The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets

PLoS Genetics

Volumn 12, Issue 12, 2016, Pages

  Keller, Mark P ^a   Paul, Pradyut K ^a   Rabaglia, Mary E ^a   Stapleton, Donnie S ^a   Schueler, Kathryn L ^a   Broman, Aimee Teo ^b   Ye, Shuyun Isabella ^c   Leng, Ning ^b   Brandon, Christopher J ^a   Neto, Elias Chaibub ^d   Plaisier, Christopher L ^e   Simonett, Shane P ^a   Kebede, Melkam A ^a   Sheynkman, Gloria M ^a   Klein, Mark A ^a   Baliga, Nitin S ^e   Smith, Lloyd M ^a   Broman, Karl W ^b   Yandell, Brian S ^c   Kendziorski, Christina ^b   Attie, Alan D ^a   more..

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c University of Wisconsin Madison   (United States)

^d SAGE BIONETWORKS   (United States)

^e INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; NFATC2 PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; NFATC1 PROTEIN, MOUSE; NFATC2 PROTEIN, MOUSE; TRANSCRIPTION FACTOR NFAT;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHROMOSOME 2; CONTROLLED STUDY; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; GENETIC LINKAGE; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; INSULIN RELEASE; MOUSE; NFATC2 GENE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; CHROMOSOMAL MAPPING; GENETICS; GENOME; GENOME-WIDE ASSOCIATION STUDY; METABOLISM; MOUSE MUTANT; PANCREAS ISLET; PATHOLOGY; PROMOTER REGION;

ANIMALS; CELL PROLIFERATION; CHROMOSOME MAPPING; DIABETES MELLITUS, TYPE 2; GENE EXPRESSION REGULATION; GENETIC LINKAGE; GENOME; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INSULIN; INSULIN-SECRETING CELLS; ISLETS OF LANGERHANS; MICE; MICE, OBESE; NFATC TRANSCRIPTION FACTORS; PROMOTER REGIONS, GENETIC;

EID: 85007524451     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006466     Document Type: Article

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