WNT stimulation dissociates a frizzled 4 inactive-state complex with Gα12/13

Molecular Pharmacology

Volumn 90, Issue 4, 2016, Pages 447-459

  Arthofer, Elisa ^a,b   Hot, Belma ^a   Petersen, Julian ^a   Strakova, Katerina ^a,c   Jäger, Stefan ^a   Grundmann, Manuel ^d   Kostenis, Evi ^d   Gutkind, J Silvio ^e   Schulte, Gunnar ^a,c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c MASARYK UNIVERSITY   (Czech Republic)

^d UNIVERSITY OF BONN   (Germany)

^e San Diego   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS MODULATOR; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; SECRETED FRIZZLED RELATED PROTEIN 4; WNT PROTEIN; WNT10B PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN; WNT7A PROTEIN; DISHEVELLED PROTEIN; FRIZZLED PROTEIN; FZD4 PROTEIN, HUMAN; PROTEIN BINDING;

ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DISSOCIATION; EMBRYO; GENE OVEREXPRESSION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; INTRACELLULAR SPACE; MOLECULAR WEIGHT; NEGATIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN IMMOBILIZATION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; WNT SIGNALING PATHWAY; CHEMISTRY; DRUG EFFECTS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; HEK293 CELL LINE; METABOLISM; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

DISHEVELLED PROTEINS; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; FLUORESCENCE RESONANCE ENERGY TRANSFER; FRIZZLED RECEPTORS; GREEN FLUORESCENT PROTEINS; GTP-BINDING PROTEIN ALPHA SUBUNITS, G12-G13; HEK293 CELLS; HUMANS; PROTEIN BINDING; PROTEIN DOMAINS; RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 84987829272     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.116.104919     Document Type: Article

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