C, editors. Boca Raton CRC Press
    • WEGENER G, MATHÉ AA. Nitric oxide signaling in depression, and antidepressant action. In: LopezMunoz F, Alamo C, editors. Neurobiology of depression. Frontiers in neuroscience. Boca Raton: CRC Press, 2012; p. 341-370.
    • (2012) Neurobiology of Depression. Frontiers in Neuroscience , pp. 341-370
    • Wegener, G.1    Mathé, A.A.2
  • 98
    • 77951958758 scopus 로고    scopus 로고
    • Nitric oxide synthase inhibitors as antidepressants
    • WEGENER G, VOLKE V. Nitric oxide synthase inhibitors as antidepressants. Pharmaceuticals 2010; 3: 273-299.
    • (2010) Pharmaceuticals , vol.3 , pp. 273-299
    • Wegener, G.1    Volke, V.2
  • 99
    • 33745617042 scopus 로고    scopus 로고
    • The cyclooxygenase2 inhibitor celecoxib has therapeutic effects in major depression: Results of a doubleblind, randomized, placebo controlled, addon pilot study to reboxetine
    • MULLER N. The cyclooxygenase2 inhibitor celecoxib has therapeutic effects in major depression: results of a doubleblind, randomized, placebo controlled, addon pilot study to reboxetine. Mol Psychiatry 2006; 11: 680-684.
    • (2006) Mol Psychiatry , vol.11 , pp. 680-684
    • Muller, N.1
  • 101
    • 33645103130 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressantlike effects
    • JOCA SR, GUIMARAES FS. Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressantlike effects. Psychopharmacology 2006; 185: 298-305.
    • (2006) Psychopharmacology , vol.185 , pp. 298-305
    • Joca, S.R.1    Guimaraes, F.S.2
  • 102
    • 0037151298 scopus 로고    scopus 로고
    • Reduction of cGMP, and nitric oxide has antidepressantlike effects in the forced swimming test in rats
    • HEIBERG IL, WEGENER G, ROSENBERG R. Reduction of cGMP, and nitric oxide has antidepressantlike effects in the forced swimming test in rats. Behav Brain Res 2002; 134: 479-484.
    • (2002) Behav Brain Res , vol.134 , pp. 479-484
    • Heiberg, I.L.1    Wegener, G.2    Rosenberg, R.3
  • 103
    • 0344520448 scopus 로고    scopus 로고
    • Antidepressant, and anxiolyticlike effects of selective neuronal NOS inhibitor 1(2trifluoromethylphenyl) imidazole in mice
    • VOLKE V, WEGENER G, BOURIN M, VASAR E. Antidepressant, and anxiolyticlike effects of selective neuronal NOS inhibitor 1(2trifluoromethylphenyl) imidazole in mice. Behav Brain Res 2003; 140: 141-147.
    • (2003) Behav Brain Res , vol.140 , pp. 141-147
    • Volke, V.1    Wegener, G.2    Bourin, M.3    Vasar, E.4
  • 104
    • 0037382381 scopus 로고    scopus 로고
    • Serotonergic mediation of the antidepressantlike effects of nitric oxide synthase inhibitors
    • HARKIN A, CONNOR TJ, WALSH M, ST JOHN N, KELLY JP. Serotonergic mediation of the antidepressantlike effects of nitric oxide synthase inhibitors. Neuropharmacology 2003; 44: 616-623.
    • (2003) Neuropharmacology , vol.44 , pp. 616-623
    • Harkin, A.1    Connor, T.J.2    Walsh, M.3    John N, S.T.4    Kelly, J.P.5
  • 105
    • 77956421517 scopus 로고    scopus 로고
    • Inhibitory effects of SSRIs on IFNgamma induced microglial activation through the regulation of intracellular calcium
    • HORIKAWA H, KATO TA, MIZOGUCHI Y, et al. Inhibitory effects of SSRIs on IFNgamma induced microglial activation through the regulation of intracellular calcium. Prog Neuropsychopharmacol Biol Psychiatry 2010; 34: 1306-1316.
    • (2010) Prog Neuropsychopharmacol Biol Psychiatry , vol.34 , pp. 1306-1316
    • Horikawa, H.1    Kato, T.A.2    Mizoguchi, Y.3
  • 106
    • 69749086682 scopus 로고    scopus 로고
    • Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: Implications for depression, and neurodegeneration
    • O?SULLIVAN JB, RYAN KM, CURTIN NM, HARKIN A, CONNOR TJ. Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression, and neurodegeneration. Int J Neuropsychopharmacol 2009; 12: 687-699.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 687-699
    • O'sullivan, J.B.1    Ryan, K.M.2    Curtin, N.M.3    Harkin, A.4    Connor, T.J.5
  • 108
    • 51649096464 scopus 로고    scopus 로고
    • Inhibitory effects of aripiprazole on interferongammainduced microglial activation via intracellular Ca2 + regulation in vitro
    • KATO T, MIZOGUCHI Y, MONJI A, et al. Inhibitory effects of aripiprazole on interferongammainduced microglial activation via intracellular Ca2 + regulation in vitro. J Neurochem 2008; 106: 815-825.
    • (2008) J Neurochem , vol.106 , pp. 815-825
    • Kato, T.1    Mizoguchi, Y.2    Monji, A.3
  • 109
    • 33344465869 scopus 로고    scopus 로고
    • ProstacyclinIP signaling, and prostaglandin E2EP2/EP4 signaling both mediate joint inflammation in mouse collageninduced arthritis
    • HONDA T, SEGINISHIDA E, MIYACHI Y, NARUMIYA S. ProstacyclinIP signaling, and prostaglandin E2EP2/EP4 signaling both mediate joint inflammation in mouse collageninduced arthritis. J Exp Med 2006; 203: 325-335.
    • (2006) J Exp Med , vol.203 , pp. 325-335
    • Honda, T.1    Seginishida, E.2    Miyachi, Y.3    Narumiya, S.4
  • 110
    • 79958134859 scopus 로고    scopus 로고
    • Prostanoids, and inflammation: A new concept arising from receptor knockout mice
    • NARUMIYA S. Prostanoids, and inflammation: a new concept arising from receptor knockout mice. J Mol Med 2009; 87: 1015-1022.
    • (2009) J Mol Med , vol.87 , pp. 1015-1022
    • Narumiya, S.1
  • 111
    • 84861875788 scopus 로고    scopus 로고
    • Prostaglandins, and chronic inflammation
    • AOKI T, NARUMIYA S. Prostaglandins, and chronic inflammation. Trends Pharmacol Sci 2012; 33: 304-311.
    • (2012) Trends Pharmacol Sci , vol.33 , pp. 304-311
    • Aoki, T.1    Narumiya, S.2
  • 113
    • 33747885659 scopus 로고    scopus 로고
    • Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: Their role, and involvement in neurological disorders
    • PHILLIS JW, HORROCKS LA, FAROOQUI AA. Cyclooxygenases, lipoxygenases, and epoxygenases in CNS: their role, and involvement in neurological disorders. Brain Res Rev 2006; 52: 201-243.
    • (2006) Brain Res Rev , vol.52 , pp. 201-243
    • Phillis, J.W.1    Horrocks, L.A.2    Farooqui, A.A.3
  • 114
    • 0034651103 scopus 로고    scopus 로고
    • Cyclooxygenase2 contributes to functional hyperemia in whiskerbarrel cortex
    • NIWA K, ARAKI E, MORHAM SG, ROSS ME, IADECOLA C. Cyclooxygenase2 contributes to functional hyperemia in whiskerbarrel cortex. J Neurosci 2000; 20: 763-770.
    • (2000) J Neurosci , vol.20 , pp. 763-770
    • Niwa, K.1    Araki, E.2    Morham, S.G.3    Ross, M.E.4    Iadecola, C.5
  • 115
    • 84931050027 scopus 로고    scopus 로고
    • Inhibition of the prostaglandindegrading enzyme 15PGDH potentiates tissue regeneration
    • TISSUE REGENERATION. aaa2340
    • ZHANG Y, DESAI A, YANG SY, et al. TISSUE REGENERATION. Inhibition of the prostaglandindegrading enzyme 15PGDH potentiates tissue regeneration. Science 2015; 348: aaa2340.
    • (2015) Science , vol.348
    • Zhang, Y.1    Desai, A.2    Yang, S.Y.3
  • 116
    • 0036099571 scopus 로고    scopus 로고
    • Selective COX2 inhibitors, and dual acting antiinflammatory drugs: Critical remarks
    • BERTOLINI A, OTTANI A, SANDRINI M. Selective COX2 inhibitors, and dual acting antiinflammatory drugs: critical remarks. Curr Med Chem 2002; 9: 1033-1043.
    • (2002) Curr Med Chem , vol.9 , pp. 1033-1043
    • Bertolini, A.1    Ottani, A.2    Sandrini, M.3
  • 117
    • 20744433041 scopus 로고    scopus 로고
    • Cyclooxygenase1, and 2 differently contribute to prostaglandin E2 syn thesis, and lipid peroxidation after in vivo activation of Nmethyl Daspartate receptors in rat hippocampus
    • PEPICELLI O, FEDELE E, BERARDI M, et al. Cyclooxygenase1, and 2 differently contribute to prostaglandin E2 synthesis, and lipid peroxidation after in vivo activation of Nmethyl Daspartate receptors in rat hippocampus. J Neurochem 2005; 93: 1561-1567.
    • (2005) J Neurochem , vol.93 , pp. 1561-1567
    • Pepicelli, O.1    Fedele, E.2    Berardi, M.3
  • 118
    • 29144524943 scopus 로고    scopus 로고
    • Cyclooxygenase 2 (COX2) inhibition increases the inflammatory response in the brain during systemic immune stimuli
    • BLAIS V, TURRIN NP, RIVEST S. Cyclooxygenase 2 (COX2) inhibition increases the inflammatory response in the brain during systemic immune stimuli. J Neurochem 2005; 95: 1563-1574.
    • (2005) J Neurochem , vol.95 , pp. 1563-1574
    • Blais, V.1    Turrin, N.P.2    Rivest, S.3
  • 119
    • 74549220751 scopus 로고    scopus 로고
    • COX2 inhibitors as antidepressants, and antipsychotics: Clinical evidence
    • MULLER N. COX2 inhibitors as antidepressants, and antipsychotics: clinical evidence. Curr Opin Investig Drugs 2010; 11: 31-42.
    • (2010) Curr Opin Investig Drugs , vol.11 , pp. 31-42
    • Muller, N.1
  • 120
    • 61849133439 scopus 로고    scopus 로고
    • Elevated cerebrospinal fluid levels of prostaglandin E2, and 15(S) hydroxyeicosatetraenoic acid in multiple sclerosis
    • MATTSSON N, YAONG M, ROSENGREN L, et al. Elevated cerebrospinal fluid levels of prostaglandin E2, and 15(S) hydroxyeicosatetraenoic acid in multiple sclerosis. J Intern Med 2009; 265: 459-464.
    • (2009) J Intern Med , vol.265 , pp. 459-464
    • Mattsson, N.1    Yaong, M.2    Rosengren, L.3
  • 121
    • 59349102320 scopus 로고    scopus 로고
    • Genetic disruption of cyclooxygenase2 does not improve histological or behavioral outcome after traumatic brain injury in mice
    • AHMAD M, ROSE ME, VAGNI V, et al. Genetic disruption of cyclooxygenase2 does not improve histological or behavioral outcome after traumatic brain injury in mice. J Neurosci Res 2008; 86: 3605-3612.
    • (2008) J Neurosci Res , vol.86 , pp. 3605-3612
    • Ahmad, M.1    Rose, M.E.2    Vagni, V.3
  • 122
    • 33646708039 scopus 로고    scopus 로고
    • Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: A pilot openlabel study
    • MENDLEWICZ J, KRIWIN P, OSWALD P, SOUERY D, ALBONI S, BRUNELLO N. Shortened onset of action of antidepressants in major depression using acetylsalicylic acid augmentation: a pilot openlabel study. Int Clin Psychopharmacol 2006; 21: 227-231.
    • (2006) Int Clin Psychopharmacol , vol.21 , pp. 227-231
    • Mendlewicz, J.1    Kriwin, P.2    Oswald, P.3    Souery, D.4    Alboni, S.5    Brunello, N.6
  • 123
    • 40349100270 scopus 로고    scopus 로고
    • Endogenous proresolving, and antiinflammatory lipid mediators: A new pharmacologic genus
    • SERHAN CN, CHIANG N. Endogenous proresolving, and antiinflammatory lipid mediators: a new pharmacologic genus. Br J Pharmacol 2008; 153(Suppl. 1): S200-S215.
    • (2008) Br J Pharmacol , vol.153 , pp. S200-S215
    • Serhan, C.N.1    Chiang, N.2
  • 124
    • 0037160078 scopus 로고    scopus 로고
    • Metabolism of the endocannabinoids, 2arachidonylglycerol, and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters, and ethanolamides
    • KOZAK KR, CREWS BC, MORROW JD, et al. Metabolism of the endocannabinoids, 2arachidonylglycerol, and anandamide, into prostaglandin, thromboxane, and prostacyclin glycerol esters, and ethanolamides. J Biol Chem 2002; 277: 44877-44885.
    • (2002) J Biol Chem , vol.277 , pp. 44877-44885
    • Kozak, K.R.1    Crews, B.C.2    Morrow, J.D.3
  • 125
    • 42349099119 scopus 로고    scopus 로고
    • Endocannabinoids, and the brain immune system new neurones at the horizon?
    • WOLF SA, ULLRICH O. Endocannabinoids, and the brain immune system: new neurones at the horizon? J Neuroendocrinol 2008; 20(Suppl. 1): 15-19.
    • (2008) J Neuroendocrinol , vol.20 , pp. 15-19
    • Wolf, S.A.1    Ullrich, O.2
  • 126
    • 84879785100 scopus 로고    scopus 로고
    • Prostaglandin receptor EP2 in the crosshairs of antiinflammation, anticancer, and neuroprotection
    • JIANG J, DINGLEDINE R. Prostaglandin receptor EP2 in the crosshairs of antiinflammation, anticancer, and neuroprotection. Trends Pharmacol Sci 2013; 34: 413-423.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 413-423
    • Jiang, J.1    Dingledine, R.2
  • 127
    • 84864506490 scopus 로고    scopus 로고
    • Celecoxib enhances the effect of reboxetine, and fluoxetine on cortical noradrenaline, and serotonin output in the rat
    • JOHANSSON D, FALK A, MARCUS MM, SVENSSON TH. Celecoxib enhances the effect of reboxetine, and fluoxetine on cortical noradrenaline, and serotonin output in the rat. Prog Neuropsychopharmacol Biol Psychiatry 2012; 39: 143-148.
    • (2012) Prog Neuropsychopharmacol Biol Psychiatry , vol.39 , pp. 143-148
    • Johansson, D.1    Falk, A.2    Marcus, M.M.3    Svensson, T.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.