Extended lifespan and reduced adiposity in mice lacking the FAT10 gene

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 14, 2014, Pages 5313-5318

  Canaan, Allon ^a   DeFuria, Jason ^b   Perelman, Eddie ^c   Schultz, Vincent ^a   Seay, Montrell ^a   Tuck, David ^a   Flavell, Richard A ^a   Snyder, Michael P ^d   Obin, Martin S ^b   Weissman, Sherman M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TUFTS UNIVERSITY   (United States)

^c BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^d STANFORD UNIVERSITY   (United States)

Author keywords

Longevity; Mammals; Obesity

Indexed keywords

FUEL; GLUCOSE; INSULIN; INTERLEUKIN 10;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHRONIC DISEASE; CONTROLLED STUDY; F ADJACENT TRANSCRIPT 10 GENE; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; IMMUNOREGULATION; INFLAMMATION; INSULIN BLOOD LEVEL; INSULIN SENSITIVITY; KNOCKOUT MOUSE; LIFE EXTENSION; LIFESPAN; MALE; METABOLIC RATE; METABOLIC REGULATION; MOUSE; NONHUMAN; OBESITY; OBSERVATIONAL STUDY; PHENOTYPE; PLEIOTROPY; PRIORITY JOURNAL; SKELETAL MUSCLE;

LONGEVITY; MAMMALS; OBESITY;

ADIPOCYTES; ADIPOSITY; ANIMALS; BIOLOGICAL MARKERS; ENERGY METABOLISM; FEMALE; LONGEVITY; MALE; MICE; MICE, KNOCKOUT; OXIDATION-REDUCTION; TRIGLYCERIDES; UBIQUITINS;

EID: 84898032485     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1323426111     Document Type: Article

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