Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli

Journal of Neurochemistry

Volumn 95, Issue 6, 2005, Pages 1563-1574

  Blais, Véronique ^a   Turrin, Nicolas P ^a   Rivest, Serge ^a  

^a LAVAL UNIVERSITY   (Canada)

Author keywords

Blood brain barrier; Cytokines; Inflammation; Microglia; Non steroidal anti inflammatory drugs; Prostaglandins

Indexed keywords

5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; ENDOTOXIN; GLUCOCORTICOID; INDOMETACIN; KETOROLAC; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN E2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CELL; BRAIN TISSUE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME INHIBITION; GENE EXPRESSION REGULATION; HYBRIDIZATION; IMMUNOSTIMULATION; INFLAMMATION; INNATE IMMUNITY; MALE; MICROGLIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMIC CIRCULATION;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DINOPROSTONE; GENE EXPRESSION; IN SITU HYBRIDIZATION; INDOMETHACIN; INFLAMMATION; INTRAMOLECULAR OXIDOREDUCTASES; KETOROLAC; LIPOPOLYSACCHARIDES; MALE; MICE; NITROBENZENES; PLASMIDS; PYRAZOLES; SULFONAMIDES;

ANIMALIA;

EID: 29144524943     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2005.03480.x     Document Type: Article

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