-
1
-
-
6344227760
-
Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand
-
Bauer DE, Harris MH, Plas DR, Lum JJ, Hammerman PS, Rathmell JC, Riley JL, Thompson CB. Cytokine stimulation of aerobic glycolysis in hematopoietic cells exceeds proliferative demand. FASEB J 18: 1303-1305, 2004.
-
(2004)
FASEB J
, vol.18
, pp. 1303-1305
-
-
Bauer, D.E.1
Harris, M.H.2
Plas, D.R.3
Lum, J.J.4
Hammerman, P.S.5
Rathmell, J.C.6
Riley, J.L.7
Thompson, C.B.8
-
2
-
-
33745918951
-
TIGAR, a p53-inducible regulator of glycolysis and apoptosis
-
Bensaad K, Tsuruta A, Selak MA, Vidal MN, Nakano K, Bartrons R, Gottlieb E, Vousden KH. TIGAR, a p53-inducible regulator of glycolysis and apoptosis. Cell 126: 107-120, 2006.
-
(2006)
Cell
, vol.126
, pp. 107-120
-
-
Bensaad, K.1
Tsuruta, A.2
Selak, M.A.3
Vidal, M.N.4
Nakano, K.5
Bartrons, R.6
Gottlieb, E.7
Vousden, K.H.8
-
3
-
-
75649122284
-
Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice
-
Bian L, Josefsson E, Jonsson IM, Verdrengh M, Ohlsson C, Bokarewa M, Tarkowski A, Magnusson M. Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice. Arthritis Res Ther 11: R132, 2009.
-
(2009)
Arthritis Res Ther
, vol.11
-
-
Bian, L.1
Josefsson, E.2
Jonsson, I.M.3
Verdrengh, M.4
Ohlsson, C.5
Bokarewa, M.6
Tarkowski, A.7
Magnusson, M.8
-
4
-
-
33846002728
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth
-
+ channel axis is suppressed in cancer and its normalization promotes apoptosis and inhibits cancer growth. Cancer Cell 11: 37-51, 2007.
-
(2007)
Cancer Cell
, vol.11
, pp. 37-51
-
-
Bonnet, S.1
Archer, S.L.2
Allalunis-Turner, J.3
Haromy, A.4
Beaulieu, C.5
Thompson, R.6
Lee, C.T.7
Lopaschuk, G.D.8
Puttagunta, L.9
Bonnet, S.10
Harry, G.11
Hashimoto, K.12
Porter, C.J.13
Andrade, M.A.14
Thebaud, B.15
Michelakis, E.D.16
-
5
-
-
17044422629
-
Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells
-
Cham CM, Gajewski TF. Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells. J Immunol 174: 4670-4607, 2005.
-
(2005)
J Immunol
, vol.174
, pp. 4607-4670
-
-
Cham, C.M.1
Gajewski, T.F.2
-
6
-
-
41849125939
-
An under-recognized complication of treatment of acute severe asthma
-
Creagh-Brown BC, Ball J. An under-recognized complication of treatment of acute severe asthma. Am J Emerg Med 26: 514.e1-e3, 2008.
-
(2008)
Am J Emerg Med
, vol.26
, Issue.514
-
-
Creagh-Brown, B.C.1
Ball, J.2
-
7
-
-
70350728803
-
MYC-induced cancer cell energy metabolism and therapeutic opportunities
-
Dang CV, Le A, Gao P. MYC-induced cancer cell energy metabolism and therapeutic opportunities. Clin Cancer Res 15: 6479-6483, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 6479-6483
-
-
Dang, C.V.1
Le, A.2
Gao, P.3
-
8
-
-
37449024702
-
The biology of cancer: Metabolic reprogramming fuels cell growth and proliferation
-
DeBerardinis RJ, Lum JJ, Hatzivassiliou G, Thompson CB. The biology of cancer: metabolic reprogramming fuels cell growth and proliferation. Cell Metab 7: 11-20, 2008.
-
(2008)
Cell Metab
, vol.7
, pp. 11-20
-
-
Deberardinis, R.J.1
Lum, J.J.2
Hatzivassiliou, G.3
Thompson, C.B.4
-
9
-
-
78650885452
-
The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway
-
Fang M, Shen Z, Huang S, Zhao L, Chen S, Mak TW, Wang X. The ER UDPase ENTPD5 promotes protein N-glycosylation, the Warburg effect, and proliferation in the PTEN pathway. Cell 143: 711-724, 2010.
-
(2010)
Cell
, vol.143
, pp. 711-724
-
-
Fang, M.1
Shen, Z.2
Huang, S.3
Zhao, L.4
Chen, S.5
Mak, T.W.6
Wang, X.7
-
10
-
-
34247352844
-
Inhibitory effect of tumor cell-derived lactic acid on human T cells
-
Fischer K, Hoffmann P, Voelkl S, Meidenbauer N, Ammer J, Edinger M, Gottfried E, Schwarz S, Rothe G, Hoves S, Renner K, Timischl B, Mackensen A, Kunz-Schughart L, Andreesen R, Krause SW, Kreutz M. Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood 109: 3812-3819, 2007.
-
(2007)
Blood
, vol.109
, pp. 3812-3819
-
-
Fischer, K.1
Hoffmann, P.2
Voelkl, S.3
Meidenbauer, N.4
Ammer, J.5
Edinger, M.6
Gottfried, E.7
Schwarz, S.8
Rothe, G.9
Hoves, S.10
Renner, K.11
Timischl, B.12
Mackensen, A.13
Kunz-Schughart, L.14
Andreesen, R.15
Krause, S.W.16
Kreutz, M.17
-
11
-
-
1842581892
-
Regulation of T lymphocyte metabolism
-
Frauwirth KA, Thompson CB. Regulation of T lymphocyte metabolism. J Immunol 172: 4661-4665, 2004.
-
(2004)
J Immunol
, vol.172
, pp. 4661-4665
-
-
Frauwirth, K.A.1
Thompson, C.B.2
-
12
-
-
63449096467
-
Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma
-
Goplen N, Karim MZ, Liang Q, Gorska MM, Rozario S, Guo L, Alam R. Combined sensitization of mice to extracts of dust mite, ragweed, and Aspergillus species breaks through tolerance and establishes chronic features of asthma. J Allergy Clin Immunol 123: 925-932.e11, 2009.
-
(2009)
J Allergy Clin Immunol
, vol.123
, pp. 925-932
-
-
Goplen, N.1
Karim, M.Z.2
Liang, Q.3
Gorska, M.M.4
Rozario, S.5
Guo, L.6
Alam, R.7
-
13
-
-
1342321661
-
Unc119, a novel activator of Lck/Fyn, is essential for T cell activation
-
Gorska MM, Stafford SJ, Cen O, Sur S, Alam R. Unc119, a novel activator of Lck/Fyn, is essential for T cell activation. J Exp Med 199: 369-379, 2004.
-
(2004)
J Exp Med
, vol.199
, pp. 369-379
-
-
Gorska, M.M.1
Stafford, S.J.2
Cen, O.3
Sur, S.4
Alam, R.5
-
14
-
-
34447258367
-
MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation
-
Gorska MM, Liang Q, Stafford SJ, Goplen N, Dharajiya N, Guo L, Sur S, Gaestel M, Alam R. MK2 controls the level of negative feedback in the NF-kappaB pathway and is essential for vascular permeability and airway inflammation. J Exp Med 204: 1637-1652, 2007.
-
(2007)
J Exp Med
, vol.204
, pp. 1637-1652
-
-
Gorska, M.M.1
Liang, Q.2
Stafford, S.J.3
Goplen, N.4
Dharajiya, N.5
Guo, L.6
Sur, S.7
Gaestel, M.8
Alam, R.9
-
15
-
-
68149165398
-
Uncoordinated 119 protein controls trafficking of Lck via the Rab11 endosome and is critical for immunological synapse formation
-
Gorska MM, Liang Q, Karim Z, Alam R. Uncoordinated 119 protein controls trafficking of Lck via the Rab11 endosome and is critical for immunological synapse formation. J Immunol 183: 1675-1684, 2009.
-
(2009)
J Immunol
, vol.183
, pp. 1675-1684
-
-
Gorska, M.M.1
Liang, Q.2
Karim, Z.3
Alam, R.4
-
16
-
-
77952746727
-
Uncoordinated 119 preferentially induces Th2 differentiation and promotes the development of asthma
-
Gorska MM, Goplen N, Liang Q, Alam R. Uncoordinated 119 preferentially induces Th2 differentiation and promotes the development of asthma. J Immunol 184: 4488-4496, 2010.
-
(2010)
J Immunol
, vol.184
, pp. 4488-4496
-
-
Gorska, M.M.1
Goplen, N.2
Liang, Q.3
Alam, R.4
-
17
-
-
0015881369
-
Glucose metabolism in the rat small intestine: The effect of glucose analogues on hexokinase activity
-
Jones GM, Mayer RJ. Glucose metabolism in the rat small intestine: the effect of glucose analogues on hexokinase activity. Biochem J 132: 125-128, 1973.
-
(1973)
Biochem J
, vol.132
, pp. 125-128
-
-
Jones, G.M.1
Mayer, R.J.2
-
18
-
-
11244347171
-
Glycolytic enzymes can modulate cellular life span
-
Kondoh H, Lleonart ME, Gil J, Wang J, Degan P, Peters G, Martinez D, Carnero A, Beach D. Glycolytic enzymes can modulate cellular life span. Cancer Res 65: 177-185, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 177-185
-
-
Kondoh, H.1
Lleonart, M.E.2
Gil, J.3
Wang, J.4
Degan, P.5
Peters, G.6
Martinez, D.7
Carnero, A.8
Beach, D.9
-
19
-
-
33745149291
-
p53 regulates mitochondrial respiration
-
Matoba S, Kang JG, Patino WD, Wragg A, Boehm M, Gavrilova O, Hurley PJ, Bunz F, Hwang PM. p53 regulates mitochondrial respiration. Science 312: 1650-1653, 2006.
-
(2006)
Science
, vol.312
, pp. 1650-1653
-
-
Matoba, S.1
Kang, J.G.2
Patino, W.D.3
Wragg, A.4
Boehm, M.5
Gavrilova, O.6
Hurley, P.J.7
Bunz, F.8
Hwang, P.M.9
-
20
-
-
0022246207
-
Partial pyruvate decarboxylase deficiency with profound lactic acidosis and hyperammonemia: Responses to dichloroacetate and benzoate
-
McCormick K, Viscardi RM, Robinson B, Heininger J. Partial pyruvate decarboxylase deficiency with profound lactic acidosis and hyperammonemia: responses to dichloroacetate and benzoate. Am J Med Genet 22: 291-299, 1985.
-
(1985)
Am J Med Genet
, vol.22
, pp. 291-299
-
-
McCormick, K.1
Viscardi, R.M.2
Robinson, B.3
Heininger, J.4
-
21
-
-
79953172571
-
Cutting edge: Distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. J Immunol 186: 3299-3303, 2011.
-
(2011)
J Immunol
, vol.186
, pp. 3299-3303
-
-
Michalek, R.D.1
Gerriets, V.A.2
Jacobs, S.R.3
Macintyre, A.N.4
Maciver, N.J.5
Mason, E.F.6
Sullivan, S.A.7
Nichols, A.G.8
Rathmell, J.C.9
-
22
-
-
33746877057
-
Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs
-
Ohta S. Contribution of somatic mutations in the mitochondrial genome to the development of cancer and tolerance against anticancer drugs. Oncogene 25: 4768-4776, 2006.
-
(2006)
Oncogene
, vol.25
, pp. 4768-4776
-
-
Ohta, S.1
-
23
-
-
0036333113
-
Lactic acidosis in asthma: Report of two cases and review of the literature
-
Prakash S, Mehta S. Lactic acidosis in asthma: report of two cases and review of the literature. Can Respir J 9: 203-208, 2002.
-
(2002)
Can Respir J
, vol.9
, pp. 203-208
-
-
Prakash, S.1
Mehta, S.2
-
24
-
-
60549111398
-
Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis
-
Robey RB, Hay N. Is Akt the "Warburg kinase"?-Akt-energy metabolism interactions and oncogenesis. Semin Cancer Biol 19: 25-31, 2009.
-
(2009)
Semin Cancer Biol
, vol.19
, pp. 25-31
-
-
Robey, R.B.1
Hay, N.2
-
25
-
-
33746947313
-
Lactic acidemia and mitochondrial disease
-
Robinson BH. Lactic acidemia and mitochondrial disease. Mol Genet Metab 89: 3-13, 2006.
-
(2006)
Mol Genet Metab
, vol.89
, pp. 3-13
-
-
Robinson, B.H.1
-
26
-
-
20344370257
-
Elevated plasma lactate level associated with high dose inhaled albuterol therapy in acute severe asthma
-
Rodrigo GJ, Rodrigo C. Elevated plasma lactate level associated with high dose inhaled albuterol therapy in acute severe asthma. Emerg Med J 22: 404-408, 2005.
-
(2005)
Emerg Med J
, vol.22
, pp. 404-408
-
-
Rodrigo, G.J.1
Rodrigo, C.2
-
27
-
-
0017290106
-
Metabolic acidosis in status asthmaticus
-
Roncoroni AJ, Adrougué HJ, De Obrutsky CW, Marchisio ML, Herrera MR. Metabolic acidosis in status asthmaticus. Respiration 33: 85-94, 1976.
-
(1976)
Respiration
, vol.33
, pp. 85-94
-
-
Roncoroni, A.J.1
Adrougué, H.J.2
de Obrutsky, C.W.3
Marchisio, M.L.4
Herrera, M.R.5
-
28
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi LZ, Wang R, Huang G, Vogel P, Neale G, Green DR, Chi H. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. J Exp Med 208: 1367-1376, 2011.
-
(2011)
J Exp Med
, vol.208
, pp. 1367-1376
-
-
Shi, L.Z.1
Wang, R.2
Huang, G.3
Vogel, P.4
Neale, G.5
Green, D.R.6
Chi, H.7
-
29
-
-
61449221901
-
Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation
-
Samuvel DJ, Sundararaj KP, Nareika A, Lopes-Virella MF, Huang Y. Lactate boosts TLR4 signaling and NF-kappaB pathway-mediated gene transcription in macrophages via monocarboxylate transporters and MD-2 up-regulation. J Immunol 182: 2476-2484, 2009.
-
(2009)
J Immunol
, vol.182
, pp. 2476-2484
-
-
Samuvel, D.J.1
Sundararaj, K.P.2
Nareika, A.3
Lopes-Virella, M.F.4
Huang, Y.5
-
30
-
-
47249118348
-
Tumor-secreted lactic acid promotes IL-23/IL-17 proinflamma-tory pathway
-
Shime H, Yabu M, Akazawa T, Kodama K, Matsumoto M, Seya T, Inoue N. Tumor-secreted lactic acid promotes IL-23/IL-17 proinflamma-tory pathway. J Immunol 180: 7175-7183, 2008.
-
(2008)
J Immunol
, vol.180
, pp. 7175-7183
-
-
Shime, H.1
Yabu, M.2
Akazawa, T.3
Kodama, K.4
Matsumoto, M.5
Seya, T.6
Inoue, N.7
-
31
-
-
40849131523
-
Evaluation of long-term treatment of children with congenital lactic acidosis with dichloroacetate
-
Stacpoole PW, Gilbert LR, Neiberger RE, Carney PR, Valenstein E, Theriaque DW, Shuster JJ. Evaluation of long-term treatment of children with congenital lactic acidosis with dichloroacetate. Pediatrics 121: e1223-e1228, 2008.
-
(2008)
Pediatrics
, vol.121
-
-
Stacpoole, P.W.1
Gilbert, L.R.2
Neiberger, R.E.3
Carney, P.R.4
Valenstein, E.5
Theriaque, D.W.6
Shuster, J.J.7
-
32
-
-
12444279265
-
On the origin of cancer cells
-
Warburg O. On the origin of cancer cells. Science 123: 309-314, 1956.
-
(1956)
Science
, vol.123
, pp. 309-314
-
-
Warburg, O.1
-
33
-
-
0036974970
-
Lactic acidosis and status asthmaticus: How common in pediatrics?
-
Yousef E, McGeady SJ. Lactic acidosis and status asthmaticus: how common in pediatrics? Ann Allergy Asthma Immunol 89: 585-588, 2002.
-
(2002)
Ann Allergy Asthma Immunol
, vol.89
, pp. 585-588
-
-
Yousef, E.1
McGeady, S.J.2
|