Chemokine receptor CXCR7 regulates the invasion, angiogenesis and tumor growth of human hepatocellular carcinoma cells

Journal of Experimental and Clinical Cancer Research

Volumn 29, Issue 1, 2010, Pages

  Zheng, Ke ^a   Li, Hong Yuan ^a   Su, Xin Liang ^a   Wang, Xiao Yi ^a   Tian, Tian ^a   Li, Fan ^a   Ren, Guo Sheng ^a  

^a CHONGQING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CHEMOKINE RECEPTOR CXCR6; CHEMOKINE RECEPTOR CXCR7; SHORT HAIRPIN RNA; STROMAL CELL DERIVED FACTOR 1; VASCULOTROPIN; CHEMOKINE RECEPTOR CXCR; CXCR7 PROTEIN, HUMAN; VASCULOTROPIN A;

ADULT; AGED; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INVASION; CARCINOGENICITY; CELL ADHESION; CELL DENSITY; CELL INVASION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; RNA INTERFERENCE; STABLE TRANSFECTION; TUMOR GROWTH; UPREGULATION; XENOGRAFT; ANIMAL; BIOSYNTHESIS; CANCER TRANSPLANTATION; LIVER TUMOR; METABOLISM; METHODOLOGY; MIDDLE AGED; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; TUMOR CELL LINE;

ADULT; AGED; ANIMALS; ANTIGENS, CD31; CARCINOMA, HEPATOCELLULAR; CELL ADHESION; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LIVER NEOPLASMS; MALE; MICE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; RECEPTORS, CXCR; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 77950654038     PISSN: None     EISSN: 17569966     Source Type: Journal    
DOI: 10.1186/1756-9966-29-31     Document Type: Article

References (35)

1. Prognostic molecular markers in hepatocellular carcinoma: a systematic review. CD Mann CP Neal G Garcea MM Manson AR Dennison DP Berry, Eur J Cancer 2007 43 6 979 92 (Pubitemid 46483030)
2. Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma. R Tung-Ping Poon ST Fan J Wong, Ann Surg 2000 232 1 10 24 (Pubitemid 30456545)
3. Involvement of chemokine receptors in breast cancer metastasis. A Müller B Homey H Soto N Ge D Catron ME Buchanan T McClanahan E Murphy W Yuan SN Wagner JL Barrera A Mohar E Verstegui A Zlotnik, Nature 2001 410 6824 50 6 (Pubitemid 32225831)
4. CXCR7 (RDC1) promotes breast and lung tumor growth in vivo and is expressed on tumor-associated vasculature. Z Miao KE Luker BC Summers R Berahovich MS Bhojani A Rehemtulla CG Kleer JJ Essner A Nasevicius GD Luker MC Howard TJ Schall, Proc Natl Acad Sci USA 2007 104 40 15735 40 (Pubitemid 350035369)
5. Stromal-Cell Derived Factor Is Expressed by Dendritic Cells and Endothelium in Human Skin. JL Pablos A Amara A Bouloc B Santiago A Caruz M Galindo T Delaunay JL Virelizier F Arenzana-Seisdedos, Am J Pathol 1999 155 5 1577 86
6. The chemokine SDF-1 is a cemoattractant for Human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of cd34+ progenitors to peripheralBlood. A Aiuti IJ Webb C Bleul T Springer JC Gutierrez-Ramos, J Exp Med 1997 185 1 111 20 (Pubitemid 27039446)
7. Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins. K Tashiro H Tada R Heilker M Shirozu T Nakano T Honjo, Science 1993 261 5121 600 3 (Pubitemid 23278369)
8. The molecular biology of leukocyte chemoattractant receptors. PM Murphy, Annu Rev Immunol 1994 12 593 633 (Pubitemid 24140426)
9. Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. T Nagasawa S Hirota K Tachibana N Takakura S Nishikawa Y Kitamura N Yoshida H Kikutani T Kishimoto, Nature 1996 382 6592 635 8 (Pubitemid 26268957)
10. Increased Survival, Proliferation, and Migration in Metastatic Human Pancreatic Tumor Cells Expressing Functional CXCR4. F Marchesi P Monti BE Leone A Zerbi A Vecchi L Piemonti A Mantovani P Allavena, Cancer Res 2004 64 22 8420 7 (Pubitemid 39491782)
11. Stromal Cell-Derived Factor-1/Chemokine (C-X-C Motif) Ligand 12 Stimulates Human Hepatoma Cell Growth, Migration, and Invasion. A Sutton V Friand S Brulé-Donneger T Chaigneau M Ziol O Sainte-Catherine A Poiré L Saffar M Kraemer J Vassy P Nahon JL Salzmann L Gattegno N Charnaux, Mol Cancer Res 2007 5 1 21 33 (Pubitemid 46246764)
12. The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tract. K Tachibana S Hirota H Iizasa H Yoshida K Kawabata Y Kataoka Y Kitamura K Matsushima N Yoshida S Nishikawa T Kishimoto T Nagasawa, Nature 1998 393 6685 591 4 (Pubitemid 28319250)
13. Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. YR Zou AH Kottmann M Kuroda I Taniuchi DR Littman, Nature 1998 393 6685 595 9 (Pubitemid 28319251)
14. Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone. RS Taichman C Cooper ET Keller KJ Pienta NS Taichman LK McCauley, Cancer Res 2002 62 6 1832 7 (Pubitemid 34408510)
15. Dissemination of hepatocellular carcinoma is mediated via chemokine receptor CXCR4. CC Schimanski R Bahre I Gockel A Müller K Frerichs V Hörner A Teufel N Simiantonaki S Biesterfeld T Wehler M Schuler T Achenbach T Junginger PR Galle M Moehler, Br J Cancer 2006 95 2 210 7 (Pubitemid 44050921)
16. Chemokines, chemokine receptors, and cancer metastasis. T Kakinuma ST Hwang, J Leukoc Biol 2006 79 4 639 51 (Pubitemid 44835596)
17. Upregulation of CXCR4 is essential for HER2-mediated tumor metastasis. YM Li Y Pan Y Wei X Cheng BP Zhou M Tan X Zhou W Xia GN Hortobagyi D Yu MC Hung, Cancer Cell 2004 6 5 459 69 (Pubitemid 39469982)
18. The bicyclam AMD3100 story. E De Clercq, Nat Rev Drug Discov 2003 2 7 581 7 (Pubitemid 37361749)
19. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. JM Burns BC Summers Y Wang A Melikian R Berahovich Z Miao ME Penfold MJ Sunshine DR Littman CJ Kuo K Wei BE McMaster K Wright MC Howard TJ Schall, J Exp Med 2006 203 9 2201 13 (Pubitemid 44352240)
20. Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas. K Grymula M Tarnowski M Wysoczynski J Drukala FG Barr J Ratajczak M Kucia MZ Ratajczak, Int J Cancer 2010
21. Elucidation of CXCR7-mediated signaling events and inhibition of CXCR4-mediated tumor cell transendothelial migration by CXCR7 ligands. BA Zabel Y Wang S Lewén RD Berahovich ME Penfold P Zhang J Powers BC Summers Z Miao B Zhao A Jalili A Janowska-Wieczorek JC Jaen TJ Schall, J Immunol 2009 183 5 3204 11
22. Essential but differential role for CXCR4 and CXCR7 in the therapeutic homingof human renal progenitor cells. B Mazzinghi E Ronconi E Lazzeri C Sagrinati L Ballerini ML Angelotti E Parente R Mancina GS Netti F Becherucci M Gacci M Carini L Gesualdo M Rotondi E Maggi L Lasagni M Serio S Romagnani P Romagnani, J Exp Med 2008 205 2 479 90 (Pubitemid 351281611)
23. Higher expression of chemokine receptor CXCR7 is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer. S Iwakiri N Mino T Takahashi M Sonobe S Nagai K Okubo H Wada H Date R Miyahara, Cancer 2009 115 11 2580 93
24. The Role of CXCR7/RDC1 as a Chemokine Receptor for CXCL12/SDF-1 in Prostate Cancer. J Wang Y Shiozawa J Wang Y Wang Y Jung KJ Pienta R Mehra R Loberg RS Taichman, J Biol Chem 2008 283 7 4283 94
25. High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma. R Maréchal P Demetter N Nagy A Berton C Decaestecker M Polus J Closset J Devière I Salmon JL Van Laethem, Br J Cancer 2009 100 9 1444 51
26. Effect of the chemokine receptor CXCR7 on proliferation of carcinoma cells in vitro and in vivo. J Meijer J Ogink E Roos, Br J Cancer 2008 99 9 1493 501
27. The CXCL12-CXCR4 chemotactic pathway as a target of adjuvant breast cancer therapies. RJ Epstein, Nat Rev Cancer 2004 4 11 901 9
28. Manipulating the chemokine-chemokine receptor network to treat cancer. PA Ruffini P Morandi N Cabioglu K Altundag M Cristofanilli, Cancer 2007 109 12 2392 404 (Pubitemid 46906457)
29. CXCR7, CXCR4 and CXCL12: An eccentric trio? M Thelen S Thelen, J Neuroimmunol 2008 198 1-2 9 13
30. AMD3100 Is a CXCR7 Ligand with Allosteric Agonist Properties. I Kalatskaya YA Berchiche S Gravel BJ Limberg JS Rosenbaum N Heveker, Mol Pharmacol 2009 75 5 1240 7
31. Angiogenesis in cancer, vascular, rheumatoid and other disease. J Folkman, Nat Med 1995 1 1 27 31
32. The SDF-1-CXCR4 Axis Stimulates VEGF Secretion and Activates Integrins but does not Affect Proliferation and Survival in Lymphohematopoietic Cells. J Kijowski M Baj-Krzyworzeka M Majka R Reca LA Marquez M Christofidou-Solomidou A Janowska-Wieczorek MZ Ratajczak, Stem Cells 2001 19 5 453 66 (Pubitemid 32900088)
33. Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. M Darash-Yahana E Pikarsky R Abramovitch E Zeira B Pal R Karplus K Beider S Avniel S Kasem E Galun A Peled, FASEB J 2004 18 11 1240 2 (Pubitemid 39561563)
34. VEGF and the quest for tumour angiogenesis factors. N Ferrara, Nat Rev Cancer 2002 2 10 795 803 (Pubitemid 37328914)
35. What is the evidence that tumors are angiogenesis dependent? J Folkman, J Natl Cancer Inst 1990 82 1 4 6 (Pubitemid 20020880)