Targeting of TLRs inhibits CD4+ regulatory T cell function and activates lymphocytes in human peripheral blood mononuclear cells

Journal of Immunology

Volumn 193, Issue 2, 2014, Pages 627-634

  Voo, Kui Shin ^a   Bover, Laura ^a   Harline, Megan Lundell ^a   Weng, Jinsheng ^a   Sugimoto, Naoshi ^b   Liu, Yong Jun ^b  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^b MEDIMMUNE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CL 075; CL 097; CPG A; CPG B; CPG C; FLAGELLIN; INTERLEUKIN 10; LIGAND; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; PAM3CSK4; PEPTIDOGLYCAN; POLYINOSINIC POLYCYTIDYLIC ACID; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG;

ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CONTROLLED STUDY; HUMAN; HUMAN CELL; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN TARGETING; REGULATORY T LYMPHOCYTE;

ADULT; ANALYSIS OF VARIANCE; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; FLAGELLIN; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; IMIDAZOLES; INTERFERON-GAMMA; INTERLEUKIN-10; INTERLEUKIN-6; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; LIPOPEPTIDES; LIPOPOLYSACCHARIDES; LYMPHOCYTE ACTIVATION; QUINOLINES; T-LYMPHOCYTES, REGULATORY; THIAZOLES; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84904266667     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1203334     Document Type: Article

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