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Volumn 18, Issue 2, 2016, Pages 283-290

Integration of 2-hydroxyglutarate-proton magnetic resonance spectroscopy into clinical practice for disease monitoring in isocitrate dehydrogenase-mutant glioma

(27)  De La Fuente, MacArena I a,c,g   Young, Robert J a   Rubel, Jennifer a   Rosenblum, Marc a   Tisnado, Jamie a   Briggs, Samuel a   Arevalo Perez, Julio a   Cross, Justin R a   Campos, Carl a   Straley, Kimberly b   Zhu, Dongwei b   Dong, Chuanhui c   Thomas, Alissa a   Omuro, Antonio A a   Nolan, Craig P a   Pentsova, Elena a   Kaley, Thomas J a   Oh, Jung H a   Noeske, Ralph d   Maher, Elizabeth e   more..


Author keywords

cancer metabolism; glioma; IDH; imaging biomarker; magnetic resonance spectroscopy; R 2 hydroxyglutarate

Indexed keywords

2 HYDROXYGLUTARIC ACID; ISOCITRATE DEHYDROGENASE; ISOCITRATE DEHYDROGENASE 1; ISOCITRATE DEHYDROGENASE 2; ALPHA-HYDROXYGLUTARATE; GLUTARIC ACID DERIVATIVE;

EID: 84960430663     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/nov307     Document Type: Article
Times cited : (159)

References (31)
  • 1
    • 65349150503 scopus 로고    scopus 로고
    • IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
    • Watanabe T, Nobusawa S, Kleihues P, Ohgaki H. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol. 2009;174(4):1149-1153.
    • (2009) Am J Pathol , vol.174 , Issue.4 , pp. 1149-1153
    • Watanabe, T.1    Nobusawa, S.2    Kleihues, P.3    Ohgaki, H.4
  • 2
    • 84892373020 scopus 로고    scopus 로고
    • Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma
    • Johnson BE, Mazor T, Hong C, et al. Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma. Science. 2014;343(6167):189-193.
    • (2014) Science , vol.343 , Issue.6167 , pp. 189-193
    • Johnson, B.E.1    Mazor, T.2    Hong, C.3
  • 3
    • 84862776918 scopus 로고    scopus 로고
    • Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation
    • Koivunen P, Lee S, Duncan CG, et al. Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation. Nature. 2012;483(7390):485-U144.
    • (2012) Nature , vol.483 , Issue.7390 , pp. 485-U144
    • Koivunen, P.1    Lee, S.2    Duncan, C.G.3
  • 4
    • 84858796263 scopus 로고    scopus 로고
    • IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
    • Turcan S, Rohle D, Goenka A, et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype. Nature. 2012; 483(7390):479-483.
    • (2012) Nature , vol.483 , Issue.7390 , pp. 479-483
    • Turcan, S.1    Rohle, D.2    Goenka, A.3
  • 5
    • 77952108366 scopus 로고    scopus 로고
    • Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma
    • Noushmehr H, Weisenberger DJ, Diefes K, et al. Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 2010;17(5):510-522.
    • (2010) Cancer Cell , vol.17 , Issue.5 , pp. 510-522
    • Noushmehr, H.1    Weisenberger, D.J.2    Diefes, K.3
  • 6
    • 84877632013 scopus 로고    scopus 로고
    • An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
    • Rohle D, Popovici-Muller J, Palaskas N, et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science. 2013;340(6132):626-630.
    • (2013) Science , vol.340 , Issue.6132 , pp. 626-630
    • Rohle, D.1    Popovici-Muller, J.2    Palaskas, N.3
  • 7
    • 84907980918 scopus 로고    scopus 로고
    • Clinical safety and activity in a phase i trial of AG-221, a first in class, potent inhibitor of the IDH2-mutant protein, in patients with IDH2 mutant positive advanced hematologic malignancies [abstract]
    • Apr 5-9; San Diego, CA, Philadelphia (PA): AACR
    • Stein E, Tallman M, Pollyea DA, et al. Clinical safety and activity in a phase I trial of AG-221, a first in class, potent inhibitor of the IDH2-mutant protein, in patients with IDH2 mutant positive advanced hematologic malignancies [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research, 2014 Apr 5-9; San Diego, CA, Philadelphia (PA): AACR;
    • (2014) Proceedings of the 105th Annual Meeting of the American Association for Cancer Research
    • Stein, E.1    Tallman, M.2    Pollyea, D.A.3
  • 8
    • 85032653564 scopus 로고    scopus 로고
    • Cancer Res. 2014;74(Suppl 19):103.
    • (2014) Cancer Res. , vol.74 , pp. 103
  • 9
    • 72049125350 scopus 로고    scopus 로고
    • Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
    • Dang L, White DW, Gross S, et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate. Nature. 2009;462(7274): 739-744.
    • (2009) Nature , vol.462 , Issue.7274 , pp. 739-744
    • Dang, L.1    White, D.W.2    Gross, S.3
  • 10
    • 84875496294 scopus 로고    scopus 로고
    • (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible
    • Losman JA, Looper RE, Koivunen P, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013;339(6127):1621-1625.
    • (2013) Science , vol.339 , Issue.6127 , pp. 1621-1625
    • Losman, J.A.1    Looper, R.E.2    Koivunen, P.3
  • 11
    • 84859554794 scopus 로고    scopus 로고
    • 2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size
    • Capper D, Simon M, Langhans CD, et al. 2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size. Int J Cancer. 2012;131(3):766-768.
    • (2012) Int J Cancer , vol.131 , Issue.3 , pp. 766-768
    • Capper, D.1    Simon, M.2    Langhans, C.D.3
  • 12
    • 84855710482 scopus 로고    scopus 로고
    • Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy
    • Andronesi OC, Kim GS, Gerstner E, et al. Detection of 2-hydroxyglutarate in IDH-mutated glioma patients by in vivo spectral-editing and 2D correlation magnetic resonance spectroscopy. Sci Transl Med. 2012;4(116):1-22.
    • (2012) Sci Transl Med , vol.4 , Issue.116 , pp. 1-22
    • Andronesi, O.C.1    Kim, G.S.2    Gerstner, E.3
  • 13
    • 84862776826 scopus 로고    scopus 로고
    • 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas
    • Choi C, Ganji SK, DeBerardinis RJ, et al. 2-hydroxyglutarate detection by magnetic resonance spectroscopy in IDH-mutated patients with gliomas. Nat Med. 2012;18(4):624-629.
    • (2012) Nat Med , vol.18 , Issue.4 , pp. 624-629
    • Choi, C.1    Ganji, S.K.2    DeBerardinis, R.J.3
  • 14
  • 15
    • 0142094100 scopus 로고    scopus 로고
    • 1H and13C NMR study of 2-hydroxyglutaric acid and its lactone
    • Bal D, Gryff-Keller A. 1H and13C NMR study of 2-hydroxyglutaric acid and its lactone. Magn Reson Chem. 2002;40(8):533-536.
    • (2002) Magn Reson Chem , vol.40 , Issue.8 , pp. 533-536
    • Bal, D.1    Gryff-Keller, A.2
  • 16
    • 0034099574 scopus 로고    scopus 로고
    • Proton NMR chemical shifts and coupling constants for brain metabolites
    • Govindaraju V, Young K, Maudsley A. Proton NMR chemical shifts and coupling constants for brain metabolites. NMR Biomed. 2000;13:129-153.
    • (2000) NMR Biomed , vol.13 , pp. 129-153
    • Govindaraju, V.1    Young, K.2    Maudsley, A.3
  • 18
    • 0031425055 scopus 로고    scopus 로고
    • Theory and application of array coils in MR spectroscopy
    • Wright S, Wald L. Theory and application of array coils in MR spectroscopy. NMR Biomed. 1997;10:394-410.
    • (1997) NMR Biomed , vol.10 , pp. 394-410
    • Wright, S.1    Wald, L.2
  • 19
    • 0011600888 scopus 로고    scopus 로고
    • Improvement of the analytical quality of MR spectroscopy data by frequency corrected averaging [abstract]
    • Schubert FSF, Elster C, Link A, et al. Improvement of the analytical quality of MR spectroscopy data by frequency corrected averaging [abstract]. Magn Reson Mat Physiol Biol Med. 2000;11(Suppl. 1): 189.
    • (2000) Magn Reson Mat Physiol Biol Med , vol.11 , pp. 189
    • Schubert, F.S.F.1    Elster, C.2    Link, A.3
  • 20
    • 0033040399 scopus 로고    scopus 로고
    • Sources of variability in the response of coupled spins to the PRESS sequence and their potential impact on metabolite quantification
    • Thompson R, Allen P. Sources of variability in the response of coupled spins to the PRESS sequence and their potential impact on metabolite quantification. Magn Reson Med. 1999;41(6): 1162-1169.
    • (1999) Magn Reson Med , vol.41 , Issue.6 , pp. 1162-1169
    • Thompson, R.1    Allen, P.2
  • 21
    • 84907053684 scopus 로고    scopus 로고
    • Advanced magnetic resonance imaging of the physical processes in human glioblastoma
    • Kalpathy-Cramer J, Gerstner ER, Emblem KE, Andronesi OC, Rosen B. Advanced magnetic resonance imaging of the physical processes in human glioblastoma. Cancer Res. 2014;74(17): 4622-4637.
    • (2014) Cancer Res , vol.74 , Issue.17 , pp. 4622-4637
    • Kalpathy-Cramer, J.1    Gerstner, E.R.2    Emblem, K.E.3    Andronesi, O.C.4    Rosen, B.5
  • 22
    • 0023636904 scopus 로고
    • Spatial localization in NMR spectroscopy in vivo
    • Bottonley P. Spatial localization in NMR spectroscopy in vivo. Ann N Y Acad Sci. 1987;508:333-348.
    • (1987) Ann N y Acad Sci , vol.508 , pp. 333-348
    • Bottonley, P.1
  • 23
    • 60849115270 scopus 로고    scopus 로고
    • IDH1 and IDH2 mutations in gliomas
    • Yan H, Parsons DW, Jin G, et al. IDH1 and IDH2 mutations in gliomas. N Engl J Med. 2009;360:765-773.
    • (2009) N Engl J Med , vol.360 , pp. 765-773
    • Yan, H.1    Parsons, D.W.2    Jin, G.3
  • 24
    • 84932628860 scopus 로고    scopus 로고
    • Comprehensive, integrative genomic analysis of diffuse lower-Grade gliomas
    • Cancer Genome Atlas Research N, Brat DJ, Verhaak RG, Aldape KD, et al. Comprehensive, integrative genomic analysis of diffuse lower-Grade gliomas. N Engl J Med. 2015;372(26): 2481-2498.
    • (2015) N Engl J Med , vol.372 , Issue.26 , pp. 2481-2498
    • Cancer Genome Atlas Research Brat N, D.J.1    Verhaak, R.G.2    Aldape, K.D.3
  • 25
    • 84932649039 scopus 로고    scopus 로고
    • Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors
    • Eckel-Passow JE, Lachance DH, Molinaro AM, et al. Glioma groups based on 1p/19q, IDH, and TERT promoter mutations in tumors. N Engl J Med. 2015;372(26):2499-2508.
    • (2015) N Engl J Med , vol.372 , Issue.26 , pp. 2499-2508
    • Eckel-Passow, J.E.1    Lachance, D.H.2    Molinaro, A.M.3
  • 27
    • 34247503858 scopus 로고    scopus 로고
    • Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults
    • Al-Okaili RN, Krejza J,Wang SM,Woo JH, Melhem ER. Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults. Radiographics. 2006;26:S173-SU84.
    • (2006) Radiographics , vol.26 , pp. S173-SU84
    • Al-Okaili, R.N.1    Krejza, J.2    Wang, S.M.3    Woo, J.H.4    Melhem, E.R.5
  • 29
    • 84879374380 scopus 로고    scopus 로고
    • Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia
    • DiNardo CD, Propert KJ, Loren AW, et al. Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia. Blood. 2013;121(24): 4917-4924.
    • (2013) Blood , vol.121 , Issue.24 , pp. 4917-4924
    • DiNardo, C.D.1    Propert, K.J.2    Loren, A.W.3
  • 30
    • 84870557152 scopus 로고    scopus 로고
    • Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response
    • Fathi AT, Sadrzadeh H, Borger DR, et al. Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response. Blood. 2012;120(23):4649-4652.
    • (2012) Blood , vol.120 , Issue.23 , pp. 4649-4652
    • Fathi, A.T.1    Sadrzadeh, H.2    Borger, D.R.3
  • 31
    • 77149134353 scopus 로고    scopus 로고
    • Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations
    • Gross S, Cairns RA, Minden MD, et al. Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations. J Exp Med. 2010;207(2):339-344.
    • (2010) J Exp Med , vol.207 , Issue.2 , pp. 339-344
    • Gross, S.1    Cairns, R.A.2    Minden, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.