-
2
-
-
84859259227
-
Histone ubiquitylation and chromatin dynamics
-
Wright DE, Wang CY, Kao CF (2012) Histone ubiquitylation and chromatin dynamics. Front Biosci 17:1051-1078
-
(2012)
Front Biosci
, vol.17
, pp. 1051-1078
-
-
Wright, D.E.1
Wang, C.Y.2
Kao, C.F.3
-
3
-
-
84876886904
-
Regulation of DNA damage responses by ubiquitin and SUMO
-
Jackson SP, Durocher D (2013) Regulation of DNA damage responses by ubiquitin and SUMO. Mol Cell 49:795-807
-
(2013)
Mol Cell
, vol.49
, pp. 795-807
-
-
Jackson, S.P.1
Durocher, D.2
-
4
-
-
80755132190
-
Endosomal transport via ubiquitination
-
Piper RC, Lehner PJ (2011) Endosomal transport via ubiquitination. Trends Cell Biol 21:647-655
-
(2011)
Trends Cell Biol
, vol.21
, pp. 647-655
-
-
Piper, R.C.1
Lehner, P.J.2
-
5
-
-
84875236362
-
Regulation of NF-kappaB by ubiquitination
-
Chen J, Chen ZJ (2013) Regulation of NF-kappaB by ubiquitination. Curr Opin Immunol 25:4-12
-
(2013)
Curr Opin Immunol
, vol.25
, pp. 4-12
-
-
Chen, J.1
Chen, Z.J.2
-
7
-
-
9744227183
-
Ubiquitin: Structures, functions, mechanisms
-
Pickart CM, Eddins MJ (2004) Ubiquitin: Structures, functions, mechanisms. Biochim Biophys Acta 1695:55-72
-
(2004)
Biochim Biophys Acta
, vol.1695
, pp. 55-72
-
-
Pickart, C.M.1
Eddins, M.J.2
-
8
-
-
33750219981
-
A ubiquitin ligase complex assembles linear polyubiquitin chains
-
Kirisako T, Kamei K, Murata S, Kato M, Fukumoto H, Kanie M, Sano S, Tokunaga F, Tanaka K, Iwai K( 2006) A ubiquitin ligase complex assembles linear polyubiquitin chains. EMBO J 25:4877-4887
-
(2006)
EMBO J
, vol.25
, pp. 4877-4887
-
-
Kirisako, T.1
Kamei, K.2
Murata, S.3
Kato, M.4
Fukumoto, H.5
Kanie, M.6
Sano, S.7
Tokunaga, F.8
Tanaka, K.9
Iwai, K.10
-
9
-
-
84879008640
-
Ube2W conjugates ubiquitin to alphaamino groups of protein N-termini
-
Tatham MH, Plechanovova A, Jaffray EG, Salmen H, Hay RT (2013) Ube2W conjugates ubiquitin to alphaamino groups of protein N-termini. Biochem J 453: 137-145
-
(2013)
Biochem J
, vol.453
, pp. 137-145
-
-
Tatham, M.H.1
Plechanovova, A.2
Jaffray, E.G.3
Salmen, H.4
Hay, R.T.5
-
10
-
-
1542344435
-
Proteasomes and their kin: Proteases in the machine age
-
Pickart CM, Cohen RE (2004) Proteasomes and their kin: Proteases in the machine age. Nat Rev Mol Cell Biol 5:177-187
-
(2004)
Nat Rev Mol Cell Biol
, vol.5
, pp. 177-187
-
-
Pickart, C.M.1
Cohen, R.E.2
-
11
-
-
0033525582
-
Noncanonical MMS2- encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair
-
Hofmann RM, Pickart CM (1999) Noncanonical MMS2- encoded ubiquitin-conjugating enzyme functions in assembly of novel polyubiquitin chains for DNA repair. Cell 96:645-653
-
(1999)
Cell
, vol.96
, pp. 645-653
-
-
Hofmann, R.M.1
Pickart, C.M.2
-
12
-
-
84880931087
-
Deubiquitylases from genes to organism
-
Clague MJ, Barsukov I, Coulson JM, Liu H, Rigden DJ, Urbe S (2013) Deubiquitylases from genes to organism. Physiol Rev 93:1289-1315
-
(2013)
Physiol Rev
, vol.93
, pp. 1289-1315
-
-
Clague, M.J.1
Barsukov, I.2
Coulson, J.M.3
Liu, H.4
Rigden, D.J.5
Urbe, S.6
-
14
-
-
55549120571
-
Polyubiquitylation of histone H2B
-
Geng F, Tansey WP (2008) Polyubiquitylation of histone H2B. Mol Biol Cell 19:3616-3624
-
(2008)
Mol Biol Cell
, vol.19
, pp. 3616-3624
-
-
Geng, F.1
Tansey, W.P.2
-
15
-
-
79955828987
-
Molecular mechanisms of ubiquitin-dependent membrane traffic
-
Hurley JH, Stenmark H (2011) Molecular mechanisms of ubiquitin-dependent membrane traffic. Annu Rev Biophys 40:119-142
-
(2011)
Annu Rev Biophys
, vol.40
, pp. 119-142
-
-
Hurley, J.H.1
Stenmark, H.2
-
16
-
-
78751498823
-
E2s: Structurally economical and functionally replete
-
Wenzel DM, Stoll KE, Klevit RE (2011) E2s: Structurally economical and functionally replete. Biochem J 433:31-42
-
(2011)
Biochem J
, vol.433
, pp. 31-42
-
-
Wenzel, D.M.1
Stoll, K.E.2
Klevit, R.E.3
-
19
-
-
68049084674
-
Breaking the chains: Structure and function of the deubiquitinases
-
Komander D, Clague MJ, Urbe S (2009) Breaking the chains: Structure and function of the deubiquitinases. Nat Rev Mol Cell Biol 10:550-563
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 550-563
-
-
Komander, D.1
Clague, M.J.2
Urbe, S.3
-
20
-
-
67650620318
-
Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes
-
Reyes-Turcu FE, Ventii KH, Wilkinson KD (2009) Regulation and cellular roles of ubiquitin-specific deubiquitinating enzymes. Annu Rev Biochem 78:363-397
-
(2009)
Annu Rev Biochem
, vol.78
, pp. 363-397
-
-
Reyes-Turcu, F.E.1
Ventii, K.H.2
Wilkinson, K.D.3
-
21
-
-
84890190983
-
Regulation of proteolysis by human deubiquitinating enzymes
-
Eletr ZM, Wilkinson KD (2014) Regulation of proteolysis by human deubiquitinating enzymes. Biochim Biophys Acta 1843:114-128
-
(2014)
Biochim Biophys Acta
, vol.1843
, pp. 114-128
-
-
Eletr, Z.M.1
Wilkinson, K.D.2
-
22
-
-
67649634849
-
Defining the human deubiquitinating enzyme interaction landscape
-
Sowa ME, Bennett EJ, Gygi SP, Harper JW (2009) Defining the human deubiquitinating enzyme interaction landscape. Cell 138:389-403
-
(2009)
Cell
, vol.138
, pp. 389-403
-
-
Sowa, M.E.1
Bennett, E.J.2
Gygi, S.P.3
Harper, J.W.4
-
23
-
-
79955941973
-
PTMs in conversation: Activity and function of deubiquitinating enzymes regulated via post-translational modifications
-
Kessler BM, Edelmann MJ (2011) PTMs in conversation: Activity and function of deubiquitinating enzymes regulated via post-translational modifications. Cell Biochem Biophys 60:21-38
-
(2011)
Cell Biochem Biophys
, vol.60
, pp. 21-38
-
-
Kessler, B.M.1
Edelmann, M.J.2
-
24
-
-
84875912087
-
Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells
-
Lee JG, Baek K, Soetandyo N, Ye Y (2013) Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells. Nat Commun 4:1568
-
(2013)
Nat Commun
, vol.4
, pp. 1568
-
-
Lee, J.G.1
Baek, K.2
Soetandyo, N.3
Ye, Y.4
-
25
-
-
84871699184
-
Deubiquitinases as a signaling target of oxidative stress
-
Cotto-Rios XM, Bekes M, Chapman J, Ueberheide B, Huang TT (2012) Deubiquitinases as a signaling target of oxidative stress. Cell Rep 2:1475-1484
-
(2012)
Cell Rep
, vol.2
, pp. 1475-1484
-
-
Cotto-Rios, X.M.1
Bekes, M.2
Chapman, J.3
Ueberheide, B.4
Huang, T.T.5
-
26
-
-
50949126350
-
Protein partners of deubiquitinating enzymes
-
Ventii KH, Wilkinson KD (2008) Protein partners of deubiquitinating enzymes. Biochem J 414:161-175
-
(2008)
Biochem J
, vol.414
, pp. 161-175
-
-
Ventii, K.H.1
Wilkinson, K.D.2
-
27
-
-
64149129169
-
UAF1 is a subunit of multiple deubiquitinating enzyme complexes
-
Cohn MA, Kee Y, Haas W, Gygi SP, D?Andrea AD( 2009) UAF1 is a subunit of multiple deubiquitinating enzyme complexes. J Biol Chem 284:5343-5351
-
(2009)
J Biol Chem
, vol.284
, pp. 5343-5351
-
-
Cohn, M.A.1
Kee, Y.2
Haas, W.3
Gygi, S.P.4
Dandrea, A.D.5
-
28
-
-
77955867565
-
Non-canonical inhibition of DNA damagedependent ubiquitination by OTUB1
-
Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O?Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D( 2010) Non-canonical inhibition of DNA damagedependent ubiquitination by OTUB1. Nature 466:941-946
-
(2010)
Nature
, vol.466
, pp. 941-946
-
-
Nakada, S.1
Tai, I.2
Panier, S.3
Al-Hakim, A.4
Iemura, S.5
Juang, Y.C.6
Odonnell, L.7
Kumakubo, A.8
Munro, M.9
Sicheri, F.10
Gingras, A.C.11
Natsume, T.12
Suda, T.13
Durocher, D.14
-
29
-
-
79956107843
-
Ubiquitin-specific proteases as cancer drug targets
-
Sippl W, Collura V, Colland F (2011) Ubiquitin-specific proteases as cancer drug targets. Future Oncol 7:619-632
-
(2011)
Future Oncol
, vol.7
, pp. 619-632
-
-
Sippl, W.1
Collura, V.2
Colland, F.3
-
30
-
-
0028674466
-
Catalytic mechanism in papain family of cysteine peptidases
-
Storer AC, Menard R (1994) Catalytic mechanism in papain family of cysteine peptidases. Methods Enzymol 244:486-500
-
(1994)
Methods Enzymol
, vol.244
, pp. 486-500
-
-
Storer, A.C.1
Menard, R.2
-
31
-
-
0037184947
-
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
-
Hu M, Li P, Li M, Li W, Yao T, Wu JW, Gu W, Cohen RE, Shi Y (2002) Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell 111:1041-1054
-
(2002)
Cell
, vol.111
, pp. 1041-1054
-
-
Hu, M.1
Li, P.2
Li, M.3
Li, W.4
Yao, T.5
Wu, J.W.6
Gu, W.7
Cohen, R.E.8
Shi, Y.9
-
32
-
-
61449120240
-
Structural basis and specificity of human otubain 1-mediated deubiquitination
-
Edelmann MJ, Iphofer A, Akutsu M, Altun M, di Gleria K, Kramer HB, Fiebiger E, Dhe-Paganon S, Kessler BM (2009) Structural basis and specificity of human otubain 1-mediated deubiquitination. Biochem J 418:379-390
-
(2009)
Biochem J
, vol.418
, pp. 379-390
-
-
Edelmann, M.J.1
Iphofer, A.2
Akutsu, M.3
Altun, M.4
Di Gleria, K.5
Kramer, H.B.6
Fiebiger, E.7
Dhe-Paganon, S.8
Kessler, B.M.9
-
33
-
-
84878862687
-
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin
-
Keusekotten K, Elliott PR, Glockner L, Fiil BK, Damgaard RB, Kulathu Y, Wauer T, Hospenthal MK, Gyrd-Hansen M, Krappmann D, Hofmann K, Komander D (2013) OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin. Cell 153:1312-1326
-
(2013)
Cell
, vol.153
, pp. 1312-1326
-
-
Keusekotten, K.1
Elliott, P.R.2
Glockner, L.3
Fiil, B.K.4
Damgaard, R.B.5
Kulathu, Y.6
Wauer, T.7
Hospenthal, M.K.8
Gyrd-Hansen, M.9
Krappmann, D.10
Hofmann, K.11
Komander, D.12
-
34
-
-
79955938866
-
The multifaceted roles of USP7: New therapeutic opportunities
-
Nicholson B, Suresh Kumar KG (2011) The multifaceted roles of USP7: New therapeutic opportunities. Cell Biochem Biophys 60:61-68
-
(2011)
Cell Biochem Biophys
, vol.60
, pp. 61-68
-
-
Nicholson, B.1
Suresh Kumar, K.G.2
-
35
-
-
0037061508
-
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization
-
Li M, Chen D, Shiloh A, Luo J, Nikolaev AY, Qin J, Gu W (2002) Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature 416: 648-653
-
(2002)
Nature
, vol.416
, pp. 648-653
-
-
Li, M.1
Chen, D.2
Shiloh, A.3
Luo, J.4
Nikolaev, A.Y.5
Qin, J.6
Gu, W.7
-
36
-
-
80053594090
-
Mechanism of USP7/ HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase
-
Faesen AC, Dirac AM, Shanmugham A, Ovaa H, Perrakis A, Sixma TK (2011) Mechanism of USP7/ HAUSP activation by its C-terminal ubiquitin-like domain and allosteric regulation by GMP-synthetase. Mol Cell 44:147-159
-
(2011)
Mol Cell
, vol.44
, pp. 147-159
-
-
Faesen, A.C.1
Dirac, A.M.2
Shanmugham, A.3
Ovaa, H.4
Perrakis, A.5
Sixma, T.K.6
-
38
-
-
84878832998
-
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis
-
Mevissen TE, Hospenthal MK, Geurink PP, Elliott PR, Akutsu M, Arnaudo N, Ekkebus R, Kulathu Y, Wauer T, El Oualid F, Freund SM, Ovaa H, Komander D( 2013) OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. Cell 154:169-184
-
(2013)
Cell
, vol.154
, pp. 169-184
-
-
Mevissen, T.E.1
Hospenthal, M.K.2
Geurink, P.P.3
Elliott, P.R.4
Akutsu, M.5
Arnaudo, N.6
Ekkebus, R.7
Kulathu, Y.8
Wauer, T.9
El Oualid, F.10
Freund, S.M.11
Ovaa, H.12
Komander, D.13
-
39
-
-
60149084572
-
Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1
-
Wang T, Yin L, Cooper EM, Lai MY, Dickey S, Pickart CM, Fushman D, Wilkinson KD, Cohen RE, Wolberger C (2009) Evidence for bidentate substrate binding as the basis for the K48 linkage specificity of otubain 1. J Mol Biol 386:1011-1023
-
(2009)
J Mol Biol
, vol.386
, pp. 1011-1023
-
-
Wang, T.1
Yin, L.2
Cooper, E.M.3
Lai, M.Y.4
Dickey, S.5
Pickart, C.M.6
Fushman, D.7
Wilkinson, K.D.8
Cohen, R.E.9
Wolberger, C.10
-
40
-
-
84880851215
-
OTULIN restricts Met1-linked ubiquitination to control innate immune signaling
-
Fiil BK, Damgaard RB, Wagner SA, Keusekotten K, Fritsch M, Bekker-Jensen S, Mailand N, Choudhary C, Komander D, Gyrd-Hansen M (2013) OTULIN restricts Met1-linked ubiquitination to control innate immune signaling. Mol Cell 50:818-830
-
(2013)
Mol Cell
, vol.50
, pp. 818-830
-
-
Fiil, B.K.1
Damgaard, R.B.2
Wagner, S.A.3
Keusekotten, K.4
Fritsch, M.5
Bekker-Jensen, S.6
Mailand, N.7
Choudhary, C.8
Komander, D.9
Gyrd-Hansen, M.10
-
41
-
-
84879390723
-
The linear ubiquitinspecific deubiquitinase gumby regulates angiogenesis
-
Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, Srikumar T, Huang H, Dunham WH, Fukumura R, Xie G, Gondo Y, Raught B, Gingras AC, Sicheri F, Cordes SP (2013) The linear ubiquitinspecific deubiquitinase gumby regulates angiogenesis. Nature 498:318-324
-
(2013)
Nature
, vol.498
, pp. 318-324
-
-
Rivkin, E.1
Almeida, S.M.2
Ceccarelli, D.F.3
Juang, Y.C.4
Maclean, T.A.5
Srikumar, T.6
Huang, H.7
Dunham, W.H.8
Fukumura, R.9
Xie, G.10
Gondo, Y.11
Raught, B.12
Gingras, A.C.13
Sicheri, F.14
Cordes, S.P.15
-
42
-
-
84875886251
-
Regulation of A20 and other OTU deubiquitinases by reversible oxidation
-
Kulathu Y, Garcia FJ, Mevissen TE, Busch M, Arnaudo N, Carroll KS, Barford D, Komander D (2013) Regulation of A20 and other OTU deubiquitinases by reversible oxidation. Nat Commun 4:1569
-
(2013)
Nat Commun
, vol.4
, pp. 1569
-
-
Kulathu, Y.1
Garcia, F.J.2
Mevissen, T.E.3
Busch, M.4
Arnaudo, N.5
Carroll, K.S.6
Barford, D.7
Komander, D.8
-
43
-
-
33749487778
-
The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11
-
Kohler A, Pascual-Garcia P, Llopis A, Zapater M, Posas F, Hurt E, Rodriguez-Navarro S (2006) The mRNA export factor Sus1 is involved in Spt/Ada/Gcn5 acetyltransferase-mediated H2B deubiquitinylation through its interaction with Ubp8 and Sgf11. Mol Biol Cell 17:4228-4236
-
(2006)
Mol Biol Cell
, vol.17
, pp. 4228-4236
-
-
Kohler, A.1
Pascual-Garcia, P.2
Llopis, A.3
Zapater, M.4
Posas, F.5
Hurt, E.6
Rodriguez-Navarro, S.7
-
46
-
-
44649179312
-
Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export
-
Kohler A, Schneider M, Cabal GG, Nehrbass U, Hurt E (2008) Yeast Ataxin-7 links histone deubiquitination with gene gating and mRNA export. Nat Cell Biol 10: 707-715
-
(2008)
Nat Cell Biol
, vol.10
, pp. 707-715
-
-
Kohler, A.1
Schneider, M.2
Cabal, G.G.3
Nehrbass, U.4
Hurt, E.5
-
47
-
-
68249105095
-
Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes
-
Lee KK, Swanson SK, Florens L, Washburn MP, Workman JL (2009) Yeast Sgf73/Ataxin-7 serves to anchor the deubiquitination module into both SAGA and Slik(SALSA) HAT complexes. Epigenetics Chromatin 2:2
-
(2009)
Epigenetics Chromatin
, vol.2
, pp. 2
-
-
Lee, K.K.1
Swanson, S.K.2
Florens, L.3
Washburn, M.P.4
Workman, J.L.5
-
48
-
-
77952519938
-
Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module
-
Kohler A, Zimmerman E, Schneider M, Hurt E, Zheng N (2010) Structural basis for assembly and activation of the heterotetrameric SAGA histone H2B deubiquitinase module. Cell 141:606-617
-
(2010)
Cell
, vol.141
, pp. 606-617
-
-
Kohler, A.1
Zimmerman, E.2
Schneider, M.3
Hurt, E.4
Zheng, N.5
-
49
-
-
77953060092
-
Structural insights into the assembly and function of the SAGA deubiquitinating module
-
Samara NL, Datta AB, Berndsen CE, Zhang X, Yao T, Cohen RE, Wolberger C (2010) Structural insights into the assembly and function of the SAGA deubiquitinating module. Science 328:1025-1029
-
(2010)
Science
, vol.328
, pp. 1025-1029
-
-
Samara, N.L.1
Datta, A.B.2
Berndsen, C.E.3
Zhang, X.4
Yao, T.5
Cohen, R.E.6
Wolberger, C.7
-
50
-
-
33646066025
-
The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin
-
Reyes-Turcu FE, Horton JR, Mullally JE, Heroux A, Cheng X, Wilkinson KD (2006) The ubiquitin binding domain ZnF UBP recognizes the C-terminal diglycine motif of unanchored ubiquitin. Cell 124:1197-1208
-
(2006)
Cell
, vol.124
, pp. 1197-1208
-
-
Reyes-Turcu, F.E.1
Horton, J.R.2
Mullally, J.E.3
Heroux, A.4
Cheng, X.5
Wilkinson, K.D.6
-
51
-
-
77950514403
-
Structural basis for the interaction between yeast saga complex components SGF11 and SUS1
-
Ellisdon AM, Jani D, Koehler A, Hurt E, Stewart M( 2009) Structural basis for the interaction between yeast saga complex components SGF11 and SUS1. J Biol Chem 285:3850-3856
-
(2009)
J Biol Chem
, vol.285
, pp. 3850-3856
-
-
Ellisdon, A.M.1
Jani, D.2
Koehler, A.3
Hurt, E.4
Stewart, M.5
-
52
-
-
27744516748
-
Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14
-
Hu M, Li P, Song L, Jeffrey PD, Chenova TA, Wilkinson KD, Cohen RE, Shi Y (2005) Structure and mechanisms of the proteasome-associated deubiquitinating enzyme USP14. EMBO J 24:3747-3756
-
(2005)
EMBO J
, vol.24
, pp. 3747-3756
-
-
Hu, M.1
Li, P.2
Song, L.3
Jeffrey, P.D.4
Chenova, T.A.5
Wilkinson, K.D.6
Cohen, R.E.7
Shi, Y.8
-
53
-
-
33846021632
-
Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8
-
Avvakumov GV, Walker JR, Xue S, Finerty PJ Jr, Mackenzie F, Newman EM, Dhe-Paganon S (2006) Amino-terminal dimerization, NRDP1-rhodanese interaction, and inhibited catalytic domain conformation of the ubiquitin-specific protease 8 (USP8). J Biol Chem 281:38061-38070
-
(2006)
J Biol Chem
, vol.281
, pp. 38061-38070
-
-
Avvakumov, G.V.1
Walker, J.R.2
Xue, S.3
Finerty Jr., P.J.4
Mackenzie, F.5
Newman, E.M.6
Dhe-Paganon, S.7
-
54
-
-
0023042522
-
Mechanism of ubiquitin carboxyl-terminal hydrolase. Borohydride and hydroxylamine inactivate in the presence of ubiquitin
-
Pickart CM, Rose IA (1986) Mechanism of ubiquitin carboxyl-terminal hydrolase. Borohydride and hydroxylamine inactivate in the presence of ubiquitin. J Biol Chem 261:10210-10217
-
(1986)
J Biol Chem
, vol.261
, pp. 10210-10217
-
-
Pickart, C.M.1
Rose, I.A.2
-
55
-
-
84864848052
-
A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity
-
Samara NL, Ringel AE, Wolberger C (2012) A role for intersubunit interactions in maintaining SAGA deubiquitinating module structure and activity. Structure 20:1414-1424
-
(2012)
Structure
, vol.20
, pp. 1414-1424
-
-
Samara, N.L.1
Ringel, A.E.2
Wolberger, C.3
-
56
-
-
80052597874
-
The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements
-
Lang G, Bonnet J, Umlauf D, Karmodiya K, Koffler J, Stierle M, Devys D, Tora L (2011) The tightly controlled deubiquitination activity of the human SAGA complex differentially modifies distinct gene regulatory elements. Mol Cell Biol 31:3734-3744
-
(2011)
Mol Cell Biol
, vol.31
, pp. 3734-3744
-
-
Lang, G.1
Bonnet, J.2
Umlauf, D.3
Karmodiya, K.4
Koffler, J.5
Stierle, M.6
Devys, D.7
Tora, L.8
-
57
-
-
72849149738
-
Crimean-Congo hemorrhagic fever virusencoded ovarian tumor protease activity is dispensable for virus RNA polymerase function
-
Bergeron E, Albarino CG, Khristova ML, Nichol ST( 2010) Crimean-Congo hemorrhagic fever virusencoded ovarian tumor protease activity is dispensable for virus RNA polymerase function. J Virol 84:216-226
-
(2010)
J Virol
, vol.84
, pp. 216-226
-
-
Bergeron, E.1
Albarino, C.G.2
Khristova, M.L.3
Nichol, S.T.4
-
58
-
-
84865677098
-
A census of human soluble protein complexes
-
Havugimana PC, Hart GT, Nepusz T, Yang H, Turinsky AL, Li Z, Wang PI, Boutz DR, Fong V, Phanse S, Babu M, Craig SA, Hu P, Wan C, Vlasblom J, Dar VU, Bezginov A, Clark GW, Wu GC, Wodak SJ, Tillier ER, Paccanaro A, Marcotte EM, Emili A (2012) A census of human soluble protein complexes. Cell 150: 1068-1081
-
(2012)
Cell
, vol.150
, pp. 1068-1081
-
-
Havugimana, P.C.1
Hart, G.T.2
Nepusz, T.3
Yang, H.4
Turinsky, A.L.5
Li, Z.6
Wang, P.I.7
Boutz, D.R.8
Fong, V.9
Phanse, S.10
Babu, M.11
Craig, S.A.12
Hu, P.13
Wan, C.14
Vlasblom, J.15
Dar, V.U.16
Bezginov, A.17
Clark, G.W.18
Wu, G.C.19
Wodak, S.J.20
Tillier, E.R.21
Paccanaro, A.22
Marcotte, E.M.23
Emili, A.24
more..
-
59
-
-
84883740585
-
E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1
-
Wiener R, DiBello AT, Lombardi PM, Guzzo CM, Zhang X, Matunis MJ, Wolberger C (2013) E2 ubiquitin-conjugating enzymes regulate the deubiquitinating activity of OTUB1. Nat Struct Mol Biol 20: 1033-1039
-
(2013)
Nat Struct Mol Biol
, vol.20
, pp. 1033-1039
-
-
Wiener, R.1
Dibello, A.T.2
Lombardi, P.M.3
Guzzo, C.M.4
Zhang, X.5
Matunis, M.J.6
Wolberger, C.7
-
60
-
-
84862806447
-
The mechanism of OTUB1-mediated inhibition of ubiquitination
-
Wiener R, Zhang X, Wang T, Wolberger C (2012) The mechanism of OTUB1-mediated inhibition of ubiquitination. Nature 483:618-622
-
(2012)
Nature
, vol.483
, pp. 618-622
-
-
Wiener, R.1
Zhang, X.2
Wang, T.3
Wolberger, C.4
-
61
-
-
84856801739
-
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function
-
Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF, Mateo AR, Pruneda JN, Mao DY, Szilard RK, Orlicky S, Munro M, Brzovic PS, Klevit RE, Sicheri F, Durocher D (2012) OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme function. Mol Cell 45:384-397
-
(2012)
Mol Cell
, vol.45
, pp. 384-397
-
-
Juang, Y.C.1
Landry, M.C.2
Sanches, M.3
Vittal, V.4
Leung, C.C.5
Ceccarelli, D.F.6
Mateo, A.R.7
Pruneda, J.N.8
Mao, D.Y.9
Szilard, R.K.10
Orlicky, S.11
Munro, M.12
Brzovic, P.S.13
Klevit, R.E.14
Sicheri, F.15
Durocher, D.16
-
62
-
-
84864386119
-
Molecular basis of Lys-63- linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13
-
Sato Y, Yamagata A, Goto-Ito S, Kubota K, Miyamoto R, Nakada S, Fukai S (2012) Molecular basis of Lys-63- linked polyubiquitination inhibition by the interaction between human deubiquitinating enzyme OTUB1 and ubiquitin- conjugating enzyme UBC13. J Biol Chem 287:25860-25868
-
(2012)
J Biol Chem
, vol.287
, pp. 25860-25868
-
-
Sato, Y.1
Yamagata, A.2
Goto-Ito, S.3
Kubota, K.4
Miyamoto, R.5
Nakada, S.6
Fukai, S.7
-
63
-
-
84876412379
-
OTUB1 modulates c-IAP1 stability to regulate signalling pathways
-
Goncharov T, Niessen K, de Almagro MC, Izrael- Tomasevic A, Fedorova AV, Varfolomeev E, Arnott D, Deshayes K, Kirkpatrick DS, Vucic D (2013) OTUB1 modulates c-IAP1 stability to regulate signalling pathways. EMBO J 32:1103-1114
-
(2013)
EMBO J
, vol.32
, pp. 1103-1114
-
-
Goncharov, T.1
Niessen, K.2
De Almagro, M.C.3
Izrael- Tomasevic, A.4
Fedorova, A.V.5
Varfolomeev, E.6
Arnott, D.7
Deshayes, K.8
Kirkpatrick, D.S.9
Vucic, D.10
-
64
-
-
0347756727
-
Two isoforms of otubain 1 regulate T cell anergy via GRAIL
-
Soares L, Seroogy C, Skrenta H, Anandasabapathy N, Lovelace P, Chung CD, Engleman E, Fathman CG( 2004) Two isoforms of otubain 1 regulate T cell anergy via GRAIL. Nat Immunol 5:45-54
-
(2004)
Nat Immunol
, vol.5
, pp. 45-54
-
-
Soares, L.1
Seroogy, C.2
Skrenta, H.3
Anandasabapathy, N.4
Lovelace, P.5
Chung, C.D.6
Engleman, E.7
Fathman, C.G.8
-
65
-
-
36749082959
-
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
-
Cohn MA, Kowal P, Yang K, Haas W, Huang TT, Gygi SP, D?Andrea AD (2007) A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway. Mol Cell 28:786-797
-
(2007)
Mol Cell
, vol.28
, pp. 786-797
-
-
Cohn, M.A.1
Kowal, P.2
Yang, K.3
Haas, W.4
Huang, T.T.5
Gygi, S.P.6
Dandrea, A.D.7
-
66
-
-
84883391069
-
The WD40- repeat protein-containing deubiquitinase complex: Catalysis, regulation, and potential for therapeutic intervention
-
Villamil MA, Liang Q, Zhuang Z (2013) The WD40- repeat protein-containing deubiquitinase complex: Catalysis, regulation, and potential for therapeutic intervention. Cell Biochem Biophys 67:111-126
-
(2013)
Cell Biochem Biophys
, vol.67
, pp. 111-126
-
-
Villamil, M.A.1
Liang, Q.2
Zhuang, Z.3
-
67
-
-
0030297912
-
Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin
-
Gaudet R, Bohm A, Sigler PB (1996) Crystal structure at 2.4 angstroms resolution of the complex of transducin betagamma and its regulator, phosducin. Cell 87: 577-588
-
(1996)
Cell
, vol.87
, pp. 577-588
-
-
Gaudet, R.1
Bohm, A.2
Sigler, P.B.3
-
68
-
-
0034660088
-
Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast
-
Sprague ER, Redd MJ, Johnson AD, Wolberger C( 2000) Structure of the C-terminal domain of Tup1, a corepressor of transcription in yeast. EMBO J 19: 3016-3027
-
(2000)
EMBO J
, vol.19
, pp. 3016-3027
-
-
Sprague, E.R.1
Redd, M.J.2
Johnson, A.D.3
Wolberger, C.4
-
69
-
-
84861380457
-
Deubiquitinases in cancer: New functions and therapeutic options
-
Fraile JM, Quesada V, Rodriguez D, Freije JM, Lopez- Otin C (2012) Deubiquitinases in cancer: New functions and therapeutic options. Oncogene 31:2373-2388
-
(2012)
Oncogene
, vol.31
, pp. 2373-2388
-
-
Fraile, J.M.1
Quesada, V.2
Rodriguez, D.3
Freije, J.M.4
Lopez-Otin, C.5
-
71
-
-
0031011721
-
Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution
-
Johnston SC, Larsen CN, Cook WJ, Wilkinson KD, Hill CP (1997) Crystal structure of a deubiquitinating enzyme (human UCH-L3) at 1.8 A resolution. EMBO J 16:3787-3796
-
(1997)
EMBO J
, vol.16
, pp. 3787-3796
-
-
Johnston, S.C.1
Larsen, C.N.2
Cook, W.J.3
Wilkinson, K.D.4
Hill, C.P.5
-
72
-
-
79953009529
-
Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity
-
Weeks SD, Grasty KC, Hernandez-Cuebas L, Loll PJ( 2011) Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity. J Biol Chem 286:4555-4565
-
(2011)
J Biol Chem
, vol.286
, pp. 4555-4565
-
-
Weeks, S.D.1
Grasty, K.C.2
Hernandez-Cuebas, L.3
Loll, P.J.4
-
73
-
-
19344364762
-
JAMM: A metalloprotease-like zinc site in the proteasome and signalosome
-
Ambroggio XI, Rees DC, Deshaies RJ (2004) JAMM: A metalloprotease-like zinc site in the proteasome and signalosome. PLoS Biol 2:E2
-
(2004)
PLoS Biol
, vol.2
-
-
Ambroggio, X.I.1
Rees, D.C.2
Deshaies, R.J.3
|