Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma

Clinical Cancer Research

Volumn 20, Issue 7, 2014, Pages 1884-1890

  Borger, Darrell R ^a   Goyal, Lipika ^a   Yau, Thomas ^c   Poon, Ronnie T ^c   Ancukiewicz, Marek ^a   Deshpande, Vikram ^a   Christiani, David C ^a   Liebman, Hannah M ^a   Yang, Hua ^b   Kim, Hyeryun ^b   Yen, Katharine ^b   Faris, Jason E ^a   Iafrate, A John ^a   Kwak, Eunice L ^a   Clark, Jeffrey W ^a   Allen, Jill N ^a   Blaszkowsky, Lawrence S ^a   Murphy, Janet E ^a   Saha, Supriya K ^a   Hong, Theodore S ^a   Wo, Jennifer Y ^a   Ferrone, Cristina R ^a   Tanabe, Kenneth K ^a   Bardeesy, Nabeel ^a   Straley, Kimberly S ^b   Agresta, Sam ^b   Schenkein, David P ^b   Ellisen, Leif W ^a   Ryan, David P ^a   Zhu, Andrew X ^a   more..

^a HARVARD MEDICAL SCHOOL   (United States)

^b AGIOS PHARMACEUTICALS   (United States)

^c UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

2 HYDROXYGLUTARIC ACID; GEMCITABINE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; OXALIPLATIN; PANITUMUMAB; ALPHA-HYDROXYGLUTARATE; GLUTARIC ACID DERIVATIVE; IDH1 PROTEIN, HUMAN; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 2, HUMAN; TUMOR MARKER;

ADULT; AGED; ALLELE; ARTICLE; BILE DUCT CARCINOMA; CANCER GRADING; CANCER SCREENING; CANCER SURGERY; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FEMALE; GENE; GENE MUTATION; GENOTYPE; HUMAN; IDH1 GENE; IDH2 GENE; LIQUID CHROMATOGRAPHY; MALE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TUMOR VOLUME; WILD TYPE; BILE DUCT TUMOR; BLOOD; GENETICS; INTRAHEPATIC BILE DUCT; MIDDLE AGED; MUTATION; PATHOLOGY;

ADULT; AGED; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CHOLANGIOCARCINOMA; FEMALE; GLUTARATES; HUMANS; ISOCITRATE DEHYDROGENASE; MALE; MIDDLE AGED; MUTATION; TUMOR MARKERS, BIOLOGICAL;

EID: 84898766502     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-13-2649     Document Type: Article

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