Foxp3 and Toll-like receptor signaling balance T reg cell anabolic metabolism for suppression

Nature Immunology

Volumn 17, Issue 12, 2016, Pages 1459-1466

  Gerriets, Valerie A ^a   Kishton, Rigel J ^a   Johnson, Marc O ^a,b   Cohen, Sivan ^a   Siska, Peter J ^b   Nichols, Amanda G ^a   Warmoes, Marc O ^c   De Cubas, Aguirre A ^d   MacIver, Nancie J ^e   Locasale, Jason W ^a   Turka, Laurence A ^f   Wells, Andrew D ^g   Rathmell, Jeffrey C ^a,b  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VANDERBILT UNIVERSITY   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

^d VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^e DUKE UNIVERSITY   (United States)

^f MASSACHUSETTS GENERAL HOSPITAL   (United States)

^g CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; GLUCOSE TRANSPORTER 1; KI 67 ANTIGEN; LACTIC ACID; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; SLC2A1 PROTEIN, MOUSE; TARGET OF RAPAMYCIN KINASE; TOLL LIKE RECEPTOR;

AEROBIC GLYCOLYSIS; AEROBIC METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CATABOLISM; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL GROWTH; CELL METABOLISM; COLITIS; CONTROLLED STUDY; GENE EXPRESSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; IN VIVO STUDY; INTRACELLULAR SIGNALING; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY T LYMPHOCYTE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; GENETICS; GLYCOLYSIS; HELPER CELL; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; METABOLISM; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; FORKHEAD TRANSCRIPTION FACTORS; GLUCOSE TRANSPORTER TYPE 1; GLYCOLYSIS; IMMUNE TOLERANCE; METABOLISM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MULTIPROTEIN COMPLEXES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TOLL-LIKE RECEPTORS; TOR SERINE-THREONINE KINASES;

EID: 84989966066     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3577     Document Type: Article

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