Silibinin down-regulates FAT10 and modulate TNF-α/IFN-ã-induced chromosomal instability and apoptosis sensitivity

Biology Open

Volumn 4, Issue 8, 2015, Pages 961-969

  Gao, Yun ^a,e   Theng, Steven Setiawan ^b,c   Mah, Way Champ ^a,b   Lee, Caroline G L ^a,b,c,d  

^a DIVISION OF MEDICAL ONCOLOGY   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^d DUKE NUS MEDICAL SCHOOL   (Singapore)

^e He Eye Industry Group Co LTD   (China)

Author keywords

Apoptosis; Chromosomal instability; FAT10; IFN ; Silibinin; TNF

Indexed keywords

BETA GALACTOSIDASE; FAT10 PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN; RECOMBINANT GAMMA INTERFERON; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; SILIBININ; SMALL INTERFERING RNA; TRANSCRIPTOME; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING SITE; CANCER INHIBITION; CELL DEATH; CELL SURVIVAL; CHROMOSOMAL INSTABILITY; COLORECTAL CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEREGULATION; DOWN REGULATION; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVATION; ENZYME ACTIVITY; GENE EXPRESSION; GENE TRANSLOCATION; HCT116 CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IMMUNOMODULATION; MALE; MOUSE; NONHUMAN; NUDE MOUSE; PRIMARY TUMOR; PROMOTER REGION; TUMOR VOLUME; UPREGULATION;

EID: 84982824733     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.011189     Document Type: Article

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