Loss of claudins 2 and 15 from mice causes defects in paracellular Na + flow and nutrient transport in gut and leads to death from malnutrition

Gastroenterology

Volumn 144, Issue 2, 2013, Pages 369-380

  Wada, Masami ^a   Tamura, Atsushi ^a   Takahashi, Nobuyuki ^b   Tsukita, Sachiko ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Claudin 15; Claudin 2; Nutrient malabsorption

Indexed keywords

AMINO ACID; CLAUDIN; CLAUDIN 15; CLAUDIN 2; FAT; GLUCOSE; SODIUM ION; UNCLASSIFIED DRUG; SODIUM;

AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ARTICLE; CELL ADHESION; CONTROLLED STUDY; GLUCOSE ABSORPTION; INTESTINE ABSORPTION; KNOCKOUT MOUSE; LIPID ABSORPTION; MALABSORPTION; MALNUTRITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; SMALL INTESTINE; SODIUM CELL LEVEL; SUBMUCOSA; TIGHT JUNCTION; UPREGULATION; ANIMAL; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; COMPARATIVE STUDY; DISEASE MODEL; ELECTRON MICROSCOPY; EPITHELIUM CELL; FLUORESCENCE MICROSCOPY; GENETICS; IMMUNOBLOTTING; INTESTINE MUCOSA; METABOLISM; MORTALITY; MOUSE MUTANT; PHENOTYPE; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TRANSPORT AT THE CELLULAR LEVEL; ULTRASTRUCTURE;

AMINO ACIDS; ANIMALS; BIOLOGICAL TRANSPORT; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CLAUDIN-2; CLAUDINS; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; FATS; GLUCOSE; IMMUNOBLOTTING; INTESTINAL ABSORPTION; INTESTINAL MUCOSA; INTESTINE, SMALL; MALNUTRITION; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON; MICROSCOPY, FLUORESCENCE; PHENOTYPE; REAL-TIME POLYMERASE CHAIN REACTION; SODIUM; TIGHT JUNCTIONS;

EID: 84881534032     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2012.10.035     Document Type: Article

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