Knockout of inositol-requiring enzyme 1α in pro-opiomelanocortin neurons decreases fat mass via increasing energy expenditure

Open Biology

Volumn 6, Issue 8, 2016, Pages

  Xiao, Yuzhong ^a   Xia, Tingting ^a   Yu, Junjie ^a   Deng, Yalan ^a   Liu, Hao ^a   Liu, Bin ^a   Chen, Shanghai ^a   Liu, Yong ^a   Guo, Feifan ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

Author keywords

Hypothalamus; Inositol requiring enzyme 1 ; Leptin sensitivity; Obesity; Pro opiomelanocortin neurons

Indexed keywords

ALPHA INTERMEDIN; ERN1 PROTEIN, MOUSE; PROOPIOMELANOCORTIN; PROTEIN SERINE THREONINE KINASE; RIBONUCLEASE;

ANIMAL; CHEMICALLY INDUCED; ENERGY METABOLISM; GENE INACTIVATION; GENETICS; HYPOTHALAMUS; LIPID DIET; METABOLISM; MOUSE; NERVE CELL; OBESITY; THERMOGENESIS; UNDERWEIGHT;

ALPHA-MSH; ANIMALS; DIET, HIGH-FAT; ENDORIBONUCLEASES; ENERGY METABOLISM; GENE KNOCKOUT TECHNIQUES; HYPOTHALAMUS; MICE; NEURONS; OBESITY; PRO-OPIOMELANOCORTIN; PROTEIN-SERINE-THREONINE KINASES; THERMOGENESIS; THINNESS;

EID: 84990829191     PISSN: None     EISSN: 20462441     Source Type: Journal    
DOI: 10.1098/rsob.160131     Document Type: Article

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