Structural basis for the mutual antagonism of cAMP and TRIP8b in regulating HCN channel function

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 40, 2014, Pages 14577-14582

  Saponaro, Andrea ^a   Pauleta, Sofia R ^b   Cantini, Francesca ^c   Matzapetakis, Manolis ^d   Hammann, Christian ^e   Donadoni, Chiara ^a   Hu, Lei ^f   Thiel, Gerhard ^g   Banci, Lucia ^c   Santoro, Bina ^g   Moroni, Anna ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b DEPARTAMENTO DE QUÍMICA   (Portugal)

^c UNIVERSITY OF FLORENCE   (Italy)

^d INSTITUTO DE TECNOLOGIA QUÍMICA E BIOLÓGICA   (Portugal)

^e JACOBS UNIVERSITY BREMEN   (Germany)

^f Och Spine at New York Presbyterian Hospitals   (United States)

^g DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CYCLIC AMP; HYPERPOLARIZATION ACTIVATED CYCLIC NUCLEOTIDE GATED CHANNEL; TETRATRICOPEPTIDE REPEAT CONTAINING RAB8B INTERACTING PROTEIN; UNCLASSIFIED DRUG; CELL RECEPTOR; CYCLIC NUCLEOTIDE GATED CHANNEL; HCN2 PROTEIN, HUMAN; PEX5R PROTEIN, HUMAN; POTASSIUM CHANNEL; PROTEIN BINDING;

BINDING SITE; CHANNEL GATING; CONCENTRATION CAMP; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; ESCHERICHIA COLI; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; MUTAGENESIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN QUATERNARY STRUCTURE; PROTEIN STRUCTURE; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; CYCLIC AMP; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; HYPERPOLARIZATION-ACTIVATED CYCLIC NUCLEOTIDE-GATED CHANNELS; ION CHANNEL GATING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; POTASSIUM CHANNELS; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CYTOPLASMIC AND NUCLEAR;

EID: 84907681174     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1410389111     Document Type: Article

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