-
1
-
-
67650752137
-
T cell activation. Annu
-
Smith-Garvin, J. E., Koretzky, G. A., Jordan, M. S. (2009) T cell activation. Annu. Rev. Immunol. 27, 591–619.
-
(2009)
Rev. Immunol
, vol.27
, pp. 591-619
-
-
Smith-Garvin, J.E.1
Koretzky, G.A.2
Jordan, M.S.3
-
2
-
-
27744519400
-
Fuel feeds function: Energy metabolism and the T-cell response
-
Fox, C. J., Hammerman, P. S., Thompson, C. B. (2005) Fuel feeds function: energy metabolism and the T-cell response. Nat. Rev. Immunol. 5, 844–852.
-
(2005)
Nat. Rev. Immunol
, vol.5
, pp. 844-852
-
-
Fox, C.J.1
Hammerman, P.S.2
Thompson, C.B.3
-
3
-
-
33847397525
-
Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells
-
Crellin, N. K., Garcia, R. V., Levings, M. K. (2007) Altered activation of AKT is required for the suppressive function of human CD4+CD25+ T regulatory cells. Blood 109, 2014–2022.
-
(2007)
Blood
, vol.109
, pp. 2014-2022
-
-
Crellin, N.K.1
Garcia, R.V.2
Levings, M.K.3
-
4
-
-
34347237623
-
Flow cytometry-based methods for studying signaling in human CD4+CD25+FOXP3+ T regulatory cells
-
Crellin, N. K., Garcia, R. V., Levings, M. K. (2007) Flow cytometry-based methods for studying signaling in human CD4+CD25+FOXP3+ T regulatory cells. J. Immunol. Methods 324, 92–104.
-
(2007)
J. Immunol. Methods
, vol.324
, pp. 92-104
-
-
Crellin, N.K.1
Garcia, R.V.2
Levings, M.K.3
-
5
-
-
79956221450
-
Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells
-
Patterson, S. J., Han, J. M., Garcia, R., Assi, K., Gao, T., O’Neill, A., Newton, A. C., Levings, M. K. (2011) Cutting edge: PHLPP regulates the development, function, and molecular signaling pathways of regulatory T cells. J. Immunol. 186, 5533–5537.
-
(2011)
J. Immunol
, vol.186
, pp. 5533-5537
-
-
Patterson, S.J.1
Han, J.M.2
Garcia, R.3
Assi, K.4
Gao, T.5
O’Neill, A.6
Newton, A.C.7
Levings, M.K.8
-
6
-
-
45549098562
-
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR
-
Sauer, S., Bruno, L., Hertweck, A., Finlay, D., Leleu, M., Spivakov, M., Knight, Z. A., Cobb, B. S., Cantrell, D., O’Connor, E., Shokat, K. M., Fisher, A. G., Merkenschlager, M. (2008) T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR. Proc. Natl. Acad. Sci. USA 105, 7797–7802.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7797-7802
-
-
Sauer, S.1
Bruno, L.2
Hertweck, A.3
Finlay, D.4
Leleu, M.5
Spivakov, M.6
Knight, Z.A.7
Cobb, B.S.8
Cantrell, D.9
O’Connor, E.10
Shokat, K.M.11
Fisher, A.G.12
Merkenschlager, M.13
-
7
-
-
11144357191
-
Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells
-
Bensinger, S. J., Walsh, P. T., Zhang, J., Carroll, M., Parsons, R., Rathmell, J. C., Thompson, C. B., Burchill, M. A., Farrar, M. A., Turka, L. A. (2004) Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells. J. Immunol. 172, 5287–5296.
-
(2004)
J. Immunol
, vol.172
, pp. 5287-5296
-
-
Bensinger, S.J.1
Walsh, P.T.2
Zhang, J.3
Carroll, M.4
Parsons, R.5
Rathmell, J.C.6
Thompson, C.B.7
Burchill, M.A.8
Farrar, M.A.9
Turka, L.A.10
-
8
-
-
33748335576
-
PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs
-
Walsh, P. T., Buckler, J. L., Zhang, J., Gelman, A. E., Dalton, N. M., Taylor, D. K., Bensinger, S. J., Hancock, W. W., Turka, L. A. (2006) PTEN inhibits IL-2 receptor-mediated expansion of CD4+ CD25+ Tregs. J. Clin. Invest. 116, 2521–2531.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 2521-2531
-
-
Walsh, P.T.1
Buckler, J.L.2
Zhang, J.3
Gelman, A.E.4
Dalton, N.M.5
Taylor, D.K.6
Bensinger, S.J.7
Hancock, W.W.8
Turka, L.A.9
-
9
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth, K. A., Riley, J. L., Harris, M. H., Parry, R. V., Rathmell, J. C., Plas, D. R., Elstrom, R. L., June, C. H., Thompson, C. B. (2002) The CD28 signaling pathway regulates glucose metabolism. Immunity 16, 769–777.
-
(2002)
Immunity
, vol.16
, pp. 769-777
-
-
Frauwirth, K.A.1
Riley, J.L.2
Harris, M.H.3
Parry, R.V.4
Rathmell, J.C.5
Plas, D.R.6
Elstrom, R.L.7
June, C.H.8
Thompson, C.B.9
-
10
-
-
44449165597
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
-
Jacobs, S. R., Herman, C. E., Maciver, N. J., Wofford, J. A., Wieman, H. L., Hammen, J. J., Rathmell, J. C. (2008) Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. J. Immunol. 180, 4476–4486.
-
(2008)
J. Immunol
, vol.180
, pp. 4476-4486
-
-
Jacobs, S.R.1
Herman, C.E.2
Maciver, N.J.3
Wofford, J.A.4
Wieman, H.L.5
Hammen, J.J.6
Rathmell, J.C.7
-
11
-
-
79953172571
-
Cutting edge: Distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek, R. D., Gerriets, V. A., Jacobs, S. R., Macintyre, A. N., MacIver, N. J., Mason, E. F., Sullivan, S. A., Nichols, A. G., Rathmell, J. C. (2011) Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J. Immunol. 186, 3299–3303.
-
(2011)
J. Immunol
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
Maciver, N.J.5
Mason, E.F.6
Sullivan, S.A.7
Nichols, A.G.8
Rathmell, J.C.9
-
12
-
-
84904057246
-
The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function
-
Macintyre, A. N., Gerriets, V. A., Nichols, A. G., Michalek, R. D., Rudolph, M. C., Deoliveira, D., Anderson, S. M., Abel, E. D., Chen, B. J., Hale, L. P., Rathmell, J. C. (2014) The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function. Cell Metab. 20, 61–72.
-
(2014)
Cell Metab
, vol.20
, pp. 61-72
-
-
Macintyre, A.N.1
Gerriets, V.A.2
Nichols, A.G.3
Michalek, R.D.4
Rudolph, M.C.5
Deoliveira, D.6
Erson, S.M.7
Abel, E.D.8
Chen, B.J.9
Hale, L.P.10
Rathmell, J.C.11
-
13
-
-
84897941063
-
TTregs, pTregs, and iTregs: Similarities and differences
-
Shevach, E. M., Thornton, A. M. (2014) tTregs, pTregs, and iTregs: similarities and differences. Immunol. Rev. 259, 88–102.
-
(2014)
Immunol. Rev
, vol.259
, pp. 88-102
-
-
Shevach, E.M.1
Thornton, A.M.2
-
14
-
-
84862998910
-
Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death
-
Jo, H., Mondal, S., Tan, D., Nagata, E., Takizawa, S., Sharma, A. K., Hou, Q., Shanmugasundaram, K., Prasad, A., Tung, J. K., Tejeda, A. O., Man, H., Rigby, A. C., Luo, H. R. (2012) Small molecule-induced cytosolic activation of protein kinase Akt rescues ischemia-elicited neuronal death. Proc. Natl. Acad. Sci. USA 109, 10581–10586.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 10581-10586
-
-
Jo, H.1
Mondal, S.2
Tan, D.3
Nagata, E.4
Takizawa, S.5
Sharma, A.K.6
Hou, Q.7
Shanmugasundaram, K.8
Prasad, A.9
Tung, J.K.10
Tejeda, A.O.11
Man, H.12
Rigby, A.C.13
Luo, H.R.14
-
15
-
-
69449085219
-
GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells
-
Tran, D. Q., Andersson, J., Wang, R., Ramsey, H., Unutmaz, D., Shevach, E. M. (2009) GARP (LRRC32) is essential for the surface expression of latent TGF-beta on platelets and activated FOXP3+ regulatory T cells. Proc. Natl. Acad. Sci. USA 106, 13445–13450.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 13445-13450
-
-
Tran, D.Q.1
Ersson, J.2
Wang, R.3
Ramsey, H.4
Unutmaz, D.5
Shevach, E.M.6
-
16
-
-
44449100271
-
Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin
-
Basu, S., Golovina, T., Mikheeva, T., June, C. H., Riley, J. L. (2008) Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. J. Immunol. 180, 5794–5798.
-
(2008)
J. Immunol
, vol.180
, pp. 5794-5798
-
-
Basu, S.1
Golovina, T.2
Mikheeva, T.3
June, C.H.4
Riley, J.L.5
-
17
-
-
33646856912
-
B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs
-
Chemnitz, J. M., Lanfranco, A. R., Braunstein, I., Riley, J. L. (2006) B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs. J. Immunol. 176, 6603–6614.
-
(2006)
J. Immunol
, vol.176
, pp. 6603-6614
-
-
Chemnitz, J.M.1
Lanfranco, A.R.2
Braunstein, I.3
Riley, J.L.4
-
18
-
-
84881068658
-
The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
-
Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly Y M., Glickman, J. N., Garrett, W. S. (2013) The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science 341, 569–573.
-
(2013)
Science
, vol.341
, pp. 569-573
-
-
Smith, P.M.1
Howitt, M.R.2
Panikov, N.3
Michaud, M.4
Gallini, C.A.5
Bohlooly, Y.M.6
Glickman, J.N.7
Garrett, W.S.8
-
19
-
-
33748460087
-
Foxp3-dependent and-independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis
-
Sugimoto, N., Oida, T., Hirota, K., Nakamura, K., Nomura, T., Uchiyama, T., Sakaguchi, S. (2006) Foxp3-dependent and-independent molecules specific for CD25+CD4+ natural regulatory T cells revealed by DNA microarray analysis. Int. Immunol. 18, 1197–1209.
-
(2006)
Int. Immunol
, vol.18
, pp. 1197-1209
-
-
Sugimoto, N.1
Oida, T.2
Hirota, K.3
Nakamura, K.4
Nomura, T.5
Uchiyama, T.6
Sakaguchi, S.7
-
20
-
-
33847220736
-
Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells
-
Zheng, Y., Josefowicz, S. Z., Kas, A., Chu, T. T., Gavin, M. A., Rudensky, A. Y. (2007) Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells. Nature 445, 936–940.
-
(2007)
Nature
, vol.445
, pp. 936-940
-
-
Zheng, Y.1
Josefowicz, S.Z.2
Kas, A.3
Chu, T.T.4
Gavin, M.A.5
Rudensky, A.Y.6
-
21
-
-
33646168597
-
FOXP3: Of mice and men
-
Ziegler, S. F. (2006) FOXP3: of mice and men. Annu. Rev. Immunol. 24, 209–226.
-
(2006)
Annu. Rev. Immunol
, vol.24
, pp. 209-226
-
-
Ziegler, S.F.1
-
22
-
-
77953747963
-
The PD-1 pathway in tolerance and autoimmunity
-
Francisco, L. M., Sage, P. T., Sharpe, A. H. (2010) The PD-1 pathway in tolerance and autoimmunity. Immunol. Rev. 236, 219–242.
-
(2010)
Immunol. Rev
, vol.236
, pp. 219-242
-
-
Francisco, L.M.1
Sage, P.T.2
Sharpe, A.H.3
-
23
-
-
77955486658
-
Genome-wide identification of human FOXP3 target genes in natural regulatory T cells
-
Sadlon, T. J., Wilkinson, B. G., Pederson, S., Brown, C. Y., Bresatz, S., Gargett, T., Melville, E. L., Peng, K., D’Andrea, R. J., Glonek, G. G., Goodall, G. J., Zola, H., Shannon, M. F., Barry, S. C. (2010) Genome-wide identification of human FOXP3 target genes in natural regulatory T cells. J. Immunol. 185, 1071–1081.
-
(2010)
J. Immunol
, vol.185
, pp. 1071-1081
-
-
Sadlon, T.J.1
Wilkinson, B.G.2
Pederson, S.3
Brown, C.Y.4
Bresatz, S.5
Gargett, T.6
Melville, E.L.7
Peng, K.8
D’Andrea, R.J.9
Glonek, G.G.10
Goodall, G.J.11
Zola, H.12
Shannon, M.F.13
Barry, S.C.14
|