메뉴 건너뛰기




Volumn 10, Issue 2-3, 2010, Pages 186-193

Pancreatic stellate cells increase the invasion of human pancreatic cancer cells through the stromal cell-derived factor-1/CXCR4 Axis

Author keywords

Pancreatic cancer progression; Pancreatic stellate cells; Supernatants

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; PLERIXAFOR; STROMAL CELL DERIVED FACTOR 1; STROMAL CELL DERIVED FACTOR 1ALPHA; CULTURE MEDIUM; CXCL12 PROTEIN, HUMAN;

EID: 77952304593     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000236012     Document Type: Article
Times cited : (103)

References (44)
  • 2
    • 0036883940 scopus 로고    scopus 로고
    • Pancreatic cancer biology and genetics
    • Bardeesy N, DePinho RA: Pancreatic cancer biology and genetics. Nat Rev Cancer 2002; 2: 897-909.
    • (2002) Nat Rev Cancer , vol.2 , pp. 897-909
    • Bardeesy, N.1    Depinho, R.A.2
  • 3
    • 0031918822 scopus 로고    scopus 로고
    • Problems in the diagnosis and treatment of a so-called mucin-producing tumor of the pancreas
    • Kimura W, Kuroda A, Makuuchi M: Problems in the diagnosis and treatment of a socalled mucin-producing tumor of the pancreas. Pancreas 1998; 16: 363-369. (Pubitemid 28158042)
    • (1998) Pancreas , vol.16 , Issue.3 , pp. 363-369
    • Kimura, W.1    Kuroda, A.2    Makuuchi, M.3
  • 6
    • 2342640981 scopus 로고    scopus 로고
    • Radiation to Stromal Fibroblasts Increases Invasiveness of Pancreatic Cancer Cells through Tumor-Stromal Interactions
    • DOI 10.1158/0008-5472.CAN-03-2464
    • Ohuchida K, Mizumoto K, Murakami M, Qian LW, Sato N, Nagai E, Matsumoto K, Nakamura T, Tanaka M: Radiation to stromal fibroblasts increases invasiveness of pancreatic cancer cells through tumor-stromal interactions. Cancer Res 2004; 64: 3215-3222. (Pubitemid 38581425)
    • (2004) Cancer Research , vol.64 , Issue.9 , pp. 3215-3222
    • Ohuchida, K.1    Mizumoto, K.2    Murakami, M.3    Qian, L.-W.4    Sato, N.5    Nagai, E.6    Matsumoto, K.7    Nakamura, T.8    Tanaka, M.9
  • 7
    • 0346157370 scopus 로고    scopus 로고
    • Tumor-stroma interaction of human pancreatic cancer: Acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins
    • Miyamoto H, Murakami T, Tsuchida K, Sugino H, Miyake H, Tashiro S: Tumor-stroma interaction of human pancreatic cancer: acquired resistance to anticancer drugs and proliferation regulation is dependent on extracellular matrix proteins. Pancreas 2004; 28: 38-44.
    • (2004) Pancreas , vol.28 , pp. 38-44
    • Miyamoto, H.1    Murakami, T.2    Tsuchida, K.3    Sugino, H.4    Miyake, H.5    Tashiro, S.6
  • 8
    • 10744221950 scopus 로고    scopus 로고
    • Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta
    • Müerköster S, Wegehenkel K, Arlt A, Witt M, Sipos B, Kruse ML, Sebens T, Klöppel G, Kalthoff H, Fölsch UR, Schäfer H: Tumor stroma interactions induce chemoresistance in pancreatic ductal carcinoma cells involving increased secretion and paracrine effects of nitric oxide and interleukin-1beta. Cancer Res 2004; 64: 1331-1337.
    • (2004) Cancer Res , vol.64 , pp. 1331-1337
    • Müerköster, S.1    Wegehenkel, K.2    Arlt, A.3    Witt, M.4    Sipos, B.5    Kruse, M.L.6    Sebens, T.7    Klöppel, G.8    Kalthoff, H.9    Fölsch, U.R.10    Schäfer, H.11
  • 14
    • 45249091881 scopus 로고    scopus 로고
    • Regulation of HGF and SDF-1 expression by oral fibroblasts - Implications for invasion of oral cancer
    • Daly AJ, McIlreavey L, Irwin CR: Regulation of HGF and SDF-1 expression by oral fibroblasts - implications for invasion of oral cancer. Oral Oncol 2008; 44: 646-651.
    • (2008) Oral Oncol , vol.44 , pp. 646-651
    • Daly, A.J.1    McIlreavey, L.2    Irwin, C.R.3
  • 15
    • 0042941495 scopus 로고    scopus 로고
    • Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors
    • Wu X, Jin C, Wang F, Yu C, McKeehan WL: Stromal cell heterogeneity in fibroblast growth factor-mediated stromal-epithelial cell cross-talk in premalignant prostate tumors. Cancer Res 2003; 63: 4936-4944.
    • (2003) Cancer Res , vol.63 , pp. 4936-4944
    • Wu, X.1    Jin, C.2    Wang, F.3    Yu, C.4    McKeehan, W.L.5
  • 17
    • 33646261865 scopus 로고    scopus 로고
    • Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells
    • Holland JD, Kochetkova M, Akekawatchai C, Dottore M, Lopez A, McColl SR: Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. Cancer Res 2006; 66: 4117-4124.
    • (2006) Cancer Res , vol.66 , pp. 4117-4124
    • Holland, J.D.1    Kochetkova, M.2    Akekawatchai, C.3    Dottore, M.4    Lopez, A.5    McColl, S.R.6
  • 19
    • 22244470409 scopus 로고    scopus 로고
    • Stromal cell-derived factor- 1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: Von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor
    • Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL: Stromal cell-derived factor- 1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor. Cancer Res 2005; 65: 6178-6188.
    • (2005) Cancer Res , vol.65 , pp. 6178-6188
    • Zagzag, D.1    Krishnamachary, B.2    Yee, H.3    Okuyama, H.4    Chiriboga, L.5    Ma, A.6    Melamed, J.7    Semenza, G.L.8
  • 20
    • 0042941765 scopus 로고    scopus 로고
    • Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro
    • Chen Y, Stamatoyannopoulos G, Song CZ: Down-regulation of CXCR4 by inducible small interfering RNA inhibits breast cancer cell invasion in vitro. Cancer Res 2003; 63: 4801-4804.
    • (2003) Cancer Res , vol.63 , pp. 4801-4804
    • Chen, Y.1    Stamatoyannopoulos, G.2    Song, C.Z.3
  • 21
    • 0345687920 scopus 로고    scopus 로고
    • Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells
    • Burger M, Glodek A, Hartmann T, Schmitt- Gräff A, Silberstein LE, Fujii N, Kipps TJ, Burger JA: Functional expression of CXCR4 (CD184) on small-cell lung cancer cells mediates migration, integrin activation, and adhesion to stromal cells. Oncogene 2003; 22: 8093-8101.
    • (2003) Oncogene , vol.22 , pp. 8093-8101
    • Burger, M.1    Glodek, A.2    Hartmann, T.3    Schmitt-Gräff, A.4    Silberstein, L.E.5    Fujii, N.6    Kipps, T.J.7    Burger, J.A.8
  • 22
    • 10044284415 scopus 로고    scopus 로고
    • CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion
    • DOI 10.1038/labinvest.3700181
    • Singh S, Singh UP, Grizzle WE, Lillard JW Jr: CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion. Lab Invest 2004; 84: 1666-1676. (Pubitemid 39600573)
    • (2004) Laboratory Investigation , vol.84 , Issue.12 , pp. 1666-1676
    • Singh, S.1    Singh, U.P.2    Grizzle, W.E.3    Lillard Jr., J.W.4
  • 25
    • 8544223594 scopus 로고    scopus 로고
    • Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4
    • Marchesi F, Monti P, Leone BE, Zerbi A, Vecchi A, Piemonti L, Mantovani A, Allavena P: Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4. Cancer Res 2004; 64: 8420-8427.
    • (2004) Cancer Res , vol.64 , pp. 8420-8427
    • Marchesi, F.1    Monti, P.2    Leone, B.E.3    Zerbi, A.4    Vecchi, A.5    Piemonti, L.6    Mantovani, A.7    Allavena, P.8
  • 30
    • 0035902141 scopus 로고    scopus 로고
    • The microenvironment of the tumour-host interface
    • Liotta LA, Kohn EC: The microenvironment of the tumour-host interface. Nature 2001; 411: 375-379.
    • (2001) Nature , vol.411 , pp. 375-379
    • Liotta, L.A.1    Kohn, E.C.2
  • 32
    • 0037899253 scopus 로고    scopus 로고
    • Role of tissue stroma in cancer cell invasion
    • De Wever O, Mareel M: Role of tissue stroma in cancer cell invasion. J Pathol 2003; 200: 429-447.
    • (2003) J Pathol , vol.200 , pp. 429-447
    • De Wever, O.1    Mareel, M.2
  • 33
    • 44849119750 scopus 로고    scopus 로고
    • Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3
    • Jiang HB, Xu M, Wang XP: Pancreatic stellate cells promote proliferation and invasiveness of human pancreatic cancer cells via galectin-3. World J Gastroenterol 2008; 14: 2023-2028.
    • (2008) World J Gastroenterol , vol.14 , pp. 2023-2028
    • Jiang, H.B.1    Xu, M.2    Wang, X.P.3
  • 35
  • 36
    • 33644789290 scopus 로고    scopus 로고
    • Stromal cell derived factor-1: Its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer
    • Kang H, Watkins G, Parr C, Douglas-Jones A, Mansel RE, Jiang WG: Stromal cell derived factor-1: its influence on invasiveness and migration of breast cancer cells in vitro, and its association with prognosis and survival in human breast cancer. Breast Cancer Res 2005; 7:R402-R410.
    • (2005) Breast Cancer Res , vol.7
    • Kang, H.1    Watkins, G.2    Parr, C.3    Douglas-Jones, A.4    Mansel, R.E.5    Jiang, W.G.6
  • 37
    • 33845348208 scopus 로고    scopus 로고
    • P53 attenuates cancer cell migration and invasion through repression of SDF- 1/CXCL12 expression in stromal fibroblasts
    • Moskovits N, Kalinkovich A, Bar J, Lapidot T, Oren M: P53 attenuates cancer cell migration and invasion through repression of SDF- 1/CXCL12 expression in stromal fibroblasts. Cancer Res 2006; 66: 10671-10676.
    • (2006) Cancer Res , vol.66 , pp. 10671-10676
    • Moskovits, N.1    Kalinkovich, A.2    Bar, J.3    Lapidot, T.4    Oren, M.5
  • 38
    • 33645458005 scopus 로고    scopus 로고
    • Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factoralpha and stromal-derived factor-1 released in stroma
    • Ohira S, Sasaki M, Harada K, Sato Y, Zen Y, Isse K, Kozaka K, Ishikawa A, Oda K, Nimura Y, Nakanuma Y: Possible regulation of migration of intrahepatic cholangiocarcinoma cells by interaction of CXCR4 expressed in carcinoma cells with tumor necrosis factoralpha and stromal-derived factor-1 released in stroma. Am J Pathol 2006; 168: 1155-1168.
    • (2006) Am J Pathol , vol.168 , pp. 1155-1168
    • Ohira, S.1    Sasaki, M.2    Harada, K.3    Sato, Y.4    Zen, Y.5    Isse, K.6    Kozaka, K.7    Ishikawa, A.8    Oda, K.9    Nimura, Y.10    Nakanuma, Y.11
  • 39
    • 45249091881 scopus 로고    scopus 로고
    • Regulation of HGF and SDF-1 expression by oral fibroblasts - Implications for invasion of oral cancer
    • Daly AJ, McIlreavey L, Irwin CR: Regulation of HGF and SDF-1 expression by oral fibroblasts - implications for invasion of oral cancer. Oral Oncol 2008; 44: 646-651.
    • (2008) Oral Oncol , vol.44 , pp. 646-651
    • Daly, A.J.1    McIlreavey, L.2    Irwin, C.R.3
  • 40
    • 33344464945 scopus 로고    scopus 로고
    • CXCR4: A key receptor in the crosstalk between tumor cells and their microenvironment
    • Burger JA, Kipps TJ: CXCR4: a key receptor in the crosstalk between tumor cells and their microenvironment. Blood 2006; 107: 1761-1767.
    • (2006) Blood , vol.107 , pp. 1761-1767
    • Burger, J.A.1    Kipps, T.J.2
  • 41
    • 33746868899 scopus 로고    scopus 로고
    • Functions of CXCL12 and CXCR4 in breast cancer
    • Luker KE, Luker GD: Functions of CXCL12 and CXCR4 in breast cancer. Cancer Lett 2006; 238: 30-41.
    • (2006) Cancer Lett , vol.238 , pp. 30-41
    • Luker, K.E.1    Luker, G.D.2
  • 43
    • 3042822267 scopus 로고    scopus 로고
    • Cancer and the chemokine network
    • Balkwill F: Cancer and the chemokine network. Nat Rev Cancer 2004; 4: 540-550.
    • (2004) Nat Rev Cancer , vol.4 , pp. 540-550
    • Balkwill, F.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.