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Volumn 79, Issue , 2016, Pages 451-461

The ubiquitin-like modifier FAT10 in cancer development

Author keywords

Carcinogenesis; FAT10; Inflammation; UBD; Ubiquitin proteasome system

Indexed keywords

BETA CATENIN; CHEMOKINE RECEPTOR CXCR4; CHEMOKINE RECEPTOR CXCR7; FAT10; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; MAJOR HISTOCOMPATIBILITY ANTIGEN; PROTEIN MAD2; PROTEIN P53; PROTEIN P62; SMAD2 PROTEIN; STAT3 PROTEIN; TUMOR NECROSIS FACTOR; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 84991571453     PISSN: 13572725     EISSN: 18785875     Source Type: Journal    
DOI: 10.1016/j.biocel.2016.07.001     Document Type: Review
Times cited : (62)

References (105)
  • 1
    • 0036782277 scopus 로고    scopus 로고
    • Deregulated homeobox gene expression in cancer: cause or consequence?
    • Abate-Shen, C., Deregulated homeobox gene expression in cancer: cause or consequence?. Nat. Rev. Cancer 2:10 (2002), 777–785.
    • (2002) Nat. Rev. Cancer , vol.2 , Issue.10 , pp. 777-785
    • Abate-Shen, C.1
  • 3
    • 84872199305 scopus 로고    scopus 로고
    • The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation
    • Aichem, A., Kalveram, B., Spinnenhirn, V., Kluge, K., Catone, N., Johansen, T., Groettrup, M., The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. J. Cell Sci. 125 (2012), 4576–4585.
    • (2012) J. Cell Sci. , vol.125 , pp. 4576-4585
    • Aichem, A.1    Kalveram, B.2    Spinnenhirn, V.3    Kluge, K.4    Catone, N.5    Johansen, T.6    Groettrup, M.7
  • 4
    • 84897533879 scopus 로고    scopus 로고
    • Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1
    • Aichem, A., Catone, N., Groettrup, M., Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1. FEBS J. 281:7 (2014), 1848–1859.
    • (2014) FEBS J. , vol.281 , Issue.7 , pp. 1848-1859
    • Aichem, A.1    Catone, N.2    Groettrup, M.3
  • 5
    • 0036571011 scopus 로고    scopus 로고
    • Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway
    • Amit, S., Hatzubai, A., Birman, Y., Andersen, J.S., Ben-Shushan, E., Mann, M., Ben-Neriah, Y., Alkalay, I., Axin-mediated CKI phosphorylation of beta-catenin at Ser 45: a molecular switch for the Wnt pathway. Genes Dev. 16:9 (2002), 1066–1076.
    • (2002) Genes Dev. , vol.16 , Issue.9 , pp. 1066-1076
    • Amit, S.1    Hatzubai, A.2    Birman, Y.3    Andersen, J.S.4    Ben-Shushan, E.5    Mann, M.6    Ben-Neriah, Y.7    Alkalay, I.8
  • 6
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill, F., Tumour necrosis factor and cancer. Nat. Rev. Cancer 9:5 (2009), 361–371.
    • (2009) Nat. Rev. Cancer , vol.9 , Issue.5 , pp. 361-371
    • Balkwill, F.1
  • 9
    • 84929493726 scopus 로고    scopus 로고
    • Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation
    • Bialas, J., Groettrup, M., Aichem, A., Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation. PLoS One, 3, 2015, e0120329.
    • (2015) PLoS One , vol.3 , pp. e0120329
    • Bialas, J.1    Groettrup, M.2    Aichem, A.3
  • 10
    • 84937228085 scopus 로고    scopus 로고
    • Silibinin and STAT3: a natural way of targeting transcription factors for cancer therapy
    • Bosch-Barrera, J., Menendez, J.A., Silibinin and STAT3: a natural way of targeting transcription factors for cancer therapy. Cancer Treat. Rev. 41:6 (2015), 540–546.
    • (2015) Cancer Treat. Rev. , vol.41 , Issue.6 , pp. 540-546
    • Bosch-Barrera, J.1    Menendez, J.A.2
  • 11
    • 84945152099 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 is selectively expressed in medullary thymic epithelial cells and modifies T cell selection
    • Buerger, S., Herrmann, V.L., Mundt, S., Trautwein, N., Groettrup, M., Basler, M., The ubiquitin-like modifier FAT10 is selectively expressed in medullary thymic epithelial cells and modifies T cell selection. J. Immunol. 195:9 (2015), 4106–4116.
    • (2015) J. Immunol. , vol.195 , Issue.9 , pp. 4106-4116
    • Buerger, S.1    Herrmann, V.L.2    Mundt, S.3    Trautwein, N.4    Groettrup, M.5    Basler, M.6
  • 14
    • 78651321769 scopus 로고    scopus 로고
    • The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention
    • Chen, D., Dou, Q.P., The ubiquitin-proteasome system as a prospective molecular target for cancer treatment and prevention. Curr. Protein Pept. Sci. 11:6 (2010), 459–470.
    • (2010) Curr. Protein Pept. Sci. , vol.11 , Issue.6 , pp. 459-470
    • Chen, D.1    Dou, Q.P.2
  • 15
    • 84894280603 scopus 로고    scopus 로고
    • Recombinant adenovirus encoding FAT10 small interfering RNA inhibits HCC growth in vitro and in vivo
    • Chen, J., Yang, L., Chen, H., Yuan, T., Liu, M., Chen, P., Recombinant adenovirus encoding FAT10 small interfering RNA inhibits HCC growth in vitro and in vivo. Exp. Mol. Pathol. 96:2 (2014), 207–211.
    • (2014) Exp. Mol. Pathol. , vol.96 , Issue.2 , pp. 207-211
    • Chen, J.1    Yang, L.2    Chen, H.3    Yuan, T.4    Liu, M.5    Chen, P.6
  • 16
    • 34748884321 scopus 로고    scopus 로고
    • E1-L2 activates both ubiquitin and FAT10
    • Chiu, Y.H., Sun, Q., Chen, Z.J., E1-L2 activates both ubiquitin and FAT10. Mol. Cell 27:6 (2007), 1014–1023.
    • (2007) Mol. Cell , vol.27 , Issue.6 , pp. 1014-1023
    • Chiu, Y.H.1    Sun, Q.2    Chen, Z.J.3
  • 17
    • 84899493959 scopus 로고    scopus 로고
    • NFkappaB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53
    • Choi, Y., Kim, J.K., Yoo, J.Y., NFkappaB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53. Mol. Oncol. 8:3 (2014), 642–655.
    • (2014) Mol. Oncol. , vol.8 , Issue.3 , pp. 642-655
    • Choi, Y.1    Kim, J.K.2    Yoo, J.Y.3
  • 18
    • 0019508071 scopus 로고
    • Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system
    • Ciechanover, A., Heller, H., Katz-Etzion, R., Hershko, A., Activation of the heat-stable polypeptide of the ATP-dependent proteolytic system. Proc. Natl. Acad. Sci. U. S. A. 78:2 (1981), 761–765.
    • (1981) Proc. Natl. Acad. Sci. U. S. A. , vol.78 , Issue.2 , pp. 761-765
    • Ciechanover, A.1    Heller, H.2    Katz-Etzion, R.3    Hershko, A.4
  • 19
    • 0032535483 scopus 로고    scopus 로고
    • The ubiquitin-proteasome pathway: on protein death and cell life
    • Ciechanover, A., The ubiquitin-proteasome pathway: on protein death and cell life. EMBO J. 17:24 (1998), 7151–7160.
    • (1998) EMBO J. , vol.17 , Issue.24 , pp. 7151-7160
    • Ciechanover, A.1
  • 20
    • 84953332302 scopus 로고    scopus 로고
    • Upregulation of p-Smad2 contributes to FAT10-induced oncogenic activities in glioma
    • (in press)
    • Dai, B., Zhang, Y., Zhang, P., Pan, C., Xu, C., Wan, W., Wu, Z., Zhang, J., Zhang, L., Upregulation of p-Smad2 contributes to FAT10-induced oncogenic activities in glioma. Tumour Biol., 2016, 10.1007/s13277-015-4739-6 (in press).
    • (2016) Tumour Biol.
    • Dai, B.1    Zhang, Y.2    Zhang, P.3    Pan, C.4    Xu, C.5    Wan, W.6    Wu, Z.7    Zhang, J.8    Zhang, L.9
  • 22
    • 59649085296 scopus 로고    scopus 로고
    • Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system
    • Ebstein, F., Lange, N., Urban, S., Seifert, U., Kruger, E., Kloetzel, P.M., Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system. Int. J. Biochem. Cell Biol. 41:5 (2009), 1205–1215.
    • (2009) Int. J. Biochem. Cell Biol. , vol.41 , Issue.5 , pp. 1205-1215
    • Ebstein, F.1    Lange, N.2    Urban, S.3    Seifert, U.4    Kruger, E.5    Kloetzel, P.M.6
  • 23
    • 84864337803 scopus 로고    scopus 로고
    • The FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation
    • Ebstein, F., Lehmann, A., Kloetzel, P.M., The FAT10- and ubiquitin-dependent degradation machineries exhibit common and distinct requirements for MHC class I antigen presentation. Cell Mol. Life Sci. CMLS 69:14 (2012), 2443–2454.
    • (2012) Cell Mol. Life Sci. CMLS , vol.69 , Issue.14 , pp. 2443-2454
    • Ebstein, F.1    Lehmann, A.2    Kloetzel, P.M.3
  • 24
    • 0029882886 scopus 로고    scopus 로고
    • Identification of seven new human MHC class I region genes around the HLA-F locus
    • Fan, W., Cai, W., Parimoo, S., Schwarz, D.C., Lennon, G.G., Weissman, S.M., Identification of seven new human MHC class I region genes around the HLA-F locus. Immunogenetics 44:2 (1996), 97–103.
    • (1996) Immunogenetics , vol.44 , Issue.2 , pp. 97-103
    • Fan, W.1    Cai, W.2    Parimoo, S.3    Schwarz, D.C.4    Lennon, G.G.5    Weissman, S.M.6
  • 25
    • 84971281668 scopus 로고    scopus 로고
    • Glioma genomics and epigenomics: arriving at the start and knowing it for the first time
    • Filbin, M.G., Suva, M.L., Glioma genomics and epigenomics: arriving at the start and knowing it for the first time. Annu. Rev. Pathol. 11 (2016), 497–521.
    • (2016) Annu. Rev. Pathol. , vol.11 , pp. 497-521
    • Filbin, M.G.1    Suva, M.L.2
  • 26
    • 65649115267 scopus 로고    scopus 로고
    • Recognition and processing of ubiquitin-protein conjugates by the proteasome
    • Finley, D., Recognition and processing of ubiquitin-protein conjugates by the proteasome. Annu. Rev. Biochem. 78 (2009), 477–513.
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 477-513
    • Finley, D.1
  • 28
    • 77950841093 scopus 로고    scopus 로고
    • Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling
    • French, S.W., Oliva, J., French, B.A., Li, J., Bardag-Gorce, F., Alcohol, nutrition and liver cancer: role of Toll-like receptor signaling. World J. Gastroenterol. 16:11 (2010), 1344–1348.
    • (2010) World J. Gastroenterol. , vol.16 , Issue.11 , pp. 1344-1348
    • French, S.W.1    Oliva, J.2    French, B.A.3    Li, J.4    Bardag-Gorce, F.5
  • 29
    • 77952304593 scopus 로고    scopus 로고
    • Pancreatic stellate cells increase the invasion of human pancreatic cancer cells through the stromal cell-derived factor-1/CXCR4 axis
    • Gao, Z., Wang, X., Wu, K., Zhao, Y., Hu, G., Pancreatic stellate cells increase the invasion of human pancreatic cancer cells through the stromal cell-derived factor-1/CXCR4 axis. Pancreatology 10:2-3 (2010), 186–193.
    • (2010) Pancreatology , vol.10 , Issue.2-3 , pp. 186-193
    • Gao, Z.1    Wang, X.2    Wu, K.3    Zhao, Y.4    Hu, G.5
  • 30
    • 84898609403 scopus 로고    scopus 로고
    • FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells
    • Gao, Y., Theng, S.S., Zhuo, J., Teo, W.B., Ren, J., Lee, C.G., FAT10, an ubiquitin-like protein, confers malignant properties in non-tumorigenic and tumorigenic cells. Carcinogenesis 35:4 (2014), 923–934.
    • (2014) Carcinogenesis , vol.35 , Issue.4 , pp. 923-934
    • Gao, Y.1    Theng, S.S.2    Zhuo, J.3    Teo, W.B.4    Ren, J.5    Lee, C.G.6
  • 31
    • 84982824733 scopus 로고    scopus 로고
    • Silibinin down-regulates FAT10 and modulate TNF-alpha/IFN-gamma-induced chromosomal instability and apoptosis sensitivity
    • Gao, Y., Theng, S.S., Mah, W.C., Lee, C.G., Silibinin down-regulates FAT10 and modulate TNF-alpha/IFN-gamma-induced chromosomal instability and apoptosis sensitivity. Biol. Open 4:8 (2015), 961–969.
    • (2015) Biol. Open , vol.4 , Issue.8 , pp. 961-969
    • Gao, Y.1    Theng, S.S.2    Mah, W.C.3    Lee, C.G.4
  • 34
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov, S.I., Greten, F.R., Karin, M., Immunity, inflammation, and cancer. Cell 140:6 (2010), 883–899.
    • (2010) Cell , vol.140 , Issue.6 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 35
    • 43849088209 scopus 로고    scopus 로고
    • Activating the ubiquitin family: UBA6 challenges the field
    • Groettrup, M., Pelzer, C., Schmidtke, G., Hofmann, K., Activating the ubiquitin family: UBA6 challenges the field. Trends Biochem. Sci. 33:5 (2008), 230–237.
    • (2008) Trends Biochem. Sci. , vol.33 , Issue.5 , pp. 230-237
    • Groettrup, M.1    Pelzer, C.2    Schmidtke, G.3    Hofmann, K.4
  • 36
    • 34547160807 scopus 로고    scopus 로고
    • Cloning and characterization of a gene encoding the human putative ubiquitin conjugating enzyme E2Z (UBE2Z)
    • Gu, X., Zhao, F., Zheng, M., Fei, X., Chen, X., Huang, S., Xie, Y., Mao, Y., Cloning and characterization of a gene encoding the human putative ubiquitin conjugating enzyme E2Z (UBE2Z). Mol. Biol. Rep. 34:3 (2007), 183–188.
    • (2007) Mol. Biol. Rep. , vol.34 , Issue.3 , pp. 183-188
    • Gu, X.1    Zhao, F.2    Zheng, M.3    Fei, X.4    Chen, X.5    Huang, S.6    Xie, Y.7    Mao, Y.8
  • 37
    • 80051709190 scopus 로고    scopus 로고
    • Inflammation and p53: a tale of two stresses
    • Gudkov, A.V., Gurova, K.V., Komarova, E.A., Inflammation and p53: a tale of two stresses. Genes Cancer 2:4 (2011), 503–516.
    • (2011) Genes Cancer , vol.2 , Issue.4 , pp. 503-516
    • Gudkov, A.V.1    Gurova, K.V.2    Komarova, E.A.3
  • 38
    • 27144529182 scopus 로고    scopus 로고
    • Ubiquitylation and cell signaling
    • Haglund, K., Dikic, I., Ubiquitylation and cell signaling. EMBO J. 24:19 (2005), 3353–3359.
    • (2005) EMBO J. , vol.24 , Issue.19 , pp. 3353-3359
    • Haglund, K.1    Dikic, I.2
  • 39
    • 84936937296 scopus 로고    scopus 로고
    • High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer
    • Han, T., Liu, Z., Li, H., Xie, W., Zhang, R., Zhu, L., Guo, F., Han, Y., Sheng, Y., Xie, X., High expression of UBD correlates with epirubicin resistance and indicates poor prognosis in triple-negative breast cancer. Onco Targets Ther. 8 (2015), 1643–1649.
    • (2015) Onco Targets Ther. , vol.8 , pp. 1643-1649
    • Han, T.1    Liu, Z.2    Li, H.3    Xie, W.4    Zhang, R.5    Zhu, L.6    Guo, F.7    Han, Y.8    Sheng, Y.9    Xie, X.10
  • 41
    • 84859136834 scopus 로고    scopus 로고
    • Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells
    • Heinrich, E.L., Lee, W., Lu, J., Lowy, A.M., Kim, J., Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells. J. Transl. Med., 10, 2012, 68.
    • (2012) J. Transl. Med. , vol.10 , pp. 68
    • Heinrich, E.L.1    Lee, W.2    Lu, J.3    Lowy, A.M.4    Kim, J.5
  • 42
    • 17644376207 scopus 로고    scopus 로고
    • FAT10, a ubiquitin- independent signal for proteasomal degradation
    • Hipp, M.S., Kalveram, B., Raasi, S., Groettrup, M., Schmidtke, G., FAT10, a ubiquitin- independent signal for proteasomal degradation. Mol. Cell. Biol. 25:9 (2005), 3483–3491.
    • (2005) Mol. Cell. Biol. , vol.25 , Issue.9 , pp. 3483-3491
    • Hipp, M.S.1    Kalveram, B.2    Raasi, S.3    Groettrup, M.4    Schmidtke, G.5
  • 43
    • 63649113699 scopus 로고    scopus 로고
    • Origin and function of ubiquitin-like proteins
    • Hochstrasser, M., Origin and function of ubiquitin-like proteins. Nature 458:7237 (2009), 422–429.
    • (2009) Nature , vol.458 , Issue.7237 , pp. 422-429
    • Hochstrasser, M.1
  • 44
    • 84880869807 scopus 로고    scopus 로고
    • The complexity of NF-kappaB signaling in inflammation and cancer
    • Hoesel, B., Schmid, J.A., The complexity of NF-kappaB signaling in inflammation and cancer. Mol. Cancer, 12, 2013, 86.
    • (2013) Mol. Cancer , vol.12 , pp. 86
    • Hoesel, B.1    Schmid, J.A.2
  • 46
    • 67650166084 scopus 로고    scopus 로고
    • FAT10 level in human gastric cancer and its relation with mutant p53 level, lymph node metastasis and TNM staging
    • Ji, F., Jin, X., Jiao, C.H., Xu, Q.W., Wang, Z.W., Chen, Y.L., FAT10 level in human gastric cancer and its relation with mutant p53 level, lymph node metastasis and TNM staging. World J. Gastroenterol. 15:18 (2009), 2228–2233.
    • (2009) World J. Gastroenterol. , vol.15 , Issue.18 , pp. 2228-2233
    • Ji, F.1    Jin, X.2    Jiao, C.H.3    Xu, Q.W.4    Wang, Z.W.5    Chen, Y.L.6
  • 47
    • 34347329214 scopus 로고    scopus 로고
    • Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging
    • Jin, J., Li, X., Gygi, S.P., Harper, J.W., Dual E1 activation systems for ubiquitin differentially regulate E2 enzyme charging. Nature 447:7148 (2007), 1135–1138.
    • (2007) Nature , vol.447 , Issue.7148 , pp. 1135-1138
    • Jin, J.1    Li, X.2    Gygi, S.P.3    Harper, J.W.4
  • 48
    • 59349096934 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition
    • Kalveram, B., Schmidtke, G., Groettrup, M., The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition. J. Cell Sci. 121:Pt 24 (2008), 4079–4088.
    • (2008) J. Cell Sci. , vol.121 , pp. 4079-4088
    • Kalveram, B.1    Schmidtke, G.2    Groettrup, M.3
  • 49
    • 84867530190 scopus 로고    scopus 로고
    • TGF beta signaling and its role in glioma pathogenesis
    • Kaminska, B., Kocyk, M., Kijewska, M., TGF beta signaling and its role in glioma pathogenesis. Adv. Exp. Med. Biol. 986 (2013), 171–187.
    • (2013) Adv. Exp. Med. Biol. , vol.986 , pp. 171-187
    • Kaminska, B.1    Kocyk, M.2    Kijewska, M.3
  • 50
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-kappaB in cancer development and progression
    • Karin, M., Nuclear factor-kappaB in cancer development and progression. Nature 441:7092 (2006), 431–436.
    • (2006) Nature , vol.441 , Issue.7092 , pp. 431-436
    • Karin, M.1
  • 51
    • 75449087368 scopus 로고    scopus 로고
    • Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors
    • Katoh, M., Katoh, M., Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors. Int. J. Oncol. 36:2 (2010), 415–420.
    • (2010) Int. J. Oncol. , vol.36 , Issue.2 , pp. 415-420
    • Katoh, M.1    Katoh, M.2
  • 52
  • 53
    • 0035827621 scopus 로고    scopus 로고
    • NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression
    • Kito, K., Yeh, E.T., Kamitani, T., NUB1, a NEDD8-interacting protein, is induced by interferon and down-regulates the NEDD8 expression. J. Biol. Chem. 276:23 (2001), 20603–20609.
    • (2001) J. Biol. Chem. , vol.276 , Issue.23 , pp. 20603-20609
    • Kito, K.1    Yeh, E.T.2    Kamitani, T.3
  • 56
    • 0038192327 scopus 로고    scopus 로고
    • Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
    • Lee, C.G., Ren, J., Cheong, I.S., Ban, K.H., Ooi, L.L., Yong Ta, n.S., Kan, A., Nuchprayoon, I., Jin, R., Lee, K.H., Choti, M., Lee, L.A., Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers. Oncogene 22:17 (2003), 2592–2603.
    • (2003) Oncogene , vol.22 , Issue.17 , pp. 2592-2603
    • Lee, C.G.1    Ren, J.2    Cheong, I.S.3    Ban, K.H.4    Ooi, L.L.5    Yong Ta, N.S.6    Kan, A.7    Nuchprayoon, I.8    Jin, R.9    Lee, K.H.10    Choti, M.11    Lee, L.A.12
  • 58
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J., p53, the cellular gatekeeper for growth and division. Cell 88:3 (1997), 323–331.
    • (1997) Cell , vol.88 , Issue.3 , pp. 323-331
    • Levine, A.J.1
  • 61
    • 34248198793 scopus 로고    scopus 로고
    • FAT10, a gene up-regulated in various cancers, is cell-cycle regulated
    • Lim, C.B., Zhang, D., Lee, C.G., FAT10, a gene up-regulated in various cancers, is cell-cycle regulated. Cell Div., 1, 2006, 20.
    • (2006) Cell Div. , vol.1 , pp. 20
    • Lim, C.B.1    Zhang, D.2    Lee, C.G.3
  • 62
    • 0033551210 scopus 로고    scopus 로고
    • A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2
    • Liu, Y.C., Pan, J., Zhang, C., Fan, W., Collinge, M., Bender, J.R., Weissman, S.M., A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. Proc. Natl. Acad. Sci. U. S. A. 96:8 (1999), 4313–4318.
    • (1999) Proc. Natl. Acad. Sci. U. S. A. , vol.96 , Issue.8 , pp. 4313-4318
    • Liu, Y.C.1    Pan, J.2    Zhang, C.3    Fan, W.4    Collinge, M.5    Bender, J.R.6    Weissman, S.M.7
  • 63
    • 84894047658 scopus 로고    scopus 로고
    • As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3beta pathway
    • Liu, L., Dong, Z., Liang, J., Cao, C., Sun, J., Ding, Y., Wu, D., As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3beta pathway. Oncogene 33:7 (2014), 909–920.
    • (2014) Oncogene , vol.33 , Issue.7 , pp. 909-920
    • Liu, L.1    Dong, Z.2    Liang, J.3    Cao, C.4    Sun, J.5    Ding, Y.6    Wu, D.7
  • 65
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: navigating downstream
    • Manning, B.D., Cantley, L.C., AKT/PKB signaling: navigating downstream. Cell 129:7 (2007), 1261–1274.
    • (2007) Cell , vol.129 , Issue.7 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 66
    • 84874771475 scopus 로고    scopus 로고
    • Profiling of ubiquitin-like modifications reveals features of mitotic control
    • Merbl, Y., Refour, P., Patel, H., Springer, M., Kirschner, M.W., Profiling of ubiquitin-like modifications reveals features of mitotic control. Cell 152:5 (2013), 1160–1172.
    • (2013) Cell , vol.152 , Issue.5 , pp. 1160-1172
    • Merbl, Y.1    Refour, P.2    Patel, H.3    Springer, M.4    Kirschner, M.W.5
  • 67
    • 34247333444 scopus 로고    scopus 로고
    • The spindle-assembly checkpoint in space and time
    • Musacchio, A., Salmon, E.D., The spindle-assembly checkpoint in space and time. Nat. Rev. Mol. Cell Biol. 8:5 (2007), 379–393.
    • (2007) Nat. Rev. Mol. Cell Biol. , vol.8 , Issue.5 , pp. 379-393
    • Musacchio, A.1    Salmon, E.D.2
  • 68
    • 79952043062 scopus 로고    scopus 로고
    • Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad
    • Nejak-Bowen, K.N., Monga, S.P., Beta-catenin signaling, liver regeneration and hepatocellular cancer: sorting the good from the bad. Semin. Cancer Biol. 21:1 (2011), 44–58.
    • (2011) Semin. Cancer Biol. , vol.21 , Issue.1 , pp. 44-58
    • Nejak-Bowen, K.N.1    Monga, S.P.2
  • 69
    • 84961784072 scopus 로고    scopus 로고
    • Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform
    • Nguyen, N.T., Now, H., Kim, W.J., Kim, N., Yoo, J.Y., Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform. Sci. Rep., 6, 2016, 23377.
    • (2016) Sci. Rep. , vol.6 , pp. 23377
    • Nguyen, N.T.1    Now, H.2    Kim, W.J.3    Kim, N.4    Yoo, J.Y.5
  • 73
    • 0033895709 scopus 로고    scopus 로고
    • Wnt signaling and cancer
    • Polakis, P., Wnt signaling and cancer. Genes Dev. 14:15 (2000), 1837–1851.
    • (2000) Genes Dev. , vol.14 , Issue.15 , pp. 1837-1851
    • Polakis, P.1
  • 75
    • 78650703048 scopus 로고    scopus 로고
    • Increased expression of FAT10 in colon benign, premalignant and malignant epithelial neoplasms
    • Qing, X., French, B.A., Oliva, J., French, S.W., Increased expression of FAT10 in colon benign, premalignant and malignant epithelial neoplasms. Exp. Mol. Pathol. 90:1 (2011), 51–54.
    • (2011) Exp. Mol. Pathol. , vol.90 , Issue.1 , pp. 51-54
    • Qing, X.1    French, B.A.2    Oliva, J.3    French, S.W.4
  • 76
    • 0032709801 scopus 로고    scopus 로고
    • A ubiquitin-like protein which is synergistically inducible by interferon-gamma and tumor necrosis factor-alpha
    • Raasi, S., Schmidtke, G., de Giuli, R., Groettrup, M., A ubiquitin-like protein which is synergistically inducible by interferon-gamma and tumor necrosis factor-alpha. Eur. J. Immunol. 29:12 (1999), 4030–4036.
    • (1999) Eur. J. Immunol. , vol.29 , Issue.12 , pp. 4030-4036
    • Raasi, S.1    Schmidtke, G.2    de Giuli, R.3    Groettrup, M.4
  • 77
    • 0035929607 scopus 로고    scopus 로고
    • The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis
    • Raasi, S., Schmidtke, G., Groettrup, M., The ubiquitin-like protein FAT10 forms covalent conjugates and induces apoptosis. J. Biol. Chem. 276:38 (2001), 35334–35343.
    • (2001) J. Biol. Chem. , vol.276 , Issue.38 , pp. 35334-35343
    • Raasi, S.1    Schmidtke, G.2    Groettrup, M.3
  • 78
    • 84859175458 scopus 로고    scopus 로고
    • FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis
    • Rani, N., Aichem, A., Schmidtke, G., Kreft, S.G., Groettrup, M., FAT10 and NUB1L bind to the VWA domain of Rpn10 and Rpn1 to enable proteasome-mediated proteolysis. Nat. Commun., 3, 2012, 749.
    • (2012) Nat. Commun. , vol.3 , pp. 749
    • Rani, N.1    Aichem, A.2    Schmidtke, G.3    Kreft, S.G.4    Groettrup, M.5
  • 80
    • 81355161184 scopus 로고    scopus 로고
    • FAT10 mediates the effect of TNF-alpha in inducing chromosomal instability
    • Ren, J., Wang, Y., Gao, Y., Mehta, S.B., Lee, C.G., FAT10 mediates the effect of TNF-alpha in inducing chromosomal instability. J. Cell Sci. 124:Pt 21 (2011), 3665–3675.
    • (2011) J. Cell Sci. , vol.124 , pp. 3665-3675
    • Ren, J.1    Wang, Y.2    Gao, Y.3    Mehta, S.B.4    Lee, C.G.5
  • 81
    • 67650620318 scopus 로고    scopus 로고
    • Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
    • Reyes-Turcu, F.E., Ventii, K.H., Wilkinson, K.D., Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu. Rev. Biochem. 78 (2009), 363–397.
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 363-397
    • Reyes-Turcu, F.E.1    Ventii, K.H.2    Wilkinson, K.D.3
  • 83
    • 84866152551 scopus 로고    scopus 로고
    • Stable antigen is most effective for eliciting CD8+ T-cell responses after DNA vaccination and infection with recombinant vaccinia virus in vivo
    • Schliehe, C., Bitzer, A., van den Broek, M., Groettrup, M., Stable antigen is most effective for eliciting CD8+ T-cell responses after DNA vaccination and infection with recombinant vaccinia virus in vivo. J. Virol. 86:18 (2012), 9782–9793.
    • (2012) J. Virol. , vol.86 , Issue.18 , pp. 9782-9793
    • Schliehe, C.1    Bitzer, A.2    van den Broek, M.3    Groettrup, M.4
  • 84
    • 33746023341 scopus 로고    scopus 로고
    • The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10
    • Schmidtke, G., Kalveram, B., Weber, E., Bochtler, P., Lukasiak, S., Hipp, M.S., Groettrup, M., The UBA domains of NUB1L are required for binding but not for accelerated degradation of the ubiquitin-like modifier FAT10. J. Biol. Chem. 281:29 (2006), 20045–20054.
    • (2006) J. Biol. Chem. , vol.281 , Issue.29 , pp. 20045-20054
    • Schmidtke, G.1    Kalveram, B.2    Weber, E.3    Bochtler, P.4    Lukasiak, S.5    Hipp, M.S.6    Groettrup, M.7
  • 85
    • 58649086714 scopus 로고    scopus 로고
    • Degradation of FAT10 by the 26S proteasome is independent of ubiquitylation but relies on NUB1L
    • Schmidtke, G., Kalveram, B., Groettrup, M., Degradation of FAT10 by the 26S proteasome is independent of ubiquitylation but relies on NUB1L. FEBS Lett. 583:3 (2009), 591–594.
    • (2009) FEBS Lett. , vol.583 , Issue.3 , pp. 591-594
    • Schmidtke, G.1    Kalveram, B.2    Groettrup, M.3
  • 86
    • 84890183307 scopus 로고    scopus 로고
    • FAT10ylation as a signal for proteasomal degradation
    • Schmidtke, G., Aichem, A., Groettrup, M., FAT10ylation as a signal for proteasomal degradation. Biochim. Biophys. Acta 1843:1 (2014), 97–102.
    • (2014) Biochim. Biophys. Acta , vol.1843 , Issue.1 , pp. 97-102
    • Schmidtke, G.1    Aichem, A.2    Groettrup, M.3
  • 87
    • 11144222544 scopus 로고    scopus 로고
    • Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance
    • Singh, R.P., Mallikarjuna, G.U., Sharma, G., Dhanalakshmi, S., Tyagi, A.K., Chan, D.C., Agarwal, C., Agarwal, R., Oral silibinin inhibits lung tumor growth in athymic nude mice and forms a novel chemocombination with doxorubicin targeting nuclear factor kappaB-mediated inducible chemoresistance. Clin. Cancer Res. 10:24 (2004), 8641–8647.
    • (2004) Clin. Cancer Res. , vol.10 , Issue.24 , pp. 8641-8647
    • Singh, R.P.1    Mallikarjuna, G.U.2    Sharma, G.3    Dhanalakshmi, S.4    Tyagi, A.K.5    Chan, D.C.6    Agarwal, C.7    Agarwal, R.8
  • 88
    • 70350325586 scopus 로고    scopus 로고
    • FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy
    • Snyder, A., Alsauskas, Z., Gong, P., Rosenstiel, P.E., Klotman, M.E., Klotman, P.E., Ross, M.J., FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. J. Virol. 83:22 (2009), 11983–11988.
    • (2009) J. Virol. , vol.83 , Issue.22 , pp. 11983-11988
    • Snyder, A.1    Alsauskas, Z.2    Gong, P.3    Rosenstiel, P.E.4    Klotman, M.E.5    Klotman, P.E.6    Ross, M.J.7
  • 89
    • 84911978547 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice
    • Spinnenhirn, V., Farhan, H., Basler, M., Aichem, A., Canaan, A., Groettrup, M., The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice. J. Cell Sci. 127:22 (2014), 4883–4893.
    • (2014) J. Cell Sci. , vol.127 , Issue.22 , pp. 4883-4893
    • Spinnenhirn, V.1    Farhan, H.2    Basler, M.3    Aichem, A.4    Canaan, A.5    Groettrup, M.6
  • 90
    • 84904768556 scopus 로고    scopus 로고
    • Increased FAT10 expression is related to poor prognosis in pancreatic ductal adenocarcinoma
    • Sun, G.H., Liu, Y.D., Yu, G., Li, N., Sun, X., Yang, J., Increased FAT10 expression is related to poor prognosis in pancreatic ductal adenocarcinoma. Tumour Biol. 35:6 (2014), 5167–5171.
    • (2014) Tumour Biol. , vol.35 , Issue.6 , pp. 5167-5171
    • Sun, G.H.1    Liu, Y.D.2    Yu, G.3    Li, N.4    Sun, X.5    Yang, J.6
  • 93
    • 84870425303 scopus 로고    scopus 로고
    • The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis
    • Tu, Y., Chen, C., Pan, J., Xu, J., Zhou, Z.G., Wang, C.Y., The Ubiquitin Proteasome Pathway (UPP) in the regulation of cell cycle control and DNA damage repair and its implication in tumorigenesis. Int. J. Clin. Exp. Pathol. 5:8 (2012), 726–738.
    • (2012) Int. J. Clin. Exp. Pathol. , vol.5 , Issue.8 , pp. 726-738
    • Tu, Y.1    Chen, C.2    Pan, J.3    Xu, J.4    Zhou, Z.G.5    Wang, C.Y.6
  • 94
    • 84866174563 scopus 로고    scopus 로고
    • Silibinin modulates TNF-alpha and IFN-gamma mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells
    • Tyagi, A., Agarwal, C., Dwyer-Nield, L.D., Singh, R.P., Malkinson, A.M., Agarwal, R., Silibinin modulates TNF-alpha and IFN-gamma mediated signaling to regulate COX2 and iNOS expression in tumorigenic mouse lung epithelial LM2 cells. Mol. Carcinog. 51:10 (2012), 832–842.
    • (2012) Mol. Carcinog. , vol.51 , Issue.10 , pp. 832-842
    • Tyagi, A.1    Agarwal, C.2    Dwyer-Nield, L.D.3    Singh, R.P.4    Malkinson, A.M.5    Agarwal, R.6
  • 95
    • 84942879344 scopus 로고    scopus 로고
    • STAT3 the oncogene—still eluding therapy?
    • Wake, M.S., Watson, C.J., STAT3 the oncogene—still eluding therapy?. FEBS J. 282:14 (2015), 2600–2611.
    • (2015) FEBS J. , vol.282 , Issue.14 , pp. 2600-2611
    • Wake, M.S.1    Watson, C.J.2
  • 96
    • 84874217880 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition (EMT) induced by TNF-alpha requires AKT/GSK-3beta-mediated stabilization of snail in colorectal cancer
    • Wang, H., Wang, H.S., Zhou, B.H., Li, C.L., Zhang, F., Wang, X.F., Zhang, G., Bu, X.Z., Cai, S.H., Du, J., Epithelial-mesenchymal transition (EMT) induced by TNF-alpha requires AKT/GSK-3beta-mediated stabilization of snail in colorectal cancer. PLoS One, 8(2), 2013, e56664.
    • (2013) PLoS One , vol.8 , Issue.2 , pp. e56664
    • Wang, H.1    Wang, H.S.2    Zhou, B.H.3    Li, C.L.4    Zhang, F.5    Wang, X.F.6    Zhang, G.7    Bu, X.Z.8    Cai, S.H.9    Du, J.10
  • 97
    • 84892948811 scopus 로고    scopus 로고
    • Emerging therapies targeting the ubiquitin proteasome system in cancer
    • Weathington, N.M., Mallampalli, R.K., Emerging therapies targeting the ubiquitin proteasome system in cancer. J. Clin. Invest. 124:1 (2014), 6–12.
    • (2014) J. Clin. Invest. , vol.124 , Issue.1 , pp. 6-12
    • Weathington, N.M.1    Mallampalli, R.K.2
  • 98
    • 84900397992 scopus 로고    scopus 로고
    • Mechanisms for regulating deubiquitinating enzymes
    • Wolberger, C., Mechanisms for regulating deubiquitinating enzymes. Prot. Sci. 23:4 (2014), 344–353.
    • (2014) Prot. Sci. , vol.23 , Issue.4 , pp. 344-353
    • Wolberger, C.1
  • 99
    • 63049125531 scopus 로고    scopus 로고
    • Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation
    • Xu, P., Duong, D.M., Seyfried, N.T., Cheng, D., Xie, Y., Robert, J., Rush, J., Hochstrasser, M., Finley, D., Peng, J., Quantitative proteomics reveals the function of unconventional ubiquitin chains in proteasomal degradation. Cell 137:1 (2009), 133–145.
    • (2009) Cell , vol.137 , Issue.1 , pp. 133-145
    • Xu, P.1    Duong, D.M.2    Seyfried, N.T.3    Cheng, D.4    Xie, Y.5    Robert, J.6    Rush, J.7    Hochstrasser, M.8    Finley, D.9    Peng, J.10
  • 100
    • 84868461025 scopus 로고    scopus 로고
    • Increased expression of FAT10 is correlated with progression and prognosis of human glioma
    • Yuan, J., Tu, Y., Mao, X., He, S., Wang, L., Fu, G., Zong, J., Zhang, Y., Increased expression of FAT10 is correlated with progression and prognosis of human glioma. Pathol. Oncol. Res. POR 18:4 (2012), 833–839.
    • (2012) Pathol. Oncol. Res. POR , vol.18 , Issue.4 , pp. 833-839
    • Yuan, J.1    Tu, Y.2    Mao, X.3    He, S.4    Wang, L.5    Fu, G.6    Zong, J.7    Zhang, Y.8
  • 101
    • 84907484229 scopus 로고    scopus 로고
    • Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying beta-catenin degradation
    • Yuan, R., Wang, K., Hu, J., Yan, C., Li, M., Yu, X., Liu, X., Lei, J., Guo, W., Wu, L., Hong, K., Shao, J., Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying beta-catenin degradation. Cancer Res. 74:18 (2014), 5287–5300.
    • (2014) Cancer Res. , vol.74 , Issue.18 , pp. 5287-5300
    • Yuan, R.1    Wang, K.2    Hu, J.3    Yan, C.4    Li, M.5    Yu, X.6    Liu, X.7    Lei, J.8    Guo, W.9    Wu, L.10    Hong, K.11    Shao, J.12
  • 102
    • 79960122931 scopus 로고    scopus 로고
    • Dual roles of immune cells and their factors in cancer development and progression
    • Zamarron, B.F., Chen, W., Dual roles of immune cells and their factors in cancer development and progression. Int. J. Biol. Sci. 7:5 (2011), 651–658.
    • (2011) Int. J. Biol. Sci. , vol.7 , Issue.5 , pp. 651-658
    • Zamarron, B.F.1    Chen, W.2
  • 103
    • 33646163921 scopus 로고    scopus 로고
    • p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers
    • Zhang, D.W., Jeang, K.T., Lee, C.G., p53 negatively regulates the expression of FAT10, a gene upregulated in various cancers. Oncogene 25:16 (2006), 2318–2327.
    • (2006) Oncogene , vol.25 , Issue.16 , pp. 2318-2327
    • Zhang, D.W.1    Jeang, K.T.2    Lee, C.G.3
  • 104
    • 84924762947 scopus 로고    scopus 로고
    • Ubiquitin D is an independent prognostic marker for survival in stage IIB-IIC colon cancer patients treated with 5-fluoruracil-based adjuvant chemotherapy
    • Zhao, S., Jiang, T., Tang, H., Cui, F., Liu, C., Guo, F., Lu, H., Xue, Y., Jiang, W., Peng, Z., Yan, D., Ubiquitin D is an independent prognostic marker for survival in stage IIB-IIC colon cancer patients treated with 5-fluoruracil-based adjuvant chemotherapy. J. Gastroenterol. Hepatol. 30:4 (2015), 680–688.
    • (2015) J. Gastroenterol. Hepatol. , vol.30 , Issue.4 , pp. 680-688
    • Zhao, S.1    Jiang, T.2    Tang, H.3    Cui, F.4    Liu, C.5    Guo, F.6    Lu, H.7    Xue, Y.8    Jiang, W.9    Peng, Z.10    Yan, D.11
  • 105
    • 77950654038 scopus 로고    scopus 로고
    • Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells
    • Zheng, K., Li, H.Y., Su, X.L., Wang, X.Y., Tian, T., Li, F., Ren, G.S., Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells. J. Exp. Clin. Cancer Res. CR, 29, 2010, 31.
    • (2010) J. Exp. Clin. Cancer Res. CR , vol.29 , pp. 31
    • Zheng, K.1    Li, H.Y.2    Su, X.L.3    Wang, X.Y.4    Tian, T.5    Li, F.6    Ren, G.S.7


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