-
1
-
-
77949903147
-
Epithelial barriers in homeostasis and disease
-
Marchiando, A. M., Graham, W. V. & Turner, J. R. Epithelial barriers in homeostasis and disease. Annu. Rev. Pathol. 5, 119-144 (2010).
-
(2010)
Annu. Rev. Pathol.
, vol.5
, pp. 119-144
-
-
Marchiando, A.M.1
Graham, W.V.2
Turner, J.R.3
-
3
-
-
70350509805
-
Intestinal mucosal barrier function in health and disease
-
Turner, J. R. Intestinal mucosal barrier function in health and disease. Nat. Rev. Immunol. 9, 799-809 (2009).
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 799-809
-
-
Turner, J.R.1
-
4
-
-
79953307656
-
Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice
-
Fu, J. et al. Loss of intestinal core 1-derived O-glycans causes spontaneous colitis in mice. J. Clin. Invest. 121, 1657-1666 (2011).
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1657-1666
-
-
Fu, J.1
-
5
-
-
54449083567
-
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
-
Johansson, M. E. et al. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc. Natl Acad. Sci. USA 105, 15064-15069 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 15064-15069
-
-
Johansson, M.E.1
-
6
-
-
84891736162
-
Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
-
Johansson, M. E. et al. Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis. Gut 63, 281-291 (2014).
-
(2014)
Gut
, vol.63
, pp. 281-291
-
-
Johansson, M.E.1
-
7
-
-
33745746660
-
Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection
-
Van der Sluis, M. et al. Muc2-deficient mice spontaneously develop colitis, indicating that MUC2 is critical for colonic protection. Gastroenterology 131, 117-129 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 117-129
-
-
Van Der Sluis, M.1
-
8
-
-
79951775751
-
Tight junction pore and leak pathways: A dynamic duo
-
Shen, L., Weber, C. R., Raleigh, D. R., Yu, D. & Turner, J. R. Tight junction pore and leak pathways: a dynamic duo. Annu. Rev. Physiol. 73, 283-309 (2011).
-
(2011)
Annu. Rev. Physiol.
, vol.73
, pp. 283-309
-
-
Shen, L.1
Weber, C.R.2
Raleigh, D.R.3
Yu, D.4
Turner, J.R.5
-
9
-
-
0000752197
-
Junctional complexes in various epithelia
-
Farquhar, M. & Palade, G. Junctional complexes in various epithelia. J. Cell Biol. 17, 375-412 (1963).
-
(1963)
J. Cell Biol.
, vol.17
, pp. 375-412
-
-
Farquhar, M.1
Palade, G.2
-
10
-
-
0023176321
-
Intestinal absorptive cell tight junctions are linked to cytoskeleton
-
Madara, J. L. Intestinal absorptive cell tight junctions are linked to cytoskeleton. Am. J. Physiol. 253, C171-C175 (1987).
-
(1987)
Am. J. Physiol.
, vol.253
, pp. C171-C175
-
-
Madara, J.L.1
-
11
-
-
0021228377
-
Brush border cytoskeleton and integration of cellular functions
-
Mooseker, M. S. et al. Brush border cytoskeleton and integration of cellular functions. J. Cell Biol. 99, 104s-112s (1984).
-
(1984)
J. Cell Biol.
, vol.99
, pp. 104s-112s
-
-
Mooseker, M.S.1
-
12
-
-
84901491471
-
Dynamic contacts: Rearranging adherens junctions to drive epithelial remodelling
-
Takeichi, M. Dynamic contacts: rearranging adherens junctions to drive epithelial remodelling. Nat. Rev. Mol. Cell Biol. 15, 397-410 (2014).
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 397-410
-
-
Takeichi, M.1
-
13
-
-
39849100440
-
Adherens and tight junctions: Structure, function and connections to the actin cytoskeleton
-
Hartsock, A. & Nelson, W. J. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim. Biophys. Acta 1778, 660-669 (2008).
-
(2008)
Biochim. Biophys. Acta
, vol.1778
, pp. 660-669
-
-
Hartsock, A.1
Nelson, W.J.2
-
14
-
-
28344439885
-
A-catenin is a molecular switch that binds E-cadherin-β-catenin and regulates actin-filament assembly
-
Drees, F., Pokutta, S., Yamada, S., Nelson, W. J. & Weis, W. I. a-catenin is a molecular switch that binds E-cadherin-β-catenin and regulates actin-filament assembly. Cell 123, 903-915 (2005).
-
(2005)
Cell
, vol.123
, pp. 903-915
-
-
Drees, F.1
Pokutta, S.2
Yamada, S.3
Nelson, W.J.4
Weis, W.I.5
-
15
-
-
81355138558
-
The secret life of a-catenin: Moonlighting in morphogenesis
-
Maiden, S. L. & Hardin, J. The secret life of a-catenin: moonlighting in morphogenesis. J. Cell Biol. 195, 543-552 (2011).
-
(2011)
J. Cell Biol.
, vol.195
, pp. 543-552
-
-
Maiden, S.L.1
Hardin, J.2
-
16
-
-
33846065117
-
Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells
-
Capaldo, C. T. & Macara, I. G. Depletion of E-cadherin disrupts establishment but not maintenance of cell junctions in Madin-Darby canine kidney epithelial cells. Mol. Biol. Cell 18, 189-200 (2007).
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 189-200
-
-
Capaldo, C.T.1
Macara, I.G.2
-
17
-
-
84883301688
-
ZO-1 recruitment to a-catenin -a novel mechanism for coupling the assembly of tight junctions to adherens junctions
-
Maiers, J. L., Peng, X., Fanning, A. S. & DeMali, K. A. ZO-1 recruitment to a-catenin -a novel mechanism for coupling the assembly of tight junctions to adherens junctions. J. Cell Sci. 126, 3904-3915 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 3904-3915
-
-
Maiers, J.L.1
Peng, X.2
Fanning, A.S.3
DeMali, K.A.4
-
18
-
-
0014782467
-
A fine structural analysis of intercellular junctions in the mouse liver
-
Goodenough, D. A. & Revel, J. P. A fine structural analysis of intercellular junctions in the mouse liver. J. Cell Biol. 45, 272-290 (1970).
-
(1970)
J. Cell Biol.
, vol.45
, pp. 272-290
-
-
Goodenough, D.A.1
Revel, J.P.2
-
19
-
-
0020058236
-
Evidence for the lipidic nature of tight junction strands
-
Kachar, B. & Reese, T. S. Evidence for the lipidic nature of tight junction strands. Nature 296, 464-466 (1982).
-
(1982)
Nature
, vol.296
, pp. 464-466
-
-
Kachar, B.1
Reese, T.S.2
-
20
-
-
84940894920
-
Conceptual barriers to understanding physical barriers
-
Lingaraju, A. et al. Conceptual barriers to understanding physical barriers. Semin. Cell Dev. Biol. 42, 13-21 (2015).
-
(2015)
Semin. Cell Dev. Biol.
, vol.42
, pp. 13-21
-
-
Lingaraju, A.1
-
21
-
-
0027744129
-
Occludin: A novel integral membrane protein localizing at tight junctions
-
Furuse, M. et al. Occludin: a novel integral membrane protein localizing at tight junctions. J. Cell Biol. 123, 1777-1788 (1993).
-
(1993)
J. Cell Biol.
, vol.123
, pp. 1777-1788
-
-
Furuse, M.1
-
22
-
-
0029811688
-
Alterations in cell cholesterol content modulate Ca2+-induced tight junction assembly by MDCK cells
-
Stankewich, M. C., Francis, S. A., Vu, Q. U., Schneeberger, E. E. & Lynch, R. D. Alterations in cell cholesterol content modulate Ca2+-induced tight junction assembly by MDCK cells. Lipids 31, 817-828 (1996).
-
(1996)
Lipids
, vol.31
, pp. 817-828
-
-
Stankewich, M.C.1
Francis, S.A.2
Vu, Q.U.3
Schneeberger, E.E.4
Lynch, R.D.5
-
23
-
-
0032840311
-
Rapid reduction of MDCK cell cholesterol by methyl-cyclodextrin alters steady state transepithelial electrical resistance
-
Francis, S. A. et al. Rapid reduction of MDCK cell cholesterol by methyl-cyclodextrin alters steady state transepithelial electrical resistance. Eur. J. Cell Biol. 78, 473-484 (1999).
-
(1999)
Eur. J. Cell Biol.
, vol.78
, pp. 473-484
-
-
Francis, S.A.1
-
24
-
-
33745193296
-
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
-
Shen, L. et al. Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure. J. Cell Sci. 119, 2095-2106 (2006).
-
(2006)
J. Cell Sci.
, vol.119
, pp. 2095-2106
-
-
Shen, L.1
-
25
-
-
33645963995
-
Claudins and epithelial paracellular transport
-
Van Itallie, C. M. & Anderson, J. M. Claudins and epithelial paracellular transport. Annu. Rev. Physiol. 68, 403-429 (2006).
-
(2006)
Annu. Rev. Physiol.
, vol.68
, pp. 403-429
-
-
Van Itallie, C.M.1
Anderson, J.M.2
-
26
-
-
0035897412
-
Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney i cells
-
Furuse, M., Furuse, K., Sasaki, H. & Tsukita, S. Conversion of zonulae occludentes from tight to leaky strand type by introducing claudin-2 into Madin-Darby canine kidney I cells. J. Cell Biol. 153, 263-272 (2001).
-
(2001)
J. Cell Biol.
, vol.153
, pp. 263-272
-
-
Furuse, M.1
Furuse, K.2
Sasaki, H.3
Tsukita, S.4
-
27
-
-
0037115724
-
Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells
-
Amasheh, S. et al. Claudin-2 expression induces cation-selective channels in tight junctions of epithelial cells. J. Cell Sci. 115, 4969-4976 (2002).
-
(2002)
J. Cell Sci.
, vol.115
, pp. 4969-4976
-
-
Amasheh, S.1
-
28
-
-
84957922490
-
Claudin-2-dependent paracellular channels are dynamically gated
-
Weber, C. R. et al. Claudin-2-dependent paracellular channels are dynamically gated. eLife 4, e09906 (2015).
-
(2015)
ELife
, vol.4
, pp. e09906
-
-
Weber, C.R.1
-
29
-
-
77950588683
-
Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity
-
Weber, C. R. et al. Epithelial myosin light chain kinase activation induces mucosal interleukin-13 expression to alter tight junction ion selectivity. J. Biol. Chem. 285, 12037-12046 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 12037-12046
-
-
Weber, C.R.1
-
30
-
-
79956202699
-
Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function
-
Raleigh, D. R. et al. Occludin S408 phosphorylation regulates tight junction protein interactions and barrier function. J. Cell Biol. 193, 565-582 (2011).
-
(2011)
J. Cell Biol.
, vol.193
, pp. 565-582
-
-
Raleigh, D.R.1
-
31
-
-
84881534032
-
Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition
-
Wada, M., Tamura, A., Takahashi, N. & Tsukita, S. Loss of claudins 2 and 15 from mice causes defects in paracellular Na+ flow and nutrient transport in gut and leads to death from malnutrition. Gastroenterology 144, 369-380 (2013).
-
(2013)
Gastroenterology
, vol.144
, pp. 369-380
-
-
Wada, M.1
Tamura, A.2
Takahashi, N.3
Tsukita, S.4
-
32
-
-
79952286129
-
Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine
-
Tamura, A. et al. Loss of claudin-15, but not claudin-2, causes Na+ deficiency and glucose malabsorption in mouse small intestine. Gastroenterology 140, 913-923 (2011).
-
(2011)
Gastroenterology
, vol.140
, pp. 913-923
-
-
Tamura, A.1
-
33
-
-
84912106825
-
The role of molecular remodeling in differential regulation of tight junction permeability
-
Turner, J. R., Buschmann, M. M., Romero-Calvo, I., Sailer, A. & Shen, L. The role of molecular remodeling in differential regulation of tight junction permeability. Semin. Cell Dev. Biol. 36, 204-212 (2014).
-
(2014)
Semin. Cell Dev. Biol.
, vol.36
, pp. 204-212
-
-
Turner, J.R.1
Buschmann, M.M.2
Romero-Calvo, I.3
Sailer, A.4
Shen, L.5
-
34
-
-
77950663681
-
Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions
-
Raleigh, D. R. et al. Tight junction-associated MARVEL proteins marveld3, tricellulin, and occludin have distinct but overlapping functions. Mol. Biol. Cell 21, 1200-1213 (2010).
-
(2010)
Mol. Biol. Cell
, vol.21
, pp. 1200-1213
-
-
Raleigh, D.R.1
-
35
-
-
0028110309
-
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions
-
Furuse, M. et al. Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctions. J. Cell Biol. 127, 1617-1626 (1994).
-
(1994)
J. Cell Biol.
, vol.127
, pp. 1617-1626
-
-
Furuse, M.1
-
36
-
-
84876075035
-
In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization
-
Cording, J. et al. In tight junctions, claudins regulate the interactions between occludin, tricellulin and marvelD3, which, inversely, modulate claudin oligomerization. J. Cell Sci. 126, 554-564 (2013).
-
(2013)
J. Cell Sci.
, vol.126
, pp. 554-564
-
-
Cording, J.1
-
37
-
-
67249084776
-
Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions
-
Fanning, A. S. & Anderson, J. M. Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctions. Ann. N. Y. Acad. Sci. 1165, 113-120 (2009).
-
(2009)
Ann. N. Y. Acad. Sci.
, vol.1165
, pp. 113-120
-
-
Fanning, A.S.1
Anderson, J.M.2
-
38
-
-
0029095287
-
Zonula occludens (ZO)-1 and ZO-2: Membrane-associated guanylate kinase homologues (MAGuKs) of the tight junction
-
Anderson, J. M., Fanning, A. S., Lapierre, L. & Van Itallie, C. M. Zonula occludens (ZO)-1 and ZO-2: membrane-associated guanylate kinase homologues (MAGuKs) of the tight junction. Biochem. Soc. Trans. 23, 470-475 (1995).
-
(1995)
Biochem. Soc. Trans.
, vol.23
, pp. 470-475
-
-
Anderson, J.M.1
Fanning, A.S.2
Lapierre, L.3
Van Itallie, C.M.4
-
39
-
-
48649096603
-
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells
-
Katsuno, T. et al. Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cells. Mol. Biol. Cell 19, 2465-2475 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 2465-2475
-
-
Katsuno, T.1
-
40
-
-
40749084863
-
Early embryonic lethality of mice lacking ZO-2, but not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development
-
Xu, J. et al. Early embryonic lethality of mice lacking ZO-2, but not ZO-3, reveals critical and nonredundant roles for individual zonula occludens proteins in mammalian development. Mol. Cell. Biol. 28, 1669-1678 (2008).
-
(2008)
Mol. Cell. Biol.
, vol.28
, pp. 1669-1678
-
-
Xu, J.1
-
41
-
-
0037994064
-
Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT
-
Carlton, V. E. et al. Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Nat. Genet. 34, 91-96 (2003).
-
(2003)
Nat. Genet.
, vol.34
, pp. 91-96
-
-
Carlton, V.E.1
-
42
-
-
84898057518
-
Mutations in TJP2 cause progressive cholestatic liver disease
-
Sambrotta, M. et al. Mutations in TJP2 cause progressive cholestatic liver disease. Nat. Genet. 46, 326-328 (2014).
-
(2014)
Nat. Genet.
, vol.46
, pp. 326-328
-
-
Sambrotta, M.1
-
43
-
-
84908279831
-
Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice
-
Matsumoto, K. et al. Claudin 2 deficiency reduces bile flow and increases susceptibility to cholesterol gallstone disease in mice. Gastroenterology 147, 1134-1145.e10 (2014).
-
(2014)
Gastroenterology
, vol.147
, pp. 1134-1134e10
-
-
Matsumoto, K.1
-
44
-
-
84928969190
-
Hepatic injury in nonalcoholic steatohepatitis contributes to altered intestinal permeability
-
Luther, J. et al. Hepatic injury in nonalcoholic steatohepatitis contributes to altered intestinal permeability. Cell. Mol. Gastroenterol. Hepatol. 1, 222-232 (2015).
-
(2015)
Cell. Mol. Gastroenterol. Hepatol.
, vol.1
, pp. 222-232
-
-
Luther, J.1
-
46
-
-
70349317350
-
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton
-
Van Itallie, C. M., Fanning, A. S., Bridges, A. & Anderson, J. M. ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeleton. Mol. Biol. Cell 20, 3930-3940 (2009).
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 3930-3940
-
-
Van Itallie, C.M.1
Fanning, A.S.2
Bridges, A.3
Anderson, J.M.4
-
47
-
-
84932608065
-
Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease
-
Nalle, S. C. & Turner, J. R. Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease. Mucosal Immunol. 8, 720-730 (2015).
-
(2015)
Mucosal Immunol.
, vol.8
, pp. 720-730
-
-
Nalle, S.C.1
Turner, J.R.2
-
48
-
-
84880611949
-
TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosismediated barrier loss and experimental colitis
-
Su, L. et al. TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosismediated barrier loss and experimental colitis. Gastroenterology 145, 407-415 (2013).
-
(2013)
Gastroenterology
, vol.145
, pp. 407-415
-
-
Su, L.1
-
49
-
-
84928963727
-
Experimental models of inflammatory bowel diseases
-
Kiesler, P., Fuss, I. J. & Strober, W. Experimental models of inflammatory bowel diseases. Cell. Mol. Gastroenterol. Hepatol. 1, 154-170 (2015).
-
(2015)
Cell. Mol. Gastroenterol. Hepatol.
, vol.1
, pp. 154-170
-
-
Kiesler, P.1
Fuss, I.J.2
Strober, W.3
-
50
-
-
0035210487
-
Epithelial barrier defects in ulcerative colitis: Characterization and quantification by electrophysiological imaging
-
Gitter, A. H., Wullstein, F., Fromm, M. & Schulzke, J. D. Epithelial barrier defects in ulcerative colitis: characterization and quantification by electrophysiological imaging. Gastroenterology 121, 1320-1328 (2001).
-
(2001)
Gastroenterology
, vol.121
, pp. 1320-1328
-
-
Gitter, A.H.1
Wullstein, F.2
Fromm, M.3
Schulzke, J.D.4
-
51
-
-
77957223906
-
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells
-
Snippert, H. J. et al. Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells. Cell 143, 134-144 (2010).
-
(2010)
Cell
, vol.143
, pp. 134-144
-
-
Snippert, H.J.1
-
52
-
-
67651159312
-
Stem cells, selfrenewal, and differentiation in the intestinal epithelium
-
van der Flier, L. G. & Clevers, H. Stem cells, selfrenewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71, 241-260 (2009).
-
(2009)
Annu. Rev. Physiol.
, vol.71
, pp. 241-260
-
-
Van Der Flier, L.G.1
Clevers, H.2
-
53
-
-
84975748266
-
Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche
-
Aoki, R. et al. Foxl1-expressing mesenchymal cells constitute the intestinal stem cell niche. Cell. Mol. Gastroenterol. Hepatol. 2, 175-188 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 175-188
-
-
Aoki, R.1
-
54
-
-
17144428522
-
Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure
-
Russo, J. M. et al. Distinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure. Gastroenterology 128, 987-1001 (2005).
-
(2005)
Gastroenterology
, vol.128
, pp. 987-1001
-
-
Russo, J.M.1
-
55
-
-
79953174256
-
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding
-
Marchiando, A. M. et al. The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding. Gastroenterology 140, 1208-1218.e2 (2011).
-
(2011)
Gastroenterology
, vol.140
, pp. 1208-1208e2
-
-
Marchiando, A.M.1
-
56
-
-
0035960736
-
An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosindependent mechanism
-
Rosenblatt, J., Raff, M. C. & Cramer, L. P. An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin-and myosindependent mechanism. Curr. Biol. 11, 1847-1857 (2001).
-
(2001)
Curr. Biol.
, vol.11
, pp. 1847-1857
-
-
Rosenblatt, J.1
Raff, M.C.2
Cramer, L.P.3
-
57
-
-
0023510866
-
Structural basis for physiological regulation of paracellular pathways in intestinal epithelia
-
Madara, J. L. & Pappenheimer, J. R. Structural basis for physiological regulation of paracellular pathways in intestinal epithelia. J. Membr. Biol. 100, 149-164 (1987).
-
(1987)
J. Membr. Biol.
, vol.100
, pp. 149-164
-
-
Madara, J.L.1
Pappenheimer, J.R.2
-
58
-
-
0023520885
-
Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters
-
Pappenheimer, J. R. Physiological regulation of transepithelial impedance in the intestinal mucosa of rats and hamsters. J. Membr. Biol. 100, 137-148 (1987).
-
(1987)
J. Membr. Biol.
, vol.100
, pp. 137-148
-
-
Pappenheimer, J.R.1
-
59
-
-
0023521841
-
Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat
-
Pappenheimer, J. R. & Reiss, K. Z. Contribution of solvent drag through intercellular junctions to absorption of nutrients by the small intestine of the rat. J. Membr. Biol. 100, 123-136 (1987).
-
(1987)
J. Membr. Biol.
, vol.100
, pp. 123-136
-
-
Pappenheimer, J.R.1
Reiss, K.Z.2
-
60
-
-
0030669302
-
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation
-
Turner, J. R. et al. Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation. Am. J. Physiol. 273, C1378-C1385 (1997).
-
(1997)
Am. J. Physiol.
, vol.273
, pp. C1378-C1385
-
-
Turner, J.R.1
-
61
-
-
0034733881
-
Show me the pathway! Regulation of paracellular permeability by Na+-glucose cotransport
-
Turner, J. R. Show me the pathway! Regulation of paracellular permeability by Na+-glucose cotransport. Adv. Drug Deliv. Rev. 41, 265-281 (2000).
-
(2000)
Adv. Drug Deliv. Rev.
, vol.41
, pp. 265-281
-
-
Turner, J.R.1
-
62
-
-
0024525147
-
Intestinal glucose transport using perfused rat jejunum in vivo: Model analysis and derivation of corrected kinetic constants
-
Meddings, J. B. & Westergaard, H. Intestinal glucose transport using perfused rat jejunum in vivo: model analysis and derivation of corrected kinetic constants. Clin. Sci. (Lond.) 76, 403-413 (1989).
-
(1989)
Clin. Sci. (Lond.)
, vol.76
, pp. 403-413
-
-
Meddings, J.B.1
Westergaard, H.2
-
63
-
-
0027763397
-
Luminal nutrients alter tight-junction permeability in the rat jejunum: An in vivo perfusion model
-
Sadowski, D. C. & Meddings, J. B. Luminal nutrients alter tight-junction permeability in the rat jejunum: an in vivo perfusion model. Can. J. Physiol. Pharmacol. 71, 835-839 (1993).
-
(1993)
Can. J. Physiol. Pharmacol.
, vol.71
, pp. 835-839
-
-
Sadowski, D.C.1
Meddings, J.B.2
-
64
-
-
0034527745
-
Noninvasive in vivo analysis of human small intestinal paracellular absorption: Regulation by Na+-glucose cotransport
-
Turner, J. R., Cohen, D. E., Mrsny, R. J. & Madara, J. L. Noninvasive in vivo analysis of human small intestinal paracellular absorption: regulation by Na+-glucose cotransport. Dig. Dis. Sci. 45, 2122-2126 (2000).
-
(2000)
Dig. Dis. Sci.
, vol.45
, pp. 2122-2126
-
-
Turner, J.R.1
Cohen, D.E.2
Mrsny, R.J.3
Madara, J.L.4
-
65
-
-
23244455992
-
Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution
-
Heller, F. et al. Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution. Gastroenterology 129, 550-564 (2005).
-
(2005)
Gastroenterology
, vol.129
, pp. 550-564
-
-
Heller, F.1
-
66
-
-
80052400212
-
Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium
-
Suzuki, T., Yoshinaga, N. & Tanabe, S. Interleukin-6 (IL-6) regulates claudin-2 expression and tight junction permeability in intestinal epithelium. J. Biol. Chem. 286, 31263-31271 (2011).
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 31263-31271
-
-
Suzuki, T.1
Yoshinaga, N.2
Tanabe, S.3
-
67
-
-
36849042673
-
Opposing regulation of the tight junction protein claudin-2 by interferon- and interleukin-4
-
Wisner, D. M., Harris, L. R. III, Green, C. L. & Poritz, L. S. Opposing regulation of the tight junction protein claudin-2 by interferon- and interleukin-4. J. Surg. Res. 144, 1-7 (2008).
-
(2008)
J. Surg. Res.
, vol.144
, pp. 1-7
-
-
Wisner, D.M.1
Harris, L.R.2
Green, C.L.3
Poritz, L.S.4
-
68
-
-
77954655235
-
TNFa up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling
-
Mankertz, J. et al. TNFa up-regulates claudin-2 expression in epithelial HT-29/B6 cells via phosphatidylinositol-3-kinase signaling. Cell Tissue Res. 336, 67-77 (2009).
-
(2009)
Cell Tissue Res.
, vol.336
, pp. 67-77
-
-
Mankertz, J.1
-
69
-
-
84902653958
-
TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells
-
Gerlach, K. et al. TH9 cells that express the transcription factor PU.1 drive T cell-mediated colitis via IL-9 receptor signaling in intestinal epithelial cells. Nat. Immunol. 15, 676-686 (2014).
-
(2014)
Nat. Immunol.
, vol.15
, pp. 676-686
-
-
Gerlach, K.1
-
70
-
-
33845995125
-
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohns disease
-
Zeissig, S. et al. Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohns disease. Gut 56, 61-72 (2007).
-
(2007)
Gut
, vol.56
, pp. 61-72
-
-
Zeissig, S.1
-
71
-
-
27744551342
-
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
-
Prasad, S. et al. Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells. Lab. Invest. 85, 1139-1162 (2005).
-
(2005)
Lab. Invest.
, vol.85
, pp. 1139-1162
-
-
Prasad, S.1
-
72
-
-
60549090106
-
Molecular basis for cation selectivity in claudin-2-based paracellular pores: Identification of an electrostatic interaction site
-
Yu, A. S. et al. Molecular basis for cation selectivity in claudin-2-based paracellular pores: identification of an electrostatic interaction site. J. Gen. Physiol. 133, 111-127 (2009).
-
(2009)
J. Gen. Physiol.
, vol.133
, pp. 111-127
-
-
Yu, A.S.1
-
73
-
-
84881256884
-
Conserved aromatic residue confers cation selectivity in claudin-2 and claudin-10b
-
Li, J., Zhuo, M., Pei, L. & Yu, A. S. Conserved aromatic residue confers cation selectivity in claudin-2 and claudin-10b. J. Biol. Chem. 288, 22790-22797 (2013).
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 22790-22797
-
-
Li, J.1
Zhuo, M.2
Pei, L.3
Yu, A.S.4
-
74
-
-
84896797690
-
Comprehensive cysteine-scanning mutagenesis reveals claudin-2 pore-lining residues with different intrapore locations
-
Li, J., Zhuo, M., Pei, L., Rajagopal, M. & Yu, A. S. Comprehensive cysteine-scanning mutagenesis reveals claudin-2 pore-lining residues with different intrapore locations. J. Biol. Chem. 289, 6475-6484 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 6475-6484
-
-
Li, J.1
Zhuo, M.2
Pei, L.3
Rajagopal, M.4
Yu, A.S.5
-
75
-
-
0021251275
-
Partitioning of paracellular conductance along the ileal crypt-villus axis: A hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships
-
Marcial, M. A., Carlson, S. L. & Madara, J. L. Partitioning of paracellular conductance along the ileal crypt-villus axis: a hypothesis based on structural analysis with detailed consideration of tight junction structure-function relationships. J. Membr. Biol. 80, 59-70 (1984).
-
(1984)
J. Membr. Biol.
, vol.80
, pp. 59-70
-
-
Marcial, M.A.1
Carlson, S.L.2
Madara, J.L.3
-
76
-
-
0033774567
-
Permeability of the rat small intestinal epithelium along the villus-crypt axis: Effects of glucose transport
-
Fihn, B. M., Sjoqvist, A. & Jodal, M. Permeability of the rat small intestinal epithelium along the villus-crypt axis: effects of glucose transport. Gastroenterology 119, 1029-1036 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 1029-1036
-
-
Fihn, B.M.1
Sjoqvist, A.2
Jodal, M.3
-
77
-
-
0022877339
-
Maturation of tight junctions in Guinea-pig cecal epithelium
-
Mora-Galindo, J. Maturation of tight junctions in guinea-pig cecal epithelium. Cell Tissue Res. 246, 169-175 (1986).
-
(1986)
Cell Tissue Res.
, vol.246
, pp. 169-175
-
-
Mora-Galindo, J.1
-
78
-
-
0036678630
-
Anti-tumor necrosis factor treatment restores the gut barrier in Crohns disease
-
Suenaert, P. et al. Anti-tumor necrosis factor treatment restores the gut barrier in Crohns disease. Am. J. Gastroenterol. 97, 2000-2004 (2002).
-
(2002)
Am. J. Gastroenterol.
, vol.97
, pp. 2000-2004
-
-
Suenaert, P.1
-
79
-
-
0032923705
-
Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohns ileocolitis
-
Baert, F. J. et al. Tumor necrosis factor alpha antibody (infliximab) therapy profoundly down-regulates the inflammation in Crohns ileocolitis. Gastroenterology 116, 22-28 (1999).
-
(1999)
Gastroenterology
, vol.116
, pp. 22-28
-
-
Baert, F.J.1
-
80
-
-
0036305854
-
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease
-
Zolotarevsky, Y. et al. A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease. Gastroenterology 123, 163-172 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 163-172
-
-
Zolotarevsky, Y.1
-
81
-
-
13244298599
-
Interferon and tumor necrosis factor-a synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression
-
Wang, F. et al. Interferon and tumor necrosis factor-a synergize to induce intestinal epithelial barrier dysfunction by up-regulating myosin light chain kinase expression. Am. J. Pathol. 166, 409-419 (2005).
-
(2005)
Am. J. Pathol.
, vol.166
, pp. 409-419
-
-
Wang, F.1
-
82
-
-
33749428028
-
Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo
-
Clayburgh, D. R., Musch, M. W., Leitges, M., Fu, Y. X. & Turner, J. R. Coordinated epithelial NHE3 inhibition and barrier dysfunction are required for TNF-mediated diarrhea in vivo. J. Clin. Invest. 116, 2682-2694 (2006).
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 2682-2694
-
-
Clayburgh, D.R.1
Musch, M.W.2
Leitges, M.3
Fu, Y.X.4
Turner, J.R.5
-
83
-
-
33749466490
-
IFN-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction
-
Wang, F. et al. IFN-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology 131, 1153-1163 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 1153-1163
-
-
Wang, F.1
-
84
-
-
26444577545
-
Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo
-
Clayburgh, D. R. et al. Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivo. J. Clin. Invest. 115, 2702-2715 (2005).
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 2702-2715
-
-
Clayburgh, D.R.1
-
85
-
-
33748747620
-
Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter
-
Graham, W. V. et al. Tumor necrosis factor-induced long myosin light chain kinase transcription is regulated by differentiation-dependent signaling events. Characterization of the human long myosin light chain kinase promoter. J. Biol. Chem. 281, 26205-26215 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26205-26215
-
-
Graham, W.V.1
-
86
-
-
58649090901
-
Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis
-
Su, L. et al. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 136, 551-563 (2009).
-
(2009)
Gastroenterology
, vol.136
, pp. 551-563
-
-
Su, L.1
-
87
-
-
77950585581
-
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo
-
Marchiando, A. M. et al. Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivo. J. Cell Biol. 189, 111-126 (2010).
-
(2010)
J. Cell Biol.
, vol.189
, pp. 111-126
-
-
Marchiando, A.M.1
-
88
-
-
84884738779
-
Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux
-
Buschmann, M. M. et al. Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular flux. Mol. Biol. Cell 24, 3056-3068 (2013).
-
(2013)
Mol. Biol. Cell
, vol.24
, pp. 3056-3068
-
-
Buschmann, M.M.1
-
89
-
-
77955992054
-
Occludin is required for cytokine-induced regulation of tight junction barriers
-
Van Itallie, C. M., Fanning, A. S., Holmes, J. & Anderson, J. M. Occludin is required for cytokine-induced regulation of tight junction barriers. J. Cell Sci. 123, 2844-2852 (2010).
-
(2010)
J. Cell Sci.
, vol.123
, pp. 2844-2852
-
-
Van Itallie, C.M.1
Fanning, A.S.2
Holmes, J.3
Anderson, J.M.4
-
90
-
-
77953020085
-
Tricellulin forms homomeric and heteromeric tight junctional complexes
-
Westphal, J. K. et al. Tricellulin forms homomeric and heteromeric tight junctional complexes. Cell. Mol. Life Sci. 67, 2057-2068 (2010).
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 2057-2068
-
-
Westphal, J.K.1
-
91
-
-
69949110857
-
Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability
-
Krug, S. M. et al. Tricellulin forms a barrier to macromolecules in tricellular tight junctions without affecting ion permeability. Mol. Biol. Cell 20, 3713-3724 (2009).
-
(2009)
Mol. Biol. Cell
, vol.20
, pp. 3713-3724
-
-
Krug, S.M.1
-
92
-
-
58149279832
-
Loss of occludin affects tricellular localization of tricellulin
-
Ikenouchi, J., Sasaki, H., Tsukita, S., Furuse, M. & Tsukita, S. Loss of occludin affects tricellular localization of tricellulin. Mol. Biol. Cell 19, 4687-4693 (2008).
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4687-4693
-
-
Ikenouchi, J.1
Sasaki, H.2
Tsukita, S.3
Furuse, M.4
Tsukita, S.5
-
93
-
-
77957748045
-
C-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells
-
Kojima, T. et al. c-Jun N-terminal kinase is largely involved in the regulation of tricellular tight junctions via tricellulin in human pancreatic duct epithelial cells. J. Cell. Physiol. 225, 720-733 (2010).
-
(2010)
J. Cell. Physiol.
, vol.225
, pp. 720-733
-
-
Kojima, T.1
-
94
-
-
84883509402
-
Tricellulin deficiency affects tight junction architecture and cochlear hair cells
-
Nayak, G. et al. Tricellulin deficiency affects tight junction architecture and cochlear hair cells. J. Clin. Invest. 123, 4036-4049 (2013).
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 4036-4049
-
-
Nayak, G.1
-
95
-
-
33845190613
-
Tricellulin is a tight-junction protein necessary for hearing
-
Riazuddin, S. et al. Tricellulin is a tight-junction protein necessary for hearing. Am. J. Hum. Genet. 79, 1040-1051 (2006).
-
(2006)
Am. J. Hum. Genet.
, vol.79
, pp. 1040-1051
-
-
Riazuddin, S.1
-
96
-
-
38949172779
-
Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families
-
Chishti, M. S. et al. Splice-site mutations in the TRIC gene underlie autosomal recessive nonsyndromic hearing impairment in Pakistani families. J. Hum. Genet. 53, 101-105 (2008).
-
(2008)
J. Hum. Genet.
, vol.53
, pp. 101-105
-
-
Chishti, M.S.1
-
97
-
-
84979036476
-
Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells
-
Kitajiri, S. I. et al. Deafness in occludin-deficient mice with dislocation of tricellulin and progressive apoptosis of the hair cells. Biol. Open 3, 759-766 (2014).
-
(2014)
Biol. Open
, vol.3
, pp. 759-766
-
-
Kitajiri, S.I.1
-
98
-
-
0033635344
-
Complex phenotype of mice lacking occludin, a component of tight junction strands
-
Saitou, M. et al. Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol. Biol. Cell 11, 4131-4142 (2000).
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 4131-4142
-
-
Saitou, M.1
-
99
-
-
17444392533
-
Epithelial transport and barrier function in occludin-deficient mice
-
Schulzke, J. D. et al. Epithelial transport and barrier function in occludin-deficient mice. Biochim. Biophys. Acta 1669, 34-42 (2005).
-
(2005)
Biochim. Biophys. Acta
, vol.1669
, pp. 34-42
-
-
Schulzke, J.D.1
-
100
-
-
33645049332
-
The primary defect in experimental ileitis originates from a nonhematopoietic source
-
Olson, T. S. et al. The primary defect in experimental ileitis originates from a nonhematopoietic source. J. Exp. Med. 203, 541-552 (2006).
-
(2006)
J. Exp. Med.
, vol.203
, pp. 541-552
-
-
Olson, T.S.1
-
101
-
-
59849104578
-
Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: Effects of age, duration of illness and the translocation of LPS from gram-negative bacteria
-
Maes, M. & Leunis, J. C. Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria. Neuro Endocrinol. Lett. 29, 902-910 (2008).
-
(2008)
Neuro Endocrinol. Lett.
, vol.29
, pp. 902-910
-
-
Maes, M.1
Leunis, J.C.2
-
102
-
-
84956911098
-
Leaky gut -concept or clinical entity? Curr
-
Quigley, E. M. Leaky gut -concept or clinical entity? Curr. Opin. Gastroenterol. 32, 74-79 (2016).
-
(2016)
Opin. Gastroenterol.
, vol.32
, pp. 74-79
-
-
Quigley, E.M.1
-
103
-
-
84882797836
-
Intestinal permeability defects: Is it time to treat? Clin
-
Odenwald, M. A. & Turner, J. R. Intestinal permeability defects: is it time to treat? Clin. Gastroenterol. Hepatol. 11, 1075-1083 (2013).
-
(2013)
Gastroenterol. Hepatol.
, vol.11
, pp. 1075-1083
-
-
Odenwald, M.A.1
Turner, J.R.2
-
104
-
-
84951296372
-
Enterohemorrhagic Escherichia coli reduces mucus and intermicrovillar bridges in human stem cell-derived colonoids
-
In, J. et al. Enterohemorrhagic Escherichia coli reduces mucus and intermicrovillar bridges in human stem cell-derived colonoids. Cell. Mol. Gastroenterol. Hepatol. 2, 48-62.e3 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 48-48e3
-
-
In, J.1
-
105
-
-
0030775148
-
Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability
-
Yuhan, R., Koutsouris, A., Savkovic, S. D. & Hecht, G. Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeability. Gastroenterology 113, 1873-1882 (1997).
-
(1997)
Gastroenterology
, vol.113
, pp. 1873-1882
-
-
Yuhan, R.1
Koutsouris, A.2
Savkovic, S.D.3
Hecht, G.4
-
106
-
-
0033523773
-
Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: Evidence for direct involvement of claudins in tight junction barrier
-
Sonoda, N. et al. Clostridium perfringens enterotoxin fragment removes specific claudins from tight junction strands: evidence for direct involvement of claudins in tight junction barrier. J. Cell Biol. 147, 195-204 (1999).
-
(1999)
J. Cell Biol.
, vol.147
, pp. 195-204
-
-
Sonoda, N.1
-
107
-
-
84922879446
-
Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin
-
Saitoh, Y. et al. Tight junctions. Structural insight into tight junction disassembly by Clostridium perfringens enterotoxin. Science 347, 775-778 (2015).
-
(2015)
Science
, vol.347
, pp. 775-778
-
-
Saitoh, Y.1
-
108
-
-
0026577118
-
Clostridium difficile toxin B disrupts the barrier function of T84 monolayers
-
Hecht, G., Koutsouris, A., Pothoulakis, C., LaMont, J. T. & Madara, J. L. Clostridium difficile toxin B disrupts the barrier function of T84 monolayers. Gastroenterology 102, 416-423 (1992).
-
(1992)
Gastroenterology
, vol.102
, pp. 416-423
-
-
Hecht, G.1
Koutsouris, A.2
Pothoulakis, C.3
LaMont, J.T.4
Madara, J.L.5
-
109
-
-
0029054398
-
Glucosylation of Rho proteins by Clostridium difficile toxin B
-
Just, I. et al. Glucosylation of Rho proteins by Clostridium difficile toxin B. Nature 375, 500-503 (1995).
-
(1995)
Nature
, vol.375
, pp. 500-503
-
-
Just, I.1
-
110
-
-
0024267211
-
Crohns disease -a permeability disorder of the tight junction?
-
Hollander, D. Crohns disease -a permeability disorder of the tight junction? Gut 29, 1621-1624 (1988).
-
(1988)
Gut
, vol.29
, pp. 1621-1624
-
-
Hollander, D.1
-
111
-
-
0019996563
-
Intestinal permeability in children with Crohns disease and coeliac disease
-
Pearson, A. D., Eastham, E. J., Laker, M. F., Craft, A. W. & Nelson, R. Intestinal permeability in children with Crohns disease and coeliac disease. Br. Med. J. (Clin. Res. Ed.) 285, 20-21 (1982).
-
(1982)
Br. Med. J. (Clin. Res. Ed.)
, vol.285
, pp. 20-21
-
-
Pearson, A.D.1
Eastham, E.J.2
Laker, M.F.3
Craft, A.W.4
Nelson, R.5
-
112
-
-
0020643629
-
Abnormal small intestinal permeability to sugars in patients with Crohns disease of the terminal ileum and colon
-
Ukabam, S. O., Clamp, J. R. & Cooper, B. T. Abnormal small intestinal permeability to sugars in patients with Crohns disease of the terminal ileum and colon. Digestion 27, 70-74 (1983).
-
(1983)
Digestion
, vol.27
, pp. 70-74
-
-
Ukabam, S.O.1
Clamp, J.R.2
Cooper, B.T.3
-
113
-
-
0032958705
-
Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis
-
Schmitz, H. et al. Altered tight junction structure contributes to the impaired epithelial barrier function in ulcerative colitis. Gastroenterology 116, 301-309 (1999).
-
(1999)
Gastroenterology
, vol.116
, pp. 301-309
-
-
Schmitz, H.1
-
114
-
-
52649123158
-
Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation
-
Weber, C. R., Nalle, S. C., Tretiakova, M., Rubin, D. T. & Turner, J. R. Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation. Lab. Invest. 88, 1110-1120 (2008).
-
(2008)
Lab. Invest.
, vol.88
, pp. 1110-1120
-
-
Weber, C.R.1
Nalle, S.C.2
Tretiakova, M.3
Rubin, D.T.4
Turner, J.R.5
-
115
-
-
30944443377
-
Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease
-
Blair, S. A., Kane, S. V., Clayburgh, D. R. & Turner, J. R. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab. Invest. 86, 191-201 (2006).
-
(2006)
Lab. Invest.
, vol.86
, pp. 191-201
-
-
Blair, S.A.1
Kane, S.V.2
Clayburgh, D.R.3
Turner, J.R.4
-
116
-
-
0027217379
-
Intestinal permeability and the prediction of relapse in Crohns disease
-
Wyatt, J., Vogelsang, H., Hubl, W., Waldhoer, T. & Lochs, H. Intestinal permeability and the prediction of relapse in Crohns disease. Lancet 341, 1437-1439 (1993).
-
(1993)
Lancet
, vol.341
, pp. 1437-1439
-
-
Wyatt, J.1
Vogelsang, H.2
Hubl, W.3
Waldhoer, T.4
Lochs, H.5
-
117
-
-
0032871326
-
Intestinal permeability test as a predictor of clinical course in Crohns disease
-
DInca, R. et al. Intestinal permeability test as a predictor of clinical course in Crohns disease. Am. J. Gastroenterol. 94, 2956-2960 (1999).
-
(1999)
Am. J. Gastroenterol.
, vol.94
, pp. 2956-2960
-
-
Dinca, R.1
-
118
-
-
0034234796
-
Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease
-
Tibble, J. A., Sigthorsson, G., Bridger, S., Fagerhol, M. K. & Bjarnason, I. Surrogate markers of intestinal inflammation are predictive of relapse in patients with inflammatory bowel disease. Gastroenterology 119, 15-22 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 15-22
-
-
Tibble, J.A.1
Sigthorsson, G.2
Bridger, S.3
Fagerhol, M.K.4
Bjarnason, I.5
-
119
-
-
84862880940
-
Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease
-
Kiesslich, R. et al. Local barrier dysfunction identified by confocal laser endomicroscopy predicts relapse in inflammatory bowel disease. Gut 61, 1146-1153 (2012).
-
(2012)
Gut
, vol.61
, pp. 1146-1153
-
-
Kiesslich, R.1
-
120
-
-
0025286406
-
Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: Physiological rearrangement of tight junctions
-
Madara, J. L. Maintenance of the macromolecular barrier at cell extrusion sites in intestinal epithelium: physiological rearrangement of tight junctions. J. Membr. Biol. 116, 177-184 (1990).
-
(1990)
J. Membr. Biol.
, vol.116
, pp. 177-184
-
-
Madara, J.L.1
-
121
-
-
0022970442
-
Increased intestinal permeability in patients with Crohns disease and their relatives. A possible etiologic factor
-
Hollander, D. et al. Increased intestinal permeability in patients with Crohns disease and their relatives. A possible etiologic factor. Ann. Intern. Med. 105, 883-885 (1986).
-
(1986)
Ann. Intern. Med.
, vol.105
, pp. 883-885
-
-
Hollander, D.1
-
122
-
-
84992648249
-
A disease-associated microbial and metabolomics state in relatives of pediatric inflammatory bowel disease patients
-
Jacobs, J. P. et al. A disease-associated microbial and metabolomics state in relatives of pediatric inflammatory bowel disease patients. Cell. Mol. Gastroenterol. Hepatol. 2, 750-766 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 750-766
-
-
Jacobs, J.P.1
-
123
-
-
84999751792
-
Microgeographic proteomic networks of the human colonic mucosa and their association with inflammatory bowel disease
-
Li, X. et al. Microgeographic proteomic networks of the human colonic mucosa and their association with inflammatory bowel disease. Cell. Mol. Gastroenterol. Hepatol. 2, 567-583 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 567-583
-
-
Li, X.1
-
124
-
-
33144473772
-
Genetic basis for increased intestinal permeability in families with Crohns disease: Role of CARD15 3020insC mutation?
-
Buhner, S. et al. Genetic basis for increased intestinal permeability in families with Crohns disease: role of CARD15 3020insC mutation? Gut 55, 342-347 (2006).
-
(2006)
Gut
, vol.55
, pp. 342-347
-
-
Buhner, S.1
-
125
-
-
0028907445
-
Intestinal permeability: An overview
-
Bjarnason, I., MacPherson, A. & Hollander, D. Intestinal permeability: an overview. Gastroenterology 108, 1566-1581 (1995).
-
(1995)
Gastroenterology
, vol.108
, pp. 1566-1581
-
-
Bjarnason, I.1
MacPherson, A.2
Hollander, D.3
-
126
-
-
0034465898
-
Increased intestinal permeability precedes the onset of Crohns disease in a subject with familial risk
-
Irvine, E. J. & Marshall, J. K. Increased intestinal permeability precedes the onset of Crohns disease in a subject with familial risk. Gastroenterology 119, 1740-1744 (2000).
-
(2000)
Gastroenterology
, vol.119
, pp. 1740-1744
-
-
Irvine, E.J.1
Marshall, J.K.2
-
127
-
-
46049083963
-
Unique role of junctional adhesion molecule-A in maintaining mucosal homeostasis in inflammatory bowel disease
-
Vetrano, S. et al. Unique role of junctional adhesion molecule-A in maintaining mucosal homeostasis in inflammatory bowel disease. Gastroenterology 135, 173-184 (2008).
-
(2008)
Gastroenterology
, vol.135
, pp. 173-184
-
-
Vetrano, S.1
-
128
-
-
33646002797
-
-
eds Kumar, V., Abbas, A. K. & Aster, J. C. Elsevier
-
Turner, J. R. in Robbins and Cotran Pathologic Basis of Disease (eds Kumar, V., Abbas, A. K. & Aster, J. C.) 749-819 (Elsevier, 2014).
-
(2014)
Robbins and Cotran Pathologic Basis of Disease
, pp. 749-819
-
-
Turner, J.R.1
-
129
-
-
0020060944
-
Intestinal permeability in coeliac disease: The response to gluten withdrawal and single-dose gluten challenge
-
Hamilton, I., Cobden, I., Rothwell, J. & Axon, A. T. Intestinal permeability in coeliac disease: the response to gluten withdrawal and single-dose gluten challenge. Gut 23, 202-210 (1982).
-
(1982)
Gut
, vol.23
, pp. 202-210
-
-
Hamilton, I.1
Cobden, I.2
Rothwell, J.3
Axon, A.T.4
-
130
-
-
0030915523
-
Gastrointestinal permeability in celiac disease
-
Smecuol, E. et al. Gastrointestinal permeability in celiac disease. Gastroenterology 112, 1129-1136 (1997).
-
(1997)
Gastroenterology
, vol.112
, pp. 1129-1136
-
-
Smecuol, E.1
-
131
-
-
0027409890
-
Intestinal permeability in patients with coeliac disease and relatives of patients with coeliac disease
-
van Elburg, R. M., Uil, J. J., Mulder, C. J. & Heymans, H. S. Intestinal permeability in patients with coeliac disease and relatives of patients with coeliac disease. Gut 34, 354-357 (1993).
-
(1993)
Gut
, vol.34
, pp. 354-357
-
-
Van Elburg, R.M.1
Uil, J.J.2
Mulder, C.J.3
Heymans, H.S.4
-
132
-
-
0035058421
-
Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease
-
Cummins, A. G. et al. Improvement in intestinal permeability precedes morphometric recovery of the small intestine in coeliac disease. Clin. Sci. (Lond.) 100, 379-386 (2001).
-
(2001)
Clin. Sci. (Lond.)
, vol.100
, pp. 379-386
-
-
Cummins, A.G.1
-
133
-
-
84876481254
-
A controlled trial of glutenfree diet in patients with irritable bowel syndromediarrhea: Effects on bowel frequency and intestinal function
-
Vazquez-Roque, M. I. et al. A controlled trial of glutenfree diet in patients with irritable bowel syndromediarrhea: effects on bowel frequency and intestinal function. Gastroenterology 144, 903-911.e3 (2013).
-
(2013)
Gastroenterology
, vol.144
, pp. 903-903e3
-
-
Vazquez-Roque, M.I.1
-
134
-
-
0025768190
-
Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs
-
Hall, E. J. & Batt, R. M. Abnormal permeability precedes the development of a gluten sensitive enteropathy in Irish setter dogs. Gut 32, 749-753 (1991).
-
(1991)
Gut
, vol.32
, pp. 749-753
-
-
Hall, E.J.1
Batt, R.M.2
-
135
-
-
38349112856
-
Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice
-
Verdu, E. F. et al. Gliadin-dependent neuromuscular and epithelial secretory responses in gluten-sensitive HLA-DQ8 transgenic mice. Am. J. Physiol. Gastrointest. Liver Physiol. 294, G217-G225 (2008).
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.294
, pp. G217-G225
-
-
Verdu, E.F.1
-
136
-
-
68149094492
-
Host responses to intestinal microbial antigens in gluten-sensitive mice
-
Natividad, J. M. et al. Host responses to intestinal microbial antigens in gluten-sensitive mice. PLoS ONE 4, e6472 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e6472
-
-
Natividad, J.M.1
-
137
-
-
0037302604
-
Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function
-
Clemente, M. G. et al. Early effects of gliadin on enterocyte intracellular signalling involved in intestinal barrier function. Gut 52, 218-223 (2003).
-
(2003)
Gut
, vol.52
, pp. 218-223
-
-
Clemente, M.G.1
-
138
-
-
24044493977
-
Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins
-
Sander, G. R., Cummins, A. G., Henshall, T. & Powell, B. C. Rapid disruption of intestinal barrier function by gliadin involves altered expression of apical junctional proteins. FEBS Lett. 579, 4851-4855 (2005).
-
(2005)
FEBS Lett.
, vol.579
, pp. 4851-4855
-
-
Sander, G.R.1
Cummins, A.G.2
Henshall, T.3
Powell, B.C.4
-
139
-
-
0034728821
-
Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease
-
Fasano, A. et al. Zonulin, a newly discovered modulator of intestinal permeability, and its expression in coeliac disease. Lancet 355, 1518-1519 (2000).
-
(2000)
Lancet
, vol.355
, pp. 1518-1519
-
-
Fasano, A.1
-
140
-
-
84859805588
-
Larazotide acetate regulates epithelial tight junctions in vitro and in vivo
-
Gopalakrishnan, S. et al. Larazotide acetate regulates epithelial tight junctions in vitro and in vivo. Peptides 35, 86-94 (2012).
-
(2012)
Peptides
, vol.35
, pp. 86-94
-
-
Gopalakrishnan, S.1
-
141
-
-
84872717725
-
Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: A randomised placebo-controlled study
-
Kelly, C. P. et al. Larazotide acetate in patients with coeliac disease undergoing a gluten challenge: a randomised placebo-controlled study. Aliment. Pharmacol. Ther. 37, 252-262 (2013).
-
(2013)
Aliment. Pharmacol. Ther.
, vol.37
, pp. 252-262
-
-
Kelly, C.P.1
-
142
-
-
28444452580
-
Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect
-
Monsuur, A. J. et al. Myosin IXB variant increases the risk of celiac disease and points toward a primary intestinal barrier defect. Nat. Genet. 37, 1341-1344 (2005).
-
(2005)
Nat. Genet.
, vol.37
, pp. 1341-1344
-
-
Monsuur, A.J.1
-
143
-
-
0141817736
-
A major non-HLA locus in celiac disease maps to chromosome 19
-
Van Belzen, M. J. et al. A major non-HLA locus in celiac disease maps to chromosome 19. Gastroenterology 125, 1032-1041 (2003).
-
(2003)
Gastroenterology
, vol.125
, pp. 1032-1041
-
-
Van Belzen, M.J.1
-
144
-
-
0029991890
-
Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail
-
Wirth, J. A., Jensen, K. A., Post, P. L., Bement, W. M. & Mooseker, M. S. Human myosin-IXb, an unconventional myosin with a chimerin-like rho/rac GTPase-activating protein domain in its tail. J. Cell Sci. 109, 653-661 (1996).
-
(1996)
J. Cell Sci.
, vol.109
, pp. 653-661
-
-
Wirth, J.A.1
Jensen, K.A.2
Post, P.L.3
Bement, W.M.4
Mooseker, M.S.5
-
145
-
-
0031977198
-
Human myosin-IXb is a mechanochemically active motor and a GAP for rho
-
Post, P. L., Bokoch, G. M. & Mooseker, M. S. Human myosin-IXb is a mechanochemically active motor and a GAP for rho. J. Cell Sci. 111, 941-950 (1998).
-
(1998)
J. Cell Sci.
, vol.111
, pp. 941-950
-
-
Post, P.L.1
Bokoch, G.M.2
Mooseker, M.S.3
-
146
-
-
33646574535
-
Lack of association of MYO9B genetic variants with coeliac disease in a British cohort
-
Hunt, K. A. et al. Lack of association of MYO9B genetic variants with coeliac disease in a British cohort. Gut 55, 969-972 (2006).
-
(2006)
Gut
, vol.55
, pp. 969-972
-
-
Hunt, K.A.1
-
147
-
-
33646552094
-
Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort
-
Amundsen, S. S. et al. Association analysis of MYO9B gene polymorphisms with celiac disease in a Swedish/Norwegian cohort. Hum. Immunol. 67, 341-345 (2006).
-
(2006)
Hum. Immunol.
, vol.67
, pp. 341-345
-
-
Amundsen, S.S.1
-
148
-
-
79958265603
-
Replication of genetic variation in the MYO9B gene in Crohns disease
-
Wolters, V. M. et al. Replication of genetic variation in the MYO9B gene in Crohns disease. Hum. Immunol. 72, 592-597 (2011).
-
(2011)
Hum. Immunol.
, vol.72
, pp. 592-597
-
-
Wolters, V.M.1
-
149
-
-
33845622964
-
Genetic variation in myosin IXB is associated with ulcerative colitis
-
van Bodegraven, A. A. et al. Genetic variation in myosin IXB is associated with ulcerative colitis. Gastroenterology 131, 1768-1774 (2006).
-
(2006)
Gastroenterology
, vol.131
, pp. 1768-1774
-
-
Van Bodegraven, A.A.1
-
150
-
-
69449092789
-
Association between genetic variants in myosin IXB and Crohns disease
-
Cooney, R. et al. Association between genetic variants in myosin IXB and Crohns disease. Inflamm. Bowel Dis. 15, 1014-1021 (2009).
-
(2009)
Inflamm. Bowel Dis.
, vol.15
, pp. 1014-1021
-
-
Cooney, R.1
-
151
-
-
84863516735
-
A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation
-
Chandhoke, S. K. & Mooseker, M. S. A role for myosin IXb, a motor-RhoGAP chimera, in epithelial wound healing and tight junction regulation. Mol. Biol. Cell 23, 2468-2480 (2012).
-
(2012)
Mol. Biol. Cell
, vol.23
, pp. 2468-2480
-
-
Chandhoke, S.K.1
Mooseker, M.S.2
-
152
-
-
84962892930
-
Mice lacking myosin IXb, an inflammatory bowel disease susceptibility gene, have impaired intestinal barrier function and superficial ulceration in the ileum
-
Hegan, P. S. et al. Mice lacking myosin IXb, an inflammatory bowel disease susceptibility gene, have impaired intestinal barrier function and superficial ulceration in the ileum. Cytoskeleton (Hoboken) 73, 163-179 (2016).
-
(2016)
Cytoskeleton (Hoboken)
, vol.73
, pp. 163-179
-
-
Hegan, P.S.1
-
153
-
-
85028094075
-
Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease
-
Schumann, M. et al. Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease. Gut 61, 220-228 (2012).
-
(2012)
Gut
, vol.61
, pp. 220-228
-
-
Schumann, M.1
-
154
-
-
77949720519
-
Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease
-
Szakal, D. N. et al. Mucosal expression of claudins 2, 3 and 4 in proximal and distal part of duodenum in children with coeliac disease. Virchows Arch. 456, 245-250 (2010).
-
(2010)
Virchows Arch.
, vol.456
, pp. 245-250
-
-
Szakal, D.N.1
-
155
-
-
0018724826
-
Abnormal intestinal permeability to sugars in villous atrophy
-
Menzies, I. S. et al. Abnormal intestinal permeability to sugars in villous atrophy. Lancet 2, 1107-1109 (1979).
-
(1979)
Lancet
, vol.2
, pp. 1107-1109
-
-
Menzies, I.S.1
-
156
-
-
0028879979
-
Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea
-
Keating, J. et al. Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea. Gut 37, 623-629 (1995).
-
(1995)
Gut
, vol.37
, pp. 623-629
-
-
Keating, J.1
-
157
-
-
0028972499
-
Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin
-
Hermiston, M. L. & Gordon, J. I. Inflammatory bowel disease and adenomas in mice expressing a dominant negative N-cadherin. Science 270, 1203-1207 (1995).
-
(1995)
Science
, vol.270
, pp. 1203-1207
-
-
Hermiston, M.L.1
Gordon, J.I.2
-
158
-
-
0031710227
-
Alterations in classical cadherins associated with progression in ulcerative and Crohns colitis
-
Jankowski, J. A. et al. Alterations in classical cadherins associated with progression in ulcerative and Crohns colitis. Lab. Invest. 78, 1155-1167 (1998).
-
(1998)
Lab. Invest.
, vol.78
, pp. 1155-1167
-
-
Jankowski, J.A.1
-
159
-
-
77953221408
-
P120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice
-
Smalley-Freed, W. G. et al. p120-catenin is essential for maintenance of barrier function and intestinal homeostasis in mice. J. Clin. Invest. 120, 1824-1835 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 1824-1835
-
-
Smalley-Freed, W.G.1
-
160
-
-
78650775249
-
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation
-
Schneider, M. R. et al. A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation. PLoS ONE 5, e14325 (2010).
-
(2010)
PLoS ONE
, vol.5
, pp. e14325
-
-
Schneider, M.R.1
-
161
-
-
70649103789
-
Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region
-
Barrett, J. C. et al. Genome-wide association study of ulcerative colitis identifies three new susceptibility loci, including the HNF4A region. Nat. Genet. 41, 1330-1334 (2009).
-
(2009)
Nat. Genet.
, vol.41
, pp. 1330-1334
-
-
Barrett, J.C.1
-
162
-
-
84873733916
-
IL-10R polymorphisms are associated with very-early-onset ulcerative colitis
-
Moran, C. J. et al. IL-10R polymorphisms are associated with very-early-onset ulcerative colitis. Inflamm. Bowel Dis. 19, 115-123 (2013).
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 115-123
-
-
Moran, C.J.1
-
163
-
-
70949087383
-
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
-
Glocker, E. O. et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N. Engl. J. Med. 361, 2033-2045 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2033-2045
-
-
Glocker, E.O.1
-
164
-
-
84876361518
-
Genetic susceptibility in IBD: Overlap between ulcerative colitis and Crohns disease
-
Doecke, J. D. et al. Genetic susceptibility in IBD: overlap between ulcerative colitis and Crohns disease. Inflamm. Bowel Dis. 19, 240-245 (2013).
-
(2013)
Inflamm. Bowel Dis.
, vol.19
, pp. 240-245
-
-
Doecke, J.D.1
-
165
-
-
0035192380
-
Inflammatory bowel disease: Lessons from the IL-10 gene-deficient mouse
-
Madsen, K. L. Inflammatory bowel disease: lessons from the IL-10 gene-deficient mouse. Clin. Invest. Med. 24, 250-257 (2001).
-
(2001)
Clin. Invest. Med.
, vol.24
, pp. 250-257
-
-
Madsen, K.L.1
-
166
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn, R., Lohler, J., Rennick, D., Rajewsky, K. & Muller, W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75, 263-274 (1993).
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
167
-
-
70349427086
-
Toll-like receptor 4-mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10-deficient mice
-
Matharu, K. S. et al. Toll-like receptor 4-mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10-deficient mice. Gastroenterology 137, 1380-1390.e3 (2009).
-
(2009)
Gastroenterology
, vol.137
, pp. 1380-1380e3
-
-
Matharu, K.S.1
-
168
-
-
0033228442
-
Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora
-
Madsen, K. L. et al. Interleukin-10 gene-deficient mice develop a primary intestinal permeability defect in response to enteric microflora. Inflamm. Bowel Dis. 5, 262-270 (1999).
-
(1999)
Inflamm. Bowel Dis.
, vol.5
, pp. 262-270
-
-
Madsen, K.L.1
-
169
-
-
0034116557
-
Antibiotic therapy attenuates colitis in interleukin 10 gene-deficient mice
-
Madsen, K. L. et al. Antibiotic therapy attenuates colitis in interleukin 10 gene-deficient mice. Gastroenterology 118, 1094-1105 (2000).
-
(2000)
Gastroenterology
, vol.118
, pp. 1094-1105
-
-
Madsen, K.L.1
-
170
-
-
84898809123
-
The microbiome in inflammatory bowel disease: Current status and the future ahead
-
Kostic, A. D., Xavier, R. J. & Gevers, D. The microbiome in inflammatory bowel disease: current status and the future ahead. Gastroenterology 146, 1489-1499 (2014).
-
(2014)
Gastroenterology
, vol.146
, pp. 1489-1499
-
-
Kostic, A.D.1
Xavier, R.J.2
Gevers, D.3
-
171
-
-
0036829094
-
Rapid development of colitis in NSAID-treated IL-10-deficient mice
-
Berg, D. J. et al. Rapid development of colitis in NSAID-treated IL-10-deficient mice. Gastroenterology 123, 1527-1542 (2002).
-
(2002)
Gastroenterology
, vol.123
, pp. 1527-1542
-
-
Berg, D.J.1
-
172
-
-
84925709065
-
Increasing small intestinal permeability worsens colitis in the IL-10-/-mouse and prevents the induction of oral tolerance to ovalbumin
-
Arrieta, M. C., Madsen, K. L., Field, C. J. & Meddings, J. B. Increasing small intestinal permeability worsens colitis in the IL-10-/-mouse and prevents the induction of oral tolerance to ovalbumin. Inflamm. Bowel Dis. 21, 8-18 (2015).
-
(2015)
Inflamm. Bowel Dis.
, vol.21
, pp. 8-18
-
-
Arrieta, M.C.1
Madsen, K.L.2
Field, C.J.3
Meddings, J.B.4
-
173
-
-
58249085436
-
Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
-
Arrieta, M. C., Madsen, K., Doyle, J. & Meddings, J. Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse. Gut 58, 41-48 (2009).
-
(2009)
Gut
, vol.58
, pp. 41-48
-
-
Arrieta, M.C.1
Madsen, K.2
Doyle, J.3
Meddings, J.4
-
174
-
-
0020694110
-
Graft-versus-host disease and survival in patients with aplastic anemia treated by marrow grafts from HLA-identical siblings -beneficial effect of a protective environment
-
Storb, R. et al. Graft-versus-host disease and survival in patients with aplastic anemia treated by marrow grafts from HLA-identical siblings -beneficial effect of a protective environment. N. Engl. J. Med. 308, 302-307 (1983).
-
(1983)
N. Engl. J. Med.
, vol.308
, pp. 302-307
-
-
Storb, R.1
-
175
-
-
0033011210
-
Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease
-
Brown, G. R. et al. Tumor necrosis factor inhibitor ameliorates murine intestinal graft-versus-host disease. Gastroenterology 116, 593-601 (1999).
-
(1999)
Gastroenterology
, vol.116
, pp. 593-601
-
-
Brown, G.R.1
-
176
-
-
0032533897
-
Tumor necrosis factor-a production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graftversus-host disease
-
Cooke, K. R. et al. Tumor necrosis factor-a production to lipopolysaccharide stimulation by donor cells predicts the severity of experimental acute graftversus-host disease. J. Clin. Invest. 102, 1882-1891 (1998).
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1882-1891
-
-
Cooke, K.R.1
-
177
-
-
84904512053
-
Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease
-
Nalle, S. C. et al. Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease. Sci. Transl Med. 6, 243ra87 (2014).
-
(2014)
Sci. Transl Med.
, vol.6
, pp. 243ra87
-
-
Nalle, S.C.1
-
178
-
-
33750906233
-
Increased intestinal permeability precedes clinical onset of type 1 diabetes
-
Bosi, E. et al. Increased intestinal permeability precedes clinical onset of type 1 diabetes. Diabetologia 49, 2824-2827 (2006).
-
(2006)
Diabetologia
, vol.49
, pp. 2824-2827
-
-
Bosi, E.1
-
179
-
-
0032937027
-
Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat
-
Meddings, J. B., Jarand, J., Urbanski, S. J., Hardin, J. & Gall, D. G. Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic BB rat. Am. J. Physiol. 276, G951-G957 (1999).
-
(1999)
Am. J. Physiol.
, vol.276
, pp. G951-G957
-
-
Meddings, J.B.1
Jarand, J.2
Urbanski, S.J.3
Hardin, J.4
Gall, D.G.5
-
180
-
-
53549086654
-
Microecology, obesity, and probiotics
-
Tennyson, C. A. & Friedman, G. Microecology, obesity, and probiotics. Curr. Opin. Endocrinol. Diabetes Obes. 15, 422-427 (2008).
-
(2008)
Curr. Opin. Endocrinol. Diabetes Obes.
, vol.15
, pp. 422-427
-
-
Tennyson, C.A.1
Friedman, G.2
-
181
-
-
84962190977
-
Cathelicidin antimicrobial peptide: A novel regulator of islet function, islet regeneration, and selected gut bacteria
-
Pound, L. D. et al. Cathelicidin antimicrobial peptide: a novel regulator of islet function, islet regeneration, and selected gut bacteria. Diabetes 64, 4135-4147 (2015).
-
(2015)
Diabetes
, vol.64
, pp. 4135-4147
-
-
Pound, L.D.1
-
182
-
-
84938965221
-
Role of the gastrointestinal ecosystem in the development of Type 1 diabetes
-
Daft, J. G. & Lorenz, R. G. Role of the gastrointestinal ecosystem in the development of Type 1 diabetes. Pediatr. Diabetes 16, 407-418 (2015).
-
(2015)
Pediatr. Diabetes
, vol.16
, pp. 407-418
-
-
Daft, J.G.1
Lorenz, R.G.2
-
183
-
-
54549122338
-
Innate immunity and intestinal microbiota in the development of Type 1 diabetes
-
Wen, L. et al. Innate immunity and intestinal microbiota in the development of Type 1 diabetes. Nature 455, 1109-1113 (2008).
-
(2008)
Nature
, vol.455
, pp. 1109-1113
-
-
Wen, L.1
-
184
-
-
0027166934
-
NOD mouse colonies around the world -recent facts and figures
-
Pozzilli, P., Signore, A., Williams, A. J. & Beales, P. E. NOD mouse colonies around the world -recent facts and figures. Immunol. Today 14, 193-196 (1993).
-
(1993)
Immunol. Today
, vol.14
, pp. 193-196
-
-
Pozzilli, P.1
Signore, A.2
Williams, A.J.3
Beales, P.E.4
-
185
-
-
14544277099
-
Role of the intestinal tight junction modulator zonulin in the pathogenesis of type i diabetes in BB diabetic-prone rats
-
Watts, T. et al. Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats. Proc. Natl Acad. Sci. USA 102, 2916-2921 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 2916-2921
-
-
Watts, T.1
-
186
-
-
33745311630
-
Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives
-
Sapone, A. et al. Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives. Diabetes 55, 1443-1449 (2006).
-
(2006)
Diabetes
, vol.55
, pp. 1443-1449
-
-
Sapone, A.1
-
187
-
-
84867101199
-
A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge
-
Leffler, D. A. et al. A randomized, double-blind study of larazotide acetate to prevent the activation of celiac disease during gluten challenge. Am. J. Gastroenterol. 107, 1554-1562 (2012).
-
(2012)
Am. J. Gastroenterol.
, vol.107
, pp. 1554-1562
-
-
Leffler, D.A.1
-
188
-
-
33645985802
-
Engraftment of mucosal stem cells into murine jejunum is dependent on optimal dose of cells
-
Avansino, J. R., Chen, D. C., Woolman, J. D., Hoagland, V. D. & Stelzner, M. Engraftment of mucosal stem cells into murine jejunum is dependent on optimal dose of cells. J. Surg. Res. 132, 74-79 (2006).
-
(2006)
J. Surg. Res.
, vol.132
, pp. 74-79
-
-
Avansino, J.R.1
Chen, D.C.2
Woolman, J.D.3
Hoagland, V.D.4
Stelzner, M.5
-
189
-
-
0028070612
-
Colonic mucosal replacement by syngeneic small intestinal stem cell transplantation
-
Tait, I. S., Evans, G. S., Flint, N. & Campbell, F. C. Colonic mucosal replacement by syngeneic small intestinal stem cell transplantation. Am. J. Surg. 167, 67-72 (1994).
-
(1994)
Am. J. Surg.
, vol.167
, pp. 67-72
-
-
Tait, I.S.1
Evans, G.S.2
Flint, N.3
Campbell, F.C.4
-
190
-
-
67349123408
-
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche
-
Sato, T. et al. Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche. Nature 459, 262-265 (2009).
-
(2009)
Nature
, vol.459
, pp. 262-265
-
-
Sato, T.1
-
191
-
-
84997106969
-
Epithelial regeneration after gastric ulceration causes prolonged cell-type alterations
-
Aihara, E. et al. Epithelial regeneration after gastric ulceration causes prolonged cell-type alterations. Cell. Mol. Gastroenterol. Hepatol. 2, 625-647 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 625-647
-
-
Aihara, E.1
-
192
-
-
84997419129
-
The development of spasmolytic polypeptide/TFF2-expressing metaplasia (SPEM) during gastric repair is absent in the aged stomach
-
Engevik, A. C. et al. The development of spasmolytic polypeptide/TFF2-expressing metaplasia (SPEM) during gastric repair is absent in the aged stomach. Cell. Mol. Gastroenterol. Hepatol. 2, 605-624 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 605-624
-
-
Engevik, A.C.1
-
193
-
-
84862777784
-
Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
-
Yui, S. et al. Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell. Nat. Med. 18, 618-623 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 618-623
-
-
Yui, S.1
-
194
-
-
84864854371
-
Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas
-
Schepers, A. G. et al. Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas. Science 337, 730-735 (2012).
-
(2012)
Science
, vol.337
, pp. 730-735
-
-
Schepers, A.G.1
-
195
-
-
59049106578
-
Crypt stem cells as the cells-of-origin of intestinal cancer
-
Barker, N. et al. Crypt stem cells as the cells-of-origin of intestinal cancer. Nature 457, 608-611 (2009).
-
(2009)
Nature
, vol.457
, pp. 608-611
-
-
Barker, N.1
-
196
-
-
84992535817
-
The RNA polymerase III subunit Polr3b is required for the maintenance of small intestinal crypts in mice
-
Kieckhaefer, J. et al. The RNA polymerase III subunit Polr3b is required for the maintenance of small intestinal crypts in mice. Cell. Mol. Gastroenterol. Hepatol. 2, 783-795 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 783-795
-
-
Kieckhaefer, J.1
-
197
-
-
84992655949
-
Requirement of Gaq/Ga11 signaling in the preservation of mouse intestinal epithelial homeostasis
-
Watanabe, N. et al. Requirement of Gaq/Ga11 signaling in the preservation of mouse intestinal epithelial homeostasis. Cell. Mol. Gastroenterol. Hepatol. 2, 767-782 (2016).
-
(2016)
Cell. Mol. Gastroenterol. Hepatol.
, vol.2
, pp. 767-782
-
-
Watanabe, N.1
-
198
-
-
50149105621
-
Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis
-
Yamaoka, T. et al. Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis. Proc. Natl Acad. Sci. USA 105, 11772-11777 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 11772-11777
-
-
Yamaoka, T.1
-
199
-
-
34247193001
-
R-spondin1, a novel intestinotrophic mitogen, ameliorates experimental colitis in mice
-
Zhao, J. et al. R-spondin1, a novel intestinotrophic mitogen, ameliorates experimental colitis in mice. Gastroenterology 132, 1331-1343 (2007).
-
(2007)
Gastroenterology
, vol.132
, pp. 1331-1343
-
-
Zhao, J.1
-
200
-
-
14944357138
-
Wnt, stem cells and cancer in the intestine
-
Pinto, D. & Clevers, H. Wnt, stem cells and cancer in the intestine. Biol. Cell 97, 185-196 (2005).
-
(2005)
Biol. Cell
, vol.97
, pp. 185-196
-
-
Pinto, D.1
Clevers, H.2
-
201
-
-
2942668475
-
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration
-
Sansom, O. J. et al. Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration. Genes Dev. 18, 1385-1390 (2004).
-
(2004)
Genes Dev.
, vol.18
, pp. 1385-1390
-
-
Sansom, O.J.1
-
202
-
-
84859196824
-
The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor
-
Powell, A. E. et al. The pan-ErbB negative regulator Lrig1 is an intestinal stem cell marker that functions as a tumor suppressor. Cell 149, 146-158 (2012).
-
(2012)
Cell
, vol.149
, pp. 146-158
-
-
Powell, A.E.1
-
203
-
-
84859430024
-
Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling
-
Wong, V. W. et al. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat. Cell Biol. 14, 401-408 (2012).
-
(2012)
Nat. Cell Biol.
, vol.14
, pp. 401-408
-
-
Wong, V.W.1
-
204
-
-
84864750939
-
Epidermal growth factor receptor inhibits colitis-associated cancer in mice
-
Dube, P. E. et al. Epidermal growth factor receptor inhibits colitis-associated cancer in mice. J. Clin. Invest. 122, 2780-2792 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 2780-2792
-
-
Dube, P.E.1
-
205
-
-
79961045642
-
Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension
-
He, W. Q. et al. Role of myosin light chain kinase in regulation of basal blood pressure and maintenance of salt-induced hypertension. Am. J. Physiol. Heart Circ. Physiol. 301, H584-H591 (2011).
-
(2011)
Am. J. Physiol. Heart Circ. Physiol.
, vol.301
, pp. H584-H591
-
-
He, W.Q.1
-
206
-
-
48549089459
-
Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice
-
He, W. Q. et al. Myosin light chain kinase is central to smooth muscle contraction and required for gastrointestinal motility in mice. Gastroenterology 135, 610-620 (2008).
-
(2008)
Gastroenterology
, vol.135
, pp. 610-620
-
-
He, W.Q.1
-
207
-
-
77949333284
-
Myosin light chain kinase is necessary for tonic airway smooth muscle contraction
-
Zhang, W. C. et al. Myosin light chain kinase is necessary for tonic airway smooth muscle contraction. J. Biol. Chem. 285, 5522-5531 (2010).
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 5522-5531
-
-
Zhang, W.C.1
-
208
-
-
84862871048
-
Defective tight junctions in refractory celiac disease
-
Schumann, M. et al. Defective tight junctions in refractory celiac disease. Ann. N. Y. Acad. Sci. 1258, 43-51 (2012).
-
(2012)
Ann. N. Y. Acad. Sci.
, vol.1258
, pp. 43-51
-
-
Schumann, M.1
-
209
-
-
80053521469
-
Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model
-
Noth, R. et al. Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model. BMC Gastroenterol. 11, 109 (2011).
-
(2011)
BMC Gastroenterol.
, vol.11
, pp. 109
-
-
Noth, R.1
-
210
-
-
84881030277
-
Complex roles of caspases in the pathogenesis of inflammatory bowel disease
-
Becker, C., Watson, A. J. & Neurath, M. F. Complex roles of caspases in the pathogenesis of inflammatory bowel disease. Gastroenterology 144, 283-293 (2013).
-
(2013)
Gastroenterology
, vol.144
, pp. 283-293
-
-
Becker, C.1
Watson, A.J.2
Neurath, M.F.3
-
211
-
-
66549112120
-
Pathology of graftversus-host disease in the gastrointestinal tract
-
Washington, K. & Jagasia, M. Pathology of graftversus-host disease in the gastrointestinal tract. Hum. Pathol. 40, 909-917 (2009).
-
(2009)
Hum. Pathol.
, vol.40
, pp. 909-917
-
-
Washington, K.1
Jagasia, M.2
-
212
-
-
0023927304
-
Assessment of the lactulose-mannitol test in Crohns disease
-
Andre, F. et al. Assessment of the lactulose-mannitol test in Crohns disease. Gut 29, 511-515 (1988).
-
(1988)
Gut
, vol.29
, pp. 511-515
-
-
Andre, F.1
-
213
-
-
0028125084
-
Increased permeability of macroscopically normal small bowel in Crohns disease
-
Peeters, M. et al. Increased permeability of macroscopically normal small bowel in Crohns disease. Dig. Dis. Sci. 39, 2170-2176 (1994).
-
(1994)
Dig. Dis. Sci.
, vol.39
, pp. 2170-2176
-
-
Peeters, M.1
-
214
-
-
0018894692
-
Passage of molecules through the wall of the gastrointestinal tract. II. Application of low-molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man
-
Sundqvist, T., Magnusson, K. E., Sjodahl, R., Stjernstrom, I. & Tagesson, C. Passage of molecules through the wall of the gastrointestinal tract. II. Application of low-molecular weight polyethyleneglycol and a deterministic mathematical model for determining intestinal permeability in man. Gut 21, 208-214 (1980).
-
(1980)
Gut
, vol.21
, pp. 208-214
-
-
Sundqvist, T.1
Magnusson, K.E.2
Sjodahl, R.3
Stjernstrom, I.4
Tagesson, C.5
-
215
-
-
0033635128
-
Abnormal intestinal permeability predicts relapse in inactive Crohn disease
-
Arnott, I. D., Kingstone, K. & Ghosh, S. Abnormal intestinal permeability predicts relapse in inactive Crohn disease. Scand. J. Gastroenterol. 35, 1163-1169 (2000).
-
(2000)
Scand. J. Gastroenterol.
, vol.35
, pp. 1163-1169
-
-
Arnott, I.D.1
Kingstone, K.2
Ghosh, S.3
-
216
-
-
23544454108
-
Lactulose/mannitol permeability is increased in relatives of patients with Crohns disease
-
May, G. R., Sutherland, L. M. & Meddings, J. B. Lactulose/mannitol permeability is increased in relatives of patients with Crohns disease. Gastroenterology 102, A934 (1992).
-
(1992)
Gastroenterology
, vol.102
, pp. A934
-
-
May, G.R.1
Sutherland, L.M.2
Meddings, J.B.3
-
217
-
-
0032763736
-
Sugar tests detect celiac disease among first-degree relatives
-
Smecuol, E. et al. Sugar tests detect celiac disease among first-degree relatives. Am. J. Gastroenterol. 94, 3547-3552 (1999).
-
(1999)
Am. J. Gastroenterol.
, vol.94
, pp. 3547-3552
-
-
Smecuol, E.1
-
218
-
-
11144353743
-
Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type i diabetic patients
-
Secondulfo, M. et al. Ultrastructural mucosal alterations and increased intestinal permeability in non-celiac, type I diabetic patients. Dig. Liver Dis. 36, 35-45 (2004).
-
(2004)
Dig. Liver Dis.
, vol.36
, pp. 35-45
-
-
Secondulfo, M.1
-
219
-
-
34247598857
-
Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis
-
Poritz, L. S. et al. Loss of the tight junction protein ZO-1 in dextran sulfate sodium induced colitis. J. Surg. Res. 140, 12-19 (2007).
-
(2007)
J. Surg. Res.
, vol.140
, pp. 12-19
-
-
Poritz, L.S.1
-
220
-
-
67650667753
-
Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis
-
Yan, Y. et al. Temporal and spatial analysis of clinical and molecular parameters in dextran sodium sulfate induced colitis. PLoS ONE 4, e6073 (2009).
-
(2009)
PLoS ONE
, vol.4
, pp. e6073
-
-
Yan, Y.1
-
221
-
-
34547830319
-
Gut toxicity during hemopoietic stem cell transplantation may predict acute graft-versus-host disease severity in patients
-
Johansson, J. E. & Ekman, T. Gut toxicity during hemopoietic stem cell transplantation may predict acute graft-versus-host disease severity in patients. Dig. Dis. Sci. 52, 2340-2345 (2007).
-
(2007)
Dig. Dis. Sci.
, vol.52
, pp. 2340-2345
-
-
Johansson, J.E.1
Ekman, T.2
-
222
-
-
77949272755
-
Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice
-
Lee, A. S. et al. Gut barrier disruption by an enteric bacterial pathogen accelerates insulitis in NOD mice. Diabetologia 53, 741-748 (2010).
-
(2010)
Diabetologia
, vol.53
, pp. 741-748
-
-
Lee, A.S.1
|