In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

Cell

Volumn 167, Issue 7, 2016, Pages 1719-1733.e12

  Ocampo, Alejandro ^a   Reddy, Pradeep ^a   Martinez Redondo, Paloma ^a   Platero Luengo, Aida ^a   Hatanaka, Fumiyuki ^a   Hishida, Tomoaki ^a   Li, Mo ^a   Lam, David ^a   Kurita, Masakazu ^a,b   Beyret, Ergin ^a   Araoka, Toshikazu ^a,b   Vazquez Ferrer, Eric ^a   Donoso, David ^a   Roman, Jose Luis ^a   Xu, Jinna ^a   Rodriguez Esteban, Concepcion ^a   Nuñez, Gabriel ^c   Nuñez Delicado, Estrella ^b   Campistol, Josep M ^d   Guillen, Isabel ^e   Guillen, Pedro ^e   Izpisua Belmonte, Juan Carlos ^a   more..

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b CATHOLIC UNIVERSITY OF MURCIA   (Spain)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF BARCELONA   (Spain)

^e Clinica Centro Fundación Pedro Guillén   (Spain)

Author keywords

aging; cellular reprogramming; epigenetics; lifespan

Indexed keywords

BETA GALACTOSIDASE; COLLAGENASE 3; HISTONE H2AX; INTERLEUKIN 1ALPHA; INTERLEUKIN 6; KRUPPEL LIKE FACTOR 4; LAMIN A; LAMIN C; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; P53 BINDING PROTEIN 1; REACTIVE OXYGEN METABOLITE; STAGE SPECIFIC EMBRYO ANTIGEN 1; THY 1 ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; LMNA PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARCINOGENESIS; CELL AGING; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DOWN REGULATION; EPIGENETICS; IN VIVO STUDY; METABOLIC DISORDER; MOUSE; MUSCLE INJURY; NONHUMAN; NUCLEAR REPROGRAMMING; PHENOTYPE; PREMATURE AGING; PRIORITY JOURNAL; PROTEIN EXPRESSION; AGING; ANIMAL; CHEMICALLY INDUCED; GENETIC EPIGENESIS; GENETICS; HUMAN; INDUCED PLURIPOTENT STEM CELL; METABOLIC DISEASES; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS; SARCOPENIA;

AGING; AGING, PREMATURE; ANIMALS; CELLULAR REPROGRAMMING; DIABETES MELLITUS, TYPE 2; EPIGENESIS, GENETIC; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LAMIN TYPE A; METABOLIC DISEASES; MICE; MODELS, ANIMAL; PANCREAS; SARCOPENIA; TRANSCRIPTION FACTORS;

EID: 85006243183     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.11.052     Document Type: Article

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