Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance

Molecular Endocrinology

Volumn 25, Issue 11, 2011, Pages 1904-1914

  Schaffer, Ashleigh E ^a,b   Yang, Almira J ^b   Thorel, Fabrizio ^c   Herrera, Pedro L ^c   Sander, Maike ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; GLUCOSE; TRANSCRIPTION FACTOR NKX6.1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL REGENERATION; GENE OVEREXPRESSION; GLUCOSE METABOLISM; GLUCOSE TOLERANCE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PANCREAS ISLET CELL FUNCTION; PRIORITY JOURNAL;

ANIMALS; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOSE; HOMEODOMAIN PROTEINS; IMMUNOBLOTTING; INSULIN-SECRETING CELLS; MICE; MICE, TRANSGENIC;

MUS;

EID: 80054997189     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2011-1010     Document Type: Article

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