-
1
-
-
0016723594
-
An endotoxin-induced serum factor that causes necrosis of tumors
-
Carswell EA, et al. (1975) An endotoxin-induced serum factor that causes necrosis of tumors. Proc Natl Acad Sci USA 72:3666-3670.
-
(1975)
Proc Natl Acad Sci USA
, vol.72
, pp. 3666-3670
-
-
Carswell, E.A.1
-
2
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0041853690
-
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes
-
Micheau O, Tschopp J (2003) Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes. Cell 114:181-190.
-
(2003)
Cell
, vol.114
, pp. 181-190
-
-
Micheau, O.1
Tschopp, J.2
-
4
-
-
0035893385
-
Kinase suppressor of Ras determines survival of intestinal cells exposed to tumor necrosis factor
-
Yan F, John SK, Polk DB (2001) Kinase suppressor of Ras determines survival of intestinal cells exposed to tumor necrosis factor. Cancer Res 61:8668-8675.
-
(2001)
Cancer Res
, vol.61
, pp. 8668-8675
-
-
Yan, F.1
John, S.K.2
Polk, D.B.3
-
5
-
-
15244361961
-
Kinase suppressor of Ras protects intestinal epithelium from cytokine-mediated apoptosis during inflammation
-
Yan F, et al. (2004) Kinase suppressor of Ras protects intestinal epithelium from cytokine-mediated apoptosis during inflammation. J Clin Invest 114:1272-1280.
-
(2004)
J Clin Invest
, vol.114
, pp. 1272-1280
-
-
Yan, F.1
-
6
-
-
0037185020
-
Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells
-
Yan F, Polk DB (2002) Probiotic bacterium prevents cytokine-induced apoptosis in intestinal epithelial cells. J Biol Chem 277:50959-50965.
-
(2002)
J Biol Chem
, vol.277
, pp. 50959-50965
-
-
Yan, F.1
Polk, D.B.2
-
7
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252.
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
8
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 Map kinases on apoptosis
-
Xia Z, Dickens M, Rainegeaud J, Davis RJ, Greenberg ME (1995) Opposing effects of ERK and JNK-p38 Map kinases on apoptosis. Science 270:1326-1331.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Rainegeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
9
-
-
33745828702
-
EGF-ERBB signalling: Towards the systems level
-
Citri A, Yarden Y (2006) EGF-ERBB signalling: Towards the systems level. Nat Rev Mol Cell Biol 7:505-516.
-
(2006)
Nat Rev Mol Cell Biol
, vol.7
, pp. 505-516
-
-
Citri, A.1
Yarden, Y.2
-
10
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
Citri A, Skaria KB, Yarden Y (2003) The deaf and the dumb: The biology of ErbB-2 and ErbB-3. Exp Cell Res 284:54-65.
-
(2003)
Exp Cell Res
, vol.284
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
11
-
-
0037429722
-
ErbB-4: Mechanism of action and biology
-
Carpenter G (2003) ErbB-4: Mechanism of action and biology. Exp Cell Res 284:66-77.
-
(2003)
Exp Cell Res
, vol.284
, pp. 66-77
-
-
Carpenter, G.1
-
12
-
-
0033214444
-
The EGF receptor as central transducer of heterologous signalling systems
-
Zwick E, Hackel PO, Prenzel N, Ullrich A (1999) The EGF receptor as central transducer of heterologous signalling systems. Trends Pharmacol Sci 20:408-412.
-
(1999)
Trends Pharmacol Sci
, vol.20
, pp. 408-412
-
-
Zwick, E.1
Hackel, P.O.2
Prenzel, N.3
Ullrich, A.4
-
13
-
-
4544275215
-
Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication
-
Argast GM, Campbell JS, Brooling JT, Fausto N (2004) Epidermal growth factor receptor transactivation mediates tumor necrosis factor-induced hepatocyte replication. J Biol Chem 279:34530-34536.
-
(2004)
J Biol Chem
, vol.279
, pp. 34530-34536
-
-
Argast, G.M.1
Campbell, J.S.2
Brooling, J.T.3
Fausto, N.4
-
14
-
-
2442427510
-
Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha
-
Chen WN, et al. (2004) Induced autocrine signaling through the epidermal growth factor receptor contributes to the response of mammary epithelial cells to tumor necrosis factor alpha. J Biol Chem 279:18488-18496.
-
(2004)
J Biol Chem
, vol.279
, pp. 18488-18496
-
-
Chen, W.N.1
-
15
-
-
20044376846
-
IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells
-
Itoh Y, et al. (2005) IL-8 promotes cell proliferation and migration through metalloproteinase-cleavage proHB-EGF in human colon carcinoma cells. Cytokine 29:275-282.
-
(2005)
Cytokine
, vol.29
, pp. 275-282
-
-
Itoh, Y.1
-
16
-
-
4143111325
-
The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells
-
Tanida S, et al. (2004) The mechanism of cleavage of EGFR ligands induced by inflammatory cytokines in gastric cancer cells. Gastroenterology 127:559-569.
-
(2004)
Gastroenterology
, vol.127
, pp. 559-569
-
-
Tanida, S.1
-
18
-
-
0033573921
-
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
-
Tice DA, Biscardi JS, Nickles AL, Parsons SJ (1999) Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc Natl Acad Sci USA 96:1415-1420.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 1415-1420
-
-
Tice, D.A.1
Biscardi, J.S.2
Nickles, A.L.3
Parsons, S.J.4
-
21
-
-
0027529085
-
Analysis of enteropathy induced by tumour necrosis factor α
-
Garside P, Bunce C, Tomlinson RC, Nichols BL, Mowat AM (1993) Analysis of enteropathy induced by tumour necrosis factor α. Cytokine 5:24-30.
-
(1993)
Cytokine
, vol.5
, pp. 24-30
-
-
Garside, P.1
Bunce, C.2
Tomlinson, R.C.3
Nichols, B.L.4
Mowat, A.M.5
-
22
-
-
0027446322
-
Natural killer cells and tumour necrosis factor-α-mediated enteropathy in mice
-
Garside P, Mowat AM (1993) Natural killer cells and tumour necrosis factor-α-mediated enteropathy in mice. Immunology 78:335-337.
-
(1993)
Immunology
, vol.78
, pp. 335-337
-
-
Garside, P.1
Mowat, A.M.2
-
23
-
-
36549065297
-
Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy
-
Kiesslich R, et al. (2007) Identification of epithelial gaps in human small and large intestine by confocal endomicroscopy. Gastroenterology 133:1769-1778.
-
(2007)
Gastroenterology
, vol.133
, pp. 1769-1778
-
-
Kiesslich, R.1
-
24
-
-
7244257577
-
Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling
-
Frey MR, Golovin A, Polk DB (2004) Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling. J Biol Chem 279:44513-44521.
-
(2004)
J Biol Chem
, vol.279
, pp. 44513-44521
-
-
Frey, M.R.1
Golovin, A.2
Polk, D.B.3
-
25
-
-
0030970550
-
Tumor necrosis factor α regulates proliferation in a mouse intestinal cell line
-
Kaiser GC, Polk DB (1997) Tumor necrosis factor α regulates proliferation in a mouse intestinal cell line. Gastroenterology 112:1231-1240.
-
(1997)
Gastroenterology
, vol.112
, pp. 1231-1240
-
-
Kaiser, G.C.1
Polk, D.B.2
-
26
-
-
0033563648
-
Conversion of TNFα from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase
-
Kaiser GC, Yan F, Polk DB (1999) Conversion of TNFα from antiproliferative to proliferative ligand in mouse intestinal epithelial cells by regulating mitogen-activated protein kinase. Exp Cell Res 249:349-358.
-
(1999)
Exp Cell Res
, vol.249
, pp. 349-358
-
-
Kaiser, G.C.1
Yan, F.2
Polk, D.B.3
-
27
-
-
33847726589
-
Gefitinib reverses TRAIL resistance inhumanbladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression
-
Shrader M, et al. (2007) Gefitinib reverses TRAIL resistance inhumanbladder cancer cell lines via inhibition of AKT-mediated X-linked inhibitor of apoptosis protein expression. Cancer Res 67:1430-1435.
-
(2007)
Cancer Res
, vol.67
, pp. 1430-1435
-
-
Shrader, M.1
-
28
-
-
34250350049
-
Transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor-alpha through the TAK1-p38 signaling pathway
-
Singhirunnusorn P, et al. (2007) Transient suppression of ligand-mediated activation of epidermal growth factor receptor by tumor necrosis factor-alpha through the TAK1-p38 signaling pathway. J Biol Chem 282:12698-12706.
-
(2007)
J Biol Chem
, vol.282
, pp. 12698-12706
-
-
Singhirunnusorn, P.1
-
29
-
-
19944366232
-
Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib
-
Ueno Y, et al. (2005) Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib. Br J Cancer 92:1690-1695.
-
(2005)
Br J Cancer
, vol.92
, pp. 1690-1695
-
-
Ueno, Y.1
-
30
-
-
0028236232
-
Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease
-
Breese EJ, et al. (1994) Tumor necrosis factor α-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106:1455-1466.
-
(1994)
Gastroenterology
, vol.106
, pp. 1455-1466
-
-
Breese, E.J.1
-
31
-
-
0031771563
-
Local cytokine response in Helicobacter pylori-infected subjects
-
Lindholm C, Quiding-Jarbrink M, Lonroth H, Hamlet A, Svennerholm AM (1998) Local cytokine response in Helicobacter pylori-infected subjects. Infect Immun 66:5964-5971.
-
(1998)
Infect Immun
, vol.66
, pp. 5964-5971
-
-
Lindholm, C.1
Quiding-Jarbrink, M.2
Lonroth, H.3
Hamlet, A.4
Svennerholm, A.M.5
-
32
-
-
0030897178
-
Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer
-
Malecka-Panas E, et al. (1997) Differential activation of total and EGF receptor (EGF-R) tyrosine kinase (tyr-k) in the rectal mucosa in patients with adenomatous polyps, ulcerative colitis and colon cancer. Hepatogastroenterology 44:435-440.
-
(1997)
Hepatogastroenterology
, vol.44
, pp. 435-440
-
-
Malecka-Panas, E.1
-
33
-
-
0030944455
-
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
-
Graus-Porta D, Beerli RR, Daly JM, Hynes NE (1997) ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling. EMBO J 16:1647-1655.
-
(1997)
EMBO J
, vol.16
, pp. 1647-1655
-
-
Graus-Porta, D.1
Beerli, R.R.2
Daly, J.M.3
Hynes, N.E.4
-
34
-
-
0032526729
-
Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers
-
Lenferink AE, et al. (1998) Differential endocytic routing of homo- and hetero-dimeric ErbB tyrosine kinases confers signaling superiority to receptor heterodimers. EMBO J 17:3385-3397.
-
(1998)
EMBO J
, vol.17
, pp. 3385-3397
-
-
Lenferink, A.E.1
-
35
-
-
0031840484
-
ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner
-
Olayioye MA, et al. (1998) ErbB-1 and ErbB-2 acquire distinct signaling properties dependent upon their dimerization partner. Mol Cell Biol 18:5042-5051.
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5042-5051
-
-
Olayioye, M.A.1
-
36
-
-
0033605560
-
ErbB-2 amplification inhibits downregulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
-
Worthylake R, Opresko LK, Wiley HS (1999) ErbB-2 amplification inhibits downregulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J Biol Chem 274:8865-8874.
-
(1999)
J Biol Chem
, vol.274
, pp. 8865-8874
-
-
Worthylake, R.1
Opresko, L.K.2
Wiley, H.S.3
-
37
-
-
0028156927
-
Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: A mechanism of interreceptor kinase activation and transphosphorylation
-
Qian X, LeVea CM, Freeman JK, Dougall WC, Greene MI (1994) Heterodimerization of epidermal growth factor receptor and wild-type or kinase-deficient Neu: A mechanism of interreceptor kinase activation and transphosphorylation. Proc Natl Acad Sci USA 91:1500-1504.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1500-1504
-
-
Qian, X.1
LeVea, C.M.2
Freeman, J.K.3
Dougall, W.C.4
Greene, M.I.5
-
38
-
-
0030968648
-
Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB-2/neu
-
Worthylake R, Wiley HS (1997) Structural aspects of the epidermal growth factor receptor required for transmodulation of erbB-2/neu. J Biol Chem 272:8594-8601.
-
(1997)
J Biol Chem
, vol.272
, pp. 8594-8601
-
-
Worthylake, R.1
Wiley, H.S.2
-
39
-
-
38849171267
-
Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis
-
Popivanova BK, et al. (2008) Blocking TNF-alpha in mice reduces colorectal carcinogenesis associated with chronic colitis. J Clin Invest 118:560-570.
-
(2008)
J Clin Invest
, vol.118
, pp. 560-570
-
-
Popivanova, B.K.1
-
40
-
-
33846600427
-
PTEN-deficient intestinal stem cells initiate intestinal polyposis
-
He XC, et al. (2007) PTEN-deficient intestinal stem cells initiate intestinal polyposis. Nat Genet 39:189-198.
-
(2007)
Nat Genet
, vol.39
, pp. 189-198
-
-
He, X.C.1
-
41
-
-
0027498506
-
Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice
-
Whitehead RH, VanEeden PE, Noble MD, Ataliotis P, Jat PS (1993) Establishment of conditionally immortalized epithelial cell lines from both colon and small intestine of adult H-2Kb-tsA58 transgenic mice. Proc Natl Acad Sci USA 90:587-591.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 587-591
-
-
Whitehead, R.H.1
VanEeden, P.E.2
Noble, M.D.3
Ataliotis, P.4
Jat, P.S.5
-
42
-
-
38349137362
-
Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration
-
Dise RS, Frey MR, Whitehead RH, Polk DB (2008) Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration. Am J Physiol Gastrointest Liver Physiol 294:G276-G285.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.294
-
-
Dise, R.S.1
Frey, M.R.2
Whitehead, R.H.3
Polk, D.B.4
-
43
-
-
0028344729
-
The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase
-
Luetteke NC, et al. (1994) The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev 8:399-413.
-
(1994)
Genes Dev
, vol.8
, pp. 399-413
-
-
Luetteke, N.C.1
-
44
-
-
0028234234
-
Ontogenic regulation of PLCγ1 activity and expression in the rat small intestine
-
Polk DB (1994) Ontogenic regulation of PLCγ1 activity and expression in the rat small intestine. Gastroenterology 107:109-116.
-
(1994)
Gastroenterology
, vol.107
, pp. 109-116
-
-
Polk, D.B.1
|