Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6

Journal of Biological Chemistry

Volumn 287, Issue 19, 2012, Pages 15512-15522

  Gavin, James M ^a   Chen, Jesse J ^a   Liao, Hua ^a   Rollins, Neil ^a   Yang, Xiaofeng ^a   Xu, Qing ^a   Ma, Jingya ^a   Loke, Huay Keng ^a   Lingaraj, Trupti ^a   Brownell, James E ^a   Mallender, William D ^a   Gould, Alexandra E ^a   Amidon, Benjamin S ^a   Dick, Lawrence R ^a  

^a MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION PROCESS; ADDUCT FORMATION; CATALYTIC MECHANISMS; EXPRESSION LEVELS; KINETIC ANALYSIS; KINETIC BEHAVIOR; MECHANISTIC STUDIES; PRE-STEADY STATE; TERNARY COMPLEX; THIOESTERS; UBIQUITIN; UBIQUITIN-LIKE; UBIQUITIN-LIKE PROTEINS;

CHEMICAL ACTIVATION; ENZYMES;

PROTEINS;

ADENOSINE PHOSPHATE; ADENOSINE TRIPHOSPHATE; FAT10 PROTEIN; LIGASE INHIBITOR; PYROPHOSPHATE; THIOESTER; UBA1 EZYME; UBA6 ENZYME; UBIQUITIN; UBIQUITIN ACTIVATING ENZYME E1 INHIBITOR; UBIQUITIN CONJUGATING ENZYME E2; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BIOCHEMISTRY; BIOPHYSICS; CATALYSIS; COMPLEX FORMATION; CONTROLLED STUDY; COVALENT BOND; DNA ADDUCT; ENZYME MECHANISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ACTIVATION; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN MODIFICATION; PROTEIN TRANSPORT; STEADY STATE;

ADENOSINE MONOPHOSPHATE; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, WESTERN; CELL LINE; DIPHOSPHATES; ENZYME ACTIVATION; HUMANS; INTERFERON-GAMMA; KINETICS; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; PROTEIN BINDING; SPODOPTERA; SUBSTRATE SPECIFICITY; SULFHYDRYL COMPOUNDS; SURFACE PLASMON RESONANCE; TUMOR NECROSIS FACTOR-ALPHA; UBIQUITIN-ACTIVATING ENZYMES; UBIQUITINS;

EID: 84860852562     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.336198     Document Type: Article

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