-
1
-
-
34547122001
-
The 2007 WHOclassification of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD et al. The 2007 WHOclassification of tumours of the central nervous system. Acta Neuropathol 2007;114:97–109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
-
2
-
-
77954697566
-
Isocitrate dehydrogenase 1 and 2 mutationsincancer:Alterationsatacrossroadsofcellular metabolism
-
Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutationsincancer:Alterationsatacrossroadsofcellular metabolism. J Natl Cancer Inst 2010;102:932–941.
-
(2010)
J Natl Cancer Inst
, vol.102
, pp. 932-941
-
-
Reitman, Z.J.1
Yan, H.2
-
3
-
-
65349150503
-
IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas
-
Watanabe T, Nobusawa S, Kleihues P et al. IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas. Am J Pathol 2009;174:1149–1153.
-
(2009)
Am J Pathol
, vol.174
, pp. 1149-1153
-
-
Watanabe, T.1
Nobusawa, S.2
Kleihues, P.3
-
4
-
-
80055100987
-
Glioma IDH1 mutation patterns off the beaten track
-
Pusch S, Sahm F, Meyer J et al. Glioma IDH1 mutation patterns off the beaten track. Neuropathol Appl Neurobiol 2011;37:428–430.
-
(2011)
Neuropathol Appl Neurobiol
, vol.37
, pp. 428-430
-
-
Pusch, S.1
Sahm, F.2
Meyer, J.3
-
5
-
-
72049125350
-
Cancerassociated IDH1 mutations produce 2-hydroxyglutarate
-
Dang L, White DW, Gross S et al. Cancerassociated IDH1 mutations produce 2-hydroxyglutarate. Nature 2009;462:739–744.
-
(2009)
Nature
, vol.462
, pp. 739-744
-
-
Dang, L.1
White, D.W.2
Gross, S.3
-
6
-
-
73649145880
-
IDH1 mutations in gliomas: When an enzyme loses its grip
-
Frezza C, Tennant DA, Gottlieb E. IDH1 mutations in gliomas: When an enzyme loses its grip. Cancer Cell 2010;17:7–9.
-
(2010)
Cancer Cell
, vol.17
, pp. 7-9
-
-
Frezza, C.1
Tennant, D.A.2
Gottlieb, E.3
-
7
-
-
77952536841
-
IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study
-
Marcucci G, Maharry K, Wu YZ et al. IDH1 and IDH2 gene mutations identify novel molecular subsets within de novo cytogenetically normal acute myeloid leukemia: A Cancer and Leukemia Group B study. J Clin Oncol 2010;28:2348–2355.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2348-2355
-
-
Marcucci, G.1
Maharry, K.2
Wu, Y.Z.3
-
8
-
-
77950968519
-
Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation
-
Chou WC, Hou HA, Chen CY et al. Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation. Blood 2010;115:2749–2754.
-
(2010)
Blood
, vol.115
, pp. 2749-2754
-
-
Chou, W.C.1
Hou, H.A.2
Chen, C.Y.3
-
9
-
-
78149466021
-
IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders
-
Zou Y, Zeng Y, Zhang DF et al. IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. Biochem Biophys Res Commun 2010;402:378–383.
-
(2010)
Biochem Biophys Res Commun
, vol.402
, pp. 378-383
-
-
Zou, Y.1
Zeng, Y.2
Zhang, D.F.3
-
10
-
-
77149134353
-
Cancerassociated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2mutations
-
Gross S, Cairns RA, Minden MD et al. Cancerassociated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2mutations. J Exp Med 2010; 207:339–344.
-
(2010)
J Exp Med
, vol.207
, pp. 339-344
-
-
Gross, S.1
Cairns, R.A.2
Minden, M.D.3
-
11
-
-
84895821588
-
Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: A study by the Acute Leukemia French Association group
-
Janin M, Mylonas E, Saada V et al. Serum 2-hydroxyglutarate production in IDH1- and IDH2-mutated de novo acute myeloid leukemia: A study by the Acute Leukemia French Association group. J Clin Oncol 2014;32:297–305.
-
(2014)
J Clin Oncol
, vol.32
, pp. 297-305
-
-
Janin, M.1
Mylonas, E.2
Saada, V.3
-
12
-
-
33846467320
-
Li F et al.Tandem mass spectrometry measurements of creatinine inmouse plasma and urine for determining glomerular filtration rate
-
Takahashi N, Boysen G, Li F et al.Tandem mass spectrometry measurements of creatinine inmouse plasma and urine for determining glomerular filtration rate. Kidney Int 2007;71:266–271.
-
(2007)
Kidney Int
, vol.71
, pp. 266-271
-
-
Takahashi, N.1
Boysen, G.2
-
13
-
-
79952366279
-
Metabolism unhinged: IDH mutations in cancer
-
Prensner JR, Chinnaiyan AM. Metabolism unhinged: IDH mutations in cancer. Nat Med 2011; 17:291–293.
-
(2011)
Nat Med
, vol.17
, pp. 291-293
-
-
Prensner, J.R.1
Chinnaiyan, A.M.2
-
14
-
-
84898766502
-
Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma
-
Borger DR, Goyal L, Yau T et al. Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma. Clin Cancer Res 2014;20:1884–1890.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1884-1890
-
-
Borger, D.R.1
Goyal, L.2
Yau, T.3
-
15
-
-
84901927022
-
Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate
-
Fathi AT, Sadrzadeh H, Comander AH et al. Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate. The Oncologist 2014;19:602–607.
-
(2014)
The Oncologist
, vol.19
, pp. 602-607
-
-
Fathi, A.T.1
Sadrzadeh, H.2
Comander, A.H.3
-
16
-
-
78651463452
-
Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of a-ketoglutarate-dependent dioxygenases
-
Xu W, Yang H, Liu Y et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of a-ketoglutarate-dependent dioxygenases. Cancer Cell 2011;19:17–30.
-
(2011)
Cancer Cell
, vol.19
, pp. 17-30
-
-
Xu, W.1
Yang, H.2
Liu, Y.3
-
17
-
-
84859554794
-
2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlatewith IDH1/2 mutation status or tumor size
-
Capper D, Simon M, Langhans CD et al. 2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlatewith IDH1/2 mutation status or tumor size. Int J Cancer 2012; 131:766–768.
-
(2012)
Int J Cancer
, vol.131
, pp. 766-768
-
-
Capper, D.1
Simon, M.2
Langhans, C.D.3
-
19
-
-
52549111946
-
Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias
-
Hagos Y, Krick W, Braulke T et al. Organic anion transporters OAT1 and OAT4 mediate the high affinity transport of glutarate derivatives accumulating in patients with glutaric acidurias. Pflugers Arch 2008;457:223–231.
-
(2008)
Pflugers Arch
, vol.457
, pp. 223-231
-
-
Hagos, Y.1
Krick, W.2
Braulke, T.3
-
20
-
-
80055066801
-
Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3
-
Kaufhold M, Schulz K, Breljak D et al. Differential interaction of dicarboxylates with human sodium-dicarboxylate cotransporter 3 and organic anion transporters 1 and 3. Am J Physiol Renal Physiol 2011;301:F1026–F1034.
-
(2011)
Am J Physiol Renal Physiol
, vol.301
, pp. F1026-F1034
-
-
Kaufhold, M.1
Schulz, K.2
Breljak, D.3
-
21
-
-
0036801203
-
Serum to urinary sodium concentration ratio is an estimate of plasma renin activity in congestive heart failure
-
Marenzi G, Lauri G, Assanelli E et al. Serum to urinary sodium concentration ratio is an estimate of plasma renin activity in congestive heart failure. Eur J Heart Fail 2002;4:597–603.
-
(2002)
Eur J Heart Fail
, vol.4
, pp. 597-603
-
-
Marenzi, G.1
Lauri, G.2
Assanelli, E.3
-
22
-
-
73349108806
-
IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide
-
Dubbink HJ, Taal W, van Marion R et al. IDH1 mutations in low-grade astrocytomas predict survival but not response to temozolomide. Neurology 2009;73:1792–1795.
-
(2009)
Neurology
, vol.73
, pp. 1792-1795
-
-
Dubbink, H.J.1
Taal, W.2
Van Marion, R.3
-
23
-
-
70249097408
-
Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas
-
Sanson M, Marie Y, Paris S et al. Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 2009;27:4150–4154.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4150-4154
-
-
Sanson, M.1
Marie, Y.2
Paris, S.3
-
24
-
-
73349134695
-
NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
-
Wick W, Hartmann C, Engel C et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol 2009;27:5874–5880.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5874-5880
-
-
Wick, W.1
Hartmann, C.2
Engel, C.3
-
25
-
-
73349103157
-
Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network
-
Weller M, Felsberg J, Hartmann Cetal. Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: A prospective translational study of the German Glioma Network. J Clin Oncol 2009;27:5743–5750.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5743-5750
-
-
Weller, M.1
Felsberg, J.2
Cetal, H.3
-
26
-
-
84877632013
-
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
-
Rohle D, Popovici-Muller J, Palaskas N et al. An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 2013;340:626–630.
-
(2013)
Science
, vol.340
, pp. 626-630
-
-
Rohle, D.1
Popovici-Muller, J.2
Palaskas, N.3
|