IDH1 and IDH2 mutations as novel therapeutic targets: Current perspectives

Journal of Blood Medicine

Volumn 7, Issue , 2016, Pages 171-180

  Mondesir, Johanna ^a,b   Willekens, Christophe ^c,d   Touat, Mehdi ^c,e   de Botton, Stéphane ^c,d  

^a SAINT LOUIS HOSPITAL   (France)

^b INSTITUT COCHIN   (France)

^c INSTITUT GUSTAVE ROUSSY   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

2 HG; Acute myeloid leukemia; Epigenetic; Glioma; IDH1; IDH2; Oncogene; Targeted therapies; Tumor metabolism

Indexed keywords

2 OXOGLUTARIC ACID; DNA METHYLTRANSFERASE; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PROTEIN BCL 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE;

BRAIN TUMOR; CANCER CELL; CELL DIFFERENTIATION; DNA METHYLATION; DRUG TARGETING; EPIGENETICS; GENE EXPRESSION; GENE MUTATION; HEMATOLOGIC MALIGNANCY; HISTONE METHYLATION; HUMAN; IMMUNOTHERAPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SOLID TUMOR;

EID: 85006086265     PISSN: None     EISSN: 11792736     Source Type: Journal    
DOI: 10.2147/JBM.S70716     Document Type: Review

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