Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses

Nature Immunology

Volumn 16, Issue 2, 2015, Pages 178-187

  Shrestha, Sharad ^a,b   Yang, Kai ^a   Guy, Cliff ^a   Vogel, Peter ^a   Neale, Geoffrey ^a   Chi, Hongbo ^a,b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 2; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; FORKHEAD TRANSCRIPTION FACTOR; FOXP1 PROTEIN, MOUSE; PTEN PROTEIN, HUMAN; REPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; FOLLICULAR HELPER T CELL; GERMINAL CENTER; GLYCOLYSIS; HAPLOINSUFFICIENCY; HELPER CELL; HELPER T CELL TYPE 1; HOMEOSTASIS; HUMAN; HUMAN CELL; IMMUNE SYSTEM; INFLAMMATORY DISEASE; METABOLIC BALANCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; ANIMAL; ENZYMOLOGY; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; TH1 CELL;

ANIMALS; B-LYMPHOCYTES; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; LYMPHOCYTE ACTIVATION; MICE; PTEN PHOSPHOHYDROLASE; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, HELPER-INDUCER; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 84922930171     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3076     Document Type: Article

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