-
1
-
-
0027369395
-
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene
-
Sadlack B, Merz H, Schorle H, Schimpl A, Feller AC, et al. (1993) Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene. Cell 75: 253-261.
-
(1993)
Cell
, vol.75
, pp. 253-261
-
-
Sadlack, B.1
Merz, H.2
Schorle, H.3
Schimpl, A.4
Feller, A.C.5
-
2
-
-
0027521572
-
Interleukin-10-deficient mice develop chronic enterocolitis
-
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W (1993) Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274.
-
(1993)
Cell
, vol.75
, pp. 263-274
-
-
Kuhn, R.1
Lohler, J.2
Rennick, D.3
Rajewsky, K.4
Muller, W.5
-
3
-
-
0027922467
-
Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice
-
Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, et al. (1993) Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell 75: 274-282.
-
(1993)
Cell
, vol.75
, pp. 274-282
-
-
Mombaerts, P.1
Mizoguchi, E.2
Grusby, M.J.3
Glimcher, L.H.4
Bhan, A.K.5
-
4
-
-
0029828745
-
Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor
-
Mashimo H, Wu DC, Podolsky DK, Fishman MC (1996) Impaired defense of intestinal mucosa in mice lacking intestinal trefoil factor. Science 274: 262-265.
-
(1996)
Science
, vol.274
, pp. 262-265
-
-
Mashimo, H.1
Wu, D.C.2
Podolsky, D.K.3
Fishman, M.C.4
-
5
-
-
0033103805
-
Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: Implications for joint and gut-associated immunopathologies
-
Kontoyiannis D, Pasparakis M, Pizarro TT, Cominelli F, Kollias G (1999) Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies. Immunity 10: 387-398.
-
(1999)
Immunity
, vol.10
, pp. 387-398
-
-
Kontoyiannis, D.1
Pasparakis, M.2
Pizarro, T.T.3
Cominelli, F.4
Kollias, G.5
-
6
-
-
0035990093
-
Animal models of inflammatory bowel disease
-
Hibi T, Ogata H, Sakuraba A (2002) Animal models of inflammatory bowel disease. J Gastroenterol 37: 409-417.
-
(2002)
J Gastroenterol
, vol.37
, pp. 409-417
-
-
Hibi, T.1
Ogata, H.2
Sakuraba, A.3
-
7
-
-
0033558364
-
Cutting edge: Chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens
-
Wirtz S, Finotto S, Kanzler S, Lohse AW, Blessing M, et al. (1999) Cutting edge: chronic intestinal inflammation in STAT-4 transgenic mice: characterization of disease and adoptive transfer by TNF- plus IFN-gamma-producing CD4+ T cells that respond to bacterial antigens. J Immunol 162: 1884-1888.
-
(1999)
J Immunol
, vol.162
, pp. 1884-1888
-
-
Wirtz, S.1
Finotto, S.2
Kanzler, S.3
Lohse, A.W.4
Blessing, M.5
-
8
-
-
0025633436
-
Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: An animal model of HLA-B27-associated human disorders
-
Hammer RE, Maika SD, Richardson JA, Tang JP, Taurog JD (1990) Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders. Cell 63: 1099-1112.
-
(1990)
Cell
, vol.63
, pp. 1099-1112
-
-
Hammer, R.E.1
Maika, S.D.2
Richardson, J.A.3
Tang, J.P.4
Taurog, J.D.5
-
9
-
-
0032536827
-
CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper cell type 1 response and ability to transfer disease
-
Cong Y, Brandwein SL, McCabe RP, Lazenby A, Birkenmeier EH, et al. (1998) CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J Exp Med 187: 855-864.
-
(1998)
J Exp Med
, vol.187
, pp. 855-864
-
-
Cong, Y.1
Brandwein, S.L.2
McCabe, R.P.3
Lazenby, A.4
Birkenmeier, E.H.5
-
10
-
-
22344435384
-
Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease
-
Odashima M, Bamias G, Rivera-Nieves J, Linden J, Nast CC, et al. (2005) Activation of A2A adenosine receptor attenuates intestinal inflammation in animal models of inflammatory bowel disease. Gastroenterology 129: 26-33.
-
(2005)
Gastroenterology
, vol.129
, pp. 26-33
-
-
Odashima, M.1
Bamias, G.2
Rivera-Nieves, J.3
Linden, J.4
Nast, C.C.5
-
11
-
-
0024552818
-
Hapten-induced model of chronic inflammation and ulceration in the rat colon
-
Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk MR, et al. (1989) Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 96: 795-803.
-
(1989)
Gastroenterology
, vol.96
, pp. 795-803
-
-
Morris, G.P.1
Beck, P.L.2
Herridge, M.S.3
Depew, W.T.4
Szewczuk, M.R.5
-
12
-
-
0028861975
-
Antibodies to interleukin 12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W (1995) Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med 182: 1281-1290.
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.2
Kelsall, B.L.3
Stuber, E.4
Strober, W.5
-
13
-
-
0025181580
-
A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
-
Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, et al. (1990) A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology 98: 694-702.
-
(1990)
Gastroenterology
, vol.98
, pp. 694-702
-
-
Okayasu, I.1
Hatakeyama, S.2
Yamada, M.3
Ohkusa, T.4
Inagaki, Y.5
-
14
-
-
0023706684
-
Systemic uptake and intestinal inflammatory effects of luminal bacterial cell wall polymers in rats with acute colonic injury
-
Sartor RB, Bond TM, Schwab JH (1988) Systemic uptake and intestinal inflammatory effects of luminal bacterial cell wall polymers in rats with acute colonic injury. Infect Immun 56: 2101-2108.
-
(1988)
Infect Immun
, vol.56
, pp. 2101-2108
-
-
Sartor, R.B.1
Bond, T.M.2
Schwab, J.H.3
-
15
-
-
0033198580
-
Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells
-
Steinhoff U, Brinkmann V, Klemm U, Aichele P, Seiler P, et al. (1999) Autoimmune intestinal pathology induced by hsp60-specific CD8 T cells. Immunity 11: 349-358.
-
(1999)
Immunity
, vol.11
, pp. 349-358
-
-
Steinhoff, U.1
Brinkmann, V.2
Klemm, U.3
Aichele, P.4
Seiler, P.5
-
17
-
-
0027224059
-
Clinicopathologic study of dextran sulfate sodium experimental murine colitis
-
Cooper HS, Murthy SN, Shah RS, Sedergran DJ (1993) Clinicopathologic study of dextran sulfate sodium experimental murine colitis. Lab Invest 69: 238-249.
-
(1993)
Lab Invest
, vol.69
, pp. 238-249
-
-
Cooper, H.S.1
Murthy, S.N.2
Shah, R.S.3
Sedergran, D.J.4
-
18
-
-
0033960121
-
Development of dextran sulphate sodium-induced experimental colitis is suppressed in genetically mast cell-deficient Ws/Ws rats
-
Araki Y, Andoh A, Fujiyama Y, Bamba T (2000) Development of dextran sulphate sodium-induced experimental colitis is suppressed in genetically mast cell-deficient Ws/Ws rats. Clin Exp Immunol 119: 264-269.
-
(2000)
Clin Exp Immunol
, vol.119
, pp. 264-269
-
-
Araki, Y.1
Andoh, A.2
Fujiyama, Y.3
Bamba, T.4
-
19
-
-
2142813761
-
A porous defense: The leaky epithelial barrier in intestinal disease
-
Clayburgh DR, Shen L, Turner JR (2004) A porous defense: the leaky epithelial barrier in intestinal disease. Lab Invest 84: 282-291.
-
(2004)
Lab Invest
, vol.84
, pp. 282-291
-
-
Clayburgh, D.R.1
Shen, L.2
Turner, J.R.3
-
20
-
-
4844229767
-
Review article: The aetiopathogenesis of inflammatory bowel disease-immunology and repair mechanisms
-
Dignass AU, Baumgart DC, Sturm A (2004) Review article: the aetiopathogenesis of inflammatory bowel disease-immunology and repair mechanisms. Aliment Pharmacol Ther 20 Suppl 4: 9-17.
-
(2004)
Aliment Pharmacol Ther
, vol.20
, Issue.SUPPL. 4
, pp. 9-17
-
-
Dignass, A.U.1
Baumgart, D.C.2
Sturm, A.3
-
21
-
-
0033158529
-
Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium
-
Kitajima S, Takuma S, Morimoto M (1999) Changes in colonic mucosal permeability in mouse colitis induced with dextran sulfate sodium. Exp Anim 48: 137-143.
-
(1999)
Exp Anim
, vol.48
, pp. 137-143
-
-
Kitajima, S.1
Takuma, S.2
Morimoto, M.3
-
22
-
-
0033773235
-
Increased permeability in dextran sulphate colitis in rats: Time course of development and effect of butyrate
-
Venkatraman A, Ramakrishna BS, Pulimood AB, Patra S, Murthy S (2000) Increased permeability in dextran sulphate colitis in rats: time course of development and effect of butyrate. Scand J Gastroenterol 35: 1053-1059.
-
(2000)
Scand J Gastroenterol
, vol.35
, pp. 1053-1059
-
-
Venkatraman, A.1
Ramakrishna, B.S.2
Pulimood, A.B.3
Patra, S.4
Murthy, S.5
-
23
-
-
53249123179
-
Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation
-
Liu N, Nguyen L, Chun RF, Lagishetty V, Ren S, et al. (2008) Altered endocrine and autocrine metabolism of vitamin D in a mouse model of gastrointestinal inflammation. Endocrinology 149: 4799-4808.
-
(2008)
Endocrinology
, vol.149
, pp. 4799-4808
-
-
Liu, N.1
Nguyen, L.2
Chun, R.F.3
Lagishetty, V.4
Ren, S.5
-
24
-
-
0033957727
-
Specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice
-
Hartmann G, Bidlingmaier C, Siegmund B, Albrich S, Schulze J, et al. (2000) Specific type IV phosphodiesterase inhibitor rolipram mitigates experimental colitis in mice. J Pharmacol Exp Ther 292: 22-30.
-
(2000)
J Pharmacol Exp Ther
, vol.292
, pp. 22-30
-
-
Hartmann, G.1
Bidlingmaier, C.2
Siegmund, B.3
Albrich, S.4
Schulze, J.5
-
25
-
-
0035193261
-
Adenosine kinase inhibitor GP515 improves experimental colitis in mice
-
Siegmund B, Rieder F, Albrich S, Wolf K, Bidlingmaier C, et al. (2001) Adenosine kinase inhibitor GP515 improves experimental colitis in mice. J Pharmacol Exp Ther 296: 99-105.
-
(2001)
J Pharmacol Exp Ther
, vol.296
, pp. 99-105
-
-
Siegmund, B.1
Rieder, F.2
Albrich, S.3
Wolf, K.4
Bidlingmaier, C.5
-
26
-
-
31044455375
-
JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells
-
Li DQ, Luo L, Chen Z, Kim HS, Song XJ, et al. (2006) JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. Exp Eye Res 82: 588-596.
-
(2006)
Exp Eye Res
, vol.82
, pp. 588-596
-
-
Li, D.Q.1
Luo, L.2
Chen, Z.3
Kim, H.S.4
Song, X.J.5
-
27
-
-
0036735192
-
Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells
-
Nemeth ZH, Deitch EA, Szabo C, Hasko G (2002) Hyperosmotic stress induces nuclear factor-kappaB activation and interleukin-8 production in human intestinal epithelial cells. Am J Pathol 161: 987-996.
-
(2002)
Am J Pathol
, vol.161
, pp. 987-996
-
-
Nemeth, Z.H.1
Deitch, E.A.2
Szabo, C.3
Hasko, G.4
-
28
-
-
57349090695
-
Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A
-
Schwartz L, Abolhassani M, Pooya M, Steyaert JM, Wertz X, et al. (2008) Hyperosmotic stress contributes to mouse colonic inflammation through the methylation of protein phosphatase 2A. Am J Physiol Gastrointest Liver Physiol 295: G934-941.
-
(2008)
Am J Physiol Gastrointest Liver Physiol
, vol.295
-
-
Schwartz, L.1
Abolhassani, M.2
Pooya, M.3
Steyaert, J.M.4
Wertz, X.5
-
29
-
-
46849091975
-
TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration
-
Yamamoto S, Shimizu S, Kiyonaka S, Takahashi N, Wajima T, et al. (2008) TRPM2-mediated Ca2+influx induces chemokine production in monocytes that aggravates inflammatory neutrophil infiltration. Nat Med 14: 738-747.
-
(2008)
Nat Med
, vol.14
, pp. 738-747
-
-
Yamamoto, S.1
Shimizu, S.2
Kiyonaka, S.3
Takahashi, N.4
Wajima, T.5
-
30
-
-
0030175929
-
The basis of current and future therapy for inflammatory bowel disease
-
Elson CO (1996) The basis of current and future therapy for inflammatory bowel disease. Am J Med 100: 656-662.
-
(1996)
Am J Med
, vol.100
, pp. 656-662
-
-
Elson, C.O.1
-
31
-
-
0028069352
-
Cytokines in intestinal inflammation: Pathophysiological and clinical considerations
-
Sartor RB (1994) Cytokines in intestinal inflammation: pathophysiological and clinical considerations. Gastroenterology 106: 533-539.
-
(1994)
Gastroenterology
, vol.106
, pp. 533-539
-
-
Sartor, R.B.1
-
32
-
-
44449159941
-
PACAP provides colonic protection against dextran sodium sulfate induced colitis
-
Azuma YT, Hagi K, Shintani N, Kuwamura M, Nakajima H, et al. (2008) PACAP provides colonic protection against dextran sodium sulfate induced colitis. J Cell Physiol 216: 111-119.
-
(2008)
J Cell Physiol
, vol.216
, pp. 111-119
-
-
Azuma, Y.T.1
Hagi, K.2
Shintani, N.3
Kuwamura, M.4
Nakajima, H.5
-
33
-
-
0029791910
-
Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes
-
Ni J, Chen SF, Hollander D (1996) Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes. Gut 39: 234-241.
-
(1996)
Gut
, vol.39
, pp. 234-241
-
-
Ni, J.1
Chen, S.F.2
Hollander, D.3
-
34
-
-
0031573593
-
A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease
-
Plevy SE, Landers CJ, Prehn J, Carramanzana NM, Deem RL, et al. (1997) A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease. J Immunol 159: 6276-6282.
-
(1997)
J Immunol
, vol.159
, pp. 6276-6282
-
-
Plevy, S.E.1
Landers, C.J.2
Prehn, J.3
Carramanzana, N.M.4
Deem, R.L.5
-
35
-
-
28844444159
-
Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: Central role of epithelial-derived MMP
-
Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, et al. (2005) Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology 129: 1991-2008.
-
(2005)
Gastroenterology
, vol.129
, pp. 1991-2008
-
-
Castaneda, F.E.1
Walia, B.2
Vijay-Kumar, M.3
Patel, N.R.4
Roser, S.5
-
36
-
-
0037092591
-
Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis
-
Gewirtz AT, Collier-Hyams LS, Young AN, Kucharzik T, Guilford WJ, et al. (2002) Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis. J Immunol 168: 5260-5267.
-
(2002)
J Immunol
, vol.168
, pp. 5260-5267
-
-
Gewirtz, A.T.1
Collier-Hyams, L.S.2
Young, A.N.3
Kucharzik, T.4
Guilford, W.J.5
-
37
-
-
0035821249
-
Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia
-
Furuta GT, Turner JR, Taylor CT, Hershberg RM, Comerford K, et al. (2001) Hypoxia-inducible factor 1-dependent induction of intestinal trefoil factor protects barrier function during hypoxia. J Exp Med 193: 1027-1034.
-
(2001)
J Exp Med
, vol.193
, pp. 1027-1034
-
-
Furuta, G.T.1
Turner, J.R.2
Taylor, C.T.3
Hershberg, R.M.4
Comerford, K.5
|