Frizzleds and WNT/β-catenin signaling - The black box of ligand-receptor selectivity, complex stoichiometry and activation kinetics

European Journal of Pharmacology

Volumn 763, Issue , 2015, Pages 191-195

  Schulte, Gunnar ^a,b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MASARYK UNIVERSITY   (Czech Republic)

Author keywords

Canonical signaling; Class Frizzled; GPCR; LRP5 6; Receptor complex

Indexed keywords

BETA CATENIN; FRIZZLED PROTEIN; HETEROTRIMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MEMBRANE PROTEIN; PROTEIN GPR124; PROTEIN TSPAN12; UNCLASSIFIED DRUG; WNT PROTEIN; LIGAND;

ARTICLE; CELL JUNCTION; COMPLEX FORMATION; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; SIGNALOSOME; STOICHIOMETRY; ANIMAL; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; METABOLISM; PROTEIN MULTIMERIZATION; WNT SIGNALING PATHWAY;

ANIMALS; FRIZZLED RECEPTORS; HUMANS; KINETICS; LIGANDS; PROTEIN MULTIMERIZATION; SUBSTRATE SPECIFICITY; WNT SIGNALING PATHWAY;

EID: 84942370943     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2015.05.031     Document Type: Article

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