-
1
-
-
78649489009
-
Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DP, Barrett JC, et al. Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42:1118-1125.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.2
Barrett, J.C.3
-
2
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR, et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science. 2006; 314:1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
3
-
-
34247554965
-
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis
-
Rioux JD, Xavier RJ, Taylor KD, et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat Genet. 2007;39:596-604.
-
(2007)
Nat Genet
, vol.39
, pp. 596-604
-
-
Rioux, J.D.1
Xavier, R.J.2
Taylor, K.D.3
-
4
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007;39:207-211.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
5
-
-
34247579326
-
Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4
-
Libioulle C, Louis E, Hansoul S, et al. Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PloS Genet. 2007;3:538-543.
-
(2007)
PloS Genet
, vol.3
, pp. 538-543
-
-
Libioulle, C.1
Louis, E.2
Hansoul, S.3
-
6
-
-
84969213492
-
Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls
-
The Wellcome Trust Case Control Consortium
-
The Wellcome Trust Case Control Consortium. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature. 2007;447:661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
7
-
-
79952195585
-
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
-
Anderson CA, Boucher G, Lees CW, et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet. 2011;43:246-252.
-
(2011)
Nat Genet
, vol.43
, pp. 246-252
-
-
Anderson, C.A.1
Boucher, G.2
Lees, C.W.3
-
8
-
-
0034886388
-
The NOD2 gene in Crohn's disease: Implications for future research into the genetics and immunology of Crohn's disease
-
Cho JH. The NOD2 gene in Crohn's disease: implications for future research into the genetics and immunology of Crohn's disease. Inflamm Bowel Dis. 2001;7:271-275.
-
(2001)
Inflamm Bowel Dis
, vol.7
, pp. 271-275
-
-
Cho, J.H.1
-
9
-
-
53149144667
-
ATG16L1 T300A shows strong associations with disease subgroups in a large Australian IBD population: Further support for significant disease heterogeneity
-
Fowler EV, Doecke JD, Simms LA, et al. ATG16L1 T300A shows strong associations with disease subgroups in a large Australian IBD population: further support for significant disease heterogeneity. Am J Gastroenterol. 2008;103:2519-2526.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 2519-2526
-
-
Fowler, E.V.1
Doecke, J.D.2
Simms, L.A.3
-
10
-
-
44349136821
-
Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
-
Fisher SA, Tremelling M, Anderson CA, et al. Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease. Nat Genet. 2008;40:710-712.
-
(2008)
Nat Genet
, vol.40
, pp. 710-712
-
-
Fisher, S.A.1
Tremelling, M.2
Anderson, C.A.3
-
11
-
-
58949097704
-
Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
-
Anderson CA, Massey DC, Barrett JC, et al. Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology. 2009;136:523-529 e3.
-
(2009)
Gastroenterology
, vol.136
-
-
Anderson, C.A.1
Massey, D.C.2
Barrett, J.C.3
-
12
-
-
80655149205
-
New IBD genetics: Common pathways with other diseases
-
Lees CW, Barrett JC, Parkes M, et al. New IBD genetics: common pathways with other diseases. Gut. 2011;60:1739-1753.
-
(2011)
Gut
, vol.60
, pp. 1739-1753
-
-
Lees, C.W.1
Barrett, J.C.2
Parkes, M.3
-
13
-
-
34547176642
-
Unravelling the pathogenesis of inflammatory bowel disease
-
Xavier RJ, Podolsky DK. Unravelling the pathogenesis of inflammatory bowel disease. Nature. 2007;448:427-434.
-
(2007)
Nature
, vol.448
, pp. 427-434
-
-
Xavier, R.J.1
Podolsky, D.K.2
-
14
-
-
44349173654
-
Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis
-
Franke A, Balschun T, Karlsen TH, et al. Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis. Nat Genet. 2008;40:713-715.
-
(2008)
Nat Genet
, vol.40
, pp. 713-715
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
-
15
-
-
55049111426
-
Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility
-
Franke A, Balschun T, Karlsen TH, et al. Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility. Nat Genet. 2008;40:1319-1323.
-
(2008)
Nat Genet
, vol.40
, pp. 1319-1323
-
-
Franke, A.1
Balschun, T.2
Karlsen, T.H.3
-
16
-
-
79955763301
-
Validation in genetic association studies
-
König IR. Validation in genetic association studies. Brief Bioinform. 2010; 12:253-258.
-
(2010)
Brief Bioinform
, vol.12
, pp. 253-258
-
-
König, I.R.1
-
17
-
-
38749106156
-
European evidence-based consensus on the diagnosis and management of ulcerative colitis: Definitions and diagnosis
-
Stange EF, Travis SPL, Vermeire S, et al. European evidence-based consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis. J Crohn's Colitis. 2007;2:1-23.
-
(2007)
J Crohn's Colitis
, vol.2
, pp. 1-23
-
-
Stange, E.F.1
Travis, S.P.L.2
Vermeire, S.3
-
18
-
-
77957834845
-
KCNN4 gene variant is associated with ileal Crohn's disease in the Australian and New Zealand population
-
Simms LA, Doecke JD, Roberts RL, et al. KCNN4 gene variant is associated with ileal Crohn's disease in the Australian and New Zealand population. Am J Gastroenterol. 2010;105:2209-2217.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 2209-2217
-
-
Simms, L.A.1
Doecke, J.D.2
Roberts, R.L.3
-
19
-
-
84876386176
-
-
Accessed 2 August 2011
-
MassARRAY® iPLEX® Gold - SNP Genotyping. http://www.sequenom.com/ getdoc/197b98fa-93f7-40e8-9deb-a8dcfecf899e/iPLEX-brochure-web/Accessed 2 August 2011.
-
MassARRAY® IPLEX® Gold - SNP Genotyping
-
-
-
20
-
-
84870647022
-
-
Accessed 4 August 2011
-
UCSC Genome Browser. http://genome.ucsc.edu/Accessed 4 August 2011.
-
UCSC Genome Browser
-
-
-
21
-
-
80054123822
-
-
Accessed 4 August 2011
-
dpSNP Short Genetic Variations. http://www.ncbi.nlm.nih.gov/snp. Accessed 4 August 2011.
-
DpSNP Short Genetic Variations
-
-
-
22
-
-
84872809389
-
-
Accessed 4 August 2011
-
KEGG PATHWAY Database. http://www.genome.jp/kegg/pathway.html/Accessed 4 August 2011.
-
KEGG PATHWAY Database
-
-
-
24
-
-
61649103106
-
-
Version 5.0. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration
-
Review Manager (RevMan) (Computer program). Version 5.0. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2008.
-
(2008)
Review Manager (RevMan) (Computer Program)
-
-
-
26
-
-
0030969522
-
Regulation of interleukin-10 gene expression: Possible mechanisms accounting for its upregulation and for maturational differences in its expression by blood mononuclear cells
-
Le T, Leung L, Carroll WL, et al. Regulation of interleukin-10 gene expression: possible mechanisms accounting for its upregulation and for maturational differences in its expression by blood mononuclear cells. Blood. 1997;89:4112-4119.
-
(1997)
Blood
, vol.89
, pp. 4112-4119
-
-
Le, T.1
Leung, L.2
Carroll, W.L.3
-
27
-
-
0034235224
-
Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region
-
Powell MJ, Thompson SAJ, Tone Y, et al. Posttranscriptional regulation of IL-10 gene expression through sequences in the 3'-untranslated region. J Immunol. 2000;165:292-296.
-
(2000)
J Immunol
, vol.165
, pp. 292-296
-
-
Powell, M.J.1
Thompson, S.A.J.2
Tone, Y.3
-
28
-
-
29144501467
-
Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism
-
Németh ZH, Lutz CS, Csóka B, et al. Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanism. J Immunol. 2005;175:8260-8270.
-
(2005)
J Immunol.
, vol.175
, pp. 8260-8270
-
-
Németh, Z.H.1
Lutz, C.S.2
Csóka, B.3
-
29
-
-
48749106928
-
Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed nonlymphoid human tissues
-
Fruci D, Giacomini P, Nicotra MR, et al. Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed nonlymphoid human tissues. J Cell Physiol. 2008;216:742-749.
-
(2008)
J Cell Physiol
, vol.216
, pp. 742-749
-
-
Fruci, D.1
Giacomini, P.2
Nicotra, M.R.3
-
30
-
-
27644579993
-
Review: Immune surveillance of intracellular pathogens via autophagy
-
Schmid D, Münz C. Review: immune surveillance of intracellular pathogens via autophagy. Cell Death Differ. 2005;12:1519-1527.
-
(2005)
Cell Death Differ
, vol.12
, pp. 1519-1527
-
-
Schmid, D.1
Münz, C.2
-
31
-
-
33845699409
-
Novel KIND1 gene mutation in Kindler syndrome with severe gastrointestinal tract involvement
-
Sadler E, Klausegger A, Muss W, et al. Novel KIND1 gene mutation in Kindler syndrome with severe gastrointestinal tract involvement. Arch Dermatol. 2006;142:1619-1624.
-
(2006)
Arch Dermatol
, vol.142
, pp. 1619-1624
-
-
Sadler, E.1
Klausegger, A.2
Muss, W.3
-
32
-
-
36749051854
-
Chronic colitis due to an epithelial barrier defect: The role of kindlin-1 isoforms
-
Kern JS, Herz C, Haan E, et al. Chronic colitis due to an epithelial barrier defect: the role of kindlin-1 isoforms. J Pathol. 2007;213:462-470.
-
(2007)
J Pathol.
, vol.213
, pp. 462-470
-
-
Kern, J.S.1
Herz, C.2
Haan, E.3
-
33
-
-
33747681604
-
The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity
-
Li X, Thyssen G, Beliakoff J, et al. The novel PIAS-like protein hZimp10 enhances Smad transcriptional activity. J Biol Chem. 2006; 281:23748-23756.
-
(2006)
J Biol Chem
, vol.281
, pp. 23748-23756
-
-
Li, X.1
Thyssen, G.2
Beliakoff, J.3
|