메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Ubiquitin-like modifier FAT10 attenuates RIG-I mediated antiviral signaling by segregating activated RIG-I from its signaling platform

Author keywords

[No Author keywords available]

Indexed keywords

DDX58 PROTEIN, HUMAN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; IRF3 PROTEIN, HUMAN; RETINOIC ACID INDUCIBLE PROTEIN I; TRANSCRIPTION FACTOR; TRIM25 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBD PROTEIN, HUMAN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

EID: 84961784072     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep23377     Document Type: Article
Times cited : (42)

References (50)
  • 1
    • 3242813113 scopus 로고    scopus 로고
    • The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • Yoneyama, M. et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737 (2004).
    • (2004) Nat. Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1
  • 2
    • 79957597757 scopus 로고    scopus 로고
    • Mitochondria in innate immune responses. Nature reviews
    • West, A. P., Shadel, G. S., Ghosh, S. Mitochondria in innate immune responses. Nature reviews. Immunol. 11, 389-402 (2011).
    • (2011) Immunol , vol.11 , pp. 389-402
    • West, A.P.1    Shadel, G.S.2    Ghosh, S.3
  • 3
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3
    • Seth, R. B., Sun, L., Ea, C. K., Chen, Z. J. Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3. Cell 122, 669-682 (2005).
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 4
    • 79956314622 scopus 로고    scopus 로고
    • Immune signaling by RIG-I-like receptors
    • Loo, Y. M., Gale, M. Jr. Immune signaling by RIG-I-like receptors. Immunity 34, 680-692 (2011).
    • (2011) Immunity , vol.34 , pp. 680-692
    • Loo, Y.M.1    Gale, M.2
  • 5
    • 77957745555 scopus 로고    scopus 로고
    • Type i interferon: Friend or foe?
    • Trinchieri, G. Type I interferon: friend or foe? J. Exp. Med. 207, 2053-2063 (2010).
    • (2010) J. Exp. Med , vol.207 , pp. 2053-2063
    • Trinchieri, G.1
  • 6
    • 84860523111 scopus 로고    scopus 로고
    • Into the eye of the cytokine storm
    • Tisoncik, J. R. et al. Into the eye of the cytokine storm. Microbiol. Mol. Biol. Rev. 76, 16-32 (2012).
    • (2012) Microbiol. Mol. Biol. Rev , vol.76 , pp. 16-32
    • Tisoncik, J.R.1
  • 7
    • 84925137606 scopus 로고    scopus 로고
    • Mutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome
    • Jang, M. A. et al. Mutations in DDX58, which encodes RIG-I, cause atypical Singleton-Merten syndrome. Am. J. Hum. Genet. 96, 266-274 (2015).
    • (2015) Am. J. Hum. Genet , vol.96 , pp. 266-274
    • Jang, M.A.1
  • 8
    • 84902367750 scopus 로고    scopus 로고
    • Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis
    • Suarez-Calvet, X. et al. Altered RIG-I/DDX58-mediated innate immunity in dermatomyositis. J. Pathol. 233, 258-268 (2014).
    • (2014) J. Pathol , vol.233 , pp. 258-268
    • Suarez-Calvet, X.1
  • 9
    • 84860499060 scopus 로고    scopus 로고
    • Emerging role of ubiquitination in antiviral RIG-I signaling
    • Maelfait, J., Beyaert, R. Emerging role of ubiquitination in antiviral RIG-I signaling. Microbiol. Mol. Biol. Rev. 76, 33-45 (2012).
    • (2012) Microbiol. Mol. Biol. Rev , vol.76 , pp. 33-45
    • Maelfait, J.1    Beyaert, R.2
  • 10
    • 33645217490 scopus 로고    scopus 로고
    • The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase
    • Zou, W., Zhang, D. E. The interferon-inducible ubiquitin-protein isopeptide ligase (E3) EFP also functions as an ISG15 E3 ligase. J. Biol. Chem. 281, 3989-3994 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 3989-3994
    • Zou, W.1    Zhang, D.E.2
  • 11
    • 34247341367 scopus 로고    scopus 로고
    • TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity
    • Gack, M. U. et al. TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity. Nature 446, 916-920 (2007).
    • (2007) Nature , vol.446 , pp. 916-920
    • Gack, M.U.1
  • 12
    • 79953162495 scopus 로고    scopus 로고
    • SUMOylation of RIG-I positively regulates the type i interferon signaling
    • Mi, Z., Fu, J., Xiong, Y., Tang, H. SUMOylation of RIG-I positively regulates the type I interferon signaling. Protein & cell 1, 275-283, doi: 10.1007/s13238-010-0030-1 (2010).
    • (2010) Protein & Cell , vol.1 , pp. 275-283
    • Mi, Z.1    Fu, J.2    Xiong, Y.3    Tang, H.4
  • 13
    • 35348921764 scopus 로고    scopus 로고
    • The Atg5 Atg12 conjugate associates with innate antiviral immune responses
    • Jounai, N. et al. The Atg5 Atg12 conjugate associates with innate antiviral immune responses. Proc. Natl. Acad. Sci. USA. 104, 14050-14055 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 14050-14055
    • Jounai, N.1
  • 14
    • 38349189787 scopus 로고    scopus 로고
    • Negative feedback regulation of RIG-I-mediated antiviral signaling by interferoninduced ISG15 conjugation
    • Kim, M. J., Hwang, S. Y., Imaizumi, T., Yoo, J. Y. Negative feedback regulation of RIG-I-mediated antiviral signaling by interferoninduced ISG15 conjugation. J. Virol. 82, 1474-1483 (2008).
    • (2008) J. Virol , vol.82 , pp. 1474-1483
    • Kim, M.J.1    Hwang, S.Y.2    Imaizumi, T.3    Yoo, J.Y.4
  • 15
  • 16
    • 0033551210 scopus 로고    scopus 로고
    • A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2
    • Liu, Y. C. et al. A MHC-encoded ubiquitin-like protein (FAT10) binds noncovalently to the spindle assembly checkpoint protein MAD2. Proc. Natl. Acad. Sci. USA. 96, 4313-4318 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 4313-4318
    • Liu, Y.C.1
  • 17
    • 81355161184 scopus 로고    scopus 로고
    • FAT10 mediates the effect of TNF-alpha in inducing chromosomal instability
    • Ren, J., Wang, Y., Gao, Y., Mehta, S. B., Lee, C. G. FAT10 mediates the effect of TNF-alpha in inducing chromosomal instability. J. Cell. Sci. 124, 3665-3675 (2011).
    • (2011) J. Cell. Sci , vol.124 , pp. 3665-3675
    • Ren, J.1    Wang, Y.2    Gao, Y.3    Mehta, S.B.4    Lee, C.G.5
  • 18
    • 59349096934 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition
    • Kalveram, B., Schmidtke, G., Groettrup, M. The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition. J. Cell. Sci. 121, 4079-4088 (2008).
    • (2008) J. Cell. Sci , vol.121 , pp. 4079-4088
    • Kalveram, B.1    Schmidtke, G.2    Groettrup, M.3
  • 19
    • 0038192327 scopus 로고    scopus 로고
    • Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
    • Lee, C. G. et al. Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers. Oncogene 22, 2592-2603 (2003).
    • (2003) Oncogene , vol.22 , pp. 2592-2603
    • Lee, C.G.1
  • 20
    • 53649108526 scopus 로고    scopus 로고
    • Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon
    • Lukasiak, S. et al. Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon. Oncogene 27, 6068-6074 (2008).
    • (2008) Oncogene , vol.27 , pp. 6068-6074
    • Lukasiak, S.1
  • 21
    • 84899493959 scopus 로고    scopus 로고
    • NFkappaB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53
    • Choi, Y., Kim, J. K., Yoo, J. Y. NFkappaB and STAT3 synergistically activate the expression of FAT10, a gene counteracting the tumor suppressor p53. Mol. Oncol. 8, 642-655 (2014).
    • (2014) Mol. Oncol , vol.8 , pp. 642-655
    • Choi, Y.1    Kim, J.K.2    Yoo, J.Y.3
  • 22
    • 84894047658 scopus 로고    scopus 로고
    • As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3beta pathway
    • Liu, L. et al. As an independent prognostic factor, FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3beta pathway. Oncogene 33, 909-920 (2014).
    • (2014) Oncogene , vol.33 , pp. 909-920
    • Liu, L.1
  • 23
    • 84907484229 scopus 로고    scopus 로고
    • Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying betacatenin degradation
    • Yuan, R. et al. Ubiquitin-like protein FAT10 promotes the invasion and metastasis of hepatocellular carcinoma by modifying betacatenin degradation. Cancer Res. 74, 5287-5300 (2014).
    • (2014) Cancer Res , vol.74 , pp. 5287-5300
    • Yuan, R.1
  • 24
    • 84865060036 scopus 로고    scopus 로고
    • Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity
    • Onomoto, K. et al. Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PloS one 7, e43031, doi: 10.1371/journal.pone.0043031 (2012).
    • (2012) PloS One , vol.7 , pp. e43031
    • Onomoto, K.1
  • 25
    • 84883271505 scopus 로고    scopus 로고
    • Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses
    • Ng, C. S. et al. Encephalomyocarditis virus disrupts stress granules, the critical platform for triggering antiviral innate immune responses. J. Virol. 87, 9511-9522 (2013).
    • (2013) J. Virol , vol.87 , pp. 9511-9522
    • Ng, C.S.1
  • 26
    • 84872199305 scopus 로고    scopus 로고
    • The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation
    • Aichem, A. et al. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. J. Cell. Sci. 125, 4576-4585 (2012).
    • (2012) J. Cell. Sci , vol.125 , pp. 4576-4585
    • Aichem, A.1
  • 27
    • 84855413453 scopus 로고    scopus 로고
    • FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination
    • Buchsbaum, S., Bercovich, B., Ciechanover, A. FAT10 is a proteasomal degradation signal that is itself regulated by ubiquitination. Mol. Biol. Cell. 23, 225-232 (2012).
    • (2012) Mol. Biol. Cell , vol.23 , pp. 225-232
    • Buchsbaum, S.1    Bercovich, B.2    Ciechanover, A.3
  • 28
    • 55949131282 scopus 로고    scopus 로고
    • Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction
    • Gack, M. U. et al. Roles of RIG-I N-terminal tandem CARD and splice variant in TRIM25-mediated antiviral signal transduction. Proc. Natl. Acad. Sci. USA 105, 16743-16748 (2008).
    • (2008) Proc. Natl. Acad. Sci. USA , vol.105 , pp. 16743-16748
    • Gack, M.U.1
  • 29
    • 84947040229 scopus 로고    scopus 로고
    • TRIM25 has a dual function in the p53/Mdm2 circuit
    • Zhang, P. et al. TRIM25 has a dual function in the p53/Mdm2 circuit. Oncogene, doi: 10.1038/onc.2015.21 (2015).
    • (2015) Oncogene
    • Zhang, P.1
  • 30
    • 79959350721 scopus 로고    scopus 로고
    • NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kappaB signaling pathways
    • Allen, I. C. et al. NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-kappaB signaling pathways. Immunity 34, 854-865 (2011).
    • (2011) Immunity , vol.34 , pp. 854-865
    • Allen, I.C.1
  • 31
    • 84901301160 scopus 로고    scopus 로고
    • HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1
    • Peng, Y., Xu, R., Zheng, X. HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1. PLoS Pathog. 10, e1004041, doi: 10.1371/journal.ppat.1004041 (2014).
    • (2014) PLoS Pathog , vol.10 , pp. e1004041
    • Peng, Y.1    Xu, R.2    Zheng, X.3
  • 32
    • 77951902675 scopus 로고    scopus 로고
    • NLRC5 negatively regulates the NF-kappaB and type i interferon signaling pathways
    • Cui, J. et al. NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways. Cell. 141, 483-496 (2010).
    • (2010) Cell , vol.141 , pp. 483-496
    • Cui, J.1
  • 33
    • 78651401005 scopus 로고    scopus 로고
    • RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I
    • Solis, M. et al. RIG-I-mediated antiviral signaling is inhibited in HIV-1 infection by a protease-mediated sequestration of RIG-I. J. Virol. 85, 1224-1236 (2011).
    • (2011) J. Virol , vol.85 , pp. 1224-1236
    • Solis, M.1
  • 34
    • 84896930327 scopus 로고    scopus 로고
    • Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type i interferon responses
    • Santiago, F. W. et al. Hijacking of RIG-I signaling proteins into virus-induced cytoplasmic structures correlates with the inhibition of type I interferon responses. J. Virol. 88, 4572-4585 (2014).
    • (2014) J. Virol , vol.88 , pp. 4572-4585
    • Santiago, F.W.1
  • 36
    • 70350325586 scopus 로고    scopus 로고
    • FAT10: A novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy
    • Snyder, A. et al. FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. J. Virol. 83, 11983-11988, (2009).
    • (2009) J. Virol , vol.83 , pp. 11983-11988
    • Snyder, A.1
  • 37
    • 84911978547 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice
    • Spinnenhirn, V. et al. The ubiquitin-like modifier FAT10 decorates autophagy-targeted Salmonella and contributes to Salmonella resistance in mice. J. Cell. Sci. 127, 4883-4893 (2014).
    • (2014) J. Cell. Sci , vol.127 , pp. 4883-4893
    • Spinnenhirn, V.1
  • 38
    • 33745456782 scopus 로고    scopus 로고
    • FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences
    • Canaan, A. et al. FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences. Mol. Cell. Biol. 26, 5180-5189 (2006).
    • (2006) Mol. Cell. Biol , vol.26 , pp. 5180-5189
    • Canaan, A.1
  • 39
    • 84945152099 scopus 로고    scopus 로고
    • The ubiquitin-like modifier FAT10 Is selectively expressed in medullary thymic epithelial cells and modifies T Cell Selection
    • Buerger, S. et al. The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J. Immunol. 195, 4106-4116 (2015).
    • (2015) J. Immunol , vol.195 , pp. 4106-4116
    • Buerger, S.1
  • 40
    • 80051951102 scopus 로고    scopus 로고
    • FAT10 protein binds to polyglutamine proteins and modulates their solubility
    • Nagashima, Y., Kowa, H., Tsuji, S., Iwata, A. FAT10 protein binds to polyglutamine proteins and modulates their solubility. J. Biol. Chem. 286, 29594-29600 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 29594-29600
    • Nagashima, Y.1    Kowa, H.2    Tsuji, S.3    Iwata, A.4
  • 41
    • 84868343522 scopus 로고    scopus 로고
    • Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS
    • Buchsbaum, S., Bercovich, B., Ziv, T., Ciechanover, A. Modification of the inflammatory mediator LRRFIP2 by the ubiquitin-like protein FAT10 inhibits its activity during cellular response to LPS. Biochem. Biophys. Res. Commun. 428, 11-16 (2012).
    • (2012) Biochem. Biophys. Res. Commun , vol.428 , pp. 11-16
    • Buchsbaum, S.1    Bercovich, B.2    Ziv, T.3    Ciechanover, A.4
  • 42
    • 65249135027 scopus 로고    scopus 로고
    • Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions
    • Mukherjee, A. et al. Retinoic acid-induced gene-1 (RIG-I) associates with the actin cytoskeleton via caspase activation and recruitment domain-dependent interactions. J. Biol.Chem. 284, 6486-6494 (2009).
    • (2009) J. Biol.Chem , vol.284 , pp. 6486-6494
    • Mukherjee, A.1
  • 43
    • 34248226821 scopus 로고    scopus 로고
    • Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton
    • Legrand-Poels, S. et al. Modulation of Nod2-dependent NF-kappaB signaling by the actin cytoskeleton. J. Cell. Sci. 120, 1299-1310 (2007).
    • (2007) J. Cell. Sci , vol.120 , pp. 1299-1310
    • Legrand-Poels, S.1
  • 44
    • 0035370261 scopus 로고    scopus 로고
    • The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases
    • Goedert, M. The significance of tau and alpha-synuclein inclusions in neurodegenerative diseases. Curr. Opin. Genet. Dev. 11, 343-351 (2001).
    • (2001) Curr. Opin. Genet. Dev , vol.11 , pp. 343-351
    • Goedert, M.1
  • 45
    • 0035869118 scopus 로고    scopus 로고
    • Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells
    • Balajee, A. S., Geard, C. R. Chromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cells. Nucleic Acid. Res. 29, 1341-1351 (2001).
    • (2001) Nucleic Acid. Res , vol.29 , pp. 1341-1351
    • Balajee, A.S.1    Geard, C.R.2
  • 46
    • 47549099397 scopus 로고    scopus 로고
    • Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system
    • Tuoc, T. C., Stoykova, A. Trim11 modulates the function of neurogenic transcription factor Pax6 through ubiquitin-proteosome system. Genes. Dev. 22, 1972-1986 (2008).
    • (2008) Genes. Dev , vol.22 , pp. 1972-1986
    • Tuoc, T.C.1    Stoykova, A.2
  • 47
    • 11144243412 scopus 로고    scopus 로고
    • Modulation of neurodegeneration by molecular chaperones
    • Muchowski, P. J., Wacker, J. L. Modulation of neurodegeneration by molecular chaperones. Nat. Rev. Neurosci 6, 11-22 (2005).
    • (2005) Nat. Rev. Neurosci , vol.6 , pp. 11-22
    • Muchowski, P.J.1    Wacker, J.L.2
  • 48
    • 0037142070 scopus 로고    scopus 로고
    • Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth
    • Urano, T. et al. Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature 417, 871-875 (2002).
    • (2002) Nature , vol.417 , pp. 871-875
    • Urano, T.1
  • 49
    • 58149185720 scopus 로고    scopus 로고
    • Active caspase-1-mediated secretion of retinoic acid inducible gene-I
    • Kim, M. J., Yoo, J. Y. Active caspase-1-mediated secretion of retinoic acid inducible gene-I. J. Immunol. 181, 7324-7331 (2008).
    • (2008) J. Immunol , vol.181 , pp. 7324-7331
    • Kim, M.J.1    Yoo, J.Y.2
  • 50
    • 84859336804 scopus 로고    scopus 로고
    • 5-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity
    • Hwang, S. Y. et al. 5?-Triphosphate-RNA-independent activation of RIG-I via RNA aptamer with enhanced antiviral activity. Nucleic Acids. Res. 40, 2724-2733, doi: 10.1093/nar/gkr1098 (2012).
    • (2012) Nucleic Acids. Res , vol.40 , pp. 2724-2733
    • Hwang, S.Y.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.