Generation of a drug-inducible reporter system to study cell reprogramming in human cells

Journal of Biological Chemistry

Volumn 287, Issue 48, 2012, Pages 40767-40778

  Ruiz, Sergio ^a   Panopoulos, Athanasia D ^a   Montserrat, Nuria ^b   Multon, Marie Christine ^c   Daury, Aurélie ^c   Rocher, Corinne ^c   Spanakis, Emmanuel ^c   Batchelder, Erika M ^a   Orsini, Cécile ^c   Deleuze, Jean François ^c,d   Izpisua Belmonte, Juan Carlos ^a,b  

^a SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^b CENTER OF REGENERATIVE MEDICINE IN BARCELONA   (Spain)

^c SANOFI   (France)

^d DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CELL LINES; CELLULAR SYSTEM; CHEMICAL SCREENING; HUMAN CELLS; MICRORNAS; MOUSE CELLS; PLURIPOTENT STEM CELLS; PROOF OF PRINCIPLES; REPORTER SYSTEMS; SOMATIC CELLS;

CATALYST ACTIVITY; CELL CULTURE; GENES; MAMMALS; STEM CELLS; TRANSCRIPTION FACTORS;

EFFICIENCY;

DOXYCYCLINE; HSA MICRORNA 519A; MICRORNA; OCTAMER TRANSCRIPTION FACTOR 4; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CELL REPROGRAMMING; CELL SCREENING; DRUG INDUCIBLE HUMAN REPROGRAMMING REPORTER SYSTEM; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LIBRARY; HUMAN; HUMAN CELL; LENTIVIRINAE; MARKER GENE; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; PROMOTER REGION; REPORTER GENE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; CYTOLOGICAL TECHNIQUES; DOXYCYCLINE; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; LENTIVIRUS; MICE; MICRORNAS; STEM CELLS;

EID: 84869989392     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.384024     Document Type: Article

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