Phosphodiesterase genes are associated with susceptibility to major depression and antidepressant treatment response

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 41, 2006, Pages 15124-15129

  Wong, Ma Li ^a   Whelan, Fiona ^b   Deloukas, Panagiotis ^d   Whittaker, Pamela ^d   Delgado, Marcos ^d   Cantor, Rita M ^c   McCann, Samuel M ^e   Licinio, Julio ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

cGMP; Gene association; Mexican American; Pharmacogenetics; SNP

Indexed keywords

ANTIDEPRESSANT AGENT; CYCLIC AMP; CYCLIC GMP; CYCLIC NUCLEOTIDE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASE; DESIPRAMINE; FLUOXETINE; GENOMIC DNA; GROWTH FACTOR; HORMONE DERIVATIVE; NEUROTRANSMITTER; NITRIC OXIDE; PHOSPHODIESTERASE; PROTEIN PDE11A; PROTEIN PDE1A; PROTEIN PDE9A; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HISPANIC; HUMAN; LEARNING; MAJOR CLINICAL STUDY; MAJOR DEPRESSION; MALE; MEMORY; MOOD; MULTIGENE FAMILY; NERVOUS SYSTEM FUNCTION; PATHOGENESIS; PATHOPHYSIOLOGY; PHARMACOGENETICS; PRIORITY JOURNAL; PROSPECTIVE STUDY; REMISSION; SECOND MESSENGER; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME; TREATMENT RESPONSE;

ADULT; AGED; ANTIDEPRESSIVE AGENTS; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 1; DEPRESSIVE DISORDER, MAJOR; DESIPRAMINE; DOUBLE-BLIND METHOD; FEMALE; FLUOXETINE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MEXICAN AMERICANS; MIDDLE AGED; PHOSPHORIC DIESTER HYDROLASES; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD;

EID: 33750061011     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0602795103     Document Type: Article

References (63)

1. Beavo JA (1995) Physiol Rev 75:725-748.
2. Beavo JA, Conti M, Heaslip RJ (1994) Mol Pharmacol 46:399-405.
3. Soderling SH, Bayuga SJ, Beavo JA (1998) Proc Natl Acad Sci USA 95:8991-8996.
4. Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB (1998) Biochem Biophys Res Commun 246:570-577.
5. Hayashi M, Matsushima K, Ohashi H, Tsunoda H, Murase S, Kawarada Y, Tanaka T (1998) Biochem Biophys Res Commun 250:751-756.
6. Soderling SH, Bayuga SJ, Beavo JA (1998) J Biol Chem 273:15553-15558.
7. Fisher DA, Smith JF, Pillar JS, St Denis SH, Cheng JB (1998) J Biol Chem 273:15559-15564.
8. Soderling SH, Bayuga SJ, Beavo JA (1999) Proc Natl Acad Sci USA 96:7071-7076.
9. Fawcett L, Baxendale R, Stacey P, McGrouther C, Harrow I, Soderling S, Hetman J, Beavo JA, Phillips SC (2000) Proc Natl Acad Sci USA 97:3702-3707.
10. Jeon YH, Heo YS, Kim CM, Hyun YL, Lee TG, Ro S, Cho JM (2005) Cell Mol Life Sci 62:1198-1220.
11. Bolger GB (1994) Cell Signal 6:851-859.
12. Houslay MD (1998) Semin Cell Dev Biol 9:161-167.
13. Perry MJ, Higgs GA (1998) Curr Opin Chem Biol 2:472-481.
14. Mehats C, Andersen CB, Filopanti M, Jin SL, Conti M (2002) Trends Endocrinol Metab 13:29-35.
15. Rotella DP (2002) Nat Rev Drug Discov 1:674-682.
16. Conti M, Nemoz G, Sette C, Vicini E (1995) Endocr Rev 16:370-389.
17. Torphy TJ (1998) Am J Respir Crit Care Med 157:351-370.
18. Beavo JA, Brunton LL (2002) Nat Rev Mol Cell Biol 3:710-718.
19. Conti M (2000) Mol Endocrinol 14:1317-1327.
20. Houslay MD, Adams DR (2003) Biochem J 370:1-18.
21. Sonnenburg WK, Seget D, Kwak KS, Huang J, Charbonneau H, Beavo JA (1995) J Biol Chem 270:30989-31000.
22. Menniti FS, Faraci WS, Schmidt CJ (2006) Nat Rev Drug Discov 5:660-670.
23. Houslay MD (2001) Prog Nucleic Acid Res Mol Biol 69:249-315.
24. Zhang HT, O'Donnell JM (2000) Psychopharmacology (Berl) 150:311-316.
25. Zhang HT, Crissman AM, Dorairaj NR, Chandler LJ, O'Donnell JM (2000) Neuropsychopharmacology 23:198-204.
26. Perez J, Tardito D, Racagni G, Smeraldi E, Zanardi R (2001) Mol Psychiatry 6:44-49.
27. O'Donnell JM, Frith S, Wilkins J (1994) J Pharmacol Exp Ther 271:246-254.
28. Zhang HT, Huang Y, Jin SL, Frith SA, Suvarna N, Conti M, O'Donnell JM (2002) Neuropsychopharmacology 27:587-595.
29. Torgersen S (1986) Arch Gen Psychiatry 43:222-226.
30. McGuffin P, Katz R, Rutherford J (1991) Psychol Med 21:329-335.
31. McGuffin P, Katz R, Watkins S, Rutherford J (1996) Arch Gen Psychiatry 53:129-136.
32. Kendler KS, Gardner CO, Neale MC, Prescott CA (2001) Psychol Med 31:605-616.
33. Kendler KS, Neale MC, Kessler RC, Heath AC, Eaves LJ (1993) Arch Gen Psychiatry 50:863-870.
34. Bierut LJ, Heath AC, Bucholz KK, Dinwiddie SH, Madden PA, Statham DJ, Dunne MP, Martin NG (1999) Arch Gen Psychiatry 56:557-563.
35. Sullivan PF, Neale MC, Kendler KS (2000) Am J Psychiatry 157:1552-1562.
36. Yuasa K, Kanoh Y, Okumura K, Omori K (2001) Eur J Biochem 268:168-178.
37. Hebb AL, Robertson HA, Denovan-Wright EM (2004) Neuroscience 123:967-981.
38. Hu H, McCaw EA, Hebb AL, Gomez GT, Denovan-Wright EM (2004) Eur J Neurosci 20:3351-3363.
39. Wayman C, Phillips S, Lunny C, Webb T, Fawcett L, Baxendale R, Burgess G (2005) Int J Impot Res 17:216-223.
40. Makhlouf A, Kshirsagar A, Niederberger C (2006) Int J Impot Res, in press.
41. Wang X, Robinson PJ (1997) J Neurochem 68:443-456.
42. Feil S, Zimmermann P, Knorn A, Brummer S, Schlossmann J, Hofmann F, Feil R (2005) Neuroscience 135:863-868.
43. Hofmann F (2005) J Biol Chem 280:1-4.
44. Feil R, Feil S, Hofmann F (2005) Trends Mol Med 11:71-75.
45. Scholz NL, Truman JW (2000) in Functional Neuroanatomy of the Nitric Oxide System, eds Steinbusch HWM, De Vente J, Vincent SR (Elsevier, Amsterdam), pp 417-441.
46. Bicker G (2001) Arch Insect Biochem Physiol 48:100-110.
47. Scholz NL, de Vente J, Truman JW, Graubard K (2001) J Neurosci 21:1610-1618.
48. Song H, Ming G, He Z, Lehmann M, McKerracher L, Tessier-Lavigne M, Poo M (1998) Science 281:1515-1518.
49. Song HJ, Poo MM (1999) Curr Opin Neurobiol 9:355-363.
50. Polleux F, Morrow T, Ghosh A (2000) Nature 404:567-573.
51. Kendrick KM, Guevara-Guzman R, Zorrilla J, Hinton MR, Broad KD, Mimmack M, Ohkura S (1997) Nature 388:670-674.
52. Bernabeu R, Cammarota M, Izquierdo I, Medina JH (1997) Braz J Med Biol Res 30:961-965.
53. Izquierdo LA, Vianna M, Barros DM, Mello e Souza T, Ardenghi P, Sant'Anna MK, Rodrigues C, Medinam JH, Izquierdo I (2000) Neurobiol Learn Mem 73:141-149.
54. Horvath A, Boikos S, Giatzakis C, Robinson-White A, Groussin L, Griffin KJ, Stein E, Levine E, Delimpasi G, Hsiao HP, et al. (2006) Nat Genet 38:794-800.
55. Licinio J, O'Kirwan F, Irizarry K, Merriman B, Thakur S, Jepson R, Lake S, Tantisira KG, Weiss ST, Wong ML (2004) Mol Psychiatry 9:1075-1082.
56. American Psychiatric Association (1994) Diagnostic and Statistical Manual of Mental Disorders (American Psychiatric Association, Washington, DC).
57. Hazuda HP, Comeaux PJ, Stern MP, Haffner SM, Eifler CW, Rosenthal M (1986) Am J Epidemiol 123:96-112.
58. Hamilton M (1960) J Neurol Neurosurg Psychiatry 23:56-62.
59. Fan JB, Oliphant A, Shen R, Kermani BG, Garcia F, Gunderson KL, Hansen M, Steemers F, Butler SL, Deloukas P, et al. (2003) Cold Spring Harbor Symp Quant Biol 68:69-78.
60. Weir BS (1996) Genetic Data Analysis II: Methods for Discrete Population Genetic Data (Sinauer Associates, Sunderland, MA).
61. Wang N, Akey JM, Zhang K, Chakraborty R, Jin L (2002) Am J Hum Genet 71:1227-1234.
62. Barrett JC, Fry B, Maller J, Daly MJ (2005) Bioinformatics 21:263-265.
63. Sasieni PD (1997) Biometrics 53:1253-1261.