Lipid domains in the milk fat globule membrane: Dynamics investigated in situ in milk in relation to temperature and time

Food Chemistry

Volumn 220, Issue , 2017, Pages 352-361

  Et Thakafy, Oumaima ^a   Guyomarc'h, Fanny ^a   Lopez, Christelle ^a  

^a AGROCAMPUS OUEST   (France)

Author keywords

Cholesterol; Confocal microscopy; Lipid phase transition; Phase separation; Sphingomyelin

Indexed keywords

CHOLESTEROL; CONFOCAL MICROSCOPY; OILS AND FATS; PHASE SEPARATION; PHOSPHOLIPIDS;

FUNCTIONAL PROPERTIES; INTERFACIAL PROPERTY; LIPID COMPOSITION; LIPID PHASE TRANSITIONS; LIPID REORGANIZATION; MILK FAT GLOBULES; SPHINGOMYELIN; STRUCTURAL INVESTIGATION;

DAIRY PRODUCTS;

CHOLESTEROL; MILK FAT; SPHINGOMYELIN; GLYCOLIPID; GLYCOPROTEIN; MILK FAT GLOBULE;

ARTICLE; BOVINE; CHEMICAL ANALYSIS; CONFOCAL MICROSCOPY; DIFFUSION; GAS CHROMATOGRAPHY; LIGHT SCATTERING; LIPID COMPOSITION; MILK; PHASE SEPARATION; SHEEP; STORAGE; TEMPERATURE; ANIMAL; CHEMISTRY; GOAT; METABOLISM; TIME FACTOR;

ANIMALS; CATTLE; CHOLESTEROL; GLYCOLIPIDS; GLYCOPROTEINS; GOATS; MICROSCOPY, CONFOCAL; MILK; SHEEP; SPHINGOMYELINS; TEMPERATURE; TIME FACTORS;

EID: 84991577817     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2016.10.017     Document Type: Article

References (43)

1. Bagatolli, L.A., Gratton, E., Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures. Biophysical Journal 78 (2000), 290–305.
2. Baumgart, T., Hunt, G., Farkas, E.R., Webb, W.W., Feigenson, G.W., Fluorescence probe partitioning between Lo/Ld phases in lipid membranes. Biochimica et Biophysica Acta (BBA) – Biomembranes 1768:9 (2007), 2182–2194.
3. Beales, P.A., Gordon, V.D., Zhao, Z., Egelhaaf, S.U., Poon, W.C.K., Solid-like domains in fluid membranes. Journal of Physics: Condensed Matter 17:45 (2005), S3341–S3346.
4. Blanchette, C.D., Orme, C.A., Ratto, T.V., Longo, M.L., Quantifying growth of symmetric and asymmetric lipid bilayer domains. Langmuir 24:4 (2008), 1219–1224.
5. Chemin, C., Bourgaux, C., Péan, J.-M., Pabst, G., Wüthrich, P., Couvreur, P., et al. Consequences of ions and pH on the supramolecular organization of sphingomyelin and sphingomyelin/cholesterol bilayers. Chemistry and Physics of Lipids 153:2 (2008), 119–129.
6. Chen, D., Santore, M.M., 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC)-rich domain formation in binary phospholipid vesicle membranes: Two-dimensional nucleation and growth. Langmuir 30:31 (2014), 9484–9493.
7. Cicuta, P., Keller, S.L., Veatch, S.L., Diffusion of liquid domains in lipid bilayer membranes. J. Phys. Chem. B 111:13 (2007), 3328–3331.
8. Deeth, H., The role of phospholipids in the stability of milk fat globules. Australian Journal of Dairy Technology, 52(1), 1997, 44.
9. Dewettinck, K., Rombaut, R., Thienpont, N., Le, T.T., Messens, K., Van Camp, J., Nutritional and technological aspects of milk fat globule membrane material. International Dairy Journal 18:5 (2008), 436–457.
10. Evers, J.M., Haverkamp, R.G., Holroyd, S.E., Jameson, G.B., Mackenzie, D.D.S., McCarthy, O.J., Heterogeneity of milk fat globule membrane structure and composition as observed using fluorescence microscopy techniques. International Dairy Journal 18:12 (2008), 1081–1089.
11. Frolov, V.A.J., Chizmadzhev, Y.A., Cohen, F.S., Zimmerberg, J., “Entropic traps” in the kinetics of phase separation in multicomponent membranes stabilize nanodomains. Biophysical Journal 91:1 (2006), 189–205.
12. Gallier, S., Gragson, D., Jiménez-Flores, R., Everett, D., Using confocal laser scanning microscopy to probe the milk fat gglobule membrane and associated proteins. Journal of Agricultural and Food Chemistry 58:7 (2010), 4250–4257.
13. Gallier, S., Vocking, K., Post, J.A., Van De Heijning, B., Acton, D., Van Der Beek, E.M., et al. A novel infant milk formula concept: Mimicking the human milk fat globule structure. Colloids and Surfaces B: Biointerfaces 136 (2015), 329–339.
14. Gómez-Cortés, P., Viturro, E., Juárez, M., de la Fuente, M.A., Alternative to decrease cholesterol in sheep milk cheeses. Food Chemistry 188 (2015), 325–327.
15. Heid, H.W., Keenan, T.W., Intracellular origin and secretion of milk fat globules. European Journal of Cell Biology 84:2–3 (2005), 245–258.
16. International Dairy Federation (2008) Milk – Determination of fat content – Gerber butyrometers, IDF 105:2008, IDF Editions, Brussels, Belgium (also available as: International Standard Organization ISO 488:2008).
17. International Standard Organization (2014) Determination of individual and total sterols contents – Gas chromatographic method – Part 1: Animal and vegetable fats and oils, NF EN ISO 12228-1, AFNOR Editions, La Plaine Saint-Denis, France.
18. Jenness, R., Composition and characteristics of goat milk: Review 1968–1979. Journal of Dairy Science 63:10 (1980), 1605–1630.
19. Jensen, R., Newburg, D., Bovine milk lipids. Handbook of milk composition, 1995, Academic press, New York, 260–267.
20. Lopez, C., Milk fat globules enveloped by their biological membrane: Unique colloidal assemblies with a specific composition and structure. Current Opinion in Colloid & Interface Science 16:5 (2011), 391–404.
21. Lopez, C., Bourgaux, C., Lesieur, P., Ollivon, M., Coupling of time-resolved synchrotron X-ray diffraction and DSC to elucidate the crystallisation properties and polymorphism of triglycerides in milk fat globules. Le Lait 87:4–5 (2007), 459–480.
22. Lopez, C., Briard-Bion, V., Ménard, O., Polar lipids, sphingomyelin and long-chain unsaturated fatty acids from the milk fat globule membrane are increased in milks produced by cows fed fresh pasture based diet during spring. Food Research International 58 (2014), 59–68.
23. Lopez, C., Cauty, C., Guyomarc'h, F., Organization of lipids in milks, infant milk formulas and various dairy products: Role of technological processes and potential impacts. Dairy Science & Technology 95:6 (2015), 863–893.
24. Lopez, C., Madec, M.-N., Jiménez-Flores, R., Lipid rafts in the bovine milk fat globule membrane revealed by the lateral segregation of phospholipids and heterogeneous distribution of glycoproteins. Food Chemistry 120:1 (2010), 22–33.
25. Lopez, C., Ménard, O., Human milk fat globules: Polar lipid composition and in situ structural investigations revealing the heterogeneous distribution of proteins and the lateral segregation of sphingomyelin in the biological membrane. Colloids and Surfaces B: Biointerfaces 83:1 (2011), 29–41.
26. Ménard, O., Ahmad, S., Rousseau, F., Briard-Bion, V., Gaucheron, F., Lopez, C., Buffalo vs. cow milk fat globules: Size distribution, zeta-potential, compositions in total fatty acids and in polar lipids from the milk fat globule membrane. Food Chemistry 120:2 (2010), 544–551.
27. Mesilati-Stahy, R., Argov-Argaman, N., The relationship between size and lipid composition of the bovine milk fat globule is modulated by lactation stage. Food Chemistry 145 (2014), 562–570.
28. Mullin, J., Crystallization. 4th ed., 2001, Butterworth-Heinemann, London.
29. Murthy, A.V.R., Guyomarc'h, F., Lopez, C., The temperature-dependent physical state of polar lipids and their miscibility impact the topography and mechanical properties of bilayer models of the milk fat globule membrane. Biochimica et Biophysica Acta (BBA) – Biomembranes 1858:9 (2016), 2181–2190.
30. Murthy, A.V.R., Guyomarc'h, F., Lopez, C., Cholesterol decreases the size and the mechanical resistance to rupture of sphingomyelin rich domains, in lipid bilayers studied as a model of the milk fat globule membrane. Langmuir 32:26 (2016), 6757–6765.
31. Murthy, A.V.R., Guyomarc'h, F., Paboeuf, G., Vié, V., Lopez, C., Cholesterol strongly affects the organization of lipid monolayers studied as models of the milk fat globule membrane: Condensing effect and change in the lipid domain morphology. Biochimica et Biophysica Acta (BBA) – Biomembranes 1848:10 (2015), 2308–2316.
32. Nguyen, H.T.H., Madec, M.-N., Ong, L., Kentish, S.E., Gras, S.L., Lopez, C., The dynamics of the biological membrane surrounding the buffalo milk fat globule investigated as a function of temperature. Food Chemistry 204 (2016), 343–351.
33. Nguyen, H.T.H., Ong, L., Beaucher, E., Madec, M.-N., Kentish, S.E., Gras, S.L., et al. Buffalo milk fat globules and their biological membrane: In situ structural investigations. Food Research International 67 (2015), 35–43.
34. Raison, J.K., Roberts, J.K., Berry, J.A., Correlations between the thermal stability of chloroplast (thylakoid) membranes and the composition and fluidity of their polar lipids upon acclimation of the higher plant, Nerium oleander, to growth temperature. Biochimica et Biophysica Acta (BBA) – Biomembranes 688 (1982), 218–228.
35. Sánchez-Juanes, F., Alonso, J.M., Zancada, L., Hueso, P., Distribution and fatty acid content of phospholipids from bovine milk and bovine milk fat globule membranes. International Dairy Journal 19:5 (2009), 273–278.
36. Simons, K., Vaz, W.L.C., Model systems, lipid rafts, and cell membranes. Annual Review of Biophysics and Biomolecular Structure 33:1 (2004), 269–295.
37. Szmodis, A.W., Blanchette, C.D., Longo, M.L., Orme, C.A., Parikh, A.N., Thermally induced phase separation in supported bilayers of glycosphingolipid and phospholipid mixtures. Biointerphases, 5(4), 2010, 120.
38. Veatch, S.L., Keller, S.L., Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol. Biophysical Journal 85:5 (2003), 3074–3083.
39. Wooding, F.B.P., Kemp, P., Ultrastructure of the milk fat globule membrane with and without triglyceride. Cell and Tissue Research 165 (1975), 113–127.
40. Zancada, L., Pérez-Díez, F., Sánchez-Juanes, F., Alonso, J.M., García-Pardo, L.A., Hueso, P., Phospholipid classes and fatty acid composition of ewe's and goat's milk. Grasas y Aceites 64:3 (2013), 304–310.
41. Zheng, H., Jiménez-Flores, R., Gragson, D., Everett, D.W., Phospholipid architecture of the bovine milk fat globule membrane using giant unilamellar vesicles as a model. Journal of Agricultural and Food Chemistry 62 (2014), 3236–3243.
42. Zou, X.-Q., Guo, Z., Huang, J.-H., Jin, Q.-Z., Cheong, L.-Z., Wang, X.-G., et al. Human milk fat globules from different stages of lactation: A lipid composition analysis and microstructure characterization. Journal of Agricultural and Food Chemistry 60:29 (2012), 7158–7167.
43. Zou, X., Guo, Z., Jin, Q., Huang, J., Cheong, L., Xu, X., et al. Composition and microstructure of colostrum and mature bovine milk fat globule membrane. Food Chemistry 185 (2015), 362–370.